CATH Domain: 1wm3A00 XML data for domain: 1wm3A00

Molscript image for 1wm3A00
1wm3A00
PDB coordinates for domain 1wm3A00

PDB 1wm3, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.10 Roll
3.10.20 Ubiquitin-like (UB roll)
3.10.20.90 Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 Gene3D
3.10.20.90.4
3.10.20.90.4.1
3.10.20.90.4.1.1
3.10.20.90.4.1.1.1
3.10.20.90.4.1.1.1.1

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Segment boundaries for domain 1wm3A00

Chopping figure for domain 1wm3A00
DomainStart PDB ResidueStop PDB Residue
1wm3A00 17 88

Structural Neighbourhood (49 entries)

There are 49 matching structural neighberhood comparisons for CATH ID 3.10.20.90.4.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 49 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1wywB00 94.14 Nuclear poreNegative regulation of transcriptionSmall ubiquitin-related modifier 1Protein bindingProtein sumoylation 3.10.20.90 79 51 91 0.77 0.84
1y8rC00 92.22 Nuclear poreNegative regulation of transcriptionSmall ubiquitin-related modifier 1Protein sumoylationProtein binding 3.10.20.90 84 51 85 0.73 0.85
1wh3A01 92.05 CytoplasmDNA binding59 kDa 2'-5'-oligoadenylate synthase-like proteinThyroid hormone receptor bindingNucleolus 3.10.20.90 71 22 98 1.26 1.28
1yqbA01 90.80 Ubiquilin-3Homo sapiensUbiquilin 3.10.20.90 71 18 98 1.38 1.40
1z2mA02 90.55 RIG-I-like receptor signaling pathwayInterferon-induced 17 kDa proteinISG15-protein conjugationHomo sapiensUbiquitin cross-reactive protein 3.10.20.90 77 11 93 1.29 1.38
2fazA00 90.43 E3 ubiquitin-protein ligase UHRF1RNA polymerase II transcription factor activityProtein bindingCell proliferationSequence-specific DNA binding transcription factor activity 3.10.20.90 77 19 93 1.46 1.56
2kd0A01 89.82 LRR repeats and ubiquitin-like domain-containing protein At2g30105Arabidopsis thaliana 3.10.20.90 71 15 98 1.59 1.61
1m94A00 89.70 Ubiquitin-like protein 5Protein modification processProtein bindingNuclear mRNA splicing, via spliceosomeMating projection 3.10.20.90 73 15 98 1.93 1.96
2zeqA00 87.61 Synaptic transmission, glutamatergicLearningAdult locomotory behaviorParkinson's diseaseDopamine metabolic process 3.10.20.90 78 18 92 1.80 1.95
1h4rA01 87.11 Negative regulation of cell-cell adhesionSchwann cell proliferationCytoskeletonNucleolusEarly endosome 3.10.20.90 78 11 91 1.69 1.86
1wx9A00 86.68 Large proline-rich protein BAT3Homo sapiensProtein binding 3.10.20.90 86 8 82 1.83 2.22
1p1aA00 86.51 Nucleotide excision repairUV excision repair protein RAD23 homolog BSingle-stranded DNA bindingHomo sapiensUV excision repair protein RAD23 3.10.20.90 85 9 84 1.77 2.09
2he7A01 86.38 Tight junctionErythrocyte membrane protein band 4.1Homo sapiensBand 4.1-like protein 3Cell-cell junction 3.10.20.90 80 12 90 1.77 1.97
1z2mA01 85.20 RIG-I-like receptor signaling pathwayInterferon-induced 17 kDa proteinISG15-protein conjugationHomo sapiensUbiquitin cross-reactive protein 3.10.20.90 75 16 94 2.17 2.29
3ge3C00 84.58 Pseudomonas mendocinaToluene-4-monooxygenase system protein B 3.10.20.270 83 13 86 2.61 3.01
1oqyA01 84.42 Nucleotide excision repairNucleotide-excision repairUV excision repair protein RAD23 homolog ASingle-stranded DNA bindingHomo sapiens 3.10.20.90 79 5 91 2.03 2.23
1c1yB00 84.11 RAF proto-oncogene serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayProtein binding 3.10.20.90 77 9 89 2.45 2.73
1h8cA00 83.78 Cytoplasmic sequestering of NF-kappaBHeat shock protein bindingFAS-associated factor 1CytosolPositive regulation of protein complex assembly 3.10.20.90 82 5 86 2.13 2.46
1uh6A00 83.42 Mus musculusUbiquitin-like protein 5Ubiquitin-like protein 5 3.10.20.90 100 13 72 1.93 2.68
2fnjB00 83.06 Renal cell carcinomaPathways in cancerUbiquitin mediated proteolysisMus musculusTranscription elongation factor B polypeptide 2 3.10.20.90 98 11 72 1.66 2.29
1v5oA00 83.06 Mus musculusDNA damage-inducible protein 1Protein DDI1 homolog 1 3.10.20.90 102 11 70 1.91 2.71
1t0yA00 82.93 Caenorhabditis elegansTubulin-specific chaperone B 3.10.20.90 90 13 80 2.20 2.75
1oeyA00 82.81 Protein C-terminus bindingNeutrophil cytosol factor 2Leukocyte transendothelial migrationCellular defense responseSuperoxide anion generation 3.10.20.90 78 16 87 2.42 2.78
1wxmA01 82.55 Bladder cancerPathways in cancerNon-small cell lung cancerAcute myeloid leukemiaProtein binding 3.10.20.90 71 8 90 3.06 3.39
1wgdA00 82.54 Endoplasmic reticulum membraneHomo sapiensHomocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 proteinProtein binding 3.10.20.90 93 12 77 2.19 2.83
2rd0A01 82.51 Jak-STAT signaling pathwayAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.10.20.90 100 13 71 2.11 2.97
1wmhA00 82.26 Tight junctionInsulin signaling pathwayEndocytosisVesicle-mediated transportProtein binding 3.10.20.240 83 11 85 2.44 2.85
2nptB01 82.02 Mitogen-activated protein kinase kinase kinase 2Gap junctionMitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]GnRH signaling pathwayMAPK signaling pathway 3.10.20.240 81 13 83 2.46 2.93
1lfdA00 81.95 Rattus norvegicusRal guanine nucleotide dissociation stimulatorSmall GTPase mediated signal transduction 3.10.20.90 87 5 82 2.70 3.26
1v5tA00 81.73 Mus musculusUbiquitin-like domain-containing CTD phosphatase 1Protein phosphatase [EC:3.1.3.16] 3.10.20.90 90 11 78 2.05 2.60
1se9A00 81.59 Membrane-anchored ubiquitin-fold protein 1Arabidopsis thaliana 3.10.20.90 101 15 71 1.86 2.61
1k8rB00 81.58 Plasma membraneInduction of conjugation upon nitrogen starvationProtein bindingSchizosaccharomyces pombeProtein kinase byr2 3.10.20.90 82 9 71 2.61 3.63
1ip9A00 81.58 MAPK signaling pathway - yeastMating projection tipIdentical protein bindingEstablishment of cell polarityPhosphatidylinositol-3-phosphate binding 3.10.20.240 85 13 80 2.45 3.06
1wmhB00 80.89 Partitioning defective 6 homolog alphaTranscription factor bindingViral reproductionHomo sapiens 3.10.20.240 82 8 86 2.69 3.11
1v86A00 80.87 Mus musculusPutative uncharacterized protein 3.10.20.90 95 15 73 1.97 2.67
2r2oA00 80.46 Semaphorin receptor bindingPlexin BSemaphorin receptor activityHomo sapiensPlexin-B1 3.10.20.90 98 11 72 2.37 3.27
2kfjA00 80.28 Cell division control protein 24MAPK signaling pathway - yeastMating projection tipInvasive growth in response to glucose limitationCell division control protein 24 3.10.20.240 86 6 81 3.20 3.93
2c60A01 80.08 Neurotrophin signaling pathwayMitogen-activated protein kinase kinase kinase 3MAPKKK cascadeProtein bindingPositive regulation of I-kappaB kinase/NF-kappaB cascade 3.10.20.240 77 8 81 2.74 3.35
1v2yA00 79.69 U11/U12 small nuclear ribonucleoprotein 25 kDa proteinMus musculus 3.10.20.90 105 13 68 2.23 3.25
1j8cA00 79.59 CytoplasmPlasma membraneHomo sapiensUbiquilinUbiquilin-2 3.10.20.90 103 18 68 2.12 3.08
3kh0A00 79.52 Ral guanine nucleotide dissociation stimulatorSmall GTPase regulator activityHomo sapiens 3.10.20.90 102 5 70 2.64 3.74
2nptC01 78.18 Homo sapiensProtein bindingDual specificity mitogen-activated protein kinase kinase 5 3.10.20.240 88 5 77 2.85 3.69
3d32B00 77.77 Regulation of autophagySynaptic transmissionPlasma membraneProtein targetingGamma-aminobutyric acid receptor-associated protein 3.10.20.90 116 13 62 2.68 4.32
1wxsA00 77.38 CytoplasmUbiquitin-fold modifier 1NucleusProtein ufmylationHomo sapiens 3.10.20.90 88 9 78 3.30 4.21
1oeyL00 77.21 Protein dimerization activityLeukocyte transendothelial migrationNeutrophil cytosolic factor 4CytosolNADPH oxidase complex 3.10.20.240 96 8 71 2.99 4.16
1y8qD03 76.98 SUMO-activating enzyme subunit 2Ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19]Enzyme activator activityHomo sapiensUbiquitin mediated proteolysis 3.10.290.20 105 8 58 1.88 3.24
2zjdA00 76.79 Microtubule-associated protein 1 light chainHomo sapiensMicrotubule-associated proteins 1A/1B light chain 3BProtein binding 3.10.20.90 121 12 59 2.61 4.39
1i42A00 76.69 Rattus norvegicusGolgi organizationCellular membrane fusionNSFL1 cofactor p47Protein binding 3.10.20.90 89 9 78 3.39 4.31
1s3sH00 76.03 Rattus norvegicusGolgi organizationCellular membrane fusionNSFL1 cofactor p47Protein binding 3.10.20.90 107 11 64 2.15 3.33
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Displaying entries 1 to 49 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1wm3A00
HINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQ
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1wm3A00
HINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQ
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 01 Nov 2006 14:43

Assigning to "3.10.20.90" based on similarity with "2bf8B00"

Flow stage update by auto on 31 Oct 2006 01:52

No in_process hits for Domain "1wm3A00" ready to be processed

Flow stage update by auto on 31 Oct 2006 01:52

NW result present for Domain "1wm3A00"

Flow stage update by auto on 27 Oct 2006 01:23

All required files are present for Domain "1wm3A00"

Flow stage update by auto on 26 Oct 2006 06:42

Beginning processing for Domain "1wm3A00"

Insertion by cuff on 25 Oct 2006 16:52

batch of nice choppings