CATH Domain: 1wakA01 XML data for domain: 1wakA01

Molscript image for 1wakA01
1wakA01
PDB coordinates for domain 1wakA01

PDB 1wak, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.200 Phosphorylase Kinase; domain 1
3.30.200.20 Phosphorylase Kinase; domain 1 Gene3D
3.30.200.20.18
3.30.200.20.18.1
3.30.200.20.18.1.1
3.30.200.20.18.1.1.1
3.30.200.20.18.1.1.1.1

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Segment boundaries for domain 1wakA01

Chopping figure for domain 1wakA01
DomainStart PDB ResidueStop PDB Residue
1wakA01 63 133
1wakA01 145 167
1wakA02 134 144
1wakA02 168 655

Structural Neighbourhood (41 entries)

There are 41 matching structural neighberhood comparisons for CATH ID 3.30.200.20.18.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 41 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3f61A01 87.77 Serine/threonine-protein kinase pknBSerine/threonine protein kinase, bacterial [EC:2.7.11.1]Mycobacterium tuberculosis 3.30.200.20 91 18 92 2.73 2.95
2wtjA01 87.10 DNA damage response, signal transduction resulting in induction of apoptosisSenescenceSerine/threonine-protein kinase Chk2PML bodyProtein binding 3.30.200.20 79 20 82 2.75 3.33
1tkiA01 87.00 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 3.30.200.20 84 23 85 2.21 2.57
1xbbA01 86.65 T cell receptor complexTyrosine-protein kinase SYKOrgan morphogenesisLeukocyte cell-cell adhesionCell proliferation 3.30.200.20 83 21 83 4.05 4.84
2zv2A01 86.63 Calcium ion bindingRegulation of protein kinase activityPositive regulation of transcriptionMAPKKK cascadeCytoplasm 3.30.200.20 77 25 80 2.29 2.85
1x8bA01 86.13 Homo sapiensWee1-like protein kinaseProtein binding 3.30.200.20 84 16 86 2.99 3.44
3d5vA01 85.83 Danio rerioPolo-like kinase 3.30.200.20 92 27 89 2.11 2.37
1q5kA01 85.81 Hedgehog signaling pathwayNeurotrophin signaling pathwayAlzheimer's diseaseT cell receptor signaling pathwayER overload response 3.30.200.20 95 16 82 2.76 3.36
2wtkC01 85.75 NucleusSerine/threonine-protein kinase 11Cell cycle arrestProtein bindingSerine/threonine-protein kinase 11 [EC:2.7.11.9] 3.30.200.20 89 23 80 2.10 2.61
2i6lA01 85.69 Protein phosphorylationMitogen-activated protein kinase 6Homo sapiensSignal transductionMitogen-activated protein kinase 4/6 [EC:2.7.11.24] 3.30.200.20 91 21 85 3.60 4.19
3hmmA01 85.66 Type II transforming growth factor beta receptor bindingPeptidyl-threonine phosphorylationPositive regulation of cellular component movementPathway-restricted SMAD protein phosphorylationResponse to cholesterol 3.30.200.20 84 15 83 2.62 3.13
3fhrA01 85.52 Response to stressMAP kinase kinase activityNucleusMitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]MAPK signaling pathway 3.30.200.20 80 16 82 2.30 2.78
2a19C01 85.52 Eukaryotic translation initiation factor 2alpha kinase activityProtein phosphatase type 2A regulator activityInterferon-induced, double-stranded RNA-activated protein kinaseProtein bindingNegative regulation of osteoblast proliferation 3.30.200.20 95 17 88 3.05 3.45
1xwsA01 85.42 Transcription factor bindingPositive regulation of cyclin-dependent protein kinase activity involved in G1/SManganese ion bindingNegative regulation of apoptosisProtein binding 3.30.200.20 92 22 84 2.40 2.83
2jamA01 85.39 Calcium/calmodulin-dependent protein kinase type 1GHomo sapiensCalcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] 3.30.200.20 75 28 78 2.22 2.84
2acxA02 85.39 G protein-coupled receptor kinase 6Homo sapiensRegulation of G-protein coupled receptor protein signaling pathway 3.30.200.20 91 19 86 3.80 4.37
1zy4A01 85.07 Eukaryotic translation initiation factor 2alpha kinase activityProtein bindingSerine/threonine-protein kinase GCN2DNA damage checkpointRegulation of translational initiation 3.30.200.20 94 18 89 2.98 3.33
2h6dA01 84.93 Insulin signaling pathwayHypertrophic cardiomyopathy (HCM)Adipocytokine signaling pathwayRegulation of autophagyMTOR signaling pathway 3.30.200.20 86 23 85 2.63 3.06
3c0iA01 84.90 Actin cytoskeletonGuanylate kinase activityPeripheral plasma membrane protein CASKCell adhesionHomo sapiens 3.30.200.20 88 25 85 2.70 3.14
2ac3A01 84.57 MAP kinase-interacting serine/threonine-protein kinase 2ATP bindingProtein phosphorylationHomo sapiensProtein serine/threonine kinase activity 3.30.200.20 80 17 80 2.23 2.77
3f3zA01 84.25 Cryptosporidium parvum Iowa IICalcium-dependent protein kinase [EC:2.7.11.1]Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands 3.30.200.20 81 19 83 2.33 2.78
2clqA01 84.16 Induction of apoptosis by extracellular signalsProtein homodimerization activityMitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]Neurotrophin signaling pathwayATP binding 3.30.200.20 85 22 80 2.25 2.80
3fpqA01 84.11 Rattus norvegicusSerine/threonine-protein kinase WNK1Protein bindingPotassium channel inhibitor activityATP binding 3.30.200.20 91 16 90 2.62 2.90
2rkuA01 84.11 Polo-like kinase 1 [EC:2.7.11.21]Polo kinase kinase activityProgesterone-mediated oocyte maturationCell proliferationOocyte meiosis 3.30.200.20 89 22 84 3.04 3.59
2jiiA01 83.23 Serine/threonine-protein kinase VRK3Homo sapiensProtein binding 3.30.200.20 110 4 74 2.50 3.35
2vgpB01 83.14 Serine/threonine-protein kinase 12-AHistone H3-S10 phosphorylationChromosome, centromeric regionProtein bindingChromatin 3.30.200.20 89 21 84 2.85 3.36
2r3iA01 82.85 Progesterone-mediated oocyte maturationPathways in cancerSmall cell lung cancerOocyte meiosisProstate cancer 3.30.200.20 76 27 76 2.42 3.18
2qkwB01 82.73 Solanum pimpinellifoliumProtein kinaseProtein binding 3.30.200.20 72 19 71 1.96 2.73
1omwA03 82.61 MembraneG-protein coupled receptor kinase activityNegative regulation of the force of heart contraction by chemical signalChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 3.30.200.20 107 19 72 2.32 3.18
1o6lA02 82.07 Jak-STAT signaling pathwayRAC-beta serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.200.20 117 20 67 3.06 4.53
2bkkA01 81.49 Aminoglycoside 3'-phosphotransferaseAminoglycoside 3'-phosphotransferase [EC:2.7.1.95]Enterococcus faecalis 3.30.200.20 90 7 86 3.95 4.54
2w5aA01 81.48 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]Regulation of mitosisSerine/threonine-protein kinase Nek2CentrosomeCentrosome separation 3.30.200.20 64 15 68 2.58 3.77
1ob3A01 81.46 Cyclin-dependent kinase [EC:2.7.11.22]Cell division control protein 2 homologPlasmodium falciparum K1 3.30.200.20 83 19 81 3.30 4.05
1kutB01 80.98 Thermotoga maritimaPhosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Metabolic pathways 3.30.200.20 88 9 61 1.78 2.87
1ckiA01 80.89 SpindleRattus norvegicusHedgehog signaling pathwaySoluble fractionCircadian rhythm - mammal 3.30.200.20 64 20 64 2.34 3.65
2ppqA01 80.61 Glycine, serine and threonine metabolismMetabolic pathwaysAgrobacterium tumefaciens str. C58Homoserine kinaseHomoserine kinase type II [EC:2.7.1.39] 3.30.200.20 93 7 81 3.33 4.07
2q83B01 80.60 Bacillus subtilisSpore coat protein ISpore coat protein I 3.30.200.20 97 13 80 3.70 4.60
2oo8X01 79.45 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 60 13 57 1.99 3.45
3kreA01 79.20 Phosphoribosylaminoimidazole-succinocarboxamide synthasePurine metabolismPhosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]Ehrlichia chaffeensis str. ArkansasMetabolic pathways 3.30.200.20 94 6 62 2.06 3.28
2jedB01 79.02 Protein kinase C theta typeProtein bindingT cell receptor signaling pathwayNovel protein kinase C [EC:2.7.11.13]Adipocytokine signaling pathway 3.30.200.20 125 19 62 2.52 4.04
3dzoA02 78.91 Toxoplasma gondiiRop2 protein 3.30.200.20 118 14 76 3.57 4.68
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Displaying entries 1 to 41 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1wakA01
CKYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNVQLLDDFKISG
VNGTHICMVFEV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1wakA01
CKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTETALDEIRLLKSVRNVQLLDDFKI
SGVNGTHICMVFEV
BLAST against CATH

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Domain History Events (6)

Domain assigned by auto on 28 Nov 2006 18:30

Assigning to "3.30.200.20" based on similarity with "1howA01"

Flow stage update by auto on 28 Nov 2006 18:22

No in_process hits for Domain "1wakA01" ready to be processed

Flow stage update by auto on 28 Nov 2006 18:22

NW result present for Domain "1wakA01"

Flow stage update by auto on 28 Nov 2006 18:22

All required files are present for Domain "1wakA01"

Flow stage update by auto on 28 Nov 2006 18:21

Beginning processing for Domain "1wakA01"

Insertion by cuff on 20 Nov 2006 17:03

nice batch of choppings