CATH Domain: 1w85G00

1w85G00

PDB 1w85, Chain G, Domain 0

CATH Code	Level Description	Links
3	Alpha Beta
3.40	3-Layer(aba) Sandwich
3.40.50	Rossmann fold
3.40.50.970		Gene3D
3.40.50.970.25
3.40.50.970.25.2
3.40.50.970.25.2.1
3.40.50.970.25.2.1.2
3.40.50.970.25.2.1.2.3

Structure
Sequence
History

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Segment boundaries for domain 1w85G00

Domain	Start PDB Residue	Stop PDB Residue
1w85G00	5	368

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (2 entries)

There are 2 matching structural neighberhood comparisons for CATH ID 3.40.50.970.25.2.1.2.3 (SIMAX score < 5)

Match Depth	Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
	1ni4A00	84.82	Citrate cycle (TCA cycle)Pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]Pyruvate metabolismProtein bindingMetabolic pathways	3.40.50.970	350	25	85	2.94	3.43
	1qs0A00	84.26	2-oxoisovalerate dehydrogenase subunit alphaProtein bindingPseudomonas putida	3.40.50.970	395	33	79	1.64	2.07

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Domain ATOM Sequence

>pdb|1w85G00
FQFPFAEQLEKVAEQFPTFQILNEEGEVVNEEAMPELSDEQLKELMRRMVYTRILDQRSISLNRQGRLGFYAPTAGQEAS
QIASHFALEKEDFILPGYRDVPQIIWHGLPLYQAFLFSRGHFHGNQIPEGVNVLPPQIIIGAQYIQAAGVALGLKMRGKK
AVAITYTGDGGTSQGDFYEGINFAGAFKAPAIFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYAA
VKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRFRKFLEAKGLWSEEEENNVIEQAKEE
IKEAIKKADETPKQKVTDLISIMFEELPFNLKEQYEIYKEKESK

BLAST against CATH

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Domain COMBS Sequence

>pdb|1w85G00
GVKTFQFPFAEQLEKVAEQFPTFQILNEEGEVVNEEAMPELSDEQLKELMRRMVYTRILDQRSISLNRQGRLGFYAPTAG
QEASQIASHFALEKEDFILPGYRDVPQIIWHGLPLYQAFLFSRGHFHGNQIPEGVNVLPPQIIIGAQYIQAAGVALGLKM
RGKKAVAITYTGDGGTSQGDFYEGINFAGAFKAPAIFVVQNNRFAISTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLA
VYAAVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRFRKFLEAKGLWSEEEENNVIEQ
AKEEIKEAIKKADETPKQKVTDLISIMFEELPFNLKEQYEIYKEKESK

BLAST against CATH

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Domain History Events (11)

Domain assigned by auto on 01 Nov 2006 18:12

Assigning to "3.40.50.970" based on similarity with "1w85A00"