CATH Domain: 1w0tA00 XML data for domain: 1w0tA00

Molscript image for 1w0tA00
1w0tA00
PDB coordinates for domain 1w0tA00

PDB 1w0t, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.10 Orthogonal Bundle
1.10.10 Arc Repressor Mutant, subunit A
1.10.10.60 Homeodomain-like Gene3D
1.10.10.60.19
1.10.10.60.19.1
1.10.10.60.19.1.1
1.10.10.60.19.1.1.1
1.10.10.60.19.1.1.1.1

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Segment boundaries for domain 1w0tA00

Chopping figure for domain 1w0tA00
DomainStart PDB ResidueStop PDB Residue
1w0tA00 379 430

Structural Neighbourhood (34 entries)

There are 34 matching structural neighberhood comparisons for CATH ID 1.10.10.60.19.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 34 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1iv6A00 92.13 Positive regulation of mitotic cell cycleProtein homooligomerizationNegative regulation of telomerase activityTelomere maintenance via telomere shorteningG2/M transition of mitotic cell cycle 1.10.10.60 57 100 91 1.33 1.46
1gv2A02 90.84 Transcriptional activator MybNucleusEmbryonic digestive tract developmentProtein bindingMus musculus 1.10.10.60 46 23 86 1.32 1.53
1o4xA02 86.47 Sequence-specific DNA binding transcription factor activityPOU domain transcription factor, class 2Negative regulation of transcription, DNA-dependentSequence-specific DNA bindingTranscription repressor activity 1.10.10.60 53 5 86 2.60 3.00
1tc3C00 86.35 Caenorhabditis elegansTransposable element Tc3 transposase 1.10.10.60 51 7 90 2.30 2.54
2k9nA02 86.00 MYB24Trichomonas vaginalis 1.10.10.60 54 26 87 2.20 2.53
1au7A02 85.90 Positive regulation of transcription from RNA polymerase II promoterRattus norvegicusNucleusNegative regulation of transcription from RNA polymerase II promoterAdenohypophysis development 1.10.10.60 57 5 85 2.72 3.16
1e3oC02 85.81 POU domain transcription factor, class 2POU domain, class 2, transcription factor 1Protein bindingSequence-specific DNA binding transcription factor activityNegative regulation of transcription, DNA-dependent 1.10.10.60 48 10 86 2.53 2.92
1fexA00 85.38 Protein bindingTelomeric repeat-binding factor 2-interacting protein 1Protection from non-homologous end joining at telomereNegative regulation of telomere maintenanceCytoplasm 1.10.10.60 59 17 84 2.29 2.70
1irzA00 84.38 Regulation of anthocyanin metabolic processCytokinin mediated signaling pathwayNucleusSequence-specific DNA binding transcription factor activityArabidopsis thaliana 1.10.10.60 64 17 81 3.37 4.15
1b8iA00 84.06 Protein domain specific bindingDrosophila melanogasterPositive regulation of muscle organ developmentMesodermal cell fate specificationTranscription repressor activity 1.10.10.60 62 9 79 3.92 4.96
1mh3A03 83.88 Transcription corepressor activityMeiosis - yeastNucleusRegulation of transcription, mating-type specificMating-type protein A1 1.10.10.60 51 11 94 3.31 3.51
2dmqA01 83.70 LIM/homeobox protein Lhx9Homo sapiens 1.10.10.60 57 5 78 2.75 3.48
1gdtB03 82.45 Transposon gamma-delta resolvaseEscherichia coli K-12 1.10.10.60 45 4 84 3.87 4.57
2fq4A01 82.14 Transcriptional regulator, TetR familyBacillus cereus ATCC 14579 1.10.10.60 47 17 78 2.98 3.78
1t56A01 81.73 TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHRMycobacterium tuberculosis 1.10.10.60 46 2 76 3.17 4.12
1nk3P00 81.37 Ectoderm developmentTranscription factor bindingHomeobox protein vndBrain developmentDrosophila melanogaster 1.10.10.60 63 9 82 3.31 4.01
1b72A00 81.18 Homeobox protein Hox-B1Protein domain specific bindingHomeobox protein HoxA/B/D1Homo sapiens 1.10.10.60 68 5 76 3.02 3.95
1zkgA01 81.16 Thermotoga maritimaTranscriptional regulator, TetR family 1.10.10.60 46 4 76 3.40 4.42
1rr7A02 80.70 Middle operon regulatorEnterobacteria phage Mu 1.10.10.60 48 14 92 4.57 4.95
3bqzA01 80.23 HTH-type transcriptional regulator qacRStaphylococcus aureus subsp. aureus Mu50 1.10.10.60 49 4 82 3.58 4.33
1le8B00 79.59 Mating-type protein A2Meiosis - yeastMating-type protein ALPHA2Donor selectionSequence-specific DNA binding 1.10.10.60 74 13 68 2.95 4.28
1lfbA00 79.29 Positive regulation of transcription from RNA polymerase II promoterTranscription factor bindingRattus norvegicusNegative regulation of transcriptionDouble-stranded DNA binding 1.10.10.60 77 13 66 2.77 4.18
3bqyA01 78.98 Putative transcriptional regulatorStreptomyces coelicolor 1.10.10.60 48 6 88 3.82 4.32
1ic8A02 78.92 Promoter bindingProtein homodimerization activityNucleusPositive regulation of transcription, DNA-dependentGlucose homeostasis 1.10.10.60 74 13 68 2.59 3.76
1pufB00 78.83 CytoplasmPre-B-cell leukemia transcription factor 1Transcription factor bindingPre-B-cell leukemia transcription factorNucleus 1.10.10.60 73 11 69 3.05 4.37
3c2bA01 78.67 Agrobacterium tumefaciens str. C58Transcriptional regulator, TetR family 1.10.10.60 51 9 90 3.86 4.27
1wh5A00 78.67 Arabidopsis thalianaZF-HD homeobox protein At5g65410 1.10.10.60 80 13 65 2.81 4.32
1ignA01 78.44 Chromatin silencing at telomereProtein bindingMyb-like DNA-binding protein RAP1Protection from non-homologous end joining at telomereDNA-binding protein RAP1 1.10.10.60 93 17 51 2.48 4.80
1b8iB00 77.91 Oenocyte developmentLeg disc proximal/distal pattern formationTranscription factor complexBrain developmentDrosophila melanogaster 1.10.10.60 58 7 87 3.88 4.41
1ignB02 77.88 Chromatin silencing at telomereMyb-like DNA-binding protein RAP1Protein bindingProtection from non-homologous end joining at telomereDNA-binding protein RAP1 1.10.10.60 92 21 52 2.15 4.12
1hlvA01 77.04 Centromere protein BMajor centromere autoantigen BHomo sapiensChromosome, centromeric region 1.10.10.60 58 9 63 2.81 4.40
2hyjA01 76.90 Streptomyces coelicolorPutative tetR-family transcriptional regulator 1.10.10.60 46 2 69 2.38 3.44
1iufA02 75.80 Centromeric DNA bindingHistone modificationARS-binding protein 1Schizosaccharomyces pombeCondensed nuclear chromosome, centromeric region 1.10.10.60 64 5 71 3.43 4.77
1twfJ00 73.79 Pyrimidine metabolismPurine metabolismDNA-directed RNA Polymerase II subunit LRNA polymeraseProtein binding 1.10.10.60 65 5 72 3.59 4.96
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Displaying entries 1 to 34 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1w0tA00
KRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKL
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1w0tA00
KRQAWLWEEDKNLRSGVRKYGEGNWSKILLHYKFNNRTSVMLKDRWRTMKKLK
BLAST against CATH

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Domain History Events (5)

Domain assigned by auto on 28 Apr 2006 19:28

Assigning to "1.10.10.60" based on similarity with "1w0tB00" (NWSI: 100, NWO: 100, SPS: 98.52, SPO: 100, RMSD: 0.22)

Flow stage update by auto on 28 Apr 2006 17:50

NW result present for Domain "1w0tA00"

Flow stage update by auto on 28 Apr 2006 17:45

All required files are present for Domain "1w0tA00"

Flow stage update by auto on 27 Apr 2006 17:31

Beginning processing for Domain "1w0tA00"

Insertion by auto on 09 Mar 2006 09:51

Final ChopClose added based on similarity with "1ba50" [LEE: 0, LME: 0, MR: 1, LG: 1, SS: 92.05, SI: 98.1132075471698, SO: 98.1132075471698]