CATH Domain: 1uzmB00 XML data for domain: 1uzmB00

Molscript image for 1uzmB00
1uzmB00
PDB coordinates for domain 1uzmB00

PDB 1uzm, Chain B, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.11
3.40.50.720.11.1
3.40.50.720.11.1.1
3.40.50.720.11.1.1.1
3.40.50.720.11.1.1.1.1

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Segment boundaries for domain 1uzmB00

Chopping figure for domain 1uzmB00
DomainStart PDB ResidueStop PDB Residue
1uzmB00 9 245

Structural Neighbourhood (47 entries)

There are 47 matching structural neighberhood comparisons for CATH ID 3.40.50.720.11.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 47 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3grpD00 91.63 3-oxoacyl-(Acyl carrierprotein) reductaseBartonella henselae3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 209 33 95 1.58 1.65
2ztuB00 90.09 Pseudomonas fragiD(-)-3-hydroxybutyrate dehydrogenase 3.40.50.720 207 30 91 2.01 2.20
2ew8B00 89.74 Ethylbenzene degradation(S)-1-Phenylethanol dehydrogenaseAromatoleum aromaticum EbN1 3.40.50.720 228 32 89 1.70 1.91
1ydeN00 88.65 17-beta-hydroxysteroid dehydrogenase 14Testosterone 17-beta-dehydrogenase (NADP+) activityEstradiol 17-beta-dehydrogenase activitySteroid catabolic processHomo sapiens 3.40.50.720 240 29 83 1.50 1.79
2ekpA00 88.48 Pentose and glucuronate interconversionsThermus thermophilus HB82-deoxy-D-gluconate 3-dehydrogenase2-deoxy-D-gluconate 3-dehydrogenase [EC:1.1.1.125] 3.40.50.720 238 33 85 1.68 1.97
2rhcA00 88.44 Putative ketoacyl reductaseBiosynthesis of type II polyketide backboneStreptomyces coelicolorKetoacyl reductase [EC:1.3.1.-] 3.40.50.720 257 36 79 1.52 1.91
2ag5C00 88.10 NAD or NADH bindingMetabolic pathwaysButanoate metabolismCytoplasm3-hydroxybutyrate dehydrogenase type 2 3.40.50.720 244 27 83 1.92 2.30
1iy8A00 88.08 Leifsonia aquaticaLevodione reductase 3.40.50.720 258 37 80 1.57 1.96
1geeA00 88.08 Bacillus megateriumGlucose 1-dehydrogenase 3.40.50.720 261 33 80 1.99 2.47
1zk4A00 88.01 Lactobacillus brevisR-specific alcohol dehydrogenase 3.40.50.720 244 30 84 2.08 2.48
2a4kB01 87.67 3.40.50.720 196 32 88 2.55 2.89
2z1nA00 87.55 Aeropyrum pernix3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Putative dehydrogenaseFatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 237 35 88 2.88 3.27
1gz6B01 87.20 PeroxisomeRattus norvegicusPrimary bile acid biosynthesis3(or 17)beta-hydroxysteroid dehydrogenase activityPeroxisomal multifunctional enzyme type 2 3.40.50.720 219 28 87 2.44 2.80
2o23A00 87.12 3-hydroxyacyl-CoA dehydrogenase type-2Lipid metabolic process7-alpha-hydroxysteroid dehydrogenase activityPlasma membraneHomo sapiens 3.40.50.720 241 33 84 1.99 2.36
1fmcA00 87.08 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]7-alpha-hydroxysteroid dehydrogenaseEscherichia coli K-12Cytosol 3.40.50.720 255 30 82 1.94 2.36
1h5qA00 87.04 NADP-dependent mannitol dehydrogenaseAgaricus bisporus 3.40.50.720 260 32 80 2.04 2.53
1zemA00 87.00 Gluconobacter oxydansXylitol dehydrogenase 3.40.50.720 260 32 78 1.77 2.24
1spxA00 87.00 Caenorhabditis elegansProtein D1054.8, confirmed by transcript evidenceDetermination of adult lifespan 3.40.50.720 237 28 86 2.03 2.35
2zatA00 86.99 PeroxisomeDehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]Sus scrofaDehydrogenase/reductase SDR family member 4Retinol metabolism 3.40.50.720 251 34 82 1.87 2.26
1yxmC00 86.81 PeroxisomePeroxisomal trans-2-enoyl-CoA reductasePeroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]Homo sapiensBiosynthesis of unsaturated fatty acids 3.40.50.720 263 30 76 2.18 2.87
3iccA00 86.62 Bacillus anthracisOxidoreductase, short-chain dehydrogenase/reductase family 3.40.50.720 248 27 82 2.19 2.66
1cydA00 86.55 Carbonyl reductase (NADPH) activityArachidonic acid metabolismProtein tetramerizationCarbonyl reductase [NADPH] 2Metabolic pathways 3.40.50.720 242 28 83 1.95 2.32
2x9gD00 86.46 Pteridine reductaseTrypanosoma brucei brucei 3.40.50.720 248 24 81 2.06 2.54
1xq1A00 86.40 Arabidopsis thalianaTropinone reductase homolog At1g07440Response to cadmium ion 3.40.50.720 218 30 89 2.67 2.97
1ja9A00 86.32 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesis1,3,6,8-tetrahydroxynaphthalene reductaseBiosynthesis of unsaturated fatty acidsMagnaporthe grisea 3.40.50.720 259 34 79 2.30 2.89
2dknB00 86.27 3-alpha-hydroxysteroid dehydrogenasePseudomonas sp. B-0831 3.40.50.720 226 29 81 1.95 2.38
2p91C00 86.26 Enoyl-[acyl-carrier-protein] reductase [NADH]Aquifex aeolicus 3.40.50.720 228 19 85 2.07 2.42
1hxhA00 86.07 3-beta-hydroxysteroid dehydrogenaseComamonas testosteroni 3.40.50.720 253 29 82 3.90 4.74
3d7lA00 85.87 Listeria innocuaLin1944 protein 3.40.50.720 196 22 83 2.15 2.57
3gemD00 85.86 Pseudomonas syringae pv. phaseolicola 1448A[EC:1.-.-.-]Oxidoreductase, short chain dehydrogenase/reductase family 3.40.50.720 209 19 88 2.56 2.89
1zmtA00 85.85 3.40.50.720 252 25 78 1.87 2.38
1bdbA00 85.58 Biphenyl degradationCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [EC:1.3.1.56]Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenaseBurkholderia xenovorans LB400Metabolic pathways 3.40.50.720 267 28 77 2.02 2.62
3f1lB00 85.26 Uncharacterized oxidoreductase yciKEscherichia coli K-12 3.40.50.720 244 21 81 3.00 3.66
2qq5A00 85.18 NucleusGolgi apparatusEndoplasmic reticulumHomo sapiensDehydrogenase/reductase SDR family member 1 3.40.50.720 238 25 84 3.51 4.16
1ek6A02 84.02 Amino sugar and nucleotide sugar metabolismGalactose metabolismUDP-glucose 4-epimeraseProtein homodimerization activityUDP-glucose 4-epimerase activity 3.40.50.720 218 16 80 2.40 2.97
1jtvA00 83.15 CytoplasmEstradiol 17-beta-dehydrogenase 1Homo sapiens 3.40.50.720 278 30 71 2.54 3.53
1n7hA02 83.11 Amino sugar and nucleotide sugar metabolismGDPmannose 4,6-dehydratase [EC:4.2.1.47]Fructose and mannose metabolismCytosolMetabolic pathways 3.40.50.720 231 14 80 3.65 4.53
2h7iA00 82.65 Enoyl-[acyl-carrier-protein] reductase [NADH]Enoyl ACP reductase [EC:1.3.1.9]Mycobacterium tuberculosis 3.40.50.720 268 20 77 2.54 3.29
2oosB00 82.48 Enoyl-ACP reductasePlasmodium falciparum 3.40.50.720 283 16 71 2.24 3.14
1sbyA00 82.48 Scaptodrosophila lebanonensisAlcohol dehydrogenase 3.40.50.720 252 20 78 3.14 3.98
1e6uA01 82.06 Amino sugar and nucleotide sugar metabolismFructose and mannose metabolismMetabolic pathwaysGDP-L-fucose synthaseGDP-L-fucose synthase [EC:1.1.1.271] 3.40.50.720 220 15 78 2.63 3.34
1vl0B01 81.93 DTDP-4-dehydrorhamnose reductase, rfbD orthologDTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesis 3.40.50.720 200 14 78 3.68 4.68
1i24A01 81.92 Amino sugar and nucleotide sugar metabolismZinc ion bindingGlycolipid biosynthetic processChloroplastSulfotransferase activity 3.40.50.720 235 11 72 2.43 3.36
1ooeA00 81.90 Dihydropteridine reductase [EC:1.5.1.34]Caenorhabditis elegansProtein T03F6.1, confirmed by transcript evidenceFolate biosynthesisMetabolic pathways 3.40.50.720 235 16 84 3.29 3.90
1oaaA00 80.84 DeathRegulation of multicellular organism growthProtein homodimerization activitySepiapterin reductasePteridine metabolic process 3.40.50.720 259 20 77 3.14 4.03
1kbzA01 80.70 Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesisDTDP-4-dehydrorhamnose reductaseSalmonella enterica subsp. enterica serovar Typhimurium 3.40.50.720 213 9 81 4.06 5.00
1eq2A01 80.57 Metabolic pathwaysLipopolysaccharide biosynthesisMembraneProtein bindingADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] 3.40.50.720 202 13 79 3.60 4.53
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Displaying entries 1 to 47 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1uzmB00
AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEVDVTDSDAVDRAFTAVEEHQGPVEVLVSN
AGLSAMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSQANYAASKAGVIGMARSIARELSKANVTANVV
APGYIDTALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGM
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1uzmB00
MTATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEVDVTDSDAVDRAFTAVEEHQG
PVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGV
IGMARSIARELSKANVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVD
GGMGMGH
BLAST against CATH

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Domain History Events (16)

Domain assigned by auto on 15 Aug 2007 06:10

Assigning to "3.40.50.720" based on similarity with "2ntnA00"

Flow stage update by auto on 15 Aug 2007 05:59

No in_process hits for Domain "1uzmB00" ready to be processed

Update comment by auto on 15 Aug 2007 05:30

Domain "1uzmB00" hits Domain "1q7cB00" (42.6229508196721% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 05:01

Domain "1uzmB00" hits Domain "1q7cA00" (42.6229508196721% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 04:30

Domain "1uzmB00" hits Domain "1i01D00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 03:55

Domain "1uzmB00" hits Domain "1i01H00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 03:14

Domain "1uzmB00" hits Domain "1i01G00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 02:33

Domain "1uzmB00" hits Domain "1i01F00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 15 Aug 2007 01:22

Domain "1uzmB00" hits Domain "1i01E00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 14 Aug 2007 23:56

Domain "1uzmB00" hits Domain "1i01B00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Update comment by auto on 14 Aug 2007 22:45

Domain "1uzmB00" hits Domain "1i01C00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Flow stage update by auto on 19 Jul 2007 10:57

Domain "1uzmB00" hits Domain "1i01A00" (43.0327868852459% over 95.5465587044534%) which is currently in process

Flow stage update by auto on 19 Jul 2007 10:57

NW result present for Domain "1uzmB00"

Flow stage update by auto on 16 Jul 2007 22:37

All required files are present for Domain "1uzmB00"

Flow stage update by auto on 15 Jul 2007 19:15

Beginning processing for Domain "1uzmB00"

Insertion by auto on 15 Jul 2007 18:13

Final ChopClose added based on similarity with "1i01A"