CATH Domain: 1u1sA00

1u1sA00

PDB 1u1s, Chain A, Domain 0

CATH Code	Level Description	Links
2	Mainly Beta
2.30	Roll
2.30.30	SH3 type barrels.
2.30.30.100		Gene3D
2.30.30.100.2
2.30.30.100.2.1
2.30.30.100.2.1.1
2.30.30.100.2.1.1.1
2.30.30.100.2.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 1u1sA00

Domain	Start PDB Residue	Stop PDB Residue
1u1sA00	6	71

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (13 entries)

There are 13 matching structural neighberhood comparisons for CATH ID 2.30.30.100.2.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1mgqF00	88.32	Methanothermobacter thermautotrophicus str. Delta HSmall nuclear ribonucleoproteinPutative snRNP Sm-like protein	2.30.30.100	70	18	81	1.54	1.89
1b34B00	87.74	SpliceosomeSpliceosomal complexSmall nuclear ribonucleoprotein Sm D2Homo sapiensSmall nuclear ribonucleoprotein D2	2.30.30.100	74	19	89	3.68	4.13
1d3bC00	87.56	SpliceosomeSystemic lupus erythematosusSmall nuclear ribonucleoprotein Sm D3Small nuclear ribonucleoprotein D3Spliceosomal complex	2.30.30.100	71	9	81	1.45	1.77
1m5q101	87.30	Pyrobaculum aerophilumSmall nuclear ribonucleoprotein homolog (Sm-like)	2.30.30.100	67	21	85	1.63	1.92
1n9rB00	87.09	Protein bindingNuclear mRNA splicing, via spliceosomeSmall nuclear ribonucleoprotein FSmall nuclear ribonucleoprotein FU5 snRNP	2.30.30.100	69	12	79	2.01	2.52
1ljoA00	86.05	Archaeoglobus fulgidusSnRNP, putative	2.30.30.100	75	12	77	1.60	2.07
1b34A00	85.64	SpliceosomeSystemic lupus erythematosusSmall nuclear ribonucleoprotein Sm D1RNA bindingProtein binding	2.30.30.100	80	21	78	1.75	2.22
1d3bB00	84.35	Small nuclear ribonucleoprotein-associated proteins B and B'Spliceosomal complexU7 snRNPHomo sapiensProtein binding	2.30.30.100	81	10	71	3.18	4.44
1ib8A02	84.18	Hypothetical proteinRibosome maturation factor rimPStreptococcus pneumoniae	2.30.30.180	67	6	86	2.56	2.96
2k57A00	83.90	Pseudomonas syringae pv. phaseolicola 1448ALipoprotein, putative	2.30.30.100	55	18	75	1.98	2.61
1biaA03	81.32	Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity	2.30.30.100	47	14	68	1.81	2.65
1sf9A02	78.40	Bacillus subtilisUncharacterized protein yfhH	2.30.30.340	54	5	74	3.10	4.18
1mmdA01	76.47	ActomyosinMyosin II complexActin-myosin filament slidingProtein localizationActin filament binding	2.30.30.360	48	14	62	3.03	4.88

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Domain ATOM Sequence

>pdb|1u1sA00
SLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLP

BLAST against CATH

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Domain COMBS Sequence

>pdb|1u1sA00
MSKGHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLPSGDQPAEPG
NA

BLAST against CATH

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Domain History Events (13)

Domain assigned by auto on 02 Nov 2006 03:27

Assigning to "2.30.30.100" based on similarity with "1u1sE00"

Flow stage update by auto on 02 Nov 2006 03:16

No in_process hits for Domain "1u1sA00" ready to be processed

Update comment by auto on 01 Nov 2006 21:56

Domain "1u1sA00" hits Domain "1u1tB00" (100% over 100%) which is currently in process