CATH Domain: 1svhA02 XML data for domain: 1svhA02

Molscript image for 1svhA02
1svhA02
PDB coordinates for domain 1svhA02

PDB 1svh, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.200 Phosphorylase Kinase; domain 1
3.30.200.20 Phosphorylase Kinase; domain 1 Gene3D
3.30.200.20.51
3.30.200.20.51.1
3.30.200.20.51.1.2
3.30.200.20.51.1.2.60
3.30.200.20.51.1.2.60.1

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Segment boundaries for domain 1svhA02

Chopping figure for domain 1svhA02
DomainStart PDB ResidueStop PDB Residue
1svhA01 15 32
1svhA01 127 317
1svhA02 33 126
1svhA02 318 348

Structural Neighbourhood (24 entries)

There are 24 matching structural neighberhood comparisons for CATH ID 3.30.200.20.51.1.2.60.1 (SIMAX score < 5)

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Displaying entries 1 to 24 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1o6lA02 91.22 Jak-STAT signaling pathwayRAC-beta serine/threonine-protein kinaseNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.200.20 117 37 90 1.43 1.58
2jedB01 88.41 Protein kinase C theta typeProtein bindingT cell receptor signaling pathwayNovel protein kinase C [EC:2.7.11.13]Adipocytokine signaling pathway 3.30.200.20 125 27 82 2.04 2.48
3a8xB01 87.70 Tight junctionInsulin signaling pathwayEndocytosisVesicle-mediated transportProtein binding 3.30.200.20 130 33 91 3.23 3.53
2acxA02 86.34 G protein-coupled receptor kinase 6Homo sapiensRegulation of G-protein coupled receptor protein signaling pathway 3.30.200.20 91 32 73 1.53 2.08
3d5vA01 83.82 Danio rerioPolo-like kinase 3.30.200.20 92 20 70 3.42 4.87
2jamA01 82.97 Calcium/calmodulin-dependent protein kinase type 1GHomo sapiensCalcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] 3.30.200.20 75 29 60 1.45 2.40
2f2uB01 82.77 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 3.30.200.20 184 34 64 2.88 4.49
1kobA01 82.55 Aplysia californicaTwitchin-like protein 3.30.200.20 109 18 70 2.49 3.51
2dylA01 82.40 Mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]MAP kinase kinase activityNeurotrophin signaling pathwayStress-activated MAPK cascadeT cell receptor signaling pathway 3.30.200.20 91 13 66 1.88 2.84
2zv2A01 82.06 Calcium ion bindingRegulation of protein kinase activityPositive regulation of transcriptionMAPKKK cascadeCytoplasm 3.30.200.20 77 35 60 2.18 3.60
2clqA01 81.99 Induction of apoptosis by extracellular signalsProtein homodimerization activityMitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]Neurotrophin signaling pathwayATP binding 3.30.200.20 85 18 62 1.61 2.56
2evaA01 81.65 Positive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionMitogen-activated protein kinase kinase kinase 7Protein binding 3.30.200.20 82 25 66 1.77 2.68
2ac3A01 81.09 MAP kinase-interacting serine/threonine-protein kinase 2ATP bindingProtein phosphorylationHomo sapiensProtein serine/threonine kinase activity 3.30.200.20 80 22 62 1.80 2.86
3blhA01 80.92 Transcription elongation from RNA polymerase II promoterCyclin-dependent protein kinase activityRNA polymerase II carboxy-terminal domain kinase activityProtein bindingCell proliferation 3.30.200.20 86 22 68 3.19 4.65
3h9rA01 80.86 Positive regulation of osteoblast differentiationBMP signaling pathwayActivin bindingNegative regulation of apoptosisNegative regulation of activin receptor signaling pathway 3.30.200.20 113 12 67 2.42 3.57
3comB01 80.60 Transcription factor bindingPathways in cancerNon-small cell lung cancerCytoplasmSerine/threonine-protein kinase 4 3.30.200.20 85 30 65 3.06 4.68
3bceA01 80.15 Receptor tyrosine-protein kinase erbB-4Transmembrane receptor protein tyrosine kinase activityHomo sapiensBasolateral plasma membraneProtein binding 3.30.200.20 94 21 68 2.33 3.40
3c4cA01 78.98 Neurotrophin signaling pathwayNon-small cell lung cancerCytoplasmErbB signaling pathwayProtein phosphorylation 3.30.200.20 86 17 69 3.34 4.82
2w5aA01 78.53 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1]Regulation of mitosisSerine/threonine-protein kinase Nek2CentrosomeCentrosome separation 3.30.200.20 64 29 50 1.59 3.18
1fvrA01 78.50 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 86 18 66 2.93 4.43
2qkwB01 78.19 Solanum pimpinellifoliumProtein kinaseProtein binding 3.30.200.20 72 23 58 1.78 3.07
1ckiA01 77.56 SpindleRattus norvegicusHedgehog signaling pathwaySoluble fractionCircadian rhythm - mammal 3.30.200.20 64 23 50 1.71 3.37
3g0eA01 77.45 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Protein bindingAcute myeloid leukemia 3.30.200.20 131 12 67 2.82 4.15
2oo8X01 75.37 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 3.30.200.20 60 18 47 2.27 4.77
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Displaying entries 1 to 24 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1svhA02
PAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD
NSNLYMVMEYVPGGFKGPGDTSNFDDYEEEEIRVINEKCGKEFS
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1svhA02
PAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKD
NSNLYMVMEYVPGGFKGPGDTSNFDDYEEEEIRVXINEKCGKEFS
BLAST against CATH

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Domain History Events (5)

Domain assigned by auto on 28 Apr 2006 19:07

Assigning to "3.30.200.20" based on similarity with "1q8tA02" (NWSI: 99.2125984251968, NWO: 100, SPS: 97.92, SPO: 100, RMSD: 0.35)

Flow stage update by auto on 28 Apr 2006 17:50

NW result present for Domain "1svhA02"

Flow stage update by auto on 28 Apr 2006 17:45

All required files are present for Domain "1svhA02"

Flow stage update by auto on 27 Apr 2006 17:31

Beginning processing for Domain "1svhA02"

Insertion by auto on 09 Mar 2006 05:20

Final ChopClose added based on similarity with "1q8tA" [LEE: 0, LME: 0, MR: 3, LG: 3, SS: 96.76, SI: 99.1428571428571, SO: 100]