CATH Domain: 1smoB00 XML data for domain: 1smoB00

Molscript image for 1smoB00
1smoB00
PDB coordinates for domain 1smoB00

PDB 1smo, Chain B, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.20
2.60.40.10.20.1
2.60.40.10.20.1.1
2.60.40.10.20.1.1.1
2.60.40.10.20.1.1.1.1

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Segment boundaries for domain 1smoB00

Chopping figure for domain 1smoB00
DomainStart PDB ResidueStop PDB Residue
1smoB00 26 135

Structural Neighbourhood (99 entries)

There are 99 matching structural neighberhood comparisons for CATH ID 2.60.40.10.20.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 99 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1hkfA00 88.67 Integral to plasma membraneNatural cytotoxicity triggering receptor 2Cellular defense responseNatural killer cell mediated cytotoxicitySignal transduction 2.60.40.10 108 28 96 2.27 2.36
2q87C00 87.85 Homo sapiensCMRF35-like molecule 8CD300 antigen 2.60.40.10 106 20 94 3.22 3.41
3bp6A00 87.76 Mus musculusExternal side of plasma membraneProgrammed cell death protein 1Programmed cell death protein 1T cell receptor signaling pathway 2.60.40.10 111 14 91 2.76 3.00
1u3hA00 87.50 Mus musculusTRAV14-3 2.60.40.10 110 20 94 2.53 2.68
2ialA01 87.05 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 108 16 92 3.24 3.49
2ak4D01 87.00 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 114 14 92 2.75 2.96
2q8bH01 86.21 2.60.40.10 112 12 90 2.82 3.13
1lp9E01 86.03 2.60.40.10 113 18 92 2.67 2.90
2vxtH01 85.94 2.60.40.10 113 13 90 3.06 3.39
1pewA00 85.84 Ig lambda chain V-VI region SUTHomo sapiens 2.60.40.10 108 16 88 2.81 3.19
1t2jA00 85.78 Homo sapiensSingle chain Fv 2.60.40.10 116 16 90 3.07 3.39
1kgcD01 85.76 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 111 11 92 2.62 2.82
1yc7A00 85.21 2.60.40.10 116 16 89 3.43 3.83
1kgcE01 84.66 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 112 20 90 3.20 3.55
2otuA00 84.48 2.60.40.10 115 12 86 3.00 3.45
1oaqL00 84.48 2.60.40.10 110 13 89 3.39 3.81
2ij0C00 84.40 Homo sapiensT cell receptor beta variable 20/OR9-2 2.60.40.10 118 12 85 2.84 3.32
1tvdA00 84.39 Homo sapiensHDV103S1 2.60.40.10 116 15 88 3.01 3.39
2ny1B01 84.28 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 98 19 82 2.29 2.77
1hxmB01 84.14 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 125 13 84 3.37 4.01
1x9qA01 84.07 2.60.40.10 111 12 84 3.03 3.58
2rikA02 84.05 TitinOryctolagus cuniculus 2.60.40.10 95 16 78 2.75 3.52
1ncwH01 84.04 2.60.40.10 119 13 88 2.98 3.38
1xauA00 83.72 Integral to plasma membraneReceptor activityNegative regulation of B cell proliferationProtein bindingMus musculus 2.60.40.10 104 9 84 2.73 3.23
2v44A01 83.70 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 17 78 2.86 3.66
1mfaH01 83.56 2.60.40.10 97 13 78 3.10 3.97
1ypzF01 83.54 2.60.40.10 123 13 85 2.47 2.89
1neuA00 83.18 Rattus norvegicusMyelin protein P0 2.60.40.10 115 11 86 2.84 3.27
1fo0B00 83.10 2.60.40.10 112 10 88 2.67 3.02
1rhfA01 83.09 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 89 13 76 2.84 3.72
1hxmA01 83.09 2.60.40.10 121 10 84 3.15 3.74
1ncnA00 83.04 T-lymphocyte activation antigen CD86Positive regulation of cell proliferationHomo sapiensImmune responseProtein binding 2.60.40.10 110 20 90 3.59 3.99
1waaC00 82.98 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 11 73 2.19 2.97
1dqtA00 82.95 Mus musculusExternal side of plasma membraneCytotoxic T-lymphocyte protein 4 2.60.40.10 117 9 90 3.53 3.90
1nezH00 82.92 T-cell surface glycoprotein CD8 alpha chainProtein homodimerization activityHematopoietic cell lineageCD8A antigen, alpha polypeptideT cell receptor signaling pathway 2.60.40.10 120 10 83 3.16 3.79
2hp4A00 82.90 T-cell surface glycoprotein CD8 alpha chainCD8A antigen, alpha polypeptideHematopoietic cell lineagePrimary immunodeficiencyHomo sapiens 2.60.40.10 112 10 87 3.34 3.82
1eajB00 82.86 Integral to plasma membraneReceptor activityCoxsackievirus and adenovirus receptorViral myocarditisCoxsackievirus and adenovirus receptor 2.60.40.10 120 22 85 3.58 4.21
2aepL01 82.73 2.60.40.10 119 15 80 3.00 3.72
2j8hA01 82.70 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 10 80 3.08 3.85
2j8hA02 82.56 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 11 78 3.18 4.07
2dm2A00 82.49 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 12 80 3.41 4.26
2rikA01 82.46 TitinOryctolagus cuniculus 2.60.40.10 96 14 78 2.97 3.80
1cczA01 82.39 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 93 11 80 2.70 3.38
2a38B01 82.31 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 10 78 3.07 3.93
1iilG02 82.30 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 107 12 77 3.63 4.70
1dr9A01 82.19 Type I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 105 14 87 3.72 4.26
1g1cA00 82.18 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 10 79 2.99 3.78
1fhgA00 82.05 TelokinMeleagris gallopavo 2.60.40.10 102 10 79 3.05 3.86
1cs6A04 81.99 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 23 74 3.21 4.31
2bk8A00 81.94 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 14 79 3.11 3.93
2qsqB01 81.93 Carcinoembryonic antigen-related cell adhesion molecule 5Integral to plasma membraneHomo sapiensBasolateral plasma membrane 2.60.40.10 108 10 89 4.12 4.62
2cqvA00 81.72 Myosin light chain kinase activityProtein phosphorylationHomo sapiensMyosin light chain kinase, smooth muscle 2.60.40.10 114 10 75 3.26 4.32
2c5dC01 81.65 Integral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiensTyrosine-protein kinase receptor UFOSignal transduction 2.60.40.10 104 12 79 2.52 3.19
1olzA03 81.59 Anti-apoptosisReceptor bindingSemaphorin-4DReceptor activityCell adhesion 2.60.40.10 89 20 77 2.83 3.66
2rikA03 81.57 TitinOryctolagus cuniculus 2.60.40.10 92 14 78 3.11 3.98
1uctA01 81.53 Immunoglobulin alpha Fc receptorIntegral to plasma membraneCD89 antigenHomo sapiensImmune response 2.60.40.10 91 13 75 3.03 4.02
1gl4B00 81.48 Chondrocyte differentiationCardiac muscle tissue developmentCartilage development involved in endochondral bone morphogenesisProtein localizationBrain development 2.60.40.10 89 14 73 3.34 4.54
2v44A02 81.25 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 93 16 77 3.23 4.18
2ec8A03 81.16 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 14 77 3.44 4.45
1koaA03 81.09 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 13 78 2.99 3.82
1bihA04 81.08 Hyalophora cecropiaHemolin 2.60.40.10 88 19 71 3.36 4.68
1hzhH01 80.96 2.60.40.10 119 8 75 3.06 4.05
3b43A02 80.94 TitinOryctolagus cuniculus 2.60.40.10 97 11 77 3.14 4.06
1f97A01 80.77 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 102 13 82 3.42 4.13
1cs6A01 80.76 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 105 11 80 2.94 3.63
1pkoA00 80.64 Rattus norvegicusMyelin-oligodendrocyte glycoproteinPositive regulation of MyD88-dependent toll-like receptor signaling pathway 2.60.40.10 123 15 79 2.97 3.73
2gy5A02 80.56 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 2.60.40.10 90 14 75 2.72 3.60
1cs6A02 80.54 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 89 15 71 3.43 4.78
3k3qA00 80.50 2.60.40.10 137 13 78 3.38 4.33
1qz1A03 80.44 Rattus norvegicusPrion diseasesNeural cell adhesion moleculePlasma membraneFibroblast growth factor receptor binding 2.60.40.10 95 15 78 3.38 4.32
1l6zA02 80.41 Mus musculusCarcinoembryonic antigen-related cell adhesion molecule 1 2.60.40.10 96 18 75 3.00 3.98
2ec8A04 80.40 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 12 77 3.28 4.24
1vcaA01 80.36 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationHeterophilic cell-cell adhesionFilopodium 2.60.40.10 89 13 74 3.23 4.33
1i1rA01 80.36 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of osteoblast differentiationPositive regulation of tyrosine phosphorylation of Stat1 protein 2.60.40.10 100 8 78 3.07 3.93
1f97A02 80.22 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 105 9 80 3.95 4.88
1cs6A03 79.95 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 14 76 3.40 4.45
1bihA01 79.53 Hyalophora cecropiaHemolin 2.60.40.10 97 15 79 3.32 4.20
1witA00 79.16 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 93 13 77 3.24 4.19
3bfoA00 79.08 T cell receptor signaling pathwayPositive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionNucleus 2.60.40.10 85 14 68 3.18 4.66
2e9wA01 78.91 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaExtracellular space 2.60.40.10 84 11 64 2.99 4.63
1fltX00 78.82 Vascular endothelial growth factor receptor 1Integral to plasma membraneGrowth factor bindingVascular endothelial growth factor receptor activityFemale pregnancy 2.60.40.10 95 16 76 3.43 4.49
1bihA02 78.78 Hyalophora cecropiaHemolin 2.60.40.10 106 12 80 3.41 4.21
2ec8A01 78.73 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 92 11 64 3.02 4.68
1nkrA02 78.66 Receptor activityIntegral to plasma membraneHomo sapiensImmune responseNatural killer cell inhibitory signaling pathway 2.60.40.10 98 11 75 3.61 4.78
1nkrA01 78.58 Integral to plasma membraneReceptor activityHomo sapiensNatural killer cell inhibitory signaling pathwayImmune response 2.60.40.10 97 11 78 3.86 4.94
1pd6A00 78.56 Myosin-binding protein C, cardiac-typeHomo sapiensVentricular cardiac muscle tissue morphogenesisStriated muscle myosin thick filamentStructural constituent of muscle 2.60.40.10 94 13 74 2.70 3.62
1nctA00 78.09 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 15 78 3.48 4.45
1iamA02 77.89 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 102 6 77 3.21 4.15
2fcbA01 77.75 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 86 16 64 3.14 4.86
1itbB01 77.63 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 92 18 78 3.75 4.80
3d85D01 77.53 2.60.40.10 84 15 65 2.45 3.74
1f3rB02 77.34 2.60.40.10 99 14 65 2.68 4.09
1p53A01 77.32 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 98 8 75 3.31 4.39
2gy5A04 76.99 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 9 78 3.56 4.55
1cwvA02 76.90 InvasinYersinia pseudotuberculosis 2.60.40.920 97 6 73 3.60 4.89
1clcA01 75.46 Clostridium thermocellumEndoglucanase D 2.60.40.10 102 3 64 2.72 4.21
1kv3A01 75.29 Huntington's diseaseProtein-glutamine gamma-glutamyltransferase 2Homo sapiensTransglutaminase 2 [EC:2.3.2.13] 2.60.40.10 111 9 74 3.68 4.92
1gsmA02 75.24 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 116 8 73 3.52 4.80
3cmgA04 74.69 Putative beta-galactosidaseBacteroides fragilis NCTC 9343 2.60.40.1560 87 9 70 3.14 4.49
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Displaying entries 1 to 99 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1smoB00
EEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRMVNLQV
EDSGLYQCVIYQPPKEPHMLFDRIRLVVTK
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1smoB00
ATKLTEEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRM
VNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSG
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:38

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:38

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:58

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"