CATH Domain: 1rg8A00 XML data for domain: 1rg8A00

Molscript image for 1rg8A00
1rg8A00
PDB coordinates for domain 1rg8A00

PDB 1rg8, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.80 Trefoil
2.80.10 Trefoil (Acidic Fibroblast Growth Factor, subunit A)
2.80.10.50 Gene3D
2.80.10.50.1
2.80.10.50.1.1
2.80.10.50.1.1.1
2.80.10.50.1.1.1.1
2.80.10.50.1.1.1.1.1

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Segment boundaries for domain 1rg8A00

Chopping figure for domain 1rg8A00
DomainStart PDB ResidueStop PDB Residue
1rg8A00 -3 137

Structural Neighbourhood (31 entries)

There are 31 matching structural neighberhood comparisons for CATH ID 2.80.10.50.1.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 31 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1q1uA00 90.81 Pathways in cancerMAPK signaling pathwayMelanomaRegulation of actin cytoskeletonFibroblast growth factor 12 2.80.10.50 138 31 93 2.92 3.12
2fdbN00 89.73 Type 2 fibroblast growth factor receptor bindingMesonephros developmentPositive regulation of cell proliferationType 1 fibroblast growth factor receptor bindingExtracellular space 2.80.10.50 148 19 93 4.60 4.90
1pwaA00 86.72 Negative regulation of bile acid biosynthetic processNervous system developmentPositive regulation of glucose importPathways in cancerPositive regulation of cell proliferation 2.80.10.50 123 31 79 1.67 2.10
1upsA02 85.46 Clostridium perfringensGlcNAc-alpha-1,4-Gal-releasing endo-beta-galactosidase 2.80.10.50 133 14 88 2.07 2.33
1n4kA01 85.05 MicrosomeVoluntary musculoskeletal movementNucleolusPhosphoinositide bindingSarcoplasmic reticulum 2.80.10.50 141 12 83 2.14 2.56
1dfcA03 84.95 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 17 85 2.64 3.10
1ybiA01 84.67 HA-33Clostridium botulinum 2.80.10.50 143 12 88 1.99 2.24
1l2hA00 84.60 Prion diseasesPositive regulation of nitric oxide biosynthetic processType I diabetes mellitusPositive regulation of T cell proliferationAlzheimer's disease 2.80.10.50 144 11 84 2.40 2.86
1ybiA02 84.41 HA-33Clostridium botulinum 2.80.10.50 141 6 87 2.03 2.31
1w3fA01 83.91 Laetiporus sulphureusHemolytic lectin LSLa 2.80.10.50 147 9 89 2.68 2.98
1vclA02 83.56 Cucumaria echinataHemolytic lectin CEL-III 2.80.10.50 134 8 86 2.29 2.65
1jlxA02 83.31 Amaranthus caudatusAgglutinin 2.80.10.50 140 12 88 2.52 2.84
2vxtI00 83.12 Cytokine activityInterleukin 18Signal transducer activityInterleukin-18Interferon-gamma biosynthetic process 2.80.10.50 156 10 83 4.04 4.81
1wd3A02 83.04 Alpha-L-arabinofuranosidase BAspergillus awamori 2.80.10.50 162 9 82 2.53 3.08
1m2tB02 82.64 Beta-galactoside-specific lectin 1Viscum album 2.80.10.50 124 10 80 2.16 2.70
3c9zA02 82.50 Sambucus nigraNigrin b 2.80.10.50 125 8 80 2.12 2.62
1dfcA02 82.50 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 6 83 2.36 2.82
1t9fA00 81.94 Caenorhabditis elegansPutative uncharacterized protein 2.80.10.50 178 8 74 2.97 4.00
3c9zA01 81.85 Sambucus nigraNigrin b 2.80.10.50 130 3 81 2.30 2.82
1jlxA01 81.57 Amaranthus caudatusAgglutinin 2.80.10.50 159 14 81 2.64 3.25
1knmA00 81.25 Streptomyces lividansEndo-1,4-beta-xylanase A 2.80.10.50 129 4 82 3.00 3.62
1md6A00 81.14 Mus musculusInterleukin-1 family member 5Interleukin 1 family, member 5 (delta) 2.80.10.50 154 9 80 3.30 4.10
1dfcA01 81.03 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 122 17 81 2.13 2.61
1dfcA04 79.89 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 107 18 75 2.20 2.93
1hcdA00 79.37 Membrane fractionPlasma membraneActin filament bindingHisactophilin-1Cytosol 2.80.10.50 118 14 81 2.84 3.48
2qn4A00 78.78 Oryza sativa Japonica GroupAlpha-amylase inhibitor activityAlpha-amylase/subtilisin inhibitorSerine-type endopeptidase inhibitor activity 2.80.10.50 159 7 79 3.48 4.36
1wbaA00 77.40 Psophocarpus tetragonolobusAlbumin-1 2.80.10.50 171 7 76 3.71 4.84
1avwB00 77.05 Glycine maxTrypsin inhibitor A 2.80.10.50 171 7 75 3.46 4.59
1xzzA00 76.79 MicrosomeNucleolusPhosphoinositide bindingVoluntary musculoskeletal movementSarcoplasmic reticulum 2.80.10.50 216 7 57 2.50 4.32
1epwA04 76.57 Bontoxilysin [EC:3.4.24.69]Clostridium botulinumBotulinum neurotoxin type B 2.80.10.50 191 5 67 2.73 4.07
1r8nA00 76.14 Kunitz-type serine protease inhibitor DrTIDelonix regiaSerine-type endopeptidase inhibitor activity 2.80.10.50 185 8 73 3.47 4.72
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Displaying entries 1 to 31 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1rg8A00
HHHHFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS
QTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1rg8A00
HHHHHHFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLY
GSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:09

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"