CATH Domain: 1r3lB01 XML data for domain: 1r3lB01

Molscript image for 1r3lB01
1r3lB01
PDB coordinates for domain 1r3lB01

PDB 1r3l, Chain B, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.15
2.60.40.10.15.1
2.60.40.10.15.1.3
2.60.40.10.15.1.3.1
2.60.40.10.15.1.3.1.14

Segment boundaries for domain 1r3lB01

Chopping figure for domain 1r3lB01
DomainStart PDB ResidueStop PDB Residue
1r3lB01 1 118
1r3lB02 119 217

Structural Neighbourhood (197 entries)

There are 197 matching structural neighberhood comparisons for CATH ID 2.60.40.10.15.1.3.1.14 (SIMAX score < 5)

Displaying entries 1 to 197 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2vxtH01 94.84 2.60.40.10 113 69 97 1.33 1.37
2q8bH01 93.53 2.60.40.10 112 62 96 1.04 1.08
1mfaH01 91.64 2.60.40.10 97 71 83 0.91 1.09
1yc7A00 91.25 2.60.40.10 116 38 97 1.95 2.00
1ncwH01 91.14 2.60.40.10 119 49 95 1.57 1.64
1t2jA00 90.54 Homo sapiensSingle chain Fv 2.60.40.10 116 46 99 2.51 2.53
1hxmB01 90.53 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 125 20 91 1.38 1.51
2otuA00 90.14 2.60.40.10 115 23 94 1.50 1.58
2ak4D01 89.86 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 114 21 95 2.24 2.34
1pewA00 89.75 Ig lambda chain V-VI region SUTHomo sapiens 2.60.40.10 108 25 93 1.43 1.54
1oaqL00 89.62 2.60.40.10 110 21 93 1.79 1.91
2ij0C00 89.22 Homo sapiensT cell receptor beta variable 20/OR9-2 2.60.40.10 118 24 93 1.80 1.93
1hxmA01 89.20 2.60.40.10 121 25 90 1.46 1.61
1kgcE01 89.18 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 112 24 93 2.01 2.14
1x9qA01 89.13 2.60.40.10 111 17 90 1.71 1.89
1tvdA00 88.80 Homo sapiensHDV103S1 2.60.40.10 116 22 96 1.73 1.79
1kgcD01 88.74 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 111 27 92 2.07 2.25
1nezH00 88.70 T-cell surface glycoprotein CD8 alpha chainProtein homodimerization activityHematopoietic cell lineageCD8A antigen, alpha polypeptideT cell receptor signaling pathway 2.60.40.10 120 14 91 1.81 1.97
1neuA00 88.68 Rattus norvegicusMyelin protein P0 2.60.40.10 115 15 95 1.95 2.04
1ogaE01 88.55 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 111 24 93 2.03 2.16
1hzhH01 88.52 2.60.40.10 119 40 78 1.34 1.71
2aepL01 88.50 2.60.40.10 119 18 89 1.80 2.02
2ialA01 88.42 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 108 24 91 2.00 2.19
3bp6A00 88.05 Mus musculusExternal side of plasma membraneProgrammed cell death protein 1Programmed cell death protein 1T cell receptor signaling pathway 2.60.40.10 111 16 93 1.91 2.03
2hp4A00 87.97 T-cell surface glycoprotein CD8 alpha chainCD8A antigen, alpha polypeptideHematopoietic cell lineagePrimary immunodeficiencyHomo sapiens 2.60.40.10 112 13 93 1.94 2.07
1u3hA00 87.87 Mus musculusTRAV14-3 2.60.40.10 110 23 93 1.89 2.03
1lp9E01 87.55 2.60.40.10 113 24 93 2.03 2.16
1ypzF01 87.23 2.60.40.10 123 26 91 2.21 2.41
1fo0B00 86.54 2.60.40.10 112 19 93 2.74 2.94
1qfoC00 86.47 Mus musculusSialoadhesinProtein binding 2.60.40.10 114 15 96 3.65 3.78
3k3qA00 86.06 2.60.40.10 137 35 83 2.00 2.38
2v44A01 85.78 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 13 78 1.80 2.30
1dqtA00 85.49 Mus musculusExternal side of plasma membraneCytotoxic T-lymphocyte protein 4 2.60.40.10 117 16 94 3.01 3.20
2j8hA01 85.35 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 17 80 2.14 2.65
2ny1B01 85.33 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 98 18 83 2.34 2.80
1pkoA00 85.32 Rattus norvegicusMyelin-oligodendrocyte glycoproteinPositive regulation of MyD88-dependent toll-like receptor signaling pathway 2.60.40.10 123 9 86 2.14 2.46
1f97A01 85.31 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 102 20 86 2.04 2.37
1smoB00 85.30 Receptor activityTriggering receptor expressed on myeloid cells 1Homo sapiensHumoral immune response 2.60.40.10 110 14 91 2.85 3.12
2rikA02 85.25 TitinOryctolagus cuniculus 2.60.40.10 95 18 79 1.99 2.51
2bk8A00 85.19 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 16 80 2.07 2.59
1eajB00 85.19 Integral to plasma membraneReceptor activityCoxsackievirus and adenovirus receptorViral myocarditisCoxsackievirus and adenovirus receptor 2.60.40.10 120 15 93 2.88 3.09
2q87C00 84.92 Homo sapiensCMRF35-like molecule 8CD300 antigen 2.60.40.10 106 14 87 3.59 4.09
2qsqB01 84.74 Carcinoembryonic antigen-related cell adhesion molecule 5Integral to plasma membraneHomo sapiensBasolateral plasma membrane 2.60.40.10 108 12 93 3.40 3.65
1xauA00 84.71 Integral to plasma membraneReceptor activityNegative regulation of B cell proliferationProtein bindingMus musculus 2.60.40.10 104 12 85 1.95 2.29
1qz1A03 84.66 Rattus norvegicusPrion diseasesNeural cell adhesion moleculePlasma membraneFibroblast growth factor receptor binding 2.60.40.10 95 21 79 2.76 3.49
2j8hA02 84.57 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 17 79 2.19 2.77
1ncnA00 84.41 T-lymphocyte activation antigen CD86Positive regulation of cell proliferationHomo sapiensImmune responseProtein binding 2.60.40.10 110 14 86 2.04 2.35
1dr9A01 84.36 Type I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 105 13 86 2.91 3.38
1cczA01 84.31 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 93 16 80 2.63 3.25
2g5rA00 84.17 Sialic acid-binding Ig-like lectin 7Sialic acid binding Ig-like lectin 7Receptor activityIntegral to plasma membraneHomo sapiens 2.60.40.10 113 13 93 3.36 3.61
2rikA03 84.16 TitinOryctolagus cuniculus 2.60.40.10 92 19 79 2.19 2.77
1hkfA00 84.11 Integral to plasma membraneNatural cytotoxicity triggering receptor 2Cellular defense responseNatural killer cell mediated cytotoxicitySignal transduction 2.60.40.10 108 12 92 3.21 3.48
2a38B01 83.86 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 14 80 2.05 2.53
1fhgA00 83.81 TelokinMeleagris gallopavo 2.60.40.10 102 15 80 2.23 2.79
2rikA01 83.71 TitinOryctolagus cuniculus 2.60.40.10 96 17 79 1.91 2.41
1g1cA00 83.66 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 12 80 2.16 2.70
2dm2A00 83.60 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 15 80 2.49 3.08
1olzA03 83.53 Anti-apoptosisReceptor bindingSemaphorin-4DReceptor activityCell adhesion 2.60.40.10 89 16 73 2.06 2.79
3cafA01 83.35 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 96 14 79 2.41 3.05
1vcaA01 83.35 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationHeterophilic cell-cell adhesionFilopodium 2.60.40.10 89 16 75 2.14 2.83
1bihA04 83.21 Hyalophora cecropiaHemolin 2.60.40.10 88 20 73 2.19 2.96
1i1rA01 83.08 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of osteoblast differentiationPositive regulation of tyrosine phosphorylation of Stat1 protein 2.60.40.10 100 8 78 2.31 2.95
1iilG02 83.07 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 107 14 78 3.20 4.09
1rhfA01 83.06 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 89 23 74 3.05 4.08
2cqvA00 83.00 Myosin light chain kinase activityProtein phosphorylationHomo sapiensMyosin light chain kinase, smooth muscle 2.60.40.10 114 14 79 2.18 2.75
1waaC00 82.86 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 7 74 1.87 2.50
1l6zA02 82.79 Mus musculusCarcinoembryonic antigen-related cell adhesion molecule 1 2.60.40.10 96 14 77 2.28 2.95
1gl4B00 82.78 Chondrocyte differentiationCardiac muscle tissue developmentCartilage development involved in endochondral bone morphogenesisProtein localizationBrain development 2.60.40.10 89 16 74 2.13 2.85
2c5dC01 82.66 Integral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiensTyrosine-protein kinase receptor UFOSignal transduction 2.60.40.10 104 16 80 1.91 2.39
1cs6A02 82.63 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 89 16 73 2.63 3.60
1bihA01 82.48 Hyalophora cecropiaHemolin 2.60.40.10 97 15 79 2.30 2.91
2ec8A04 82.47 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 10 78 2.23 2.85
1cs6A01 82.47 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 105 9 80 2.49 3.08
1koaA03 82.45 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 13 79 2.03 2.57
1f97A02 82.43 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 105 12 83 2.75 3.29
3b43A02 82.41 TitinOryctolagus cuniculus 2.60.40.10 97 13 78 2.08 2.66
2ec8A03 82.34 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 12 78 2.85 3.64
1uctA01 82.28 Immunoglobulin alpha Fc receptorIntegral to plasma membraneCD89 antigenHomo sapiensImmune response 2.60.40.10 91 10 75 2.77 3.66
1itbB03 82.10 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 112 11 81 2.43 2.97
1cs6A03 82.05 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 15 77 2.60 3.36
1iamA02 82.02 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 102 9 77 2.39 3.09
1zxqA02 82.01 Intercellular adhesion molecule 2Integral to plasma membraneIntercellular adhesion molecule 2Natural killer cell mediated cytotoxicityHomo sapiens 2.60.40.10 107 13 81 3.20 3.91
2gy5A02 81.96 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 2.60.40.10 90 15 76 2.72 3.55
1nkrA01 81.96 Integral to plasma membraneReceptor activityHomo sapiensNatural killer cell inhibitory signaling pathwayImmune response 2.60.40.10 97 13 79 2.89 3.65
1gsmA01 81.79 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 90 13 74 3.06 4.09
1cs6A04 81.61 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 20 75 2.15 2.84
2v44A02 81.52 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 93 13 76 2.11 2.76
2fcbA02 81.28 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 87 13 73 2.65 3.63
1witA00 81.25 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 93 13 78 2.71 3.46
1f2qA02 81.25 High affinity immunoglobulin epsilon receptor subunit alphaIntegral to plasma membraneHomo sapiensFc receptor, IgE, high affinity I, alpha polypeptideAsthma 2.60.40.10 90 23 73 2.88 3.90
1f3rB02 80.88 2.60.40.10 99 18 71 2.46 3.45
1bihA03 80.76 Hyalophora cecropiaHemolin 2.60.40.10 100 15 79 3.12 3.94
1iamA01 80.69 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 15 71 2.95 4.14
3bfoA00 80.58 T cell receptor signaling pathwayPositive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionNucleus 2.60.40.10 85 12 69 2.14 3.08
1nkrA02 80.50 Receptor activityIntegral to plasma membraneHomo sapiensImmune responseNatural killer cell inhibitory signaling pathway 2.60.40.10 98 14 74 2.60 3.48
1g0dA03 80.39 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 110 8 81 3.64 4.45
1fltX00 80.39 Vascular endothelial growth factor receptor 1Integral to plasma membraneGrowth factor bindingVascular endothelial growth factor receptor activityFemale pregnancy 2.60.40.10 95 11 77 3.29 4.25
1pd6A00 80.31 Myosin-binding protein C, cardiac-typeHomo sapiensVentricular cardiac muscle tissue morphogenesisStriated muscle myosin thick filamentStructural constituent of muscle 2.60.40.10 94 17 75 2.66 3.52
1ugnA01 80.29 Homo sapiensLeukocyte immunoglobulin-like receptor subfamily B member 1Integral to membraneResponse to virusProtein phosphatase 1 binding 2.60.40.10 95 9 72 3.31 4.59
2ec8A01 80.28 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 92 11 66 2.22 3.36
2ifgA02 80.11 High affinity nerve growth factor receptorIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiens 2.60.40.10 90 16 74 3.22 4.31
1t0pB00 80.09 Integral to plasma membraneIntercellular adhesion molecule 3Homo sapiensIntercellular adhesion molecule 3Cell adhesion molecules (CAMs) 2.60.40.10 86 16 71 2.50 3.51
1p53A01 80.06 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 98 16 76 2.70 3.53
1ej6A05 80.02 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 10 80 3.20 3.96
1n26A02 80.00 Positive regulation of chemokine productionPositive regulation of smooth muscle cell proliferationJak-STAT signaling pathwayAcute-phase responsePositive regulation of osteoblast differentiation 2.60.40.10 78 21 66 2.93 4.43
2gy5A01 79.96 Cell surfaceMicrovillusIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transduction 2.60.40.10 99 13 80 3.28 4.06
2e9wA01 79.94 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaExtracellular space 2.60.40.10 84 13 66 2.22 3.36
1rhfA02 79.80 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 84 21 71 2.48 3.48
1q0xL02 79.78 Mus musculusIg lambda-1 chain V regionProtein binding 2.60.40.10 100 10 74 2.95 3.94
1bihA02 79.65 Hyalophora cecropiaHemolin 2.60.40.10 106 14 80 2.96 3.66
1cidA01 79.57 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 106 7 87 3.90 4.44
1f6fB01 79.45 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 4 80 3.85 4.81
2gy5A04 79.41 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 18 76 3.30 4.31
1edqA01 79.38 Chitinase ASerratia marcescens 2.60.40.10 107 5 73 2.95 3.99
1ow0A02 79.37 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 109 7 76 3.21 4.19
1o0vA01 79.37 Homo sapiensIg epsilon chain C region 2.60.40.10 102 15 77 3.44 4.44
3h9yA02 79.36 Homo sapiensIg epsilon chain C region 2.60.40.10 108 6 75 3.23 4.27
2fcbA01 79.30 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 86 16 69 2.99 4.30
3b4nA01 79.11 Erwinia chrysanthemiEndo-pectate lyase 2.60.40.10 88 7 73 2.87 3.88
1uvqA02 78.85 2.60.40.10 99 10 73 3.14 4.30
2bc4A02 78.83 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 9 76 3.50 4.57
1kv3A03 78.54 Huntington's diseaseProtein-glutamine gamma-glutamyltransferase 2Homo sapiensTransglutaminase 2 [EC:2.3.2.13] 2.60.40.10 117 2 82 3.84 4.68
2nqcA00 78.53 Plasma membraneFilamin-CHomo sapiens 2.60.40.10 97 8 73 3.39 4.59
2gysB04 78.53 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 99 7 74 3.16 4.23
3b9eA01 78.50 Vibrio harveyiChitinase A 2.60.40.10 110 4 73 2.96 4.00
1vjjA03 78.50 Calcium ion bindingHair follicle morphogenesisGTP bindingExtrinsic to internal side of plasma membraneTransglutaminase 3 [EC:2.3.2.13] 2.60.40.10 115 6 83 3.92 4.70
1l6xA02 78.45 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 106 7 74 3.28 4.39
3dbxA02 78.32 CD1-2 antigenGallus gallus 2.60.40.10 99 11 73 3.63 4.97
1l6xA01 78.28 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 100 6 73 3.08 4.17
1n26A01 78.22 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 107 4 80 3.26 4.08
1ze3C01 78.13 Fimbrial chaperone proteinChaperone protein fimCEscherichia coli K-12 2.60.40.360 117 4 78 3.36 4.27
1xiwA00 78.11 Chagas diseaseHematopoietic cell lineageReceptor signaling protein activitySH3 domain bindingT cell receptor signaling pathway 2.60.40.10 91 14 73 3.56 4.82
1cwvA03 77.85 InvasinYersinia pseudotuberculosis 2.60.40.920 102 4 76 3.60 4.70
3cmgA04 77.81 Putative beta-galactosidaseBacteroides fragilis NCTC 9343 2.60.40.1560 87 10 69 2.67 3.84
2vxvH02 77.78 2.60.40.10 101 8 73 3.35 4.59
1gsmA02 77.76 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 116 10 77 2.71 3.49
1hxmB02 77.70 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 5 74 3.16 4.23
1qfhA01 77.60 ThermotaxisPhagocytic cupMembrane fractionPhototaxisProtein homodimerization activity 2.60.40.10 111 9 77 3.43 4.43
1ujtA00 77.59 LuteolysisPositive regulation of axonogenesisCell surfaceIdentical protein bindingHomophilic cell adhesion 2.60.40.10 120 7 75 3.34 4.45
1dn0D02 77.56 2.60.40.10 94 12 69 3.13 4.50
2bnuB02 77.54 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 126 7 69 3.42 4.95
1mcpH02 77.47 Mus musculusIg heavy chain V region M603 2.60.40.10 99 9 73 3.59 4.91
2r2cB00 77.34 Porphyromonas gingivalis28 kDa outer membrane protein Omp28 2.60.40.320 107 2 80 3.83 4.79
2q0zX03 77.33 ATP-dependent helicase activityPre-mRNA-splicing helicase BRR2 [EC:3.6.1.-]Protein bindingU5 small nuclear ribonucleoprotein 200 kDa helicaseU5 snRNP 2.60.40.150 113 7 80 3.75 4.69
1ji1A01 77.28 Neopullulanase 1Thermoactinomyces vulgaris 2.60.40.10 124 9 73 3.12 4.25
1seqH02 77.26 Rattus norvegicusIghg protein 2.60.40.10 98 8 73 3.54 4.85
1nctA00 77.25 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 15 79 2.90 3.66
3fruA02 77.20 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 10 68 3.22 4.69
2cumA00 77.17 Collagen metabolic processElastic fiber assemblyIntracellularHomo sapiensTenascin-X 2.60.40.10 105 12 74 2.92 3.90
1y6kR01 77.12 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 102 8 76 3.16 4.13
2ec8A02 77.11 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 87 10 72 3.11 4.31
1ut9A01 77.11 Clostridium thermocellumCellobiohydrolase 2.60.40.10 98 4 73 3.07 4.20
1fnfA02 76.98 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 87 6 73 3.10 4.24
1clcA01 76.90 Clostridium thermocellumEndoglucanase D 2.60.40.10 102 6 66 2.63 3.98
1g0dA01 76.88 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 137 6 76 3.70 4.83
1qg3A01 76.82 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 91 3 73 3.13 4.23
1f00I01 76.77 Pathogenic Escherichia coli infectionIntiminIntiminProtein bindingEscherichia coli O127:H6 str. E2348/69 2.60.40.920 95 8 75 3.42 4.52
3bgaA04 76.68 Galactose metabolismBacteroides thetaiotaomicronBeta-galactosidaseSphingolipid metabolismBeta-galactosidase [EC:3.2.1.23] 2.60.40.320 105 5 76 3.75 4.90
1itbB01 76.67 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 92 10 79 3.60 4.55
1qg3A02 76.60 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 104 6 80 3.60 4.50
1fnhA03 76.55 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 10 74 3.25 4.35
2gysA02 76.50 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 102 9 78 3.69 4.71
3k2mC00 76.49 2.60.40.10 101 8 76 3.38 4.42
1j0hA01 76.44 NeopullulanaseGeobacillus stearothermophilus 2.60.40.10 125 4 72 3.11 4.27
1cfbA01 76.44 Calcium ion bindingNeuron cell-cell adhesionNerve maturationDrosophila melanogasterEpidermal growth factor receptor signaling pathway 2.60.40.10 99 3 77 3.46 4.47
1bquA01 76.44 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 5 79 3.66 4.63
1f6fB02 76.40 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 8 76 3.52 4.60
3di2B02 76.28 Interleukin-7 receptor activityRegulation of DNA recombinationInterleukin-7 receptor subunit alphaHomo sapiensCell surface receptor linked signaling pathway 2.60.40.10 103 5 79 3.91 4.94
1qr4A01 76.08 TenascinGallus gallus 2.60.40.10 87 6 74 3.00 4.01
1wzlA01 76.00 Neopullulanase 2Thermoactinomyces vulgaris 2.60.40.10 121 3 76 3.44 4.52
1u2cA01 76.00 Epithelial tube branching involved in lung morphogenesisDilated cardiomyopathyECM-receptor interactionHypertrophic cardiomyopathy (HCM)Sarcolemma 2.60.40.10 103 5 77 3.47 4.48
1cd9B02 75.99 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 98 11 78 3.51 4.49
1bquA02 75.98 Jak-STAT signaling pathwayOncostatin-M receptor complexResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 108 8 76 3.58 4.68
2e7hA01 75.83 Cell surfaceOrgan morphogenesisIntegral to plasma membraneEph receptor B4 [EC:2.7.10.1]Homo sapiens 2.60.40.10 89 10 71 3.50 4.91
1fnfA03 75.83 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 8 75 3.41 4.51
1uemA00 75.82 LuteolysisPositive regulation of axonogenesisIdentical protein bindingCell surfaceHomophilic cell adhesion 2.60.40.10 117 7 76 3.74 4.92
2mcmA00 75.79 MacromomycinStreptomyces macromomyceticus 2.60.40.230 112 5 74 3.50 4.68
2hftA01 75.72 Positive regulation of endothelial cell proliferationTissue factorPositive regulation of platelet-derived growth factor receptor signaling pathwayPositive regulation of angiogenesisProtease binding 2.60.40.10 103 5 74 3.08 4.12
2a9dA02 75.70 Sulfite oxidaseGallus gallus 2.60.40.650 123 6 73 3.23 4.41
1l0qA02 75.63 Methanosarcina mazeiORF492 2.60.40.670 90 4 66 2.92 4.36
1cczA02 75.61 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 78 10 65 2.98 4.57
1n26A03 75.56 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 104 4 78 3.63 4.64
1p53A03 75.53 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 16 67 3.14 4.63
1im3D00 75.31 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 4 75 3.73 4.93
1dceA02 75.30 Rattus norvegicusRab geranylgeranyltransferase activityProtein geranylgeranyltransferase type II [EC:2.5.1.60]Geranylgeranyl transferase type-2 subunit alpha 2.60.40.1130 103 7 72 3.03 4.20
1iarB02 75.27 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneReceptor signaling protein activityHematopoietic cell lineage 2.60.40.10 92 6 61 2.92 4.73
1j8kA00 75.23 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 94 8 78 3.57 4.56
3hn3A02 75.22 Beta-glucuronidaseGlycosaminoglycan degradationGlycosaminoglycan catabolic processMetabolic pathwaysStarch and sucrose metabolism 2.60.40.320 103 6 73 3.55 4.86
2jllA04 74.98 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 91 7 73 3.55 4.80
2ny1B02 74.94 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 75 12 63 3.08 4.85
1ok8A04 74.89 Dengue virus 2 Puerto Rico/PR159-S1/1969Genome polyprotein 2.60.40.350 100 3 76 3.77 4.93
1cidA02 74.84 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 71 14 61 3.03 4.91
2dtgE04 74.78 Insulin receptorInsulin receptor complexPhosphoinositide 3-kinase bindingPositive regulation of respiratory burstPositive regulation of nitric oxide biosynthetic process 2.60.40.10 123 5 74 3.28 4.39
1ow0A01 74.75 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 100 5 74 3.63 4.85
2gysA03 74.54 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaApoptosis 2.60.40.10 86 5 66 3.27 4.88
2dbjA01 74.40 Integral to plasma membraneSoluble fractionCell-cell signalingC-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]Protein phosphorylation 2.60.40.10 109 8 73 3.50 4.74
2fnbA00 73.54 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 95 7 77 3.78 4.88
Displaying entries 1 to 197 (page 1 of 1)


Domain ATOM Sequence

>pdb|1r3lB01
QVQLQQPGAELVKPGASVKLSCKASGYTFTSDWIHWVKQRPGHGLEWIGEIIPSYGRANYNEKIQKKATLTADKSSSTAF
MQLSSLTSEDSAVYYCARERGDGYFAVWGAGTTVTVSS    

Domain COMBS Sequence

>pdb|1r3lB01
QVQLQQPGAELVKPGASVKLSCKASGYTFTSDWIHWVKQRPGHGLEWIGEIIPSYGRANYNEKIQKKATLTADKSSSTAF
MQLSSLTSEDSAVYYCARERGDGYFAVWGAGTTVTVSS    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:35

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:35

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"