CATH Domain: 1r2qA00 XML data for domain: 1r2qA00

Molscript image for 1r2qA00
1r2qA00
PDB coordinates for domain 1r2qA00

PDB 1r2q, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.300 P-loop containing nucleotide triphosphate hydrolases Gene3D
3.40.50.300.17
3.40.50.300.17.1
3.40.50.300.17.1.1
3.40.50.300.17.1.1.1
3.40.50.300.17.1.1.1.1

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Segment boundaries for domain 1r2qA00

Chopping figure for domain 1r2qA00
DomainStart PDB ResidueStop PDB Residue
1r2qA00 15 184

Structural Neighbourhood (39 entries)

There are 39 matching structural neighberhood comparisons for CATH ID 3.40.50.300.17.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 39 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1z0jA00 95.06 Ras-related protein Rab-22AMus musculusGTPase activityGTP bindingProtein binding 3.40.50.300 169 49 99 1.06 1.07
1x3sA00 91.87 Ras-related protein Rab-18IntracellularHomo sapiens 3.40.50.300 175 41 95 1.75 1.83
2erxA00 91.72 DIRAS family, GTP-binding Ras-like 2Homo sapiensGTP-binding protein Di-Ras2 3.40.50.300 168 32 96 1.97 2.04
1wmsA00 90.39 Ras-related protein Rab-9ALysosomeGTP bindingProtein bindingGDP binding 3.40.50.300 170 36 97 2.09 2.15
1xtqA00 89.99 Insulin signaling pathwayMTOR signaling pathwayGTP-binding protein RhebGTPase activityGTP binding 3.40.50.300 169 28 98 2.12 2.16
2ce2X00 89.94 Neurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathwayTight junction 3.40.50.300 166 28 97 2.13 2.19
3c5cB00 89.59 Ras-like protein family member 12Homo sapiensRas-like, family 12 3.40.50.300 164 25 94 1.88 1.99
2x19A00 89.41 Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Nucleus organizationNucleusNucleocytoplasmic transportProtein binding 3.40.50.300 172 32 96 2.03 2.10
1z2aA00 89.29 Mus musculusRegulation of smoothened signaling pathwaySpinal cord dorsal/ventral patterningRas-related protein Rab-23Negative regulation of proteolysis 3.40.50.300 164 37 96 2.07 2.15
1ukvY00 89.09 GTP-binding protein YPT1Endoplasmic reticulum membraneRab family, otherER to Golgi vesicle-mediated transportProtein binding 3.40.50.300 197 44 86 2.22 2.57
1mh1A00 89.03 MAPK signaling pathwayNatural killer cell mediated cytotoxicityVEGF signaling pathwayFocal adhesionToll-like receptor signaling pathway 3.40.50.300 183 23 91 1.68 1.84
1m7bA00 88.76 Actin cytoskeleton organizationRho-related GTP-binding protein RhoEGTPase activityGTP bindingCell adhesion 3.40.50.300 179 25 91 1.55 1.69
3cbqA00 88.11 Rad and Gem related GTP binding protein 2GTP-binding protein REM 2Homo sapiens 3.40.50.300 169 25 97 4.74 4.88
2h57B00 87.33 ADP-ribosylation factor-like 6ADP-ribosylation factor-like protein 6Homo sapiens 3.40.50.300 164 20 91 2.20 2.40
3ievA01 83.91 GTP-binding protein era homologGTP-binding protein EraAquifex aeolicus 3.40.50.300 175 15 87 3.33 3.81
1f6bB00 83.58 Cricetulus griseusGTP-binding protein SAR1b 3.40.50.300 180 15 85 2.85 3.35
1nrjB00 82.84 SRP-dependent cotranslational protein targeting to membraneGTP bindingSignal recognition particle receptor subunit betaProtein bindingIntegral to endoplasmic reticulum membrane 3.40.50.300 191 12 80 3.15 3.93
3cx8A01 82.72 Rho protein signal transductionIn utero embryonic developmentGTPase activityPlatelet activationRegulation of cell migration 3.40.50.300 193 19 80 3.67 4.54
1cipA01 82.35 Rattus norvegicusGuanine nucleotide-binding protein G(i) subunit alpha-1Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptideChagas diseaseChemokine signaling pathway 3.40.50.300 197 22 78 3.64 4.63
1zunB01 82.18 Selenoamino acid metabolismSulfur metabolismPurine metabolismSulfate adenylate transferase, subunit 1/adenylylsulfate kinaseMetabolic pathways 3.40.50.300 191 18 83 3.62 4.35
1mkyA01 81.32 Thermotoga maritimaGTP-binding proteinGTP-binding protein engA 3.40.50.300 153 18 82 3.82 4.61
1wb1C01 80.80 Methanococcus maripaludisMJ0495-like protein 3.40.50.300 185 15 87 4.27 4.88
1e5dA01 77.61 Desulfovibrio gigasRubredoxin-oxygen oxidoreductase 3.40.50.360 143 11 77 3.60 4.67
1w25B02 76.98 Two-component systemCell cycle - CaulobacterCaulobacter vibrioidesIdentical protein bindingTwo-component system, cell cycle response regulator 3.40.50.2300 143 4 73 3.46 4.71
3cu5B00 76.96 Clostridium phytofermentans ISDgTwo component transcriptional regulator, AraC family 3.40.50.2300 129 5 70 3.31 4.69
1dbwB00 76.94 Sinorhizobium melilotiTranscriptional regulatory protein fixJ 3.40.50.2300 125 8 71 3.36 4.68
2zayA00 76.46 Response regulator receiver proteinDesulfuromonas acetoxidans DSM 684 3.40.50.2300 123 8 70 3.19 4.56
2qxyA00 76.30 Thermotoga maritimaResponse regulatorTwo-component system, unclassified family, response regulator 3.40.50.2300 118 8 67 2.80 4.14
3b2nA00 76.27 Similar to two-component response regulatorStaphylococcus aureus subsp. aureus Mu50 3.40.50.2300 119 13 68 3.34 4.89
2rjnA00 76.20 Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomainNeptuniibacter caesariensis 3.40.50.2300 135 10 72 3.45 4.77
3d7nA00 76.15 Agrobacterium tumefaciens str. C58Flavodoxin, WrbA-like protein 3.40.50.360 153 8 75 3.73 4.92
1ny5A01 75.92 Transcriptional regulator (NtrC family)Two-component system, NtrC family, response regulatorAquifex aeolicus 3.40.50.2300 136 5 71 3.47 4.88
3cnbA00 75.84 DNA-binding response regulator, merR familyColwellia psychrerythraea 34H 3.40.50.2300 124 8 69 3.40 4.90
2jk1A00 75.70 Hydrogenase transcriptional regulatory protein hupR1Rhodobacter capsulatus 3.40.50.2300 138 8 67 3.28 4.89
2qr3A00 75.64 Bacteroides fragilisTwo-component system response regulator 3.40.50.2300 119 8 68 3.24 4.71
2fvyA01 75.46 Bacterial chemotaxisABC transportersMethyl-galactoside transport system substrate-binding proteinD-galactose-binding periplasmic proteinEscherichia coli K-12 3.40.50.2300 147 7 71 3.44 4.83
3gfsC00 75.43 Bacillus subtilisFMN-dependent NADPH-azoreductase 3.40.50.360 169 5 72 3.63 4.98
1zgzA00 75.03 Two-component systemTorCAD operon transcriptional regulatory protein torRTwo-component system, OmpR family, torCAD operon response regulator TorRProtein bindingEscherichia coli K-12 3.40.50.2300 118 9 67 3.27 4.88
1qo0D01 74.27 Pseudomonas aeruginosaAliphatic amidase regulator 3.40.50.2300 127 7 71 3.54 4.97
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Displaying entries 1 to 39 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1r2qA00
GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQ
AAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIF
MAIAKKLPKN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1r2qA00
GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQ
AAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIF
MAIAKKLPKN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 19:13

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 19:13

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:35

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"