CATH Domain: 1pwaA00 XML data for domain: 1pwaA00

Molscript image for 1pwaA00
1pwaA00
PDB coordinates for domain 1pwaA00

PDB 1pwa, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.80 Trefoil
2.80.10 Trefoil (Acidic Fibroblast Growth Factor, subunit A)
2.80.10.50 Gene3D
2.80.10.50.8
2.80.10.50.8.1
2.80.10.50.8.1.1
2.80.10.50.8.1.1.1
2.80.10.50.8.1.1.1.1

Segment boundaries for domain 1pwaA00

Chopping figure for domain 1pwaA00
DomainStart PDB ResidueStop PDB Residue
1pwaA00 41 176

Structural Neighbourhood (24 entries)

There are 24 matching structural neighberhood comparisons for CATH ID 2.80.10.50.8.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 24 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1q1uA00 86.89 Pathways in cancerMAPK signaling pathwayMelanomaRegulation of actin cytoskeletonFibroblast growth factor 12 2.80.10.50 138 26 81 2.04 2.49
2fdbN00 85.92 Type 2 fibroblast growth factor receptor bindingMesonephros developmentPositive regulation of cell proliferationType 1 fibroblast growth factor receptor bindingExtracellular space 2.80.10.50 148 20 76 1.61 2.11
1dfcA03 85.34 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 18 87 2.12 2.41
1ihkA00 84.96 Pathways in cancerMelanomaMAPK signaling pathwayRegulation of actin cytoskeletonGlia-activating factor 2.80.10.50 157 28 74 2.11 2.83
1dfcA02 84.67 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 9 85 1.97 2.31
1upsA02 84.27 Clostridium perfringensGlcNAc-alpha-1,4-Gal-releasing endo-beta-galactosidase 2.80.10.50 133 9 84 2.40 2.85
3c9zA02 83.37 Sambucus nigraNigrin b 2.80.10.50 125 6 81 1.99 2.44
1m2tB02 83.26 Beta-galactoside-specific lectin 1Viscum album 2.80.10.50 124 8 81 2.06 2.53
1dfcA01 83.16 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 122 13 87 2.79 3.18
1n4kA01 83.03 MicrosomeVoluntary musculoskeletal movementNucleolusPhosphoinositide bindingSarcoplasmic reticulum 2.80.10.50 141 14 75 2.04 2.71
1jlxA02 82.31 Amaranthus caudatusAgglutinin 2.80.10.50 140 6 80 2.42 3.02
1vclA02 81.86 Cucumaria echinataHemolytic lectin CEL-III 2.80.10.50 134 11 81 2.20 2.70
1w3fA01 81.70 Laetiporus sulphureusHemolytic lectin LSLa 2.80.10.50 147 11 76 2.27 2.95
1dfcA04 81.50 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 107 12 75 2.06 2.72
1wd3A02 80.87 Alpha-L-arabinofuranosidase BAspergillus awamori 2.80.10.50 162 8 71 2.23 3.11
2vxtI00 80.86 Cytokine activityInterleukin 18Signal transducer activityInterleukin-18Interferon-gamma biosynthetic process 2.80.10.50 156 9 71 2.38 3.34
1jlxA01 79.68 Amaranthus caudatusAgglutinin 2.80.10.50 159 11 72 2.55 3.50
1hcdA00 79.57 Membrane fractionPlasma membraneActin filament bindingHisactophilin-1Cytosol 2.80.10.50 118 16 86 3.07 3.56
1md6A00 79.44 Mus musculusInterleukin-1 family member 5Interleukin 1 family, member 5 (delta) 2.80.10.50 154 8 72 3.26 4.52
1t9fA00 79.13 Caenorhabditis elegansPutative uncharacterized protein 2.80.10.50 178 8 63 2.28 3.59
1sr4A00 78.92 Haemophilus ducreyiCytolethal distending toxin subunit ACytolethal distending toxin subunit A 2.80.10.50 167 9 70 3.43 4.90
1vclA01 78.65 Cucumaria echinataHemolytic lectin CEL-III 2.80.10.50 149 7 73 2.45 3.35
3iagC02 77.93 Transcription factor bindingHeart developmentRegulation of timing of cell differentiationDefense response to bacteriumNotch signaling pathway 2.80.10.50 155 8 60 2.34 3.86
2qn4A00 76.34 Oryza sativa Japonica GroupAlpha-amylase inhibitor activityAlpha-amylase/subtilisin inhibitorSerine-type endopeptidase inhibitor activity 2.80.10.50 159 9 69 3.17 4.58
Displaying entries 1 to 24 (page 1 of 1)


Domain ATOM Sequence

>pdb|1pwaA00
PIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDC
AFEEEIRPDGYNVYRSEKHRLPVSLSLPLSHFLPMLPMVPEEP    

Domain COMBS Sequence

>pdb|1pwaA00
GSMSGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQ
YSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEP    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:09

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"