CATH Domain: 1pq7A02 XML data for domain: 1pq7A02

Molscript image for 1pq7A02
1pq7A02
PDB coordinates for domain 1pq7A02

PDB 1pq7, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.6
2.40.10.10.6.1
2.40.10.10.6.1.1
2.40.10.10.6.1.1.1
2.40.10.10.6.1.1.1.1

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Segment boundaries for domain 1pq7A02

Chopping figure for domain 1pq7A02
DomainStart PDB ResidueStop PDB Residue
1pq7A01 16 27
1pq7A01 118 229
1pq7A02 28 117
1pq7A02 230 239

Structural Neighbourhood (47 entries)

There are 47 matching structural neighberhood comparisons for CATH ID 2.40.10.10.6.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 47 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1hj9A02 90.43 Neuroactive ligand-receptor interactionBos taurusCationic trypsinTrypsin [EC:3.4.21.4]Protein binding 2.40.10.10 103 32 91 1.42 1.56
1hj8A02 90.00 Salmo salarTrypsin-1 2.40.10.10 103 28 91 1.48 1.62
2qxiA02 89.77 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 27 91 1.38 1.50
3beuA02 89.66 Streptomyces griseusTrypsin 2.40.10.10 99 30 91 2.02 2.20
1bioA02 89.57 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 28 93 1.85 1.98
2wphS02 89.55 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 22 89 1.56 1.74
2hlcA01 89.50 CollagenaseHypoderma lineatum 2.40.10.10 104 24 89 2.58 2.89
3gylB02 89.43 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 33 89 1.54 1.73
1q3xA03 89.42 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 30 93 1.80 1.94
2jkhA02 89.36 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 27 92 1.89 2.05
1elvA01 89.29 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 26 88 1.65 1.86
1orfA02 89.22 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 24 91 1.76 1.93
2anyA02 89.16 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 29 88 1.79 2.03
1a7sA02 88.73 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 30 89 1.53 1.71
2asuB02 88.71 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 25 91 1.54 1.69
1nn6A02 88.64 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 24 88 2.00 2.25
1ym0A02 88.59 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 28 88 1.60 1.81
2f91A02 88.55 Pontastacus leptodactylusHepatopancreas trypsin 2.40.10.10 112 31 88 1.56 1.76
2bvrH02 88.46 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 116 31 85 1.56 1.83
1p57B02 88.44 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 35 83 1.39 1.66
1eaxA02 88.41 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 24 86 1.59 1.85
2r0lA02 88.10 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 19 86 1.47 1.69
1gj7B02 87.68 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 25 83 1.48 1.76
1fiwA02 87.67 Ovis ariesAcrosinDrug binding 2.40.10.10 120 28 82 1.77 2.15
1gvzA02 87.31 Equus caballusKallikrein-1E2 2.40.10.10 115 24 82 1.62 1.96
3govB02 86.71 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 29 79 1.50 1.88
2aiqA02 86.53 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 20 83 2.07 2.49
1p3cA02 85.93 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 25 86 2.31 2.66
1agjA02 85.42 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 19 85 2.59 3.04
2o8lA02 85.33 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 15 83 2.82 3.39
1rrkA02 84.80 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 23 72 2.56 3.52
1ky9A01 83.54 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 14 82 3.98 4.81
2pkaA00 82.39 Sus scrofaGlandular kallikrein 2.40.10.10 80 22 64 1.92 2.97
2h2zA02 81.75 Replicase polyprotein 1aSARS coronavirus 2.40.10.10 85 18 70 3.38 4.78
2qf3A01 81.57 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 12 71 2.50 3.49
2z9iC01 80.94 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 14 72 2.51 3.45
1sotA01 79.97 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 13 68 2.56 3.73
1lcyA01 79.96 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 22 71 2.62 3.68
1lvmA02 79.09 Genome polyproteinTobacco etch virus 2.40.10.10 106 7 77 3.72 4.81
2halA01 78.87 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 11 77 3.13 4.01
1arbA02 77.11 Achromobacter lyticusProtease 1 2.40.10.10 137 20 64 3.05 4.69
2qa9E01 76.14 Streptomyces griseusStreptogrisin-B 2.40.10.10 89 16 80 4.00 4.95
2hntC00 75.68 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 25 46 1.36 2.93
2h5cA01 75.11 Lysobacter enzymogenesAlpha-lytic protease 2.40.10.10 85 17 74 3.48 4.66
1befA02 74.17 2.40.10.10 85 7 68 3.17 4.62
1lcyA02 73.32 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Endoplasmic reticulum membraneParkinson's diseaseNucleus 2.40.10.10 84 7 61 2.94 4.77
1eptA00 69.60 Sus scrofaTrypsin 2.40.10.10 43 32 30 1.27 4.19
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Displaying entries 1 to 47 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1pq7A02
PFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLST
SIPSGGNIGYALRSFIDTYA
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1pq7A02
PFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLST
SIPSGGNIGYALRSFIDTYA
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:25

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:25

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:33

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"