CATH Domain: 1plqA00

1plqA00

PDB 1plq, Chain A, Domain 0

CATH Code	Level Description	Links
3	Alpha Beta
3.70	Box
3.70.10	Proliferating Cell Nuclear Antigen
3.70.10.10		Gene3D
3.70.10.10.7
3.70.10.10.7.1
3.70.10.10.7.1.1
3.70.10.10.7.1.1.1
3.70.10.10.7.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 1plqA00

Domain	Start PDB Residue	Stop PDB Residue
1plqA00	1	258

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (3 entries)

There are 3 matching structural neighberhood comparisons for CATH ID 3.70.10.10.7.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1sxjH02	80.29	DNA replicationProliferating cell nuclear antigenProliferating cell nuclear antigenPCNA complexProtein binding	3.10.150.10	125	96	48	0.81	1.67
1vpkA03	73.50	Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways	3.10.150.10	119	12	43	2.15	4.91
3d1gA03	73.14	Pyrimidine metabolismDNA replicationPurine metabolismMetabolic pathwaysHomologous recombination	3.10.150.10	119	11	43	2.06	4.70

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Domain ATOM Sequence

>pdb|1plqA00
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILR
CGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINI
MITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD
LKSGFLQFFLAPKFNDEE

BLAST against CATH

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Domain COMBS Sequence

>pdb|1plqA00
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILR
CGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINI
MITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD
LKSGFLQFFLAPKFNDEE

BLAST against CATH

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Domain History Events (20)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "1plq000" to "1plqA00" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Domain assigned by lewis on 09 Jan 2007 13:16

Assigning domain 1plq000 to 3.70.10.10 (as agreed with the CATH update team) after the chain has been rechopped. The reason is that the domain is very similar to the old domain 1plq000 (from the previous chopping at "Sun Mar 5 15:55:13 2006") which was in 3.70.10.10 at the time the chain was unchopped.