CATH Domain: 1piqA00 XML data for domain: 1piqA00

Molscript image for 1piqA00
1piqA00
PDB coordinates for domain 1piqA00

PDB 1piq, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.18
1.20.5.170.18.1
1.20.5.170.18.1.1
1.20.5.170.18.1.1.1
1.20.5.170.18.1.1.1.1

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Segment boundaries for domain 1piqA00

Chopping figure for domain 1piqA00
DomainStart PDB ResidueStop PDB Residue
1piqA00 1 31

Structural Neighbourhood (112 entries)

There are 112 matching structural neighberhood comparisons for CATH ID 1.20.5.170.18.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 112 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1a2xB00 95.75 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 9 96 0.50 0.52
1owaA01 91.69 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 12 90 0.74 0.82
1s3jB01 91.39 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 13 90 1.12 1.24
1omiA02 91.22 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 87 0.76 0.87
2hr3A01 90.85 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 3 87 1.43 1.64
2zxeB01 90.73 1.20.5.170 35 3 80 0.81 1.01
1tiiC00 90.65 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 9 77 1.00 1.29
1jmmA01 90.33 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 12 93 1.70 1.81
1r8eA03 88.90 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 25 70 0.38 0.54
1ow6A01 88.30 Focal adhesion kinase 1Focal adhesionCytoskeletonIntegrin-mediated signaling pathwayHomo sapiens 1.20.5.540 30 6 93 3.79 4.05
2r44A01 87.85 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 19 80 0.98 1.22
1lghB00 87.79 Phaeospirillum molischianumLight-harvesting protein B-800/850 beta 1 chain 1.20.5.250 43 6 72 0.86 1.19
1vf5C03 87.77 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 0 71 0.78 1.09
1kmiZ01 87.48 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.20.5.590 30 0 77 2.11 2.73
1ozhA03 87.41 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 8 74 1.05 1.42
1jekA00 87.02 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 9 65 0.57 0.88
2qjyC01 86.94 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 0 81 1.82 2.22
1nkzB00 86.43 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 6 75 3.28 4.34
1kv4A00 85.98 Moricin-1Bombyx mori 1.20.5.750 42 3 73 1.18 1.60
1ltsC00 85.87 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 6 75 2.87 3.80
1vl2B03 85.81 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 30 3 90 2.24 2.48
1qexA01 85.80 Enterobacteria phage T4Baseplate structural protein Gp9 1.20.5.960 35 3 80 2.27 2.84
2p10B02 85.57 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 7 77 2.12 2.74
1xmeB01 85.57 Cytochrome c oxidase subunit 2Thermus thermophilus 1.20.1070.10 44 6 70 1.25 1.77
2k1aA00 85.45 Integrin alpha 2BIdentical protein bindingPathways in cancerHematopoietic cell lineageDilated cardiomyopathy 1.20.5.930 42 3 73 3.01 4.08
1m7lA00 85.38 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 6 77 1.28 1.65
1hj0A00 85.12 Bos taurusThymosin beta-10 1.20.5.520 41 6 75 2.31 3.06
1mqsB00 85.01 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 3 83 1.96 2.34
3effK02 84.97 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 6 68 1.43 2.08
1h8bB00 84.55 TitinOryctolagus cuniculus 1.20.5.510 23 8 61 0.46 0.75
1ik7A00 84.15 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 19 59 0.73 1.22
1wa9B03 84.06 Regulation of circadian sleep/wake cycle, sleepPeriod circadian proteinNucleusResponse to temperature stimulusNegative regulation of transcription from RNA polymerase II promoter 1.20.5.770 33 0 75 2.82 3.72
3kpeA00 84.02 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 9 59 0.77 1.29
1qgkB00 84.01 DNA metabolic processG2 phase of mitotic cell cycleNuclear localization sequence bindingRegulation of DNA recombinationImportin subunit alpha-2 1.20.5.690 44 6 70 3.00 4.26
1be3K00 83.74 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 0 61 0.85 1.39
3c8vA04 83.45 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 61 0.83 1.35
1fs0E02 83.45 Oxidative phosphorylationMetabolic pathwaysATP synthase epsilon chainF-type H+-transporting ATPase subunit epsilon [EC:3.6.3.14]Escherichia coli K-12 1.20.5.440 38 6 60 2.05 3.39
1dipB01 83.19 Sus scrofaTSC22 domain family protein 3 1.20.5.490 45 12 68 2.18 3.16
1go9A00 83.11 1.20.5.480 39 19 69 1.72 2.48
2ifoA00 82.99 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 9 67 1.05 1.56
1ybkA00 82.99 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 9 59 1.19 2.00
2o01J01 82.64 Photosystem I reaction center subunit IXSpinacia oleracea 1.20.5.510 25 8 80 2.92 3.62
1hf9A00 82.61 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 12 75 2.67 3.53
1svfC00 82.56 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 3 50 0.33 0.66
1kqfB03 82.54 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 16 70 2.52 3.58
2oarA02 82.52 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 11 54 0.41 0.75
1l2pA00 82.14 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 19 49 0.51 1.04
1fdoA05 82.13 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 7 61 1.04 1.70
3b8eB00 82.01 Sodium/potassium-transporting ATPase subunit beta-1Sus scrofa 1.20.5.170 46 0 67 2.11 3.13
3efgA00 81.84 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 6 61 1.29 2.11
1n2dC00 81.55 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 9 56 1.03 1.83
1xrdA01 81.31 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 6 72 2.30 3.19
3cx5E01 80.75 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 3 56 1.30 2.31
1jocA01 80.69 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 6 51 0.74 1.43
1junA00 80.64 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 9 72 2.72 3.77
1nwqA00 80.36 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 12 51 0.71 1.37
1dh3A00 80.14 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 0 54 0.94 1.72
1pfiA00 80.09 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 3 52 1.28 2.45
3bz1H01 80.07 PhotosynthesisThermosynechococcus elongatus BP-1Photosystem II PsbH proteinPhotosystem II reaction center protein HMetabolic pathways 1.20.5.880 51 6 58 2.25 3.83
1avyB00 80.07 Enterobacteria phage T4Fibritin 1.20.5.320 54 0 50 1.26 2.52
1s5lX00 79.85 Photosystem II reaction center X proteinThermosynechococcus elongatus BP-1 1.20.5.510 40 9 72 2.76 3.81
3e7kA00 79.27 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 0 50 0.93 1.86
3clqB01 79.12 Enterococcus faecalisPutative uncharacterized protein 1.20.5.220 24 4 64 2.86 4.43
1ifpA00 78.59 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 6 70 3.44 4.88
1uixA00 78.16 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 9 45 1.03 2.26
1t6aA01 78.10 Geobacillus stearothermophilusRbstp2229 protein 1.20.5.850 43 0 46 1.18 2.54
2rh0A02 78.03 Mus musculusNudC domain-containing protein 2 1.20.5.740 29 0 64 3.00 4.65
1fjkA00 77.98 Calcium signaling pathwayDilated cardiomyopathySus scrofaCardiac phospholambanPhospholamban 1.20.5.290 52 12 59 2.56 4.29
1f8vD00 77.94 Pariacato virusProtein alpha 1.20.5.280 25 4 61 2.78 4.54
2oarE02 77.56 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 0 51 1.49 2.89
1avyA00 77.56 Enterobacteria phage T4Fibritin 1.20.5.320 68 19 44 0.97 2.20
1ic2B00 77.34 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 3 40 0.42 1.04
2dw3A01 77.20 Intrinsic membrane protein pufXRhodobacter sphaeroides 2.4.1 1.20.5.920 55 3 56 2.55 4.52
1wt6B00 77.03 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 3 46 1.32 2.85
1nknA00 76.72 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 6 41 0.88 2.10
1gk4C00 76.66 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 9 44 1.13 2.55
2w83C00 76.65 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 12 46 1.18 2.55
1mslA02 76.59 1.20.5.220 18 0 51 1.08 2.09
2wscH01 76.56 Photosystem I reaction center subunit VI, chloroplasticSpinacia oleracea 1.20.5.220 23 4 74 2.68 3.61
1jcdB00 76.24 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 9 44 1.68 3.80
1pp9E01 75.99 Cytochrome b-c1 complex subunit Rieske, mitochondrialBos taurus 1.20.5.270 64 0 43 1.04 2.38
1pl5A00 75.73 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 12 38 0.57 1.47
3ii6A02 75.71 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 9 50 1.73 3.46
1d66B02 75.71 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 13 48 0.62 1.28
1mkmA02 75.54 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 7 45 0.55 1.22
2ad6B00 75.42 Methylophilus methylotrophusMethanol dehydrogenase subunit 2 4.10.160.10 69 16 44 2.01 4.47
1no4C00 75.35 Bacillus phage phi29Head morphogenesis protein 1.20.5.400 73 6 42 1.58 3.72
1onvB00 74.77 CTD phosphatase activityProtein dephosphorylationHomo sapiensRNA polymerase II subunit A C-terminal domain phosphataseDNA-directed RNA polymerase activity 1.20.5.670 21 19 61 2.28 3.72
1u57A00 73.93 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 6 54 2.24 4.14
1ybzA00 73.53 Pyrococcus furiosusChorismate mutasePhenylalanine, tyrosine and tryptophan biosynthesisChorismate mutase [EC:5.4.99.5]Metabolic pathways 1.20.59.10 76 16 40 1.28 3.14
2jo1A00 72.45 Muscle contractionIntegral to plasma membraneFXYD domain-containing ion transport regulator 1PhospholemmanHomo sapiens 1.20.5.780 72 12 43 1.41 3.27
2aefB02 72.26 Methanothermobacter thermautotrophicus str. Delta HCalcium-gated potassium channel mthK 1.20.5.870 28 3 41 0.54 1.29
2wpqA00 72.01 Salmonella enterica subsp. enterica serovar TyphimuriumPutative inner membrane protein 1.20.5.980 99 90 30 0.50 1.65
2a19A02 71.94 Translation initiation factor activityTranslation initiation factor eIF-2 alpha subunitEukaryotic translation initiation factor 2 complexEukaryotic translation initiation factor 2 subunit alphaSaccharomyces cerevisiae 1.10.150.190 85 12 35 1.09 3.09
1d7mA00 71.92 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 19 30 0.52 1.69
2qiwA02 71.34 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 5 48 1.69 3.49
1ytzT00 71.25 Troponin T, fast skeletal muscle isoformsGallus gallus 1.20.5.350 90 19 34 0.74 2.15
2jp3A00 71.18 Potassium channel activityRattus norvegicusAldosterone-regulated sodium reabsorptionFXYD domain-containing ion transport regulator 4FXYD domain containing ion transport regulator 4 1.20.5.940 67 6 46 1.98 4.28
1j1dF01 71.05 Protein domain specific bindingCardiac muscle contractionDilated cardiomyopathyActin bindingNegative regulation of ATPase activity 1.20.5.350 102 22 30 0.53 1.74
2v4hB00 70.97 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 12 34 1.19 3.49
1ik9B02 70.39 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 12 28 0.55 1.90
1wqgA01 70.25 Ribosome recycling factorMycobacterium tuberculosisRibosome-recycling factor 1.10.132.20 109 6 28 0.57 2.00
2zvoB00 69.31 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 3 35 1.48 4.20
1aa0A00 66.55 Enterobacteria phage T4Fibritin 1.20.5.320 113 3 27 1.14 4.16
1envA00 66.42 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 115 12 26 0.80 2.97
2o01N01 65.79 Phaseolus vulgarisPhotosystem I-N subunit 1.20.5.740 22 0 70 3.35 4.72
1zvzA01 64.68 VinculinGallus gallus 1.20.1490.10 129 52 21 0.90 4.15
1j1eF00 64.39 Protein domain specific bindingCardiac muscle contractionDilated cardiomyopathyNegative regulation of ATPase activityActin binding 1.20.5.350 141 22 21 0.50 2.27
2b5uA02 61.80 Colicin-E3Escherichia coli 1.10.287.620 161 3 19 0.70 3.64
1zs8A01 59.58 Mus musculusMajor histocompatibility complex class Ib M10.5 3.30.500.10 171 3 18 0.85 4.69
1evsA00 58.03 Jak-STAT signaling pathwayOncostatin-M receptor complexCytokine activityOncostatin MCell proliferation 1.20.1250.10 163 3 15 0.51 3.20
2ap3A00 57.27 Staphylococcus aureus subsp. aureus MW2Putative uncharacterized protein MW0975 1.20.120.570 191 9 16 0.69 4.25
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Displaying entries 1 to 112 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1piqA00
RMKQIEDKIEEILSKQYHIENEIARIKKLIG
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1piqA00
XRMKQIEDKIEEILSKQYHIENEIARIKKLIG
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"