CATH Domain: 1opkA02 XML data for domain: 1opkA02

Molscript image for 1opkA02
1opkA02
PDB coordinates for domain 1opkA02

PDB 1opk, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.505 SHC Adaptor Protein
3.30.505.10 SHC Adaptor Protein Gene3D
3.30.505.10.6
3.30.505.10.6.1
3.30.505.10.6.1.1
3.30.505.10.6.1.1.1
3.30.505.10.6.1.1.1.1

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Segment boundaries for domain 1opkA02

Chopping figure for domain 1opkA02
DomainStart PDB ResidueStop PDB Residue
1opkA01 83 145
1opkA02 146 247
1opkA03 259 344
1opkA04 345 519

Structural Neighbourhood (14 entries)

There are 14 matching structural neighberhood comparisons for CATH ID 3.30.505.10.6.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 14 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2oq1A03 91.52 T cell receptor complexZeta-chain (TCR) associated protein kinase [EC:2.7.10.2]Natural killer cell mediated cytotoxicityPositive thymic T cell selectionTyrosine-protein kinase ZAP-70 3.30.505.10 99 36 90 1.38 1.53
2oq1A01 90.06 T cell receptor complexZeta-chain (TCR) associated protein kinase [EC:2.7.10.2]Natural killer cell mediated cytotoxicityPositive thymic T cell selectionTyrosine-protein kinase ZAP-70 3.30.505.10 108 27 92 2.96 3.20
1qadA00 89.13 Jak-STAT signaling pathwayAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathway 3.30.505.10 104 30 84 1.86 2.20
2crhA01 89.09 Vav oncogeneChemokine signaling pathwayB cell receptor signaling pathwayLeukocyte transendothelial migrationFc gamma R-mediated phagocytosis 3.30.505.10 102 31 88 1.52 1.72
1r1pB00 88.59 GRB2-related adaptor protein 2Mus musculusT cell receptor signaling pathwayProtein binding 3.30.505.10 100 30 84 1.55 1.84
1i3zA00 88.32 Mus musculusSH2 domain-containing protein 1BNegative regulation of natural killer cell mediated cytotoxicityNegative regulation of peptidyl-tyrosine phosphorylationPhosphotyrosine binding 3.30.505.10 102 30 90 2.34 2.59
2shpA02 88.27 Tyrosine-protein phosphatase non-receptor type 11Homo sapiens 3.30.505.10 101 34 87 1.89 2.17
1ayaA00 88.05 Hormone-mediated signaling pathwayRegulation of multicellular organism growthNerve growth factor receptor signaling pathwayTriglyceride metabolic processNegative regulation of insulin secretion 3.30.505.10 101 33 89 2.13 2.39
2iugA00 87.33 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 3.30.505.10 110 27 86 2.77 3.21
3bkbA01 86.57 Tyrosine-protein kinase Fes/FpsHomo sapiensCell proliferationMulticellular organismal development 3.30.505.10 93 24 80 3.03 3.77
1milA00 86.39 Transmembrane receptor protein tyrosine kinase adaptor activitySHC-transforming protein 1Regulation of epidermal growth factor receptor activityEpidermal growth factor receptor signaling pathwayInsulin-like growth factor receptor binding 3.30.505.10 104 28 87 2.12 2.42
2kk6A00 85.53 CytoplasmFer (fps/fes related) tyrosine kinase [EC:2.7.10.2]Homo sapiensAdherens junctionTyrosine-protein kinase Fer 3.30.505.10 116 31 81 1.92 2.37
1ju5A00 84.60 Pathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayFc gamma R-mediated phagocytosisErbB signaling pathway 3.30.505.10 109 32 83 2.53 3.03
2vifA01 84.38 CytoplasmJAK-STAT cascadeDefense responseSuppressor of cytokine signaling 6Suppressor of cytokine signaling 6 3.30.505.10 126 26 75 2.53 3.36
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Displaying entries 1 to 14 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1opkA02
WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVA
DGLITTLHYPAPKRNKPTIYGV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1opkA02
WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVA
DGLITTLHYPAPKRNKPTIYGV
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 19:07

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 19:07

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:27

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"