CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family Mitochondrial aldehyde dehydrogenase 2

Enzyme Information

1.2.1.3
Aldehyde dehydrogenase (NAD(+)).
based on mapping to UniProt P05091
An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
-!- Wide specificity, including oxidation of D-glucuronolactone to D-glucarate. -!- Formerly EC 1.1.1.70.

UniProtKB Entries (1)

P05091
ALDH2_HUMAN
Homo sapiens
Aldehyde dehydrogenase, mitochondrial

PDB Structure

PDB 1NZW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase
Perez-Miller, S.J., Hurley, T.D.
Biochemistry