CATH Domain: 1nwqA00 XML data for domain: 1nwqA00

Molscript image for 1nwqA00
1nwqA00
PDB coordinates for domain 1nwqA00

PDB 1nwq, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.20
1.20.5.170.20.1
1.20.5.170.20.1.1
1.20.5.170.20.1.1.1
1.20.5.170.20.1.1.1.1

Segment boundaries for domain 1nwqA00

Chopping figure for domain 1nwqA00
DomainStart PDB ResidueStop PDB Residue
1nwqA00 281 340

Structural Neighbourhood (65 entries)

There are 65 matching structural neighberhood comparisons for CATH ID 1.20.5.170.20.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 65 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1gmjD00 88.11 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 8 83 1.42 1.70
1n2dC00 87.97 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 6 78 1.03 1.31
1jocA01 87.29 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 6 96 2.38 2.46
2b9bA04 87.25 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 3 87 2.31 2.65
1ybkA00 86.61 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 11 81 2.26 2.77
1jekA00 85.37 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 10 66 0.99 1.48
1ic2B00 84.94 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 3 77 2.18 2.80
1e5wA04 84.40 Leukocyte migrationReceptor bindingCytoskeletonMembrane to membrane dockingNucleolus 1.20.5.450 55 3 80 3.44 4.30
1gk4C00 84.18 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 6 81 2.83 3.48
1pl5A00 83.85 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 13 62 0.92 1.47
2o1kA00 83.84 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 4 70 1.66 2.37
1xmeB01 83.64 Cytochrome c oxidase subunit 2Thermus thermophilus 1.20.1070.10 44 48 73 3.49 4.76
1kilE00 83.12 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 9 68 2.56 3.75
3kpeA00 83.06 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 6 78 2.94 3.75
1tiiC00 82.89 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 5 60 1.55 2.58
2ifoA00 82.85 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 2 76 2.56 3.34
1hf9A00 81.87 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 9 68 1.65 2.41
1junA00 81.78 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 6 71 2.83 3.95
1no4C00 81.41 Bacillus phage phi29Head morphogenesis protein 1.20.5.400 73 10 71 2.92 4.10
1svfC00 81.23 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 1 59 1.31 2.20
1l2pA00 81.11 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 3 55 1.20 2.15
1wt6B00 80.95 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 10 73 3.32 4.54
1u57A00 80.90 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 6 75 2.42 3.23
1nkzB00 80.89 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 7 63 2.92 4.61
1jcdB00 80.51 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 5 55 1.00 1.82
3efgA00 80.46 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 10 70 2.22 3.17
1favA00 80.44 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 5 66 3.04 4.56
2zvoB00 80.01 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 8 63 2.42 3.80
2zjsE00 79.84 Protein exportBacterial secretion systemThermus thermophilus HB8Preprotein translocase subunit secEPreprotein translocase subunit SecE 1.20.5.1030 46 6 70 2.87 4.10
1ifpA00 79.43 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 2 68 2.40 3.51
1r8eA03 79.26 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 6 56 1.68 2.96
1ik7A00 79.21 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 5 51 1.09 2.11
3gwoA00 79.14 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 1 56 2.22 3.92
2qjyC01 79.12 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 9 55 1.59 2.89
1omiA02 78.76 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 11 45 0.58 1.29
2v4hB00 78.72 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 8 61 2.53 4.11
1kv4A00 78.57 Moricin-1Bombyx mori 1.20.5.750 42 4 66 2.80 4.20
1a2xB00 77.91 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 12 48 1.13 2.34
1pfiA00 77.80 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 0 50 1.43 2.86
3cx5E01 77.71 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 5 51 1.64 3.17
2dw3A01 77.68 Intrinsic membrane protein pufXRhodobacter sphaeroides 2.4.1 1.20.5.920 55 3 63 2.94 4.64
2hr3A01 77.59 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 3 50 1.64 3.28
1uixA00 77.36 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 1 47 1.17 2.49
2zxeB01 77.29 1.20.5.170 35 0 46 1.38 2.96
1vf5C03 77.01 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 18 53 1.82 3.41
2w83C00 76.28 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 5 46 1.62 3.50
1htmD00 75.06 HemagglutininInfluenza A virus (A/Aichi/2/1968(H3N2)) 3.90.20.10 123 1 45 1.66 3.65
1s3jB01 74.52 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 6 50 2.14 4.28
1bmfG00 74.08 Bos taurusATP synthase subunit gamma, mitochondrialProtein binding 1.10.287.80 122 10 49 1.69 3.44
2r44A01 74.07 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 7 43 0.88 2.03
1ik9B02 73.56 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 3 39 1.11 2.79
1kmiZ01 72.65 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.20.5.590 30 0 43 1.97 4.55
1be3K00 72.08 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 9 36 1.01 2.75
2p10B02 72.05 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 15 43 1.86 4.29
2oarE02 72.00 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 9 36 1.19 3.25
1fdoA05 71.73 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 18 40 1.09 2.73
3ii6A02 68.69 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 6 38 1.24 3.23
3c8vA04 68.11 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 10 31 0.87 2.75
2oarA02 67.26 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 11 28 0.37 1.31
1mslA02 64.95 1.20.5.220 18 0 30 1.34 4.47
2qiwA02 64.79 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 11 30 1.11 3.70
3clqB01 64.78 Enterococcus faecalisPutative uncharacterized protein 1.20.5.220 24 4 30 0.90 3.00
2r05A03 63.41 Homo sapiensProgrammed cell death 6-interacting proteinCalcium-dependent protein binding 1.20.140.50 189 1 22 0.94 4.13
1d66B02 63.02 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 20 25 0.38 1.52
1mkmA02 60.08 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 0 23 0.56 2.40
Displaying entries 1 to 65 (page 1 of 1)


Domain ATOM Sequence

>pdb|1nwqA00
NSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRG    

Domain COMBS Sequence

>pdb|1nwqA00
GSNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRG    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"