CATH Domain: 1nhlA00 XML data for domain: 1nhlA00

Molscript image for 1nhlA00
1nhlA00
PDB coordinates for domain 1nhlA00

PDB 1nhl, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.15
1.20.5.110.15.1
1.20.5.110.15.1.1
1.20.5.110.15.1.1.1
1.20.5.110.15.1.1.1.1

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Segment boundaries for domain 1nhlA00

Chopping figure for domain 1nhlA00
DomainStart PDB ResidueStop PDB Residue
1nhlA00 28 81

Structural Neighbourhood (87 entries)

There are 87 matching structural neighberhood comparisons for CATH ID 1.20.5.110.15.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 87 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ik7A00 89.06 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 9 96 2.02 2.10
1nwqA00 88.13 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 11 86 1.14 1.32
1gmjD00 87.93 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 11 85 1.90 2.22
1jocA01 87.78 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 7 81 1.40 1.71
3e7kA00 86.78 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 7 90 2.00 2.20
3kpeA00 86.74 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 8 78 1.16 1.47
1dh3A00 86.61 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 13 89 2.03 2.28
1ci6A00 86.59 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 5 82 2.22 2.70
2o1kA00 86.41 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 78 1.61 2.04
1ybkA00 86.41 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 5 86 2.75 3.18
1jcdB00 86.12 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 5 88 2.43 2.75
1l2pA00 85.72 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 9 85 2.84 3.33
1jekA00 85.16 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 10 73 1.22 1.67
1g2cB00 84.63 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 2 75 3.21 4.28
1ezjA02 84.54 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 9 94 3.72 3.95
2b9bA04 84.53 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 5 79 2.74 3.47
1piqA00 83.64 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 19 57 0.64 1.11
2h8pD00 83.55 1.20.5.110 43 13 73 2.32 3.17
1gk4C00 83.52 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 15 74 2.52 3.39
3gwoA00 83.48 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 9 86 3.24 3.73
1jnmA00 83.12 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 13 85 2.63 3.07
1tiiC00 82.93 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 5 67 2.68 3.98
1ifpA00 82.82 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 4 67 1.27 1.89
3efgA00 82.79 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 2 82 3.34 4.04
1favA00 82.48 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 11 66 0.70 1.05
1hf9A00 82.23 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 2 76 2.61 3.39
3ii6A02 82.14 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 13 89 3.53 3.94
2p7jB01 81.98 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 2 65 1.55 2.37
1ik9B02 81.95 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 9 62 1.15 1.84
1nknA00 81.91 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 13 63 1.17 1.84
1kilE00 81.72 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 2 57 1.74 3.02
1ic2B00 81.70 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 9 67 2.42 3.58
1svfC00 81.55 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 5 72 2.92 4.02
1r8eA03 81.42 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 0 63 1.69 2.66
1qgkB00 81.31 DNA metabolic processG2 phase of mitotic cell cycleNuclear localization sequence bindingRegulation of DNA recombinationImportin subunit alpha-2 1.20.5.690 44 4 67 3.14 4.67
1wdcA00 81.13 Myosin heavy chain, striated muscleArgopecten irradians 4.10.270.10 64 17 78 3.38 4.33
1junA00 80.88 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 6 65 2.28 3.49
2w83C00 80.73 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 5 70 2.65 3.78
1gu4A00 80.73 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 7 80 3.91 4.89
1gk6B00 80.69 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 1 69 3.37 4.87
2qjyC01 80.44 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 12 59 1.38 2.31
2p2uA01 79.93 Desulfovibrio vulgaris str. HildenboroughHost-nuclease inhibitor protein Gam, putative 1.20.5.170 69 7 75 2.64 3.50
2zxeB01 79.90 1.20.5.170 35 14 53 0.84 1.56
2ifoA00 79.85 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 6 80 3.58 4.43
2basA02 79.36 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 6 57 1.17 2.03
1a2xB00 79.19 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 12 53 0.90 1.67
3cx5E01 79.12 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 5 56 1.39 2.47
1avyB00 78.66 Enterobacteria phage T4Fibritin 1.20.5.320 54 7 77 3.74 4.81
1hj0A00 78.58 Bos taurusThymosin beta-10 1.20.5.520 41 4 61 2.46 4.00
2hr3A01 78.17 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 10 55 1.63 2.92
1n2dC00 77.72 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 2 50 1.17 2.34
1m56D00 77.70 Rhodobacter sphaeroidesAa3-type cytochrome c oxidase subunit IV 1.20.5.160 42 2 55 1.66 2.98
1kv4A00 77.52 Moricin-1Bombyx mori 1.20.5.750 42 4 61 2.23 3.62
2zvoB00 77.48 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 19 59 1.35 2.28
1vf5C03 77.32 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 9 55 1.98 3.55
1m7lA00 77.26 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 0 55 1.38 2.47
1xrdA01 77.16 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 4 75 3.61 4.81
1s3jB01 77.09 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 3 57 2.51 4.35
2v4hB00 77.06 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 7 57 2.05 3.59
1jmmA01 76.74 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 18 51 1.53 2.95
1fdoA05 76.64 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 11 50 1.69 3.38
2r44A01 76.42 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 11 50 1.54 3.08
1owaA01 76.27 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 9 61 3.07 4.99
3hd7B00 75.66 Myosin head/neck bindingActomyosinProtein domain specific bindingRattus norvegicusProtein heterodimerization activity 1.20.5.110 98 5 53 2.26 4.26
1go9A00 75.61 1.20.5.480 39 2 48 1.58 3.29
1d7mA00 75.27 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 7 44 1.21 2.72
1envA00 74.95 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 115 9 45 1.41 3.12
1no4C00 74.45 Bacillus phage phi29Head morphogenesis protein 1.20.5.400 73 0 42 1.35 3.18
2v7qJ00 74.43 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 43 11 40 0.54 1.34
2p1jB02 73.58 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 3 36 0.39 1.07
1wt6B00 73.57 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 5 41 1.25 2.99
2dw4A03 73.54 Lysine-specific histone demethylase 1AHistone demethylase activityNucleusTranscription repressor activityHomo sapiens 1.10.287.80 101 3 45 2.07 4.54
2p1jA02 72.06 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 3 36 1.05 2.87
2pp6A01 71.53 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 4 40 1.13 2.80
1slqF02 71.34 Outer capsid protein VP4Rhesus rotavirus 1.20.5.170 32 9 36 0.65 1.78
1dp5B00 71.17 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 16 34 0.62 1.79
1czqA00 70.99 1.20.5.170 45 6 34 0.63 1.82
2oarA02 70.90 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 35 32 0.47 1.44
1be3K00 68.98 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 0 32 0.79 2.42
3c8vA04 68.82 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 34 0.89 2.57
2qiwA02 67.63 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 5 32 0.86 2.63
1omiA02 67.52 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 30 0.58 1.89
1mslA02 66.20 1.20.5.220 18 0 34 1.37 3.96
3g67A00 65.31 Thermotoga maritimaMethyl-accepting chemotaxis protein, putative 1.10.287.950 213 9 24 0.78 3.19
1d66B02 65.23 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 6 28 0.53 1.84
2r05A03 64.39 Homo sapiensProgrammed cell death 6-interacting proteinCalcium-dependent protein binding 1.20.140.50 189 5 27 1.30 4.72
1mkmA02 61.40 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 0 26 0.75 2.79
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Displaying entries 1 to 87 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1nhlA00
STRRILGLAIESQDAGIKTITLDEQKEQLNRIEEGLDQINKDRETEKTLTEL
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1nhlA00
STRRILGLAIESQDAGIKTITXLDEQKEQLNRIEEGLDQINKDXRETEKTLTEL
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"