CATH Domain: 1ng2A02 XML data for domain: 1ng2A02

Molscript image for 1ng2A02
1ng2A02
PDB coordinates for domain 1ng2A02

PDB 1ng2, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.19
2.30.30.40.19.1
2.30.30.40.19.1.1
2.30.30.40.19.1.1.1
2.30.30.40.19.1.1.1.1

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Segment boundaries for domain 1ng2A02

Chopping figure for domain 1ng2A02
DomainStart PDB ResidueStop PDB Residue
1ng2A01 157 200
1ng2A02 215 282

Structural Neighbourhood (36 entries)

There are 36 matching structural neighberhood comparisons for CATH ID 2.30.30.40.19.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 36 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ov3A02 93.02 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 100 79 0.53 0.67
2v1rA00 89.74 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 20 86 2.16 2.49
1ycsB02 88.94 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 25 88 3.03 3.43
2jteA00 88.82 Mus musculusCD2-associated protein 2.30.30.40 64 25 88 1.78 2.02
2j6fA00 88.81 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 26 79 1.30 1.64
1ad5A01 88.61 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 23 80 1.54 1.90
1yn8A00 88.56 NucleusHyperosmotic responseResponse to heatNegative regulation of protein kinase activityProtein binding 2.30.30.40 59 25 80 1.07 1.32
1wx6A01 88.27 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 19 83 1.60 1.91
2vwfA00 88.20 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 21 79 1.35 1.70
2vknA00 88.17 MAPK signaling pathway - yeastIdentical protein bindingMating projection tipPseudohyphal growthOsmosensor activity 2.30.30.40 66 24 83 1.79 2.14
2rqtA00 87.45 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 21 80 1.53 1.89
1x6bA01 87.28 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 25 80 1.54 1.90
3ehrB01 87.09 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 19 82 1.93 2.34
2csqA01 87.04 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 16 80 1.54 1.90
1jegA00 86.71 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 16 82 1.64 1.99
1griA01 86.58 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 22 70 0.99 1.40
1gcqC00 86.32 Integrin-mediated signaling pathwayProto-oncogene vavProtein bindingMus musculusT cell differentiation 2.30.30.40 69 16 84 2.53 3.01
1awwA00 85.99 Phosphatidylinositol-3,4,5-trisphosphate bindingInduction of apoptosis by extracellular signalsIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.30.40 67 19 91 3.03 3.32
1ng2A01 84.34 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 34 64 1.39 2.15
2ke9A00 84.19 Caskin-2Homo sapiens 2.30.30.40 67 17 82 2.13 2.59
1u3oA01 83.90 Rattus norvegicusVesicle-mediated transportProtein bindingAxonogenesisNeuron projection 2.30.30.40 62 24 82 2.27 2.76
3i5rA00 83.26 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 2.30.30.40 81 19 71 2.50 3.49
1i1jB00 82.07 Melanoma-derived growth regulatory proteinHomo sapiensExtracellular spaceCell proliferation 2.30.30.40 103 22 65 2.87 4.41
1jxmA01 81.86 Postsynaptic membraneRattus norvegicusProtein C-terminus bindingIonotropic glutamate receptor bindingDisks large homolog 4 2.30.30.40 80 19 65 2.43 3.74
1dj7B00 81.57 Ferredoxin-thioredoxin reductase, variable chainProtein bindingSynechocystis sp. PCC 6803 2.30.30.50 73 10 79 3.86 4.86
1udlA00 81.09 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 98 29 69 3.18 4.58
2heqA01 81.05 Bacillus subtilisSPBc2 prophage-derived uncharacterized protein yorP 2.30.30.40 54 11 73 2.72 3.70
2g3rA01 80.50 CytoplasmHomo sapiensTumor suppressor p53-binding protein 1Protein binding 2.30.30.140 53 11 70 2.79 3.95
1m9sA04 80.08 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 86 10 75 3.47 4.59
1m9sA05 80.02 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 78 13 76 2.91 3.78
1jb0E00 79.71 Photosystem I subunit IVPhotosynthesisThermosynechococcus elongatus BP-1Photosystem I reaction center subunit IVMetabolic pathways 2.30.30.50 69 13 72 3.12 4.31
2rh2A00 79.50 Dihydrofolate reductase type 2Escherichia coli 2.30.30.60 57 5 70 3.23 4.58
2o2oA00 78.93 NucleusHomo sapiensSH3 domain-containing kinase-binding protein 1 2.30.30.40 75 22 84 3.09 3.68
1biaA03 77.95 Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity 2.30.30.100 47 8 67 2.94 4.35
3by7E00 73.07 2.30.30.100 74 7 55 2.59 4.67
2ra2B00 72.38 Salmonella enterica subsp. enterica serovar TyphimuriumPutative lipoprotein 2.30.30.100 55 7 66 3.26 4.93
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Displaying entries 1 to 36 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1ng2A02
SPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1ng2A02
SPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQK
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:20

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"