CATH Domain: 1n7sB00 XML data for domain: 1n7sB00

Molscript image for 1n7sB00
1n7sB00
PDB coordinates for domain 1n7sB00

PDB 1n7s, Chain B, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.2
1.20.5.110.2.1
1.20.5.110.2.1.1
1.20.5.110.2.1.1.1
1.20.5.110.2.1.1.1.1

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Segment boundaries for domain 1n7sB00

Chopping figure for domain 1n7sB00
DomainStart PDB ResidueStop PDB Residue
1n7sB00 189 256

Structural Neighbourhood (71 entries)

There are 71 matching structural neighberhood comparisons for CATH ID 1.20.5.110.2.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 71 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3b5nJ00 93.24 Cellular membrane fusionSNARE complexPhosphatidylinositol-3,5-bisphosphate bindingSyntaxin 1B/2/3Prospore membrane 1.20.5.110 64 48 94 0.74 0.79
1jthB00 91.73 Protein domain specific bindingMyosin head/neck bindingActomyosinRattus norvegicusProtein heterodimerization activity 1.20.5.110 67 98 97 1.67 1.72
1pl5A00 89.32 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 16 90 1.76 1.94
3b5nA00 88.49 Synaptobrevin homolog 1Vesicle fusionSNAP receptor activityPlasma membraneVesicle-associated membrane protein 4 1.20.5.110 61 9 89 2.15 2.40
1n7sA00 87.45 SNARE interactions in vesicular transportVasopressin-regulated water reabsorptionRattus norvegicusProtein complex bindingVesicle-mediated transport 1.20.5.110 63 7 92 2.10 2.27
1t3jA00 87.10 Mus musculusMitochondrial fusionMitofusin-1Protein binding 1.20.5.110 62 4 91 2.85 3.13
1uixA00 87.03 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 13 95 2.65 2.77
1l2pA00 86.94 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 8 89 2.13 2.37
2e42A00 85.99 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 4 94 3.24 3.44
1svfC00 85.83 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 9 77 1.95 2.50
3hd7B00 85.80 Myosin head/neck bindingActomyosinProtein domain specific bindingRattus norvegicusProtein heterodimerization activity 1.20.5.110 98 97 68 1.11 1.62
1ik7A00 85.53 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 5 64 2.05 3.17
1ci6A00 85.32 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 8 82 2.54 3.08
1wt6B00 84.79 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 7 91 3.44 3.77
1czqA00 83.42 1.20.5.170 45 6 66 1.42 2.15
1urqC00 83.41 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 68 2 63 0.97 1.53
3gwoA00 83.14 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 5 77 2.92 3.75
1nwqA00 82.61 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 8 73 2.78 3.78
1ezjA02 82.10 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 5 67 2.98 4.41
1sfcH00 82.02 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 72 4 69 2.00 2.88
2o1kA00 81.91 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 54 0.80 1.47
1gl2C00 81.79 Mus musculusVesicle transport through interaction with t-SNAREs homolog 1BGolgi apparatusProtein binding 1.20.5.110 59 8 77 3.35 4.30
2v4hB00 81.16 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 7 67 1.66 2.48
1ifpA00 80.91 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 6 64 1.84 2.84
1jocA01 80.55 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 10 58 1.09 1.85
2basA02 80.45 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 15 67 1.89 2.79
1tiiC00 80.19 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 8 52 1.99 3.76
1nknA00 80.15 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 4 89 3.91 4.38
3kpeA00 80.05 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 10 69 3.10 4.49
1jcdB00 80.01 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 5 52 1.51 2.85
3efgA00 79.28 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 14 64 2.50 3.86
1favA00 78.94 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 4 56 2.57 4.56
1ci6B00 78.90 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 6 60 1.65 2.74
1hf9A00 78.73 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 7 60 2.03 3.37
3effK02 78.69 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 2 58 2.83 4.81
1kv4A00 78.36 Moricin-1Bombyx mori 1.20.5.750 42 7 61 2.77 4.48
1junA00 78.23 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 9 47 0.90 1.91
1r8eA03 78.20 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 2 58 2.45 4.17
1m56D00 78.17 Rhodobacter sphaeroidesAa3-type cytochrome c oxidase subunit IV 1.20.5.160 42 7 61 2.51 4.06
1jekA00 77.98 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 7 58 2.47 4.20
3fx7A00 77.80 Helicobacter pyloriPutative uncharacterized protein 1.10.287.850 83 4 49 1.83 3.70
1nhlA00 77.25 Vesicle targetingAzurophil granuleCellular membrane fusionSynaptosomal-associated protein 23Protein binding 1.20.5.110 52 7 50 1.81 3.62
1aa0A00 77.15 Enterobacteria phage T4Fibritin 1.20.5.320 113 7 58 2.58 4.42
1piqA00 77.02 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 16 45 0.96 2.11
1omiA02 76.99 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 3 39 0.43 1.08
1l4aA00 76.96 SynaptobrevinLoligo pealei 1.20.5.110 66 1 64 3.20 4.95
1pfiA00 76.31 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 10 63 3.14 4.97
1dp5B00 75.80 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 3 45 1.36 2.98
1u57A00 75.73 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 10 51 1.70 3.30
1m7lA00 74.83 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 10 48 2.28 4.70
3b8eB00 74.65 Sodium/potassium-transporting ATPase subunit beta-1Sus scrofa 1.20.5.170 46 2 48 2.37 4.88
1gmjD00 74.09 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 8 44 2.04 4.62
1a2xB00 73.45 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 6 45 1.94 4.26
1vf5C03 71.80 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 9 36 0.91 2.48
1qexA01 71.77 Enterobacteria phage T4Baseplate structural protein Gp9 1.20.5.960 35 2 39 1.92 4.84
2p1jA02 71.30 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 7 36 1.69 4.60
2k37A00 71.20 Bacteriochlorophyll c-binding proteinChlorobaculum tepidumChlorosome envelope protein A 1.20.5.950 59 1 42 1.77 4.15
1fdoA05 71.07 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 7 38 1.46 3.82
2oarE02 70.98 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 4 32 1.28 3.96
1ybkA00 70.93 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 9 35 1.72 4.87
1be3K00 69.35 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 13 32 1.03 3.18
1mqsB00 69.30 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 7 38 1.50 3.92
1s3jB01 69.10 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 6 32 1.60 4.95
1deeG00 67.03 Staphylococcus aureus subsp. aureus NCTC 8325Immunoglobulin G-binding protein A 1.20.5.420 51 7 32 1.58 4.88
2pp6A01 66.26 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 4 30 1.06 3.43
1h8bB00 66.13 TitinOryctolagus cuniculus 1.20.5.510 23 21 32 1.49 4.61
2oarA02 66.10 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 25 0.46 1.84
2qiwA02 63.94 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 11 26 0.96 3.63
3c8vA04 62.53 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 21 27 1.35 4.83
1d66B02 59.51 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 6 22 0.54 2.45
1mkmA02 56.53 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 7 20 0.77 3.74
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Displaying entries 1 to 71 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1n7sB00
GSALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVK
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1n7sB00
GSALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVK
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"