CATH Domain: 1n7sA00 XML data for domain: 1n7sA00

Molscript image for 1n7sA00
1n7sA00
PDB coordinates for domain 1n7sA00

PDB 1n7s, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.3
1.20.5.110.3.1
1.20.5.110.3.1.1
1.20.5.110.3.1.1.1
1.20.5.110.3.1.1.1.1

[top]
Segment boundaries for domain 1n7sA00

Chopping figure for domain 1n7sA00
DomainStart PDB ResidueStop PDB Residue
1n7sA00 27 89

Structural Neighbourhood (83 entries)

There are 83 matching structural neighberhood comparisons for CATH ID 1.20.5.110.3.1.1.1.1 (SIMAX score < 5)

[1]
Displaying entries 1 to 83 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1gl2A00 89.28 Rattus norvegicusProtein complex assemblyVesicle-associated membrane protein 8Cellular membrane fusionVesicle-associated membrane protein 8 1.20.5.110 53 32 84 1.15 1.37
1urqC00 88.60 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 68 12 92 2.11 2.28
1t3jA00 88.11 Mus musculusMitochondrial fusionMitofusin-1Protein binding 1.20.5.110 62 12 96 2.77 2.86
1gd2F00 87.99 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 14 98 1.68 1.71
1wt6B00 87.94 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 11 94 2.94 3.13
1jthB00 87.08 Protein domain specific bindingMyosin head/neck bindingActomyosinRattus norvegicusProtein heterodimerization activity 1.20.5.110 67 7 94 2.21 2.35
1l4aA00 87.06 SynaptobrevinLoligo pealei 1.20.5.110 66 14 84 1.35 1.59
3ii6A02 86.04 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 5 82 1.91 2.31
3e7kA00 85.94 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 7 84 1.95 2.32
1jcdB00 85.81 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 11 77 2.37 3.05
1uixA00 85.70 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 6 92 2.99 3.23
3b5nA00 85.69 Synaptobrevin homolog 1Vesicle fusionSNAP receptor activityPlasma membraneVesicle-associated membrane protein 4 1.20.5.110 61 11 73 1.26 1.73
3b5nJ00 85.41 Cellular membrane fusionSNARE complexPhosphatidylinositol-3,5-bisphosphate bindingSyntaxin 1B/2/3Prospore membrane 1.20.5.110 64 11 93 3.41 3.64
1jnmA00 84.58 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 1 73 1.73 2.37
1ci6B00 84.47 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 23 69 1.27 1.82
1gk6B00 83.46 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 9 63 1.37 2.16
1gl2B00 83.44 Mus musculusSyntaxin-7 1.20.5.110 59 13 90 4.01 4.43
1nknA00 82.98 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 12 77 2.73 3.54
2p2uA01 82.64 Desulfovibrio vulgaris str. HildenboroughHost-nuclease inhibitor protein Gam, putative 1.20.5.170 69 11 91 3.52 3.86
1ezjA02 82.51 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 5 80 3.74 4.62
2o1kA00 81.74 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 9 57 0.96 1.68
1gl2D00 81.71 Syntaxin-8Rattus norvegicusProtein bindingSyntaxin 8SNARE interactions in vesicular transport 1.20.5.110 54 11 84 3.17 3.77
1ybkA00 81.53 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 7 82 3.92 4.75
2basA02 80.79 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 6 71 3.20 4.48
1sfcH00 80.66 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 72 7 84 3.45 4.07
3kpeA00 80.30 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 4 53 1.40 2.59
1czqA00 79.99 1.20.5.170 45 8 49 0.95 1.93
2ifoA00 79.51 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 4 73 2.00 2.74
1piqA00 79.38 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 12 49 0.83 1.69
1nwqA00 79.04 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 8 68 3.40 4.98
1g2cB00 78.84 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 10 61 2.37 3.83
1gu4A00 78.09 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 4 53 2.03 3.77
2v4hB00 77.91 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 3 69 2.77 4.00
1ic2B00 77.89 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 6 61 3.04 4.98
1gk4C00 77.69 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 3 50 2.49 4.98
1r8eA03 77.65 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 15 63 3.08 4.85
1u57A00 77.15 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 4 73 2.82 3.86
1n2dC00 76.62 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 6 49 1.63 3.31
2zxeB01 76.43 1.20.5.170 35 11 55 2.66 4.79
1avyA00 76.40 Enterobacteria phage T4Fibritin 1.20.5.320 68 1 44 1.23 2.79
1s5lX00 76.27 Photosystem II reaction center X proteinThermosynechococcus elongatus BP-1 1.20.5.510 40 10 52 2.03 3.88
3hd7B00 76.26 Myosin head/neck bindingActomyosinProtein domain specific bindingRattus norvegicusProtein heterodimerization activity 1.20.5.110 98 4 51 2.24 4.39
1owaA01 75.94 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 9 50 2.26 4.45
1svfC00 75.88 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 4 47 2.05 4.30
2eboA00 75.75 Zaire ebolavirus - Mayinga (Zaire, 1976)Envelope glycoprotein 1.10.287.210 74 4 47 1.54 3.26
1ci6A00 75.67 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 7 50 1.75 3.45
1junA00 75.63 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 4 50 1.73 3.41
2rklB00 75.45 Multivesicular bodyVacuolar protein sorting-associated protein VTA1Membrane fractionProtein bindingEndocytosis 1.20.5.420 50 6 44 1.20 2.70
1a02F00 75.31 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 5 44 0.99 2.23
1hf9A00 75.28 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 4 44 1.28 2.88
1omiA02 75.07 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 42 0.88 2.05
1t6aA01 74.89 Geobacillus stearothermophilusRbstp2229 protein 1.20.5.850 43 2 46 1.59 3.45
1hj0A00 74.76 Bos taurusThymosin beta-10 1.20.5.520 41 12 55 2.62 4.72
2qjyC01 74.70 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 21 46 1.48 3.22
1j1dF01 74.35 Protein domain specific bindingCardiac muscle contractionDilated cardiomyopathyActin bindingNegative regulation of ATPase activity 1.20.5.350 102 14 46 1.73 3.75
1jmmA01 74.25 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 12 50 2.03 4.00
1avyB00 74.19 Enterobacteria phage T4Fibritin 1.20.5.320 54 3 44 1.17 2.63
2k9yA00 73.96 ApoptosisIntegral to plasma membraneEphrin type-A receptor 2Homo sapiensEph receptor A2 [EC:2.7.10.1] 1.20.5.510 41 2 46 1.97 4.28
1xmeB01 73.74 Cytochrome c oxidase subunit 2Thermus thermophilus 1.20.1070.10 44 4 47 2.10 4.41
1kv4A00 73.68 Moricin-1Bombyx mori 1.20.5.750 42 2 52 2.28 4.35
1tiiC00 73.48 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 13 39 1.41 3.55
1pl5A00 73.43 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 6 38 1.28 3.31
1fdoA05 73.34 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 14 41 1.56 3.78
1dp5B00 73.23 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 12 49 2.38 4.84
1a2xB00 72.93 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 6 39 1.22 3.07
2p7jB01 72.66 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 2 39 1.47 3.70
2gr7A00 72.31 Haemophilus influenzaeAdhesin 3.30.1300.30 101 7 41 1.94 4.67
2hr3A01 71.72 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 10 38 1.44 3.78
1ik7A00 71.37 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 1 34 0.88 2.52
2p1jA02 70.66 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 11 39 1.80 4.54
1vf5C03 70.51 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 9 33 0.75 2.25
1xvhA02 70.46 Extracellular matrix-binding protein ebhStaphylococcus aureus subsp. aureus MW2 1.20.5.420 55 5 33 0.98 2.94
1mqsB00 70.12 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 3 41 1.55 3.76
2p10B02 69.37 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 7 34 1.53 4.38
1nafA01 68.56 ADP-ribosylation factor-binding protein GGA1Homo sapiensProtein bindingIntracellular protein transport 1.20.5.170 36 8 33 1.04 3.12
3c8vA04 67.78 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 0 30 0.78 2.59
2oarA02 67.36 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 26 0.42 1.56
2pp6A01 67.34 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 9 30 0.69 2.29
2rh0A02 65.86 Mus musculusNudC domain-containing protein 2 1.20.5.740 29 6 28 1.24 4.34
2gm6A01 65.02 Ralstonia eutropha JMP134Cysteine dioxygenase type I 1.20.5.440 38 13 30 0.96 3.18
1mslA02 63.97 1.20.5.220 18 16 28 1.17 4.09
2qiwA02 62.39 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 11 28 1.30 4.55
1mkmA02 58.35 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 0 22 0.70 3.15
[1]
Displaying entries 1 to 83 (page 1 of 1)


[top]
Domain ATOM Sequence 

>pdb|1n7sA00
GSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYW
BLAST against CATH

[top]
Domain COMBS Sequence 

>pdb|1n7sA00
GSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYW
BLAST against CATH

[top]
Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"