CATH Domain: 1mz9A00 XML data for domain: 1mz9A00

Molscript image for 1mz9A00
1mz9A00
PDB coordinates for domain 1mz9A00

PDB 1mz9, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.10 Gene3D
1.20.5.10.1
1.20.5.10.1.1
1.20.5.10.1.1.1
1.20.5.10.1.1.1.1
1.20.5.10.1.1.1.1.1

Segment boundaries for domain 1mz9A00

Chopping figure for domain 1mz9A00
DomainStart PDB ResidueStop PDB Residue
1mz9A00 27 71

Structural Neighbourhood (122 entries)

There are 122 matching structural neighberhood comparisons for CATH ID 1.20.5.10.1.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 122 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1czqA00 94.18 1.20.5.170 45 6 95 0.71 0.74
2h8pD00 91.70 1.20.5.110 43 2 86 1.48 1.71
2o1kA00 90.12 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 91 2.07 2.27
1ezjA02 88.85 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 4 86 1.96 2.26
3kpeA00 88.47 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 8 85 2.18 2.56
3effK02 88.39 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 8 97 2.29 2.34
1jekA00 87.62 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 5 80 1.68 2.10
2k9jB00 87.08 Positive regulation of endothelial cell migrationPlatelet-derived growth factor receptor bindingPositive regulation of endothelial cell proliferationActivation of protein kinase activityRegulation of bone resorption 1.20.5.100 43 9 95 2.21 2.31
2basA02 86.98 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 4 97 3.26 3.33
1debB00 86.92 Beta-catenin destruction complexAdenomatous polyposis coli proteinPathways in cancerNegative regulation of microtubule depolymerizationPositive regulation of pseudopodium assembly 1.20.5.10 53 2 84 1.88 2.21
1ifpA00 86.77 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 9 77 1.29 1.66
2qjpB02 86.59 Rhodobacter sphaeroidesCytochrome c1 1.20.5.100 35 11 73 0.93 1.27
1r8eA03 86.54 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 13 80 2.23 2.79
1tiiC00 86.53 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 8 80 2.15 2.69
1gdtB02 86.35 Transposon gamma-delta resolvaseEscherichia coli K-12 1.20.5.40 40 2 88 2.47 2.78
1gmjD00 86.01 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 6 80 2.67 3.32
1gl2A00 85.60 Rattus norvegicusProtein complex assemblyVesicle-associated membrane protein 8Cellular membrane fusionVesicle-associated membrane protein 8 1.20.5.110 53 8 67 1.64 2.41
1kv4A00 85.46 Moricin-1Bombyx mori 1.20.5.750 42 9 93 3.58 3.84
1g2cB00 85.43 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 2 73 2.10 2.86
1ci6A00 85.25 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 6 80 2.61 3.25
1jnmA00 85.20 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 6 80 2.71 3.37
1t3jA00 84.98 Mus musculusMitochondrial fusionMitofusin-1Protein binding 1.20.5.110 62 11 70 1.91 2.69
1junA00 84.60 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 4 82 2.59 3.15
1lghB00 84.11 Phaeospirillum molischianumLight-harvesting protein B-800/850 beta 1 chain 1.20.5.250 43 9 80 3.82 4.78
1j1dB00 83.89 Response to calcium ionTroponin C bindingPositive regulation of ATPase activityActin bindingNegative regulation of ATPase activity 1.20.5.350 70 22 60 1.29 2.15
2e42A00 83.82 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 11 69 2.24 3.24
1kqfB03 83.78 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 2 88 3.63 4.08
1t6aA01 83.72 Geobacillus stearothermophilusRbstp2229 protein 1.20.5.850 43 2 62 1.47 2.36
2b9bA04 83.67 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 15 72 2.32 3.20
1gk4C00 83.54 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 17 64 2.10 3.27
1hf9A00 83.42 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 9 71 1.72 2.42
1uixA00 83.41 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 15 66 1.70 2.57
2p7jB01 83.34 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 0 80 3.54 4.42
1hj0A00 83.32 Bos taurusThymosin beta-10 1.20.5.520 41 2 71 2.60 3.66
2zxeB01 83.27 1.20.5.170 35 2 66 1.73 2.59
1e5wA04 83.27 Leukocyte migrationReceptor bindingCytoskeletonMembrane to membrane dockingNucleolus 1.20.5.450 55 15 74 2.18 2.92
1gl2D00 83.18 Syntaxin-8Rattus norvegicusProtein bindingSyntaxin 8SNARE interactions in vesicular transport 1.20.5.110 54 4 83 3.68 4.42
1a02F00 83.05 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 6 75 2.58 3.42
1pfiA00 83.03 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 4 82 3.07 3.72
1nhlA00 83.01 Vesicle targetingAzurophil granuleCellular membrane fusionSynaptosomal-associated protein 23Protein binding 1.20.5.110 52 11 78 2.83 3.59
1lwuB03 82.96 Fibrinogen beta chainPetromyzon marinus 1.20.5.50 60 2 71 3.25 4.53
1m7lA00 82.62 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 12 88 3.28 3.69
1s3jB01 82.57 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 0 66 1.97 2.96
1dipB01 82.49 Sus scrofaTSC22 domain family protein 3 1.20.5.490 45 17 66 2.04 3.06
2hr3A01 82.40 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 6 66 1.99 2.98
1nwqA00 82.34 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 11 61 1.40 2.27
1jy2O00 82.34 Bos taurusFibrinogen beta chain 1.20.5.50 51 11 62 1.89 3.01
1u57A00 82.30 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 11 68 2.36 3.43
1hgvA00 82.28 Thermus phage PH75Capsid protein G8P 1.20.5.80 46 6 93 2.39 2.56
1rh5B00 82.12 Protein transport protein SEC61 subunit gamma and related proteinsProtein exportMethanocaldococcus jannaschiiPreprotein translocase subunit secE 1.20.5.820 56 4 75 3.56 4.75
1gk6B00 82.10 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 4 71 2.40 3.37
1n2dC00 82.02 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 4 58 1.13 1.94
1lwuC03 81.91 Fibrinogen gamma chainPetromyzon marinus 1.20.5.50 62 2 72 2.69 3.71
1fjkA00 81.85 Calcium signaling pathwayDilated cardiomyopathySus scrofaCardiac phospholambanPhospholamban 1.20.5.290 52 8 75 3.40 4.53
1nknA00 81.77 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 13 60 1.64 2.70
1n7sB00 81.72 Protein domain specific bindingActomyosinMyosin head/neck bindingRattus norvegicusProtein binding, bridging 1.20.5.110 68 2 66 2.56 3.87
1ic2B00 81.58 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 4 58 1.45 2.48
2zjsE00 81.56 Protein exportBacterial secretion systemThermus thermophilus HB8Preprotein translocase subunit secEPreprotein translocase subunit SecE 1.20.5.1030 46 2 69 1.55 2.23
1nkzB00 81.39 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 4 64 2.99 4.64
1urqC00 81.35 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 68 6 66 2.55 3.85
3cx5E01 81.28 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 8 60 1.85 3.08
1jocA01 81.26 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 6 56 1.13 1.99
1gd2F00 81.15 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 6 57 2.06 3.56
2dw3A01 80.88 Intrinsic membrane protein pufXRhodobacter sphaeroides 2.4.1 1.20.5.920 55 6 74 3.07 4.12
1l2pA00 80.80 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 6 52 0.84 1.60
2qjyB02 80.77 Rhodobacter sphaeroidesCytochrome c1 1.20.5.100 35 5 68 2.63 3.82
1fdoA05 80.73 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 7 57 1.52 2.63
1dp5B00 80.64 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 3 57 1.14 1.97
2ifoA00 80.43 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 2 71 2.48 3.46
1owaA01 80.39 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 6 68 2.78 4.04
1go9A00 80.38 1.20.5.480 39 10 64 2.09 3.24
1piqA00 80.34 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 9 53 0.68 1.27
2c0wA00 80.33 Enterobacteria phage fdCapsid protein G8P 1.20.5.80 50 4 64 2.13 3.33
1aq5A00 80.33 Cartilage matrix proteinGallus gallus 1.20.5.30 47 8 57 1.84 3.20
2k1aA00 80.32 Integrin alpha 2BIdentical protein bindingPathways in cancerHematopoietic cell lineageDilated cardiomyopathy 1.20.5.930 42 4 71 2.93 4.12
1ci6B00 80.32 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 2 63 1.94 3.04
1jcdB00 80.26 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 8 51 1.40 2.70
1n7sD00 80.24 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 66 6 68 2.65 3.89
3gg2A02 80.23 Amino sugar and nucleotide sugar metabolismStarch and sucrose metabolismPentose and glucuronate interconversionsSugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase familyUDPglucose 6-dehydrogenase [EC:1.1.1.22] 1.20.5.100 32 3 57 1.56 2.70
1favA00 79.80 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 6 57 2.06 3.57
1ltsC00 79.70 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 4 66 2.32 3.48
1wt6B00 79.67 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 4 67 3.12 4.65
1gl2B00 79.64 Mus musculusSyntaxin-7 1.20.5.110 59 6 52 1.61 3.06
1svfC00 79.52 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 2 61 2.96 4.83
1slqF02 79.35 Outer capsid protein VP4Rhesus rotavirus 1.20.5.170 32 12 66 3.00 4.50
1vpcA00 79.34 HIV-1 M:B_89.6Protein Vpr 1.20.5.90 45 6 73 2.61 3.56
1omiA02 79.16 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 51 0.86 1.68
1a2xB00 78.90 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 16 53 1.58 2.96
2p1jA02 78.80 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 3 57 2.16 3.74
1jthB00 78.63 Protein domain specific bindingMyosin head/neck bindingActomyosinRattus norvegicusProtein heterodimerization activity 1.20.5.110 67 8 50 1.23 2.42
1ozhA03 78.46 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 8 53 1.96 3.67
1afoA00 78.44 Glycophorin-AIdentical protein bindingMembrane fractionPlasma membraneHomo sapiens 1.20.5.70 40 5 51 1.61 3.15
2v4hB00 78.43 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 11 47 1.29 2.73
1vf5C03 78.24 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 3 51 1.75 3.42
1fzcC03 78.02 Fibrinogen gamma chainExternal side of plasma membraneFibrinogen complexEukaryotic cell surface bindingHomo sapiens 1.20.5.50 47 11 63 3.19 5.00
2j58A04 77.99 Putative outer membrane lipoprotein WzaEscherichia coli 1.20.5.70 31 16 64 2.69 4.17
1gl2C00 77.68 Mus musculusVesicle transport through interaction with t-SNAREs homolog 1BGolgi apparatusProtein binding 1.20.5.110 59 4 47 1.53 3.22
1d7mA00 77.49 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 15 44 1.45 3.25
1h8bB00 77.28 TitinOryctolagus cuniculus 1.20.5.510 23 13 51 1.91 3.74
2r44A01 77.00 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 11 57 1.42 2.46
3fwlA01 76.97 Peptidoglycan biosynthesisPenicillin-binding protein 1B [EC:2.4.1.129 3.4.-.-]Penicillin bindingPenicillin-binding protein 1BPeptidoglycan biosynthetic process 1.20.5.100 31 9 62 2.34 3.76
2p1jB02 76.76 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 7 57 2.53 4.38
1kilE00 76.51 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 2 51 2.33 4.56
2p10B02 76.43 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 11 57 2.18 3.77
3b5nJ00 76.41 Cellular membrane fusionSNARE complexPhosphatidylinositol-3,5-bisphosphate bindingSyntaxin 1B/2/3Prospore membrane 1.20.5.110 64 15 51 2.07 4.01
1ybkA00 75.23 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 2 42 1.43 3.38
1wa9B03 74.68 Regulation of circadian sleep/wake cycle, sleepPeriod circadian proteinNucleusResponse to temperature stimulusNegative regulation of transcription from RNA polymerase II promoter 1.20.5.770 33 3 48 1.81 3.70
1m56D00 74.28 Rhodobacter sphaeroidesAa3-type cytochrome c oxidase subunit IV 1.20.5.160 42 4 44 1.82 4.09
3c8vA04 73.64 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 42 0.89 2.11
2pp6A01 73.51 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 4 46 1.75 3.75
2oarA02 73.08 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 17 37 0.92 2.44
2oarE02 72.88 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 9 44 1.53 3.44
2wpqA00 72.82 Salmonella enterica subsp. enterica serovar TyphimuriumPutative inner membrane protein 1.20.5.980 99 6 39 1.45 3.68
1no4C00 71.44 Bacillus phage phi29Head morphogenesis protein 1.20.5.400 73 8 34 1.50 4.38
1fzcB03 70.41 Chaperone bindingSoluble fractionFibrinogen complexEukaryotic cell surface bindingFibrinogen beta chain 1.20.5.50 51 4 49 2.44 4.98
3ii6A02 70.36 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 8 41 1.90 4.59
1fzgA00 69.04 Fibrinogen complexEukaryotic cell surface bindingFibrinogen alpha chainComplement and coagulation cascadesExternal side of plasma membrane 1.20.5.50 66 4 40 1.92 4.69
3hd7B00 68.72 Myosin head/neck bindingActomyosinProtein domain specific bindingRattus norvegicusProtein heterodimerization activity 1.20.5.110 98 0 31 1.38 4.36
1d66B02 67.82 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 6 33 0.49 1.47
2b5uA02 67.48 Colicin-E3Escherichia coli 1.10.287.620 161 8 26 1.33 4.98
1mslA02 66.08 1.20.5.220 18 5 35 1.44 4.05
1mkmA02 65.68 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 7 31 0.68 2.19
Displaying entries 1 to 122 (page 1 of 1)


Domain ATOM Sequence

>pdb|1mz9A00
MDLAPQMLRELQETNAALQDVRELLRQQVKEITFLKNTVMECDAC    

Domain COMBS Sequence

>pdb|1mz9A00
MDLAPQMLRELQETNAALQDVRELLRQQVKEITFLKNTVMECDAC    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:38

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"