CATH Domain: 1mlaA01 XML data for domain: 1mlaA01

Molscript image for 1mlaA01
1mlaA01
PDB coordinates for domain 1mlaA01

PDB 1mla, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.70 Alpha-Beta Plaits
3.30.70.250 Gene3D
3.30.70.250.1
3.30.70.250.1.1
3.30.70.250.1.1.1
3.30.70.250.1.1.1.1
3.30.70.250.1.1.1.1.1

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Segment boundaries for domain 1mlaA01

Chopping figure for domain 1mlaA01
DomainStart PDB ResidueStop PDB Residue
1mlaA01 125 197
1mlaA02 3 124
1mlaA02 198 307

Structural Neighbourhood (78 entries)

There are 78 matching structural neighberhood comparisons for CATH ID 3.30.70.250.1.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 78 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1nm2A01 88.00 Fatty acid biosynthesisStreptomyces coelicolorMalonyl CoA:acyl carrier protein malonyltransferase[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]Metabolic pathways 3.30.70.250 68 26 93 1.93 2.07
1lfpA03 83.43 UPF0082 protein aq_1575Aquifex aeolicus 3.30.70.980 73 5 91 3.09 3.37
1in0A01 83.13 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.860 70 12 83 2.46 2.94
2qmwA03 83.07 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysPrephenate dehydratase [EC:4.2.1.51]Similar to chorismate mutaseStaphylococcus aureus subsp. aureus Mu50 3.30.70.260 73 8 79 2.55 3.21
1vr6A01 82.99 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysThermotoga maritima3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]Phospho-2-dehydro-3-deoxyheptonate aldolase 3.30.70.1140 75 6 84 3.14 3.74
1u8sA01 82.70 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 86 8 76 2.41 3.14
2do0A01 82.62 Protein domain specific bindingIntegral to plasma membraneParaspecklesAlternative nuclear mRNA splicing, via spliceosomeHeterogeneous nuclear ribonucleoprotein M 3.30.70.330 76 10 80 2.53 3.15
1y7pB01 82.40 Archaeoglobus fulgidusUncharacterized protein AF_1403 3.30.70.260 80 6 81 2.62 3.22
2f1fA01 82.32 Valine, leucine and isoleucine biosynthesisMetabolic pathwaysButanoate metabolismC5-Branched dibasic acid metabolismPantothenate and CoA biosynthesis 3.30.70.260 79 5 82 2.70 3.28
1konA03 82.20 UPF0082 protein yebCEscherichia coli K-12 3.30.70.980 75 17 92 3.30 3.59
1j4wA01 81.70 Transcription from RNA polymerase II promoterFar upstream element-binding proteinSequence-specific DNA binding transcription factor activityFar upstream element-binding protein 1Nucleus 3.30.1370.10 74 8 83 3.85 4.60
2nzcA00 81.61 Thermotoga maritimaPutative uncharacterized protein 3.30.70.1150 77 5 85 3.05 3.56
1s99A01 81.61 Bacillus subtilisPutative HMP/thiamine-binding protein ykoF 3.30.70.930 77 10 79 2.64 3.33
1gmuA01 81.53 Klebsiella aerogenesUrease accessory protein ureE 3.30.70.790 67 8 78 3.06 3.92
2fgcA03 81.43 Butanoate metabolismC5-Branched dibasic acid metabolismPantothenate and CoA biosynthesisValine, leucine and isoleucine biosynthesisMetabolic pathways 3.30.70.1150 74 12 86 4.10 4.74
1kn6A00 81.40 Mus musculusPeptide hormone processingSerine-type endopeptidase activityNeuroendocrine convertase 1Proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93] 3.30.70.850 73 5 86 2.74 3.17
1cvjA01 81.26 Poly(A) RNA bindingTranslation activator activityProtein C-terminus bindingMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 77 13 79 2.47 3.12
2nyiA01 81.01 3.30.70.260 77 8 85 3.15 3.67
1s99A02 80.75 Bacillus subtilisPutative HMP/thiamine-binding protein ykoF 3.30.70.930 81 8 75 3.03 4.02
1uv7A00 80.57 Vibrio choleraeGeneral secretion pathway protein M 3.30.1360.100 74 8 77 3.04 3.95
1fxlA02 80.48 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 77 8 76 2.72 3.55
1no8A00 80.38 THO complex subunit 4Mus musculusSpliceosomeSingle-stranded DNA bindingRNA binding 3.30.70.330 78 8 80 3.12 3.86
1l3kA02 80.28 Heterogeneous nuclear ribonucleoprotein A1NucleolusProtein bindingCytoplasmSpliceosome 3.30.70.330 78 6 79 3.00 3.77
1rk8A00 80.27 SpliceosomeRNA-binding protein 8AMicrotubule cytoskeleton organizationNucleusDrosophila melanogaster 3.30.70.330 87 12 80 3.71 4.61
2rhsD06 80.23 Aminoacyl-tRNA biosynthesisStaphylococcus haemolyticus JCSC1435Phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]Phenylalanyl-tRNA synthetase beta chain 3.30.70.380 88 12 71 2.96 4.13
3cj8B02 80.00 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [EC:2.3.1.117]Lysine biosynthesisMetabolic pathwaysEnterococcus faecalis 3.30.70.250 66 12 83 2.77 3.31
2pehA01 79.78 Splicing factor 45SpliceosomeHomo sapiensProtein bindingSplicing factor 45 3.30.70.330 83 8 74 2.84 3.80
1x5uA01 79.65 SpliceosomeSpliceosomal complexHomo sapiensSplicing factor 3B subunit 4Splicing factor 3B subunit 4 3.30.70.330 80 13 80 3.04 3.80
1jqgA01 79.57 Carboxypeptidase AHelicoverpa armigera 3.30.70.340 91 9 74 2.68 3.59
1fxlA01 79.54 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 71 7 78 3.06 3.92
1q5yD00 79.48 CopG family transcriptional regulator, nickel-responsive regulatorNickel-responsive regulatorProtein bindingEscherichia coli K-12 3.30.70.1150 80 12 81 3.13 3.85
2wriY03 79.34 Thermus thermophilus HB8Elongation factor GElongation factor EF-G [EC:3.6.5.3] 3.30.70.870 76 16 89 4.21 4.71
1nu4A00 79.34 U1 small nuclear ribonucleoprotein ASpliceosomeSpliceosomal complexHomo sapiensProtein binding 3.30.70.330 91 9 73 3.02 4.10
1x5oA01 79.11 RNA processingHomo sapiensProtein bindingRNA-binding motif, single-stranded-interacting protein 1 3.30.70.330 86 8 73 2.71 3.70
2qfjA02 79.04 Homo sapiensPoly(U)-binding-splicing factor PUF60Protein binding 3.30.70.330 87 9 73 2.72 3.70
2iboA00 79.01 Streptococcus pneumoniaePutative uncharacterized protein 3.30.70.930 87 8 64 2.74 4.26
2nyiA02 78.81 3.30.70.260 89 5 75 3.32 4.41
2x1fA00 78.78 Protein heterodimerization activityMRNA 3'-end-processing protein RNA15MRNA polyadenylationSaccharomyces cerevisiaeMRNA cleavage 3.30.70.330 94 12 70 2.78 3.96
1zzkA00 78.55 SpliceosomeHeterogeneous nuclear ribonucleoprotein KRNA bindingHeterogeneous nuclear ribonucleoprotein KProtein binding 3.30.1370.10 80 13 75 3.55 4.73
2vooA02 78.18 TRNA modificationNucleolusMRNA bindingProtein bindingLupus La protein 3.30.70.330 89 10 78 3.52 4.48
1pytA00 78.16 Bos taurusCarboxypeptidase A1 [EC:3.4.17.1]Carboxypeptidase A1 3.30.70.340 94 4 74 2.98 4.00
1l6rA02 78.01 Thermoplasma acidophilumPhosphoglycolate phosphatase 3.90.1070.10 63 12 79 3.49 4.39
1jmtA00 77.94 Spliceosomal complexSplicing factor U2AF 35 kDa subunitCajal bodyHomo sapiensProtein binding 3.30.70.330 98 15 64 2.68 4.17
1o8bA02 77.79 Pentose phosphate pathwayMetabolic pathwaysRibose 5-phosphate isomerase A [EC:5.3.1.6]Escherichia coli K-12Ribose-5-phosphate isomerase A 3.30.70.260 69 10 82 3.68 4.48
1d8zA00 77.75 Mus musculusAU-rich element bindingELAV like protein 2/3/4ELAV-like protein 3 3.30.70.330 89 6 76 3.43 4.49
3bv8A00 77.64 Lysine biosynthesisMetabolic pathways2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferaseTetrahydrodipicolinate N-acetyltransferase [EC:2.3.1.89]2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [EC:2.3.1.117] 3.30.70.250 84 8 73 3.01 4.08
1cvjG02 77.63 Poly(A) RNA bindingProtein C-terminus bindingTranslation activator activityMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 88 12 78 3.67 4.68
1eayD00 77.61 Bacterial chemotaxisTwo-component systemTwo-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]Escherichia coli K-12Chemotaxis protein cheA 3.30.70.400 69 8 91 3.91 4.26
1zpvB00 77.43 ACT domain-containing proteinUPF0237 protein SP_0238Streptococcus pneumoniae 3.30.70.260 81 6 79 3.68 4.66
1harA02 77.38 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 69 2 68 3.09 4.51
2hzcA00 77.32 Splicing factor U2AF 65 kDa subunitSpliceosomeSpliceosomal complexSplicing factor U2AF 65 kDa subunitEnzyme binding 3.30.70.330 87 10 79 3.51 4.43
1u0sA00 77.32 Thermotoga maritimaBacterial chemotaxisTwo-component systemTwo-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]Protein binding 3.30.70.1110 86 12 81 3.51 4.31
2epiB00 77.30 Methanocaldococcus jannaschiiUPF0045 protein MJ1052 3.30.70.930 96 6 66 2.97 4.46
1qm9A02 77.23 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexMRNA processingNucleolus 3.30.70.330 89 6 82 3.69 4.50
1u7lA01 77.13 V-type H+-transporting ATPase subunit C [EC:3.6.3.14]Oxidative phosphorylationVacuolar acidificationProtein bindingVacuolar proton-transporting V-type ATPase, V1 domain 3.30.70.1180 91 8 73 3.04 4.13
1s2oA02 77.11 Synechocystis sp. PCC 6803Slr0953 protein 3.90.1070.10 71 4 78 3.09 3.96
1j27A00 77.11 Hypothetical proteinThermus thermophilusPutative uncharacterized protein 3.30.70.1120 98 17 74 3.41 4.58
1mw7A03 76.90 Helicobacter pyloriUPF0082 protein HP_0162 3.30.70.980 75 5 86 3.60 4.15
1uw4A00 76.83 Regulator of nonsense transcripts 3BNuclear-transcribed mRNA catabolic process, nonsense-mediated decayHomo sapiensProtein binding 3.30.70.330 90 9 72 3.11 4.31
3c6kA01 76.66 Spermine synthaseArginine and proline metabolismSpermine synthase [EC:2.5.1.22]Glutathione metabolismMetabolic pathways 3.30.160.110 94 12 67 2.93 4.37
2qmxA03 76.53 Prephenate dehydratase [EC:4.2.1.51]Phenylalanine, tyrosine and tryptophan biosynthesisChlorobaculum tepidumMetabolic pathwaysPrephenate dehydratase 3.30.70.260 90 9 75 3.13 4.14
2bopA00 76.49 Regulatory protein E2Bovine papillomavirus type 1 3.30.70.330 85 8 78 3.28 4.16
3cedA00 76.45 ABC transportersD-methionine transport system ATP-binding proteinMethionine import ATP-binding protein MetN 2Staphylococcus aureus subsp. aureus Mu50 3.30.70.260 97 8 71 2.95 4.15
1ayeA01 76.38 Carboxypeptidase A2 [EC:3.4.17.15]Homo sapiensMetallocarboxypeptidase activityVacuolar protein catabolic processCarboxypeptidase A2 3.30.70.340 99 4 70 3.19 4.51
1ufwA00 76.21 Phosphatidylinositol signaling systemSynaptojanin-2Phosphatidylinositol-bisphosphatase [EC:3.1.3.36]Homo sapiensInositol phosphate metabolism 3.30.70.330 95 8 75 3.76 4.96
1z2lA02 75.95 Purine metabolismZinc ion bindingProtein homodimerization activityAllantoate deiminase [EC:3.5.3.9]Manganese ion binding 3.30.70.360 115 9 60 2.60 4.33
1vk8A00 75.78 Thermotoga maritimaPutative uncharacterized protein 3.30.70.930 91 8 65 3.18 4.82
2w25A02 75.77 Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory proteinLeucine-responsive regulatory proteinMycobacterium tuberculosis 3.30.70.920 81 13 85 3.87 4.54
1u8sA02 75.72 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 84 8 84 3.52 4.16
1in0A02 75.70 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.990 92 13 61 2.81 4.54
1l3kA01 75.35 Heterogeneous nuclear ribonucleoprotein A1NucleolusProtein bindingCytoplasmSpliceosome 3.30.70.330 84 16 79 3.92 4.91
1utaA00 75.16 Membrane fractionCell cycle cytokinesisCell division protein FtsNCell division protein ftsNProtein binding 3.30.70.1070 77 10 85 3.92 4.57
1qm9A01 75.03 Polypyrimidine tract-binding protein 1Poly-pyrimidine tract bindingHeterogeneous nuclear ribonucleoprotein complexNucleolusMRNA processing 3.30.70.330 98 9 68 3.30 4.83
1wj9A01 74.98 Thermus thermophilus HB8Putative uncharacterized protein TTHB192 3.30.70.1200 87 8 73 3.41 4.64
1xmbA02 74.65 Auxin metabolic processArabidopsis thalianaIAA-Ala conjugate hydrolase activityIAA-amino acid hydrolase ILR1-like 2 3.30.70.360 101 16 67 2.96 4.40
2pn6A02 73.75 150aa long hypothetical transcriptional regulatorSulfolobus tokodaii 3.30.70.920 98 5 71 3.30 4.62
2opsB02 73.40 HIV-1 M:B_HXB2RGag-Pol polyprotein 3.30.70.270 49 8 52 2.17 4.17
2od4B01 72.65 3.30.70.900 81 9 77 3.71 4.77
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Displaying entries 1 to 78 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1mlaA01
VPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVS
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1mlaA01
VPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVS
BLAST against CATH

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Domain History Events (4)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "1mla001" to "1mlaA01" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Set cath from cathlist by auto on 05 Mar 2006 18:59

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:59

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:15

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"