CATH Domain: 1l4aA00 XML data for domain: 1l4aA00

Molscript image for 1l4aA00
1l4aA00
PDB coordinates for domain 1l4aA00

PDB 1l4a, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.14
1.20.5.110.14.1
1.20.5.110.14.1.1
1.20.5.110.14.1.1.1
1.20.5.110.14.1.1.1.1

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Segment boundaries for domain 1l4aA00

Chopping figure for domain 1l4aA00
DomainStart PDB ResidueStop PDB Residue
1l4aA00 33 98

Structural Neighbourhood (55 entries)

There are 55 matching structural neighberhood comparisons for CATH ID 1.20.5.110.14.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 55 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1gu4A00 85.26 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 6 96 4.05 4.18
1l2pA00 85.10 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 4 92 3.02 3.27
1jnmA00 84.72 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 12 78 1.74 2.21
1ci6A00 83.91 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 5 84 2.99 3.52
1jcdB00 83.57 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 9 74 2.26 3.04
1ik7A00 81.56 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 5 69 2.72 3.90
1svfC00 81.46 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 9 77 3.06 3.96
1n2dC00 80.72 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 8 71 2.44 3.43
1gd2F00 80.59 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 4 71 2.54 3.57
2basA02 79.90 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 8 69 2.62 3.76
3efgA00 79.76 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 16 74 2.90 3.91
1kilE00 79.66 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 9 62 1.56 2.51
1xmeB01 79.58 Cytochrome c oxidase subunit 2Thermus thermophilus 1.20.1070.10 44 9 59 1.13 1.91
1czqA00 79.20 1.20.5.170 45 8 68 2.39 3.51
1uixA00 78.89 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 9 72 2.69 3.73
1llmD02 78.82 Early growth response protein 1Prion diseasesPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyResponse to insulin stimulusNegative regulation of transcription from RNA polymerase II promoter 3.30.160.60 55 7 62 2.71 4.36
1dh3A00 78.82 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 7 83 3.90 4.68
1ci6B00 78.73 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 8 62 1.74 2.80
2v4hB00 78.41 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 10 65 1.95 2.96
2ifoA00 78.28 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 10 63 2.42 3.80
1xrdA01 77.52 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 11 63 3.05 4.79
1r8eA03 77.45 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 6 66 3.02 4.53
1ic2B00 77.21 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 6 61 2.78 4.55
2zxeB01 75.99 1.20.5.170 35 14 53 2.47 4.66
1favA00 75.96 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 7 61 3.01 4.89
1owaA01 75.90 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 6 48 2.18 4.50
2qjyC01 75.64 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 3 50 1.64 3.28
1d7mA00 75.58 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 7 48 1.52 3.13
1gmjD00 75.47 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 10 46 1.92 4.09
1kv4A00 75.41 Moricin-1Bombyx mori 1.20.5.750 42 9 54 1.94 3.56
1a2xB00 75.12 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 19 46 1.59 3.39
1dp5B00 74.82 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 9 45 1.71 3.76
1ifpA00 74.42 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 4 48 2.14 4.41
3b8eB00 74.01 Sodium/potassium-transporting ATPase subunit beta-1Sus scrofa 1.20.5.170 46 4 63 3.09 4.86
2hr3A01 73.85 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 3 45 1.78 3.92
1omiA02 73.54 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 3 40 0.85 2.08
1fdoA05 73.51 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 7 40 1.71 4.18
1s3jB01 72.88 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 20 45 1.67 3.67
1junA00 72.72 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 6 50 2.34 4.68
1m7lA00 72.62 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 15 51 2.18 4.23
1jekA00 72.56 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 15 39 1.65 4.19
1vf5C03 72.49 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 6 48 1.81 3.73
2r44A01 72.08 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 11 39 0.88 2.23
1jmmA01 71.74 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 12 48 1.97 4.06
1vl2B03 71.12 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 30 3 45 2.21 4.86
1a02F00 70.97 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 5 42 1.87 4.41
1pl5A00 70.94 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 7 42 1.98 4.64
1mqsB00 67.54 Vesicle fusionSyntaxin 5SNAP receptor activityER to Golgi vesicle-mediated transportRetrograde vesicle-mediated transport, Golgi to ER 1.20.5.460 26 3 39 1.88 4.77
2oarE02 67.52 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 4 33 1.41 4.23
1be3K00 67.23 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 13 33 1.19 3.57
3c8vA04 64.42 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 0 28 1.23 4.27
2qiwA02 63.00 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 16 27 0.92 3.37
2oarA02 62.45 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 0 25 0.75 2.91
1d66B02 58.41 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 6 22 0.93 4.09
1mkmA02 55.96 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 7 21 0.67 3.16
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Displaying entries 1 to 55 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1l4aA00
QPVQQSKRLQQTQAQVEEVVDIMRVNVDKVLERDSKISELDDRADALQAGASQFEASAGKLKRKFW
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1l4aA00
PGPPQGPPQPVQQSKRLQQTQAQVEEVVDIMRVNVDKVLERDSKISELDDRADALQAGASQFEASAGKLKRKFWWKNCKM
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"