CATH Domain: 1l2hA00 XML data for domain: 1l2hA00

Molscript image for 1l2hA00
1l2hA00
PDB coordinates for domain 1l2hA00

PDB 1l2h, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.80 Trefoil
2.80.10 Trefoil (Acidic Fibroblast Growth Factor, subunit A)
2.80.10.50 Gene3D
2.80.10.50.6
2.80.10.50.6.1
2.80.10.50.6.1.1
2.80.10.50.6.1.1.1
2.80.10.50.6.1.1.1.1

Segment boundaries for domain 1l2hA00

Chopping figure for domain 1l2hA00
DomainStart PDB ResidueStop PDB Residue
1l2hA00 4 152

Structural Neighbourhood (26 entries)

There are 26 matching structural neighberhood comparisons for CATH ID 2.80.10.50.6.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 26 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1md6A00 87.40 Mus musculusInterleukin-1 family member 5Interleukin 1 family, member 5 (delta) 2.80.10.50 154 27 92 2.82 3.06
2vxtI00 85.54 Cytokine activityInterleukin 18Signal transducer activityInterleukin-18Interferon-gamma biosynthetic process 2.80.10.50 156 15 86 2.65 3.06
1q1uA00 84.76 Pathways in cancerMAPK signaling pathwayMelanomaRegulation of actin cytoskeletonFibroblast growth factor 12 2.80.10.50 138 10 84 2.33 2.75
1upsA02 84.10 Clostridium perfringensGlcNAc-alpha-1,4-Gal-releasing endo-beta-galactosidase 2.80.10.50 133 15 88 2.89 3.28
1n4kA01 82.88 MicrosomeVoluntary musculoskeletal movementNucleolusPhosphoinositide bindingSarcoplasmic reticulum 2.80.10.50 141 7 84 3.13 3.69
1pwaA00 82.47 Negative regulation of bile acid biosynthetic processNervous system developmentPositive regulation of glucose importPathways in cancerPositive regulation of cell proliferation 2.80.10.50 123 12 77 2.65 3.41
1jlxA02 82.41 Amaranthus caudatusAgglutinin 2.80.10.50 140 9 88 3.45 3.88
1dfcA03 82.40 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 11 80 2.70 3.35
1m2tB02 82.02 Beta-galactoside-specific lectin 1Viscum album 2.80.10.50 124 5 81 2.81 3.46
3c9zA02 81.67 Sambucus nigraNigrin b 2.80.10.50 125 6 81 2.89 3.53
1ihkA00 81.52 Pathways in cancerMelanomaMAPK signaling pathwayRegulation of actin cytoskeletonGlia-activating factor 2.80.10.50 157 12 78 2.74 3.50
1vclA02 81.47 Cucumaria echinataHemolytic lectin CEL-III 2.80.10.50 134 9 84 3.11 3.67
1wd3A02 81.45 Alpha-L-arabinofuranosidase BAspergillus awamori 2.80.10.50 162 8 79 3.38 4.28
1dfcA02 81.43 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 123 9 79 2.75 3.44
3c9zA01 81.01 Sambucus nigraNigrin b 2.80.10.50 130 5 83 3.66 4.39
1dfcA01 80.80 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 122 9 79 2.79 3.49
1w3fA01 80.77 Laetiporus sulphureusHemolytic lectin LSLa 2.80.10.50 147 9 86 3.22 3.73
1sr4A00 80.54 Haemophilus ducreyiCytolethal distending toxin subunit ACytolethal distending toxin subunit A 2.80.10.50 167 9 76 3.25 4.24
1jlxA01 80.54 Amaranthus caudatusAgglutinin 2.80.10.50 159 11 81 3.17 3.91
1vclA01 80.18 Cucumaria echinataHemolytic lectin CEL-III 2.80.10.50 149 5 84 3.43 4.06
1t9fA00 79.85 Caenorhabditis elegansPutative uncharacterized protein 2.80.10.50 178 7 75 3.19 4.24
1dqgA00 79.35 Mus musculusMacrophage mannose receptor 1Mannose bindingCell surfaceTransmembrane receptor activity 2.80.10.50 134 8 83 3.93 4.72
3iagC02 79.33 Transcription factor bindingHeart developmentRegulation of timing of cell differentiationDefense response to bacteriumNotch signaling pathway 2.80.10.50 155 10 65 2.79 4.24
1dfcA04 79.10 FascinActin cytoskeletonActin filament bundle assemblyHomo sapiensCell proliferation 2.80.10.50 107 10 70 2.65 3.74
1hcdA00 78.40 Membrane fractionPlasma membraneActin filament bindingHisactophilin-1Cytosol 2.80.10.50 118 17 80 3.31 4.11
2qn4A00 78.35 Oryza sativa Japonica GroupAlpha-amylase inhibitor activityAlpha-amylase/subtilisin inhibitorSerine-type endopeptidase inhibitor activity 2.80.10.50 159 5 77 3.47 4.45
Displaying entries 1 to 26 (page 1 of 1)


Domain ATOM Sequence

>pdb|1l2hA00
RSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVWSMSFVQGEESNKIPVALGLKEKNLYLSCVLKDDKPTLQLES
VDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNFYISTSQAENMPVFLGGQDITDFTMQFVS    

Domain COMBS Sequence

>pdb|1l2hA00
APVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVWSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTL
QLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNFYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:48

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:09

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"