CATH Domain: 1k5nB00 XML data for domain: 1k5nB00

Molscript image for 1k5nB00
1k5nB00
PDB coordinates for domain 1k5nB00

PDB 1k5n, Chain B, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.2
2.60.40.10.2.1
2.60.40.10.2.1.1
2.60.40.10.2.1.1.1
2.60.40.10.2.1.1.1.1

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Segment boundaries for domain 1k5nB00

Chopping figure for domain 1k5nB00
DomainStart PDB ResidueStop PDB Residue
1k5nB00 0 99

Structural Neighbourhood (93 entries)

There are 93 matching structural neighberhood comparisons for CATH ID 2.60.40.10.2.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 93 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1uvqA02 92.24 2.60.40.10 99 28 98 1.16 1.18
1fv1B02 91.02 HLA class II histocompatibility antigen, DR beta 5 chainMajor histocompatibility complex, class IIType I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA production 2.60.40.10 98 30 97 2.76 2.85
3dbxA02 90.86 CD1-2 antigenGallus gallus 2.60.40.10 99 24 95 2.45 2.58
1k5nA02 89.13 HLA class I histocompatibility antigen, B-27 alpha chainMembrane fractionDefense responseHomo sapiens 2.60.40.10 95 23 94 2.25 2.39
3g08A02 88.83 Antigen-presenting glycoprotein CD1d1Endogenous lipid antigen bindingPositive thymic T cell selectionAntigen processing and presentation, exogenous lipid antigen via MHC class IbProtein binding 2.60.40.10 88 28 87 1.78 2.05
3fruA02 88.61 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 26 92 2.58 2.80
1t7vA02 88.38 Cell adhesionHomo sapiensZinc-alpha-2-glycoprotein 2.60.40.10 90 25 90 2.75 3.06
1l6xA02 88.25 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 106 22 92 2.31 2.50
2bc4D02 88.04 Major histocompatibility complex, class IIType I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejection 2.60.40.10 107 27 92 3.69 3.99
3d9aL02 88.00 2.60.40.10 102 17 94 2.56 2.72
2bc4A02 87.98 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 27 91 2.32 2.53
1ow0A02 87.59 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 109 18 89 1.98 2.20
3h9yA02 87.52 Homo sapiensIg epsilon chain C region 2.60.40.10 108 21 90 2.72 3.00
1je6A02 87.29 Response to heatMHC class I polypeptide-related sequence BGamma-delta T cell activationImmune response-activating cell surface receptor signaling pathwayResponse to retinoic acid 2.60.40.10 89 14 87 2.11 2.43
1q0xL02 87.14 Mus musculusIg lambda-1 chain V regionProtein binding 2.60.40.10 100 15 95 2.58 2.72
1l6xA01 86.95 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 100 11 92 2.06 2.24
1u58A02 86.63 Murine cytomegalovirus (strain K181)Immunoevasin 2.60.40.10 100 19 94 2.69 2.86
1seqH02 86.14 Rattus norvegicusIghg protein 2.60.40.10 98 14 95 2.41 2.54
2vxvH02 85.98 2.60.40.10 101 14 96 2.45 2.55
1ncwH02 85.95 2.60.40.10 99 16 95 2.45 2.58
3d9aH02 85.71 2.60.40.10 97 15 93 2.56 2.75
1o0vA01 85.49 Homo sapiensIg epsilon chain C region 2.60.40.10 102 14 92 2.66 2.89
1hxmB02 85.48 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 11 92 2.78 3.01
1dn0D02 85.48 2.60.40.10 94 12 88 1.86 2.11
3h9yB01 84.84 Homo sapiensIg epsilon chain C region 2.60.40.10 101 13 92 2.82 3.06
1mcpH02 84.48 Mus musculusIg heavy chain V region M603 2.60.40.10 99 14 95 3.37 3.55
1q72H02 84.10 2.60.40.10 89 15 86 2.32 2.70
1hxmA02 83.82 2.60.40.10 85 15 85 3.29 3.87
1ow0A01 82.93 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 100 7 92 3.03 3.29
2bnuB02 82.72 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 126 19 77 2.85 3.66
1zxqA02 82.26 Intercellular adhesion molecule 2Integral to plasma membraneIntercellular adhesion molecule 2Natural killer cell mediated cytotoxicityHomo sapiens 2.60.40.10 107 11 85 3.48 4.09
1vcaA02 82.08 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationMembrane to membrane dockingLeukocyte transendothelial migration 2.60.40.10 110 17 87 4.18 4.79
1p53A01 81.95 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 98 12 91 3.69 4.05
2ec8A03 81.92 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 8 91 3.92 4.29
1iamA02 81.83 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 102 13 88 3.90 4.42
1ex0A04 80.98 Protein-glutamine gamma-glutamyltransferase activityHomo sapiensCoagulation factor XIII A chainBlood coagulation 2.60.40.10 95 9 89 3.87 4.35
1g1cA00 80.94 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 13 86 3.95 4.59
2rikA01 80.74 TitinOryctolagus cuniculus 2.60.40.10 96 13 85 3.94 4.64
2ec8A04 80.71 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 9 92 4.15 4.51
2rikA02 80.63 TitinOryctolagus cuniculus 2.60.40.10 95 10 80 3.97 4.96
1dr9A02 80.52 Type I diabetes mellitusIntestinal immune network for IgA productionAutoimmune thyroid diseaseAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 95 15 94 4.43 4.71
2j8hA01 80.51 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 12 84 3.64 4.33
2a38B01 80.51 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 12 86 3.66 4.26
2bk8A00 80.34 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 10 84 3.83 4.56
2gy5A04 80.21 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 17 90 3.91 4.34
1vjjA04 80.19 Calcium ion bindingHair follicle morphogenesisGTP bindingExtrinsic to internal side of plasma membraneTransglutaminase 3 [EC:2.3.2.13] 2.60.40.10 97 7 91 4.20 4.62
2v44A01 80.13 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 12 83 3.90 4.70
1fhgA00 80.09 TelokinMeleagris gallopavo 2.60.40.10 102 11 85 3.79 4.44
2c5dC01 80.04 Integral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiensTyrosine-protein kinase receptor UFOSignal transduction 2.60.40.10 104 13 89 4.15 4.64
2fbjH02 79.82 Mus musculusIg heavy chain V region J539 2.60.40.10 73 13 72 3.57 4.96
1itbB03 79.80 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 112 13 85 4.02 4.69
1iamA01 79.51 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 83 12 80 3.96 4.95
2ec8A05 79.42 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 81 9 80 3.04 3.80
1cczA02 79.34 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 78 12 75 3.15 4.20
1g0dA04 79.32 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 97 10 91 4.15 4.56
2gy5A01 79.31 Cell surfaceMicrovillusIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transduction 2.60.40.10 99 9 86 4.06 4.72
1gsmA02 79.23 Membrane fractionMucosal vascular addressin cell adhesion molecule 1Intestinal immune network for IgA productionCell adhesionHomo sapiens 2.60.40.10 116 11 82 3.69 4.46
3b43A02 79.20 TitinOryctolagus cuniculus 2.60.40.10 97 10 86 3.82 4.44
1cs6A03 79.20 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 7 80 3.98 4.97
1cs6A04 79.06 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 12 78 3.84 4.92
2ifgA02 78.76 High affinity nerve growth factor receptorIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiens 2.60.40.10 90 7 82 3.30 4.02
1cwvA02 78.57 InvasinYersinia pseudotuberculosis 2.60.40.920 97 7 82 4.02 4.90
1g0dA03 78.37 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 110 5 79 3.74 4.73
1koaA03 78.06 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 14 84 3.73 4.44
1rhfA02 77.91 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 84 7 82 3.70 4.51
1cidA02 77.89 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 71 14 70 3.21 4.59
1f97A02 77.71 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 105 12 80 3.96 4.95
2dm2A00 77.70 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 10 79 3.67 4.64
1f00I01 77.66 Pathogenic Escherichia coli infectionIntiminIntiminProtein bindingEscherichia coli O127:H6 str. E2348/69 2.60.40.920 95 10 83 3.99 4.81
1eerC01 77.57 Jak-STAT signaling pathwayIntegral to plasma membraneHematopoietic cell lineageErythropoietin receptor activityErythropoietin receptor 2.60.40.10 97 5 88 3.99 4.53
3hn3A02 77.56 Beta-glucuronidaseGlycosaminoglycan degradationGlycosaminoglycan catabolic processMetabolic pathwaysStarch and sucrose metabolism 2.60.40.320 103 12 81 3.95 4.84
1iilG02 77.54 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 107 11 74 3.24 4.33
2rikA03 77.53 TitinOryctolagus cuniculus 2.60.40.10 92 10 82 3.84 4.68
1mh5B02 77.42 2.60.40.10 52 15 52 1.34 2.58
1jz7A02 77.27 Galactose metabolismSphingolipid metabolismOther glycan degradationMetabolic pathwaysLactose catabolic process 2.60.40.320 114 9 81 3.76 4.61
2ialA01 77.26 Homo sapiensT-cell receptor alpha chain C region 2.60.40.10 108 7 77 3.71 4.77
1waaC00 77.18 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 5 81 3.99 4.93
1dceA02 77.07 Rattus norvegicusRab geranylgeranyltransferase activityProtein geranylgeranyltransferase type II [EC:2.5.1.60]Geranylgeranyl transferase type-2 subunit alpha 2.60.40.1130 103 5 79 3.84 4.82
2fcbA02 77.01 Low affinity immunoglobulin gamma Fc region receptor II-bHomo sapiensImmune responseSignal transduction 2.60.40.10 87 11 78 3.85 4.94
1f2qA02 76.86 High affinity immunoglobulin epsilon receptor subunit alphaIntegral to plasma membraneHomo sapiensFc receptor, IgE, high affinity I, alpha polypeptideAsthma 2.60.40.10 90 13 79 3.88 4.91
1t0pB00 76.67 Integral to plasma membraneIntercellular adhesion molecule 3Homo sapiensIntercellular adhesion molecule 3Cell adhesion molecules (CAMs) 2.60.40.10 86 4 80 3.50 4.38
1bquA01 76.41 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 7 82 4.07 4.96
1cfbA02 76.27 Calcium ion bindingNeuron cell-cell adhesionDrosophila melanogasterNerve maturationEpidermal growth factor receptor signaling pathway 2.60.40.10 106 9 80 3.84 4.79
3b4nA01 76.23 Erwinia chrysanthemiEndo-pectate lyase 2.60.40.10 88 10 79 3.74 4.73
1ok8A04 75.81 Dengue virus 2 Puerto Rico/PR159-S1/1969Genome polyprotein 2.60.40.350 100 4 85 3.90 4.59
2gysA03 75.73 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaApoptosis 2.60.40.10 86 6 74 3.36 4.54
2ny1B02 75.67 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 75 9 73 3.53 4.84
1ej6A05 75.62 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 8 83 3.81 4.59
1im3D00 75.46 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 13 89 4.33 4.87
1cvrA03 75.35 Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2 2.60.40.10 83 6 80 3.53 4.41
1eh9A03 74.45 Sulfolobus solfataricusMalto-oligosyltrehalose trehalohydrolase 2.60.40.10 87 4 73 3.35 4.59
1fnfA02 73.95 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 87 1 77 3.74 4.86
1fnhA03 73.09 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 13 84 4.02 4.79
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Displaying entries 1 to 93 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1k5nB00
MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA
CRVNHVTLSQPKIVKWDRDM
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1k5nB00
MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA
CRVNHVTLSQPKIVKWDRDM
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:34

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:34

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:57

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"