CATH Domain: 1k5nA02 XML data for domain: 1k5nA02

Molscript image for 1k5nA02
1k5nA02
PDB coordinates for domain 1k5nA02

PDB 1k5n, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.7
2.60.40.10.7.1
2.60.40.10.7.1.1
2.60.40.10.7.1.1.1
2.60.40.10.7.1.1.1.1

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Segment boundaries for domain 1k5nA02

Chopping figure for domain 1k5nA02
DomainStart PDB ResidueStop PDB Residue
1k5nA01 1 181
1k5nA02 182 276

Structural Neighbourhood (96 entries)

There are 96 matching structural neighberhood comparisons for CATH ID 2.60.40.10.7.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 96 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1t7vA02 91.40 Cell adhesionHomo sapiensZinc-alpha-2-glycoprotein 2.60.40.10 90 37 92 1.73 1.87
1je6A02 91.16 Response to heatMHC class I polypeptide-related sequence BGamma-delta T cell activationImmune response-activating cell surface receptor signaling pathwayResponse to retinoic acid 2.60.40.10 89 37 92 1.34 1.45
1u58A02 90.92 Murine cytomegalovirus (strain K181)Immunoevasin 2.60.40.10 100 27 93 1.37 1.47
3fruA02 90.54 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 33 95 1.72 1.80
3g08A02 90.47 Antigen-presenting glycoprotein CD1d1Endogenous lipid antigen bindingPositive thymic T cell selectionAntigen processing and presentation, exogenous lipid antigen via MHC class IbProtein binding 2.60.40.10 88 31 90 1.40 1.55
1fv1B02 90.30 HLA class II histocompatibility antigen, DR beta 5 chainMajor histocompatibility complex, class IIType I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA production 2.60.40.10 98 28 96 1.86 1.92
3dbxA02 90.20 CD1-2 antigenGallus gallus 2.60.40.10 99 28 95 1.95 2.03
1uvqA02 89.39 2.60.40.10 99 25 95 2.06 2.15
1l6xA02 88.37 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 106 18 88 1.85 2.09
1ow0A02 87.66 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 109 21 87 1.94 2.23
1seqH02 87.52 Rattus norvegicusIghg protein 2.60.40.10 98 20 93 2.25 2.40
3h9yA02 87.35 Homo sapiensIg epsilon chain C region 2.60.40.10 108 17 87 1.97 2.24
1q0xL02 87.30 Mus musculusIg lambda-1 chain V regionProtein binding 2.60.40.10 100 22 92 2.38 2.59
3d9aH02 87.26 2.60.40.10 97 18 92 2.02 2.18
1l6xA01 87.11 Ig gamma-1 chain C regionHomo sapiensProtein bindingAntigen binding 2.60.40.10 100 14 90 2.31 2.57
1ncwH02 86.91 2.60.40.10 99 20 92 2.15 2.31
1dn0D02 86.90 2.60.40.10 94 19 90 2.32 2.56
2bc4D02 86.73 Major histocompatibility complex, class IIType I diabetes mellitusAutoimmune thyroid diseaseIntestinal immune network for IgA productionAllograft rejection 2.60.40.10 107 31 88 3.04 3.42
1o0vA01 86.25 Homo sapiensIg epsilon chain C region 2.60.40.10 102 17 89 2.56 2.87
2vxvH02 86.23 2.60.40.10 101 20 92 2.34 2.54
1hxmB02 86.00 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 17 85 1.92 2.24
1q72H02 85.80 2.60.40.10 89 20 87 2.30 2.63
1hxmA02 84.97 2.60.40.10 85 14 87 3.16 3.62
1mcpH02 84.70 Mus musculusIg heavy chain V region M603 2.60.40.10 99 17 92 2.89 3.11
1dr9A02 84.51 Type I diabetes mellitusIntestinal immune network for IgA productionAutoimmune thyroid diseaseAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 95 14 95 2.82 2.94
3h9yB01 84.24 Homo sapiensIg epsilon chain C region 2.60.40.10 101 16 91 2.75 3.02
2bc4A02 83.51 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 17 86 2.86 3.32
2bnuB02 82.99 T-cell receptor beta-1 chain C regionHomo sapiensProtein binding 2.60.40.10 126 23 75 2.56 3.40
1ow0A01 82.53 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 100 15 91 3.05 3.35
2ec8A03 82.07 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Acute myeloid leukemiaProtein binding 2.60.40.10 104 12 87 3.50 4.00
2rikA01 81.28 TitinOryctolagus cuniculus 2.60.40.10 96 17 84 3.39 4.02
2fbjH02 81.22 Mus musculusIg heavy chain V region J539 2.60.40.10 73 15 69 2.61 3.76
2v44A01 81.21 Prion diseasesNeural cell adhesion moleculeNeuron cell-cell adhesionPlasma membraneNeural cell adhesion molecule 2 2.60.40.10 94 9 84 3.66 4.35
1vcaA02 80.69 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationMembrane to membrane dockingLeukocyte transendothelial migration 2.60.40.10 110 11 82 4.01 4.85
1itbB03 80.54 Platelet-derived growth factor receptor bindingIntegral to plasma membraneHematopoietic cell lineageInterleukin 1 receptor, type IInterleukin-1-mediated signaling pathway 2.60.40.10 112 9 80 3.52 4.38
2ec8A04 80.45 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 100 9 89 3.53 3.97
1vcaA01 80.40 Vascular cell adhesion protein 1MicrovillusPositive regulation of T cell proliferationHeterophilic cell-cell adhesionFilopodium 2.60.40.10 89 13 82 3.83 4.66
2bk8A00 80.37 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 97 9 82 3.40 4.12
1zxqA02 79.98 Intercellular adhesion molecule 2Integral to plasma membraneIntercellular adhesion molecule 2Natural killer cell mediated cytotoxicityHomo sapiens 2.60.40.10 107 13 85 4.09 4.81
1cczA02 79.89 Homo sapiensLymphocyte function-associated antigen 3Protein binding 2.60.40.10 78 14 77 2.85 3.66
2gy5A01 79.75 Cell surfaceMicrovillusIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transduction 2.60.40.10 99 18 83 4.00 4.77
1koaA03 79.73 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 8 85 3.46 4.05
1iamA02 79.65 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 102 14 84 4.09 4.85
2c5dC01 79.62 Integral to plasma membraneTransmembrane receptor protein tyrosine kinase activityHomo sapiensTyrosine-protein kinase receptor UFOSignal transduction 2.60.40.10 104 14 86 3.93 4.54
2j8hA02 79.59 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 10 79 3.35 4.21
1t0pB00 79.42 Integral to plasma membraneIntercellular adhesion molecule 3Homo sapiensIntercellular adhesion molecule 3Cell adhesion molecules (CAMs) 2.60.40.10 86 11 81 3.80 4.69
1g1cA00 79.39 Structural constituent of muscleCalcium ion bindingTelethonin bindingSarcomere organizationActin filament binding 2.60.40.10 98 7 84 3.57 4.22
1qz1A03 79.28 Rattus norvegicusPrion diseasesNeural cell adhesion moleculePlasma membraneFibroblast growth factor receptor binding 2.60.40.10 95 15 81 3.92 4.84
2ec8A05 79.22 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 81 8 83 3.21 3.86
2rikA03 79.21 TitinOryctolagus cuniculus 2.60.40.10 92 8 84 3.70 4.39
3b43A02 79.14 TitinOryctolagus cuniculus 2.60.40.10 97 12 85 3.45 4.03
1mh5B02 79.10 2.60.40.10 52 21 52 1.25 2.38
2rikA02 78.91 TitinOryctolagus cuniculus 2.60.40.10 95 10 87 3.93 4.50
1cs6A04 78.88 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 90 12 80 3.47 4.34
2gy5A04 78.83 MicrovillusCell surfaceTransmembrane receptor protein tyrosine kinase signaling pathwaySignal transductionProtein binding 2.60.40.10 99 11 86 3.62 4.17
1rhfA02 78.80 Integral to plasma membraneTyrosine-protein kinase receptor TYRO3Cell adhesionTYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]Signal transduction 2.60.40.10 84 14 82 4.05 4.93
1cs6A03 78.59 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 98 16 80 3.80 4.71
2a38B01 78.57 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 99 14 81 3.44 4.20
1bihA04 78.16 Hyalophora cecropiaHemolin 2.60.40.10 88 11 78 3.83 4.85
2j8hA01 78.15 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 97 11 86 3.42 3.95
1eerC01 77.96 Jak-STAT signaling pathwayIntegral to plasma membraneHematopoietic cell lineageErythropoietin receptor activityErythropoietin receptor 2.60.40.10 97 9 88 4.27 4.82
2rb8A00 77.72 TenascinCell adhesionSyndecan bindingECM-receptor interactionTenascin 2.60.40.10 93 9 84 4.00 4.75
1fhgA00 77.70 TelokinMeleagris gallopavo 2.60.40.10 102 11 82 3.67 4.46
2cqvA00 77.54 Myosin light chain kinase activityProtein phosphorylationHomo sapiensMyosin light chain kinase, smooth muscle 2.60.40.10 114 10 71 3.47 4.88
1gl4B00 77.46 Chondrocyte differentiationCardiac muscle tissue developmentCartilage development involved in endochondral bone morphogenesisProtein localizationBrain development 2.60.40.10 89 13 81 3.88 4.79
1cidA02 77.46 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 71 16 74 3.37 4.51
3cafA01 77.38 Cell surfacePathways in cancerNucleusPositive regulation of cell proliferationFibroblast growth factor binding 2.60.40.10 96 16 83 4.03 4.84
1bihA03 77.36 Hyalophora cecropiaHemolin 2.60.40.10 100 12 83 3.92 4.72
2fnbA00 77.31 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 95 9 84 3.77 4.48
1f97A02 77.17 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 105 11 77 3.61 4.68
1cs6A02 77.04 Cell adhesion molecule bindingContactin 2Neuron cell-cell adhesionGallus gallusContactin-2 2.60.40.10 89 12 77 3.64 4.67
2nqcA00 76.99 Plasma membraneFilamin-CHomo sapiens 2.60.40.10 97 4 83 3.80 4.55
3bfoA00 76.98 T cell receptor signaling pathwayPositive regulation of T cell cytokine productionActivation of NF-kappaB-inducing kinase activityPositive regulation of interleukin-2 productionNucleus 2.60.40.10 85 15 80 3.67 4.59
1iarB01 76.95 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneInterleukin-4 receptor activityHematopoietic cell lineage 2.60.40.10 96 4 82 3.82 4.64
1cvrA03 76.93 Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2 2.60.40.10 83 7 85 3.93 4.61
2v44A02 76.87 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 93 7 85 3.87 4.54
2qfpA01 76.86 Fe(3+)-Zn(2+) purple acid phosphatasePhaseolus vulgaris 2.60.40.380 97 7 87 3.70 4.22
1waaC00 76.76 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 93 8 82 3.95 4.81
1fnfA03 76.74 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 5 85 4.26 5.00
1pewA00 76.73 Ig lambda chain V-VI region SUTHomo sapiens 2.60.40.10 108 8 76 3.74 4.87
1ti6B03 76.62 Pelobacter acidigalliciPyrogallol hydroxytransferase small subunit 2.60.40.10 84 8 71 3.55 4.96
1l6zA02 76.42 Mus musculusCarcinoembryonic antigen-related cell adhesion molecule 1 2.60.40.10 96 8 83 4.08 4.90
1f97A01 76.41 Mus musculusEpithelial cell differentiationJunctional adhesion molecule ACell adhesionTight junction 2.60.40.10 102 12 78 3.73 4.76
1vjjA04 76.31 Calcium ion bindingHair follicle morphogenesisGTP bindingExtrinsic to internal side of plasma membraneTransglutaminase 3 [EC:2.3.2.13] 2.60.40.10 97 1 91 4.33 4.72
3b4nA01 76.19 Erwinia chrysanthemiEndo-pectate lyase 2.60.40.10 88 10 78 3.90 4.94
2dm2A00 76.15 NucleusHomo sapiensPalladinActin filamentMuscle alpha-actinin binding 2.60.40.10 110 9 76 3.63 4.75
1nctA00 76.05 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 98 10 82 4.02 4.86
3hn3A02 75.89 Beta-glucuronidaseGlycosaminoglycan degradationGlycosaminoglycan catabolic processMetabolic pathwaysStarch and sucrose metabolism 2.60.40.320 103 10 80 3.77 4.68
1im3D00 75.40 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 8 90 3.84 4.24
2ny1B02 75.25 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 75 8 77 3.87 4.97
1w8oA02 74.96 Micromonospora viridifaciensSialidase 2.60.40.10 102 4 86 4.28 4.96
1eh9A03 74.93 Sulfolobus solfataricusMalto-oligosyltrehalose trehalohydrolase 2.60.40.10 87 4 76 3.42 4.45
1svbA04 74.88 Genome polyproteinTick-borne encephalitis virus (WESTERN SUBTYPE) 2.60.40.350 96 11 82 3.87 4.70
1fnhA01 74.85 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 6 86 4.31 4.99
1bquA01 74.84 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 6 82 3.66 4.46
1cfbA02 73.69 Calcium ion bindingNeuron cell-cell adhesionDrosophila melanogasterNerve maturationEpidermal growth factor receptor signaling pathway 2.60.40.10 106 10 78 3.89 4.97
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Displaying entries 1 to 96 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1k5nA02
ADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHV
QHEGLPKPLTLRWEP
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1k5nA02
ADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHV
QHEGLPKPLTLRWEP
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:34

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:34

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 17:01

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"