CATH Domain: 1jo8A00 XML data for domain: 1jo8A00

Molscript image for 1jo8A00
1jo8A00
PDB coordinates for domain 1jo8A00

PDB 1jo8, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.11
2.30.30.40.11.1
2.30.30.40.11.1.1
2.30.30.40.11.1.1.1
2.30.30.40.11.1.1.1.1

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Segment boundaries for domain 1jo8A00

Chopping figure for domain 1jo8A00
DomainStart PDB ResidueStop PDB Residue
1jo8A00 1 58

Structural Neighbourhood (74 entries)

There are 74 matching structural neighberhood comparisons for CATH ID 2.30.30.40.11.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 74 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3i35A00 94.55 Focal adhesionHomo sapiensLIM and SH3 domain protein 1SH3/SH2 adaptor activity 2.30.30.40 56 39 96 0.71 0.74
2j6fA00 94.22 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 38 96 0.81 0.84
1ckaA00 93.39 Pathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayFc gamma R-mediated phagocytosisErbB signaling pathway 2.30.30.40 56 23 94 1.06 1.12
2vwfA00 93.04 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 39 96 0.97 1.00
1w70A00 92.17 Protein dimerization activityLeukocyte transendothelial migrationNeutrophil cytosolic factor 4CytosolNADPH oxidase complex 2.30.30.40 60 27 93 1.05 1.12
3i9qA00 91.74 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 57 28 96 1.13 1.17
1yn8A00 91.73 NucleusHyperosmotic responseResponse to heatNegative regulation of protein kinase activityProtein binding 2.30.30.40 59 31 98 1.42 1.44
1ov3A02 91.71 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 29 93 1.21 1.30
3h0hA00 91.68 T cell receptor signaling pathwayLearningPrion diseasesFeeding behaviorTyrosine-protein kinase Fyn 2.30.30.40 63 31 92 1.17 1.27
2ak5B00 91.56 Rattus norvegicusFocal adhesionProtein bindingGrowth coneCytoplasm 2.30.30.40 64 29 87 1.40 1.60
2rqtA00 91.15 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 36 95 1.58 1.66
1ad5A01 91.02 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 27 90 1.10 1.22
1zuyA00 90.62 Identical protein bindingMating projection tipReceptor-mediated endocytosisActin cortical patch localizationResponse to salt stress 2.30.30.40 58 25 98 1.53 1.56
1x6bA01 90.22 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 24 89 1.46 1.64
1griA01 90.05 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 37 82 0.93 1.12
2jteA00 90.03 Mus musculusCD2-associated protein 2.30.30.40 64 31 87 1.02 1.17
1jegA00 89.86 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 22 95 1.40 1.47
2v1rA00 89.70 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 27 83 1.10 1.32
3ehrB01 89.56 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 32 88 1.57 1.77
2vknA00 89.23 MAPK signaling pathway - yeastIdentical protein bindingMating projection tipPseudohyphal growthOsmosensor activity 2.30.30.40 66 32 84 1.61 1.90
1wx6A01 89.07 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 27 86 1.60 1.85
1ycsB02 88.36 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 27 85 1.41 1.64
2ablA01 88.03 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 66 25 84 1.54 1.81
1ng2A02 87.82 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 68 27 79 1.36 1.71
2csqA01 87.76 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 32 84 1.51 1.78
1gcqC00 87.71 Integrin-mediated signaling pathwayProto-oncogene vavProtein bindingMus musculusT cell differentiation 2.30.30.40 69 20 84 2.05 2.44
2js2A00 87.67 Receptor bindingNCK adaptor proteinPositive regulation of T cell proliferationT cell receptor signaling pathwayPositive regulation of actin filament polymerization 2.30.30.40 63 27 88 1.92 2.16
1spkA00 87.08 Mus musculusBrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2.30.30.40 72 24 80 1.54 1.91
1awwA00 86.94 Phosphatidylinositol-3,4,5-trisphosphate bindingInduction of apoptosis by extracellular signalsIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.30.40 67 31 85 1.47 1.73
1uhfA00 86.63 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 69 32 79 1.34 1.68
1j3tA00 86.63 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 74 34 72 1.21 1.66
2ke9A00 86.30 Caskin-2Homo sapiens 2.30.30.40 67 22 86 2.08 2.40
1bb9A00 85.92 Rattus norvegicusProtein heterodimerization activityProtein C-terminus bindingSynaptic vesicle endocytosisMyc box-dependent-interacting protein 1 2.30.30.40 83 31 69 1.61 2.30
1ng2A01 85.51 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 18 72 1.55 2.14
2epdA00 85.10 Rho protein signal transductionCytoskeleton organizationRho GTPase-activating protein 4Homo sapiensRho GTPase activator activity 2.30.30.40 76 32 73 1.66 2.25
3i5rA00 84.91 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 2.30.30.40 81 25 71 2.16 3.02
1sf9A02 84.11 Bacillus subtilisUncharacterized protein yfhH 2.30.30.340 54 7 75 1.47 1.94
1u3oA01 83.30 Rattus norvegicusVesicle-mediated transportProtein bindingAxonogenesisNeuron projection 2.30.30.40 62 18 87 2.49 2.86
2heqA01 83.00 Bacillus subtilisSPBc2 prophage-derived uncharacterized protein yorP 2.30.30.40 54 11 89 2.78 3.10
1igqB00 82.68 Escherichia coliTranscriptional repressor protein korB 2.30.30.150 57 10 74 2.10 2.83
1tucA00 82.60 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 61 18 73 3.66 4.96
1jxmA01 82.04 Postsynaptic membraneRattus norvegicusProtein C-terminus bindingIonotropic glutamate receptor bindingDisks large homolog 4 2.30.30.40 80 22 66 2.44 3.68
2rh2A00 81.80 Dihydrofolate reductase type 2Escherichia coli 2.30.30.60 57 10 77 2.15 2.77
2g3rA01 81.65 CytoplasmHomo sapiensTumor suppressor p53-binding protein 1Protein binding 2.30.30.140 53 9 81 2.38 2.94
2aklA02 81.50 Phosphonate and phosphinate metabolismPseudomonas aeruginosaPhosphonoacetate hydrolase [EC:3.11.1.2]Putative uncharacterized protein 2.30.30.40 73 18 76 3.35 4.37
1mhnA00 81.24 Survival motor neuron proteinSurvival motor neuron proteinHomo sapiensProtein binding 2.30.30.140 59 3 83 2.60 3.13
1i1jB00 81.12 Melanoma-derived growth regulatory proteinHomo sapiensExtracellular spaceCell proliferation 2.30.30.40 103 24 56 1.56 2.77
1udlA00 81.06 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 98 41 57 1.37 2.40
1uffA00 80.47 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 93 27 60 1.75 2.91
2k57A00 79.96 Pseudomonas syringae pv. phaseolicola 1448ALipoprotein, putative 2.30.30.100 55 9 74 2.92 3.94
1khcA01 79.71 Protein complex localizationRegulation of gene expression by genetic imprintingDNA (cytosine-5)-methyltransferase 3BChromosome, centromeric regionProtein binding 2.30.30.160 65 3 70 2.74 3.87
1ug1A00 79.70 Dynamin-binding proteinHomo sapiensProtein binding 2.30.30.40 92 24 60 1.38 2.27
2o2oA00 79.60 NucleusHomo sapiensSH3 domain-containing kinase-binding protein 1 2.30.30.40 75 29 74 2.69 3.60
2ra2B00 79.46 Salmonella enterica subsp. enterica serovar TyphimuriumPutative lipoprotein 2.30.30.100 55 9 77 3.35 4.32
1dj7B00 79.31 Ferredoxin-thioredoxin reductase, variable chainProtein bindingSynechocystis sp. PCC 6803 2.30.30.50 73 8 73 3.21 4.34
1mmdA01 78.60 ActomyosinMyosin II complexActin-myosin filament slidingProtein localizationActin filament binding 2.30.30.360 48 12 82 3.86 4.66
1vytA01 78.20 Cardiac muscle contractionRattus norvegicusDilated cardiomyopathyVoltage-gated calcium channel complexCalcium channel, voltage-dependent, beta 3 subunit 2.30.30.40 108 22 53 1.57 2.92
1jb0E00 77.76 Photosystem I subunit IVPhotosynthesisThermosynechococcus elongatus BP-1Photosystem I reaction center subunit IVMetabolic pathways 2.30.30.50 69 10 71 2.46 3.46
1m9sA05 77.74 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 78 8 70 2.80 3.97
1awjA00 77.69 Mus musculusTyrosine-protein kinase ITK/TSKProtein binding 2.30.30.40 77 22 74 2.43 3.28
2vv5A02 77.09 Escherichia coli O157:H7Small conductance mechanosensitive ion channel, MscS familySmall-conductance mechanosensitive channel 2.30.30.60 50 8 68 2.58 3.74
1ib8A02 76.97 Hypothetical proteinRibosome maturation factor rimPStreptococcus pneumoniae 2.30.30.180 67 6 76 2.69 3.53
1q3lA00 76.83 Chromatin bindingPositive regulation of transcription, DNA-dependentChromobox protein 5Drosophila melanogasterPolytene chromosome, telomeric region 2.40.50.40 52 5 63 2.33 3.65
1m9sA04 76.76 Internalin BListeria monocytogenesProtein bindingInternalin B 2.30.30.170 86 6 65 2.99 4.59
1ri9A00 76.26 FYN-binding proteinProtein phosphorylationNucleusHomo sapiensImmune response 2.30.30.40 77 12 67 3.00 4.44
2hqxA01 75.91 Staphylococcal nuclease domain-containing protein 1NucleusGolgi apparatusTranscription cofactor activityHomo sapiens 2.30.30.140 81 8 59 2.23 3.76
1u1sA00 75.84 RNA degradationPseudomonas aeruginosaHost factor-I proteinProtein hfq 2.30.30.100 66 10 62 2.48 3.99
1kq1H00 75.75 RNA degradationHost factor-I proteinSimilar to host factor-1Staphylococcus aureus subsp. aureus Mu50 2.30.30.100 66 10 63 2.57 4.04
1c8cA00 75.73 Sulfolobus solfataricusDNA-binding protein 7d 2.40.50.40 64 10 81 3.90 4.80
3be3A00 75.67 Bordetella bronchisepticaPutative uncharacterized protein 2.30.30.320 75 1 58 2.76 4.70
1biaA03 73.16 Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity 2.30.30.100 47 17 72 3.56 4.92
3by7E00 73.12 2.30.30.100 74 5 58 2.71 4.66
1d3bC00 72.00 SpliceosomeSystemic lupus erythematosusSmall nuclear ribonucleoprotein Sm D3Small nuclear ribonucleoprotein D3Spliceosomal complex 2.30.30.100 71 1 61 2.60 4.20
3fb9B00 71.55 Streptococcus pneumoniaePutative uncharacterized protein 2.30.30.100 84 6 53 2.66 4.97
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Displaying entries 1 to 74 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1jo8A00
PWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1jo8A00
PWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"