CATH Domain: 1iowA01 XML data for domain: 1iowA01

Molscript image for 1iowA01
1iowA01
PDB coordinates for domain 1iowA01

PDB 1iow, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.20 Gene3D
3.40.50.20.10
3.40.50.20.10.1
3.40.50.20.10.1.1
3.40.50.20.10.1.1.1
3.40.50.20.10.1.1.1.1

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Segment boundaries for domain 1iowA01

Chopping figure for domain 1iowA01
DomainStart PDB ResidueStop PDB Residue
1iowA01 1 84
1iowA02 85 110
1iowA02 184 306
1iowA03 111 183

Structural Neighbourhood (82 entries)

There are 82 matching structural neighberhood comparisons for CATH ID 3.40.50.20.10.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 82 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2vheA01 84.20 Campylobacter jejuniAcetyltransferase 3.40.50.20 75 13 85 2.78 3.24
1e4eA03 83.44 Vancomycin/teicoplanin A-type resistance protein vanAEnterococcus faecium 3.40.50.20 120 32 70 2.31 3.30
1a4iA02 81.69 Methenyltetrahydrofolate cyclohydrolase activityHomo sapiensC-1-tetrahydrofolate synthase, cytoplasmicProtein bindingMitochondrion 3.40.192.10 89 16 83 3.35 4.03
1vkzA01 81.17 Thermotoga maritimaPhosphoribosylamine--glycine ligase [EC:6.3.4.13]Purine metabolismPhosphoribosylamine--glycine ligaseMetabolic pathways 3.40.50.20 77 9 75 2.86 3.81
1g7sA03 80.69 Methanothermobacter thermautotrophicus str. Delta HTranslation initiation factor IF-2 unclassified subunitProbable translation initiation factor IF-2 3.40.50.10050 81 9 80 3.34 4.13
3eagA01 80.20 UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.-]Neisseria meningitidis serogroup BUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 3.40.50.720 88 15 80 2.68 3.32
3eq2B01 80.07 Pseudomonas aeruginosaProbable two-component response regulator 3.40.50.2300 103 8 70 2.62 3.70
2x5oA01 79.98 D-Glutamine and D-glutamate metabolismPeptidoglycan biosynthesisMetabolic pathwaysUDP-N-acetylmuramoylalanine--D-glutamate ligaseUDP-N-acetylmuramoylalanine-D-glutamate ligase activity 3.40.50.720 92 5 79 3.05 3.84
2iksA01 79.49 LacI family transcriptional regulator, fructose operon transcriptional repressorFructose repressorEscherichia coli K-12 3.40.50.2300 95 7 84 3.98 4.73
2ho3A01 79.27 Oxidoreductase, Gfo/Idh/MocA familyStreptococcus pneumoniae 3.40.50.720 113 10 63 2.06 3.23
2pjuA02 79.12 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 3.40.50.10660 88 14 76 3.67 4.82
1p3dA01 78.93 D-Glutamine and D-glutamate metabolismUDP-N-acetylmuramate--L-alanine ligaseUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]Haemophilus influenzaePeptidoglycan biosynthesis 3.40.50.720 87 10 79 3.14 3.96
1j6uA01 78.90 D-Glutamine and D-glutamate metabolismThermotoga maritimaUDP-N-acetylmuramate--L-alanine ligaseUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]Peptidoglycan biosynthesis 3.40.50.720 85 13 76 3.20 4.18
2q5cA02 78.69 Clostridium acetobutylicumNtrC family transcriptional regulator (PAS and AAA domains) 3.40.50.10660 89 9 75 3.61 4.80
1sr8A03 78.47 Porphyrin and chlorophyll metabolismArchaeoglobus fulgidusCobalamin biosynthesis protein CbiDPutative cobalt-precorrin-6A synthase [deacetylating]Metabolic pathways 3.40.50.10720 90 3 74 2.92 3.92
3c3mA00 78.38 Response regulator receiver proteinMethanoculleus marisnigri JR1 3.40.50.2300 104 9 63 3.01 4.74
1pjqA01 78.34 Porphyrin and chlorophyll metabolismSalmonella enterica subsp. enterica serovar TyphimuriumSiroheme synthaseUroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]Metabolic pathways 3.40.50.720 112 10 64 2.57 4.00
2b4aA00 78.18 BH3024 proteinBacillus halodurans 3.40.50.2300 116 5 64 2.63 4.07
2gfqA02 77.98 Hypothetical proteinPyrococcus horikoshiiD-tyrosyl-tRNA(Tyr) deacylase 3.40.50.10700 87 8 83 3.46 4.12
1oi7A01 77.89 Succinyl-CoA ligase [ADP-forming] subunit alphaThermus thermophilus 3.40.50.720 122 9 60 2.49 4.11
1mb3A00 77.77 Caulobacter vibrioidesTwo-component systemTwo-component system, cell cycle response regulator DivKPolar differentiation response regulatorCell cycle - Caulobacter 3.40.50.2300 115 7 63 2.64 4.16
2kyrA00 77.63 PTS system, fructose-specific IIB-like component [EC:2.7.1.69]Escherichia coli K-12Fructose-like phosphotransferase enzyme IIB component 1 3.40.50.2300 108 8 69 2.87 4.13
2r4qA00 77.62 PTS system fructose-specific EIIABC componentPTS system, fructose-specific IIB component [EC:2.7.1.69]Bacillus subtilisFructose and mannose metabolismPTS system, fructose-specific IIA component [EC:2.7.1.69] 3.40.50.2300 98 9 70 2.93 4.16
1iibA00 77.48 Phosphotransferase system (PTS)N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB componentPTS system, cellobiose-specific IIB component [EC:2.7.1.69]Escherichia coli K-12 3.40.50.270 103 8 66 2.72 4.06
2qzjA00 77.26 Two-component response regulatorClostridium difficile 630 3.40.50.2300 119 16 63 2.86 4.54
1srrC00 77.07 Sporulation initiation phosphotransferase FTwo-component system, response regulator, stage 0 sporulation protein FBacillus subtilisTwo-component system 3.40.50.2300 121 7 62 2.83 4.51
3gl9B00 77.04 Thermotoga maritimaResponse regulatorTwo-component system, unclassified family, response regulatorProtein binding 3.40.50.2300 118 10 61 2.84 4.59
1xeaA01 76.96 Vibrio choleraeOxidoreductase, Gfo/Idh/MocA familyVirulence factor 3.40.50.720 117 19 59 2.10 3.51
1ys7A01 76.92 Transcriptional regulatory protein prrAMycobacterium tuberculosis 3.40.50.2300 122 9 61 2.87 4.67
2rdmA00 76.84 Response regulator receiver proteinSinorhizobium medicae WSM419 3.40.50.2300 117 8 61 2.80 4.55
1mioB04 76.81 Nitrogenase molybdenum-iron protein beta chainClostridium pasteurianum 3.40.50.1980 98 10 66 3.02 4.55
2qr3A00 76.47 Bacteroides fragilisTwo-component system response regulator 3.40.50.2300 119 9 63 2.71 4.30
1m1nB03 76.46 Nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]Nitrogen metabolismAzotobacter vinelandiiNitrogenase molybdenum-iron protein beta chainMetabolic pathways 3.40.50.1980 106 5 61 2.76 4.50
2pjuC01 76.39 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 3.40.50.2300 100 7 69 3.22 4.67
1jflA01 76.37 Aspartate racemase [EC:5.1.1.13]228aa long hypothetical aspartate racemasePyrococcus horikoshiiAlanine, aspartate and glutamate metabolism 3.40.50.1860 119 8 61 2.63 4.29
2jbaA00 76.36 Two-component systemPhosphate regulon transcriptional regulatory protein phoBTwo-component system, OmpR family, phosphate regulon response regulator PhoBProtein bindingEscherichia coli K-12 3.40.50.2300 125 15 60 2.86 4.77
2aefA01 76.33 Methanothermobacter thermautotrophicus str. Delta HCalcium-gated potassium channel mthK 3.40.50.720 115 14 60 2.98 4.90
2qsjB00 76.32 DNA-binding response regulator, LuxR familyRuegeria pomeroyi 3.40.50.2300 122 4 55 2.26 4.05
1zgzA00 76.26 Two-component systemTorCAD operon transcriptional regulatory protein torRTwo-component system, OmpR family, torCAD operon response regulator TorRProtein bindingEscherichia coli K-12 3.40.50.2300 118 7 61 2.90 4.69
3cnbA00 75.99 DNA-binding response regulator, merR familyColwellia psychrerythraea 34H 3.40.50.2300 124 7 59 2.66 4.46
2p2sA01 75.89 Pectobacterium atrosepticumPutative oxidoreductase 3.40.50.720 130 10 55 2.42 4.37
1ydwA01 75.86 Arabidopsis thalianaUncharacterized oxidoreductase At4g09670 3.40.50.720 124 7 57 2.04 3.56
2dc1A01 75.77 Aspartate dehydrogenase [EC:1.4.1.21]Archaeoglobus fulgidusProbable L-aspartate dehydrogenaseNicotinate and nicotinamide metabolism 3.40.50.720 135 5 52 2.14 4.07
1vrvA00 75.72 Phosphotransferase system (PTS)Fructose and mannose metabolismPTS system, mannitol-specific IIC componentPTS system, mannitol-specific IIA component [EC:2.7.1.69]PTS system, mannitol-specific IIB component [EC:2.7.1.69] 3.40.50.10370 96 10 66 3.23 4.84
1i2aA02 75.67 Methanocaldococcus jannaschii50S ribosomal protein L1P 3.40.50.790 91 8 73 3.54 4.81
1yqeA02 75.64 Hypothetical proteinArchaeoglobus fulgidusD-tyrosyl-tRNA(Tyr) deacylase 3.40.50.10700 96 3 75 3.48 4.64
1jbeA00 75.63 Bacterial chemotaxisTwo-component systemEscherichia coli O157:H7Two-component system, chemotaxis family, response regulator CheYChemotaxis protein cheY 3.40.50.2300 125 14 60 2.87 4.72
3clkB01 75.43 Lactobacillus plantarumTranscription regulator 3.40.50.2300 119 13 56 2.73 4.85
1cvrA01 75.36 Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2 3.40.50.10390 117 5 66 3.15 4.72
2q5cA01 75.23 Clostridium acetobutylicumNtrC family transcriptional regulator (PAS and AAA domains) 3.40.50.2300 97 8 70 3.14 4.48
1lssA00 75.23 Trk system potassium uptake protein TrkATrk system potassium uptake protein trkA homologMethanocaldococcus jannaschii 3.40.50.720 132 9 54 2.55 4.67
1mzpA02 75.22 Sulfolobus acidocaldariusRibosomeLarge subunit ribosomal protein L150S ribosomal protein L1P 3.40.50.790 90 10 68 3.28 4.76
1bxrA05 75.20 3.40.50.20 140 23 58 2.79 4.76
1e5dA01 75.15 Desulfovibrio gigasRubredoxin-oxygen oxidoreductase 3.40.50.360 143 8 53 2.65 4.99
2qv0A00 75.12 Protein mrkEKlebsiella pneumoniae 3.40.50.2300 122 5 60 2.81 4.63
1npyA01 75.10 Shikimate 5-dehydrogenase [EC:1.1.1.25]Haemophilus influenzaePhenylalanine, tyrosine and tryptophan biosynthesisShikimate 5-dehydrogenase-like protein HI_0607Metabolic pathways 3.40.192.10 100 8 69 2.74 3.97
1efdN01 75.09 ABC transportersIron(3+)-hydroxamate-binding protein fhuDIron complex transport system substrate-binding proteinEscherichia coli K-12 3.40.50.1980 91 16 70 3.24 4.61
1jflA02 74.97 Aspartate racemase [EC:5.1.1.13]228aa long hypothetical aspartate racemasePyrococcus horikoshiiAlanine, aspartate and glutamate metabolism 3.40.50.1860 109 9 64 3.16 4.92
1z0sA01 74.94 Archaeoglobus fulgidusProbable inorganic polyphosphate/ATP-NAD kinaseNAD+ kinase [EC:2.7.1.23]Nicotinate and nicotinamide metabolismMetabolic pathways 3.40.50.10330 123 8 52 2.27 4.30
1dz3A00 74.75 Geobacillus stearothermophilusStage 0 sporulation protein A 3.40.50.2300 123 2 60 2.94 4.82
1yl5A01 74.65 Metabolic pathwaysLysine biosynthesisDihydrodipicolinate reductase [EC:1.3.1.26]Dihydrodipicolinate reductaseMycobacterium tuberculosis 3.40.50.720 140 10 52 2.31 4.37
1ep3B02 74.53 Lactococcus lactis subsp. cremoris MG1363Dihydroorotate dehydrogenase electron transfer subunitProtein bindingDihydroorotate dehydrogenase electron transfer subunit 3.40.50.80 117 8 63 2.92 4.62
2qxyA00 74.52 Thermotoga maritimaResponse regulatorTwo-component system, unclassified family, response regulator 3.40.50.2300 118 14 62 2.87 4.58
1p2fA01 74.41 Thermotoga maritimaResponse regulatorTwo-component system, OmpR family, response regulator 3.40.50.2300 117 11 58 2.66 4.58
2pfsA01 74.22 Universal stress protein (Usp)Nitrosomonas europaeaUniversal stress protein A 3.40.50.620 114 5 64 3.22 4.96
2py6A02 74.17 Methylobacillus flagellatus KTMethyltransferase FkbM 3.40.50.720 119 10 61 3.01 4.91
1lc0A01 74.17 Biliverdin reductase activityRattus norvegicusPorphyrin and chlorophyll metabolismBiliverdin reductase ABiliverdin reductase [EC:1.3.1.24] 3.40.50.720 143 9 51 2.37 4.64
1dljA02 74.17 Amino sugar and nucleotide sugar metabolismStarch and sucrose metabolismPentose and glucuronate interconversionsAscorbate and aldarate metabolismMetabolic pathways 3.40.50.1870 108 9 68 3.32 4.85
2zayA00 74.11 Response regulator receiver proteinDesulfuromonas acetoxidans DSM 684 3.40.50.2300 123 13 60 2.82 4.62
3ceaA01 74.10 Lactobacillus plantarumStreptomycin biosynthesisMyo-inositol 2-dehydrogenaseMyo-inositol 2-dehydrogenase [EC:1.1.1.18]Inositol phosphate metabolism 3.40.50.720 143 8 48 2.20 4.49
3b2nA00 74.00 Similar to two-component response regulatorStaphylococcus aureus subsp. aureus Mu50 3.40.50.2300 119 5 62 2.99 4.81
1ad2A02 73.73 RibosomeLarge subunit ribosomal protein L150S ribosomal protein L1Thermus thermophilus 3.40.50.790 93 10 75 3.51 4.66
1cdzA00 73.69 DNA repair protein XRCC1Homo sapiensProtein binding 3.40.50.10190 96 7 64 3.15 4.88
1reqB02 73.59 Propionibacterium freudenreichii subsp. shermaniiMethylmalonyl-CoA mutase small subunit 3.40.50.280 139 16 58 2.81 4.82
1qo0D01 73.59 Pseudomonas aeruginosaAliphatic amidase regulator 3.40.50.2300 127 11 55 2.51 4.55
2rjnA00 73.42 Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomainNeptuniibacter caesariensis 3.40.50.2300 135 5 56 2.69 4.78
2qaiA00 73.35 Pyrococcus furiosusOxidative phosphorylationV-type H+-transporting ATPase subunit F [EC:3.6.3.14]Metabolic pathwaysV-type ATP synthase subunit F 3.40.50.10580 89 7 69 3.15 4.52
1nvmB01 72.92 Pseudomonas sp. CF600Acetaldehyde dehydrogenase (Acylating) 3.40.50.720 158 13 46 2.30 4.98
1n2zA01 72.68 ABC transportersPeriplasmic spaceVitamin B12-binding proteinCobalamin bindingVitamin B12 transport system substrate-binding protein 3.40.50.1980 119 9 56 2.79 4.96
1q77A00 72.41 Uncharacterized protein aq_178Aquifex aeolicus 3.40.50.620 137 11 54 2.48 4.59
1b73A01 72.32 Glutamate racemaseAquifex pyrophilus 3.40.50.1860 143 16 49 2.48 4.99
1t2dA01 72.29 L-lactate dehydrogenaseCysteine and methionine metabolismGlycolysis / GluconeogenesisPyruvate metabolismPlasmodium falciparum CDC/Honduras 3.40.50.720 148 10 47 2.36 4.92
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Displaying entries 1 to 82 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1iowA01
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMG
LPYT
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1iowA01
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMG
LPYT
BLAST against CATH

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Domain History Events (4)

Update comment by auto on 16 Oct 2007 19:44

Around September/October 2007, this domain was renamed from "1iow001" to "1iowA01" as part of the work to deal with the remediation of the PDB (see http://remediation.wwpdb.org). Please see ticket:207 or wiki:Remediation on the CATH Trac system for more details.

Set cath from cathlist by auto on 05 Mar 2006 19:12

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 19:12

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:51

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"