CATH Domain: 1in4A02 XML data for domain: 1in4A02

Molscript image for 1in4A02
1in4A02
PDB coordinates for domain 1in4A02

PDB 1in4, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.10 Orthogonal Bundle
1.10.10 Arc Repressor Mutant, subunit A
1.10.10.10 "winged helix" repressor DNA binding domain Gene3D
1.10.10.10.15
1.10.10.10.15.1
1.10.10.10.15.1.1
1.10.10.10.15.1.1.1
1.10.10.10.15.1.1.1.1

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Segment boundaries for domain 1in4A02

Chopping figure for domain 1in4A02
DomainStart PDB ResidueStop PDB Residue
1in4A01 17 180
1in4A02 256 328
1in4A03 181 255

Structural Neighbourhood (119 entries)

There are 119 matching structural neighberhood comparisons for CATH ID 1.10.10.10.15.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 119 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1on2A01 88.76 Bacillus subtilisTranscriptional regulator mntR 1.10.10.10 72 16 95 2.46 2.57
2g7uA01 88.58 Rhodococcus opacusPutative regulator of catechol degradative operon 1.10.10.10 74 13 93 3.36 3.60
2dtrA01 88.46 DtxR family transcriptional regulator, Mn-dependent transcriptional regulatorDiphtheria toxin repressorCorynebacterium diphtheriae 1.10.10.10 71 14 94 2.54 2.69
1z05A01 87.44 Vibrio choleraeTranscriptional regulator, ROK family 1.10.10.10 72 12 80 2.12 2.62
2hr3D02 87.02 Probable transcriptional regulatorPseudomonas aeruginosa 1.10.10.10 61 18 79 1.70 2.14
2heoA00 86.86 Mus musculusLeft-handed Z-DNA bindingZ-DNA-binding protein 1 1.10.10.10 59 22 79 1.78 2.24
1s3jA02 86.73 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.10.10.10 62 14 75 1.35 1.79
2p8tA01 86.61 Pyrococcus horikoshiiPutative uncharacterized protein PH0730 1.10.10.10 75 12 86 3.05 3.52
2jt1A00 86.39 PefI proteinSalmonella enterica subsp. enterica serovar Typhimurium 1.10.10.10 71 16 84 2.39 2.81
1j5yA01 86.37 Thermotoga maritimaTranscriptional regulator, biotin repressor family 1.10.10.10 64 23 83 2.91 3.48
1yg2A01 86.26 Vibrio cholerae pathogenic cycleVibrio choleraePadR family transcriptional regulator, regulatory protein AphAPutative uncharacterized protein 1.10.10.10 79 6 82 3.00 3.65
1mkmB01 86.25 Thermotoga maritimaTranscriptional regulator, IclR family 1.10.10.10 76 16 92 3.86 4.19
1jhfA02 86.02 Repressor LexA [EC:3.4.21.88]TranscriptionDNA bindingLexA repressorTranscription repressor activity 1.10.10.10 69 15 84 2.13 2.51
1qbjC00 86.00 CytoplasmNucleolusHomo sapiensDouble-stranded RNA-specific adenosine deaminaseBase conversion or substitution editing 1.10.10.10 66 16 84 2.80 3.30
1lvaA03 85.97 Selenocysteine-specific elongation factorSelenocysteine-specific elongation factorMoorella thermoacetica 1.10.10.10 62 14 80 2.54 3.14
3ctaA01 85.77 Riboflavin metabolismRiboflavin kinaseRiboflavin kinase, archaea type [EC:2.7.1.161]Thermoplasma acidophilum 1.10.10.10 84 21 82 2.87 3.49
1dpuA00 85.56 DNA-dependent DNA replicationReplication protein A 32 kDa subunitNucleotide excision repairDNA replicationReplication factor A2 1.10.10.10 69 15 89 2.33 2.62
2o0yB01 85.46 Rhodococcus jostii RHA1Transcriptional regulator 1.10.10.10 64 7 82 2.53 3.08
1t6sB02 85.45 Chlorobaculum tepidumSegregation and condensation protein BSegregation and condensation protein B 1.10.10.10 77 15 83 2.61 3.14
1sfuA00 85.45 Yaba-like disease virus34L protein 1.10.10.10 70 8 87 3.31 3.78
1lddA00 85.35 Mitotic sister chromatid segregationProtein ubiquitinationCyclin catabolic processMeiosis - yeastAnaphase-promoting complex subunit 2 1.10.10.10 74 12 78 2.74 3.50
2ia2C01 85.24 Rhodococcus sp. DK17PcaR 1.10.10.10 60 11 80 2.60 3.22
3cuqB03 85.14 Homo sapiensVacuolar protein-sorting-associated protein 36ESCRT-II complex subunit VPS36Endocytosis 1.10.10.10 69 13 86 2.97 3.44
2ia2D01 85.00 Rhodococcus sp. DK17PcaR 1.10.10.10 57 12 75 2.54 3.37
1lvaA01 84.97 Selenocysteine-specific elongation factorSelenocysteine-specific elongation factorMoorella thermoacetica 1.10.10.10 59 11 75 2.46 3.27
1biaA01 84.91 Biotin metabolismDNA bindingBirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]Bifunctional protein birABiotin-[acetyl-CoA-carboxylase] ligase activity 1.10.10.10 64 14 83 2.69 3.22
2qvoA00 84.88 Archaeoglobus fulgidusUncharacterized protein AF_1382 1.10.10.10 87 16 82 3.10 3.75
2qm3A01 84.78 Pyrococcus furiosusPutative uncharacterized protein 1.10.10.10 81 9 80 2.93 3.65
3b73A00 84.77 PhiH1 repressor-likeHaloarcula marismortui 1.10.10.10 86 17 80 2.83 3.53
1w1wE00 84.58 Nuclear mitotic cohesin complexProtein acetylationChromatin bindingCohesin complex subunit SCC1Establishment of mitotic sister chromatid cohesion 1.10.10.580 70 7 86 2.79 3.23
1ldjA06 84.52 Cullin-1Cell cycle arrestInduction of apoptosis by intracellular signalsUbiquitin mediated proteolysisWnt signaling pathway 1.10.10.10 68 14 75 2.40 3.19
1lvaA04 84.50 Selenocysteine-specific elongation factorSelenocysteine-specific elongation factorMoorella thermoacetica 1.10.10.10 60 23 82 2.06 2.51
1p6rA00 84.32 Bacillus licheniformisPenicillinase repressor 1.10.10.10 82 13 81 3.80 4.65
1stzA01 84.28 Thermotoga maritimaHeat-inducible transcription repressor hrcAHeat-inducible transcriptional repressor 1.10.10.10 85 23 84 2.98 3.52
1ft9A02 84.17 Rhodospirillum rubrumCooA protein 1.10.10.10 79 12 83 2.68 3.21
1hstA00 84.03 Histone H1/5Gallus gallusHistone H5 1.10.10.10 74 12 82 3.53 4.28
3jthB00 83.95 Transcription activator HlyUVibrio vulnificus 1.10.10.10 88 12 73 2.45 3.32
2pn6A01 83.89 150aa long hypothetical transcriptional regulatorSulfolobus tokodaii 1.10.10.10 52 25 71 2.94 4.13
1hw5A02 83.85 TranscriptionTranscription activator activityTranscription repressor activityCRP/FNR family transcriptional regulator, cyclic AMP receptor proteinCatabolite gene activator 1.10.10.10 68 11 78 2.47 3.16
1lvaA02 83.81 Selenocysteine-specific elongation factorSelenocysteine-specific elongation factorMoorella thermoacetica 1.10.10.10 69 7 83 2.91 3.48
1u5tB02 83.76 Protein targeting to vacuoleVacuolar protein-sorting-associated protein 36Protein retention in Golgi apparatusUbiquitin bindingEndocytosis 1.10.10.10 69 13 79 2.15 2.71
1bjaA00 83.60 Transcription regulatory protein motAEnterobacteria phage T4 1.10.10.10 95 16 72 2.53 3.48
3bz6A01 83.48 Hypothetical proteinPseudomonas syringae pv. tomatoUPF0502 protein PSPTO_2686 1.10.10.10 88 16 76 2.50 3.28
1tbxB00 83.48 Sulfolobus virus 1Protein F-93 1.10.10.10 89 13 77 3.61 4.66
2jtvA00 83.45 Rhodopseudomonas palustrisPutative uncharacterized protein 1.10.10.10 65 15 82 2.86 3.48
2ia0A01 83.31 Pyrococcus furiosusUncharacterized HTH-type transcriptional regulator PF0864 1.10.10.10 54 22 73 3.61 4.88
1q1hA00 83.31 Sulfolobus solfataricusTranscription initiation factor TFIIE alpha subunitTranscription factor EBasal transcription factors 1.10.10.10 85 10 75 2.32 3.08
2dbbB01 83.30 Pyrococcus horikoshiiUncharacterized HTH-type transcriptional regulator PH0061 1.10.10.10 55 18 72 3.16 4.35
2o0yC01 83.12 Rhodococcus jostii RHA1Transcriptional regulator 1.10.10.10 73 6 79 2.67 3.36
1r1uB00 83.08 CzrA proteinStaphylococcus aureus 1.10.10.10 93 6 73 3.42 4.68
3cloA02 83.06 Bacteroides thetaiotaomicronTranscriptional regulator 1.10.10.10 63 19 82 3.50 4.26
2r3sB01 83.02 1.10.10.10 76 13 72 1.70 2.35
2hoeA01 82.96 Thermotoga maritimaTranscriptional regulator, XylR-related 1.10.10.10 57 24 69 1.48 2.12
1xb4B02 82.95 Protein targeting to vacuoleESCRT-II complex subunit VPS25Saccharomyces cerevisiaeESCRT II complexVacuolar protein-sorting-associated protein 25 1.10.10.10 75 10 80 2.89 3.61
1r1tA00 82.91 Transcriptional repressor smtBSynechococcus elongatus PCC 7942 1.10.10.10 98 10 68 2.31 3.38
3cuqA02 82.89 ESCRT-II complex subunit VPS22Transcription factor bindingRegulation of transcription from RNA polymerase II promoterHomo sapiensVacuolar-sorting protein SNF8 1.10.10.10 81 16 75 2.97 3.94
1yioA02 82.86 Response regulatory proteinPseudomonas fluorescens 1.10.10.10 59 16 80 3.14 3.89
2w25A01 82.68 Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory proteinLeucine-responsive regulatory proteinMycobacterium tuberculosis 1.10.10.10 52 19 71 3.43 4.82
1cf7B00 82.67 Protein domain specific bindingTranscription factor Dp-2Transcription cofactor activityHomo sapiens 1.10.10.10 82 12 73 2.91 3.98
1ub9A00 82.66 Pyrococcus horikoshiiPutative uncharacterized protein PH1061 1.10.10.10 100 9 69 2.86 4.14
2pg4A00 82.63 Aeropyrum pernixPutative uncharacterized protein 1.10.10.10 90 20 80 3.12 3.90
1ulyA01 82.62 Pyrococcus horikoshiiPutative uncharacterized protein PH1932 1.10.10.10 86 19 74 3.05 4.10
1bbyA00 82.49 Basal transcription factorsGeneral transcription factor IIF subunit 2General RNA polymerase II transcription factor activityHomo sapiensTranscription initiation factor TFIIF beta subunit 1.10.10.10 69 7 86 3.38 3.92
2p5vA01 82.41 Neisseria meningitidis serogroup BTranscriptional regulator, AsnC familyLrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein 1.10.10.10 52 21 71 3.40 4.77
2hgcA00 82.34 Bacillus subtilisUncharacterized protein yjcQ 1.10.10.10 78 21 80 3.27 4.05
1ku9A01 82.16 DNA-binding protein MJ1563Methanocaldococcus jannaschii 1.10.10.10 83 10 68 1.78 2.59
1cf7A00 82.02 Protein domain specific bindingTranscription factor bindingE2F transcription factor 4/5Transcription factor E2F4TGF-beta signaling pathway 1.10.10.10 67 14 83 3.07 3.67
3edpA01 81.99 Listeria innocuaLin2111 protein 1.10.10.10 75 16 90 4.13 4.56
2hztC00 81.84 Bacillus subtilisUncharacterized HTH-type transcriptional regulator ytcD 1.10.10.10 88 12 75 3.14 4.19
1a04A02 81.70 Two-component systemTwo-component system, NarL family, nitrate/nitrite response regulator NarLProtein bindingEscherichia coli K-12Nitrate/nitrite response regulator protein narL 1.10.10.10 80 17 75 2.78 3.71
1d8jA00 81.69 Basal transcription factorsTranscription initiation factor IIE subunit betaTranscription initiation factor TFIIE beta subunitHomo sapiensProtein binding 1.10.10.10 81 6 82 3.85 4.65
2fswA00 81.58 Porphyromonas gingivalisPutative uncharacterized protein 1.10.10.10 99 12 68 2.88 4.19
2f2eA01 81.56 Pseudomonas aeruginosaPutative uncharacterized protein 1.10.10.10 89 17 74 3.37 4.54
2dt5B01 81.40 Thermus thermophilus HB8Redox-sensing transcriptional repressor rexAT-rich DNA-binding protein 1.10.10.10 73 9 84 3.78 4.45
3i53B01 81.38 O-methyltransferaseStreptomyces carzinostaticus subsp. neocarzinostaticus 1.10.10.10 91 15 73 2.85 3.87
3bwgB01 81.27 GntR family transcriptional regulator, transcriptional regulator of bglABacillus subtilisUncharacterized HTH-type transcriptional regulator yydK 1.10.10.10 68 17 86 3.67 4.25
1o57A01 81.26 Pur operon repressorBacillus subtilisPurine operon repressor 1.10.10.10 72 11 80 3.97 4.91
2vkvA01 81.21 Escherichia coliTetracycline repressor protein class DTetracycline repressor protein class B from transposon Tn10 1.10.10.60 61 16 76 3.30 4.30
2krfA00 81.14 Transcriptional regulatory protein comABacillus subtilisTwo-component systemTwo-component system, NarL family, competent response regulator ComA 1.10.10.10 69 8 84 4.10 4.83
2hs5A01 80.96 Rhodococcus jostii RHA1Probable transcriptional regulator, GntR family protein 1.10.10.10 67 17 83 3.55 4.25
2fnaA03 80.41 Sulfolobus solfataricusPutative uncharacterized protein 1.10.10.10 72 11 90 3.65 4.04
2esnA01 80.38 Probable transcriptional regulatorPseudomonas aeruginosa 1.10.10.10 89 15 75 3.25 4.32
1b4aA01 80.37 Geobacillus stearothermophilusArginine repressor 1.10.10.10 59 16 67 2.64 3.93
3df8A00 80.20 Thermoplasma volcanium GSS1Putative uncharacterized protein TVG1336486 1.10.10.10 94 15 69 3.44 4.97
1sauA02 79.98 Archaeoglobus fulgidusSulfite reductase, desulfoviridin-type subunit gamma (DsvC) 1.10.10.370 70 8 78 3.53 4.52
1fnnB03 79.92 Pyrobaculum aerophilumCell division control protein 6 (Cdc6), putativeArchaeal cell division control protein 6 1.10.10.10 103 13 68 3.41 4.95
3bddD00 79.31 Streptococcus suis 89/1591Transcriptional regulator, MarR family 1.10.10.10 128 20 50 1.71 3.37
2a6hF02 79.31 Thermus thermophilus HB8RNA polymerase sigma factorRNA polymerase primary sigma factor 1.10.10.10 54 14 63 2.36 3.75
1t56A01 79.10 TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHRMycobacterium tuberculosis 1.10.10.60 46 21 58 2.84 4.82
3h92A00 78.96 Methanocaldococcus jannaschiiUncharacterized ATP-binding protein MJECL15 1.10.10.10 85 5 68 2.44 3.58
3ccyA01 78.72 Bordetella parapertussisPutative TetR-family transcriptional regulator 1.10.10.60 44 13 57 2.47 4.29
1kgsA02 78.51 Thermotoga maritimaResponse regulatorTwo-component system, OmpR family, response regulator 1.10.10.10 97 15 62 2.82 4.48
1p4wA00 78.48 Two-component systemErwinia amylovoraRcsB proteinTwo-component system, NarL family, captular synthesis response regulator RcsB 1.10.10.10 87 9 72 2.92 4.03
2a61B00 78.36 Thermotoga maritimaTranscriptional regulator, MarR family 1.10.10.10 136 23 50 2.45 4.90
2ibdA01 78.33 Rhodococcus jostii RHA1Possible transcriptional regulator 1.10.10.60 45 11 57 2.75 4.78
1hsjA03 78.28 Staphylococcus aureus subsp. aureus NCTC 8325HTH-type transcriptional regulator sarR 1.10.10.10 82 10 63 1.96 3.09
1w0uA00 78.24 Protein homodimerization activityTelomeric repeat-binding factor 2Protein C-terminus bindingTelomeric loop formationProtection from non-homologous end joining at telomere 1.10.10.60 55 7 65 3.24 4.93
2hyjA01 78.22 Streptomyces coelicolorPutative tetR-family transcriptional regulator 1.10.10.60 46 15 57 2.41 4.19
1fipA00 78.22 Escherichia coli O157:H7DNA-binding protein fisFis family transcriptional regulator, factor for inversion stimulation protein 1.10.10.60 73 6 58 2.47 4.19
1etxA00 78.13 DNA-binding protein fisFis family transcriptional regulator, factor for inversion stimulation proteinProtein bindingEscherichia coli K-12 1.10.10.60 74 5 59 2.37 3.99
1jgsA00 78.12 Multiple antibiotic resistance protein marRMarR family transcriptional regulatorEscherichia coli K-12 1.10.10.10 138 16 50 2.47 4.94
2rdpA00 78.11 Geobacillus stearothermophilusPutative transcriptional regulator MarR 1.10.10.10 135 12 49 2.48 5.00
1fp1D01 78.07 Medicago sativaIsoliquiritigenin 2'-O-methyltransferase 1.10.10.10 105 13 63 2.55 4.00
1s6lA01 78.03 Alkylmercury lyaseEscherichia coli 1.10.10.10 52 17 69 2.24 3.21
2fbhA00 77.93 Probable transcriptional regulatorPseudomonas aeruginosaMarR family transcriptional regulator, transcriptional regulator for hemolysin 1.10.10.10 137 23 51 2.49 4.87
2nyxB01 77.89 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEINMycobacterium tuberculosis 1.10.10.10 140 17 48 2.39 4.92
1p2fA02 77.85 Thermotoga maritimaResponse regulatorTwo-component system, OmpR family, response regulator 1.10.10.10 94 13 64 2.60 4.01
1je8E00 77.84 Two-component systemEscherichia coli O157:H7Two-component system, NarL family, nitrate/nitrite response regulator NarLNitrate/nitrite response regulator protein narL 1.10.10.10 64 12 78 3.65 4.67
2raeA01 77.69 Rhodococcus jostii RHA1Transcriptional regulator, AcrR family protein 1.10.10.60 43 20 54 1.88 3.43
2fbiA00 77.31 Probable transcriptional regulatorPseudomonas aeruginosa 1.10.10.10 136 15 50 2.52 4.97
1opcA00 77.15 Two-component systemTwo-component system, OmpR family, phosphate regulon response regulator OmpRTranscriptional regulatory protein ompRProtein bindingEscherichia coli K-12 1.10.10.10 99 10 62 2.89 4.61
1ojlA03 77.12 Two-component systemTwo-component system, NtrC family, response regulator HydGTranscriptional regulatory protein zraRSalmonella enterica subsp. enterica serovar Typhimurium 1.10.10.60 47 17 54 2.53 4.62
3broD00 77.05 Oenococcus oeni PSU-1Transcriptional regulator 1.10.10.10 128 15 53 2.54 4.71
1bl0A01 76.82 Multiple antibiotic resistance protein marAAraC family transcriptional regulator, multiple antibiotic resistance protein MarAEscherichia coli K-12 1.10.10.60 56 10 76 3.76 4.90
3c18A03 76.50 Exiguobacterium sibiricum 255-15Putative uncharacterized protein 1.10.10.10 54 11 58 2.28 3.87
1oyiA00 76.23 Vaccinia virusDouble-stranded RNA-binding protein 1.10.10.10 62 8 75 2.96 3.93
1duxC00 75.63 ETS domain-containing protein Elk-1Positive regulation of transcription from RNA polymerase II promoterPrion diseasesInsulin signaling pathwayEndometrial cancer 1.10.10.10 86 12 73 3.45 4.71
3cuqD00 75.50 ESCRT-II complex subunit VPS25Homo sapiensVacuolar protein-sorting-associated protein 25Endocytosis 1.10.10.570 97 8 62 2.94 4.68
1ldkB03 75.22 Cullin-1Cell cycle arrestInduction of apoptosis by intracellular signalsUbiquitin mediated proteolysisWnt signaling pathway 1.10.10.10 83 6 66 3.28 4.95
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Displaying entries 1 to 119 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1in4A02
GLDEFDRKILKTIIEIYRGGPVGLNALAASLGVEADTLSEVYEPYLLQAGFLARTPRGRIVTEKAYKHLKYEV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1in4A02
GLDEFDRKILKTIIEIYRGGPVGLNALAASLGVEADTLSEVYEPYLLQAGFLARTPRGRIVTEKAYKHLKYEV
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:02

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:02

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:51

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"