CATH Domain: 1iarB01 XML data for domain: 1iarB01

Molscript image for 1iarB01
1iarB01
PDB coordinates for domain 1iarB01

PDB 1iar, Chain B, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.169
2.60.40.10.169.1
2.60.40.10.169.1.1
2.60.40.10.169.1.1.1
2.60.40.10.169.1.1.1.1

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Segment boundaries for domain 1iarB01

Chopping figure for domain 1iarB01
DomainStart PDB ResidueStop PDB Residue
1iarB01 1 96
1iarB02 97 197

Structural Neighbourhood (68 entries)

There are 68 matching structural neighberhood comparisons for CATH ID 2.60.40.10.169.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 68 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2gysA03 82.79 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaApoptosis 2.60.40.10 86 16 84 3.20 3.79
2qfpA01 82.77 Fe(3+)-Zn(2+) purple acid phosphatasePhaseolus vulgaris 2.60.40.380 97 7 90 2.90 3.20
2gysA01 82.40 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaCytokine-cytokine receptor interaction 2.60.40.10 95 14 85 3.80 4.45
1tdqA02 82.32 Nervous system developmentRattus norvegicusTenascinFocal adhesionProteinaceous extracellular matrix 2.60.40.10 90 12 88 2.51 2.83
1owwA00 81.62 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 93 9 90 3.13 3.45
1qr4A01 81.35 TenascinGallus gallus 2.60.40.10 87 10 86 2.96 3.42
1cwvA02 81.21 InvasinYersinia pseudotuberculosis 2.60.40.920 97 6 82 2.99 3.63
1g0dA04 81.07 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 97 9 90 3.96 4.37
1cd9D01 81.05 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 107 12 86 3.40 3.91
1qg3A01 81.03 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 91 15 86 3.03 3.50
1j8kA00 80.95 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 94 12 90 3.21 3.54
1axiB01 80.93 Jak-STAT signaling pathwayMulticellular organismal metabolic processCell surfaceGrowth hormone receptor complexInsulin-like growth factor receptor signaling pathway 2.60.40.10 86 18 86 3.39 3.92
2jllA04 80.73 Prion diseasesNeural cell adhesion moleculePlasma membraneNeuron cell-cell adhesionNeural cell adhesion molecule 2 2.60.40.10 91 9 85 3.28 3.84
1fnhA03 80.54 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 12 84 2.82 3.34
2cumA00 80.51 Collagen metabolic processElastic fiber assemblyIntracellularHomo sapiensTenascin-X 2.60.40.10 105 9 81 3.20 3.91
1jz7A02 80.44 Galactose metabolismSphingolipid metabolismOther glycan degradationMetabolic pathwaysLactose catabolic process 2.60.40.320 114 5 78 2.74 3.51
1p53A01 80.40 Leukocyte migrationAdhesion to symbiontHeterophilic cell-cell adhesionRegulation of leukocyte mediated cytotoxicityT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2.60.40.10 98 11 89 3.71 4.13
1ix2A00 80.25 Escherichia coliCopper resistance protein C 2.60.40.1220 97 6 90 3.75 4.13
2dtgE05 80.18 Insulin receptorInsulin receptor complexPhosphoinositide 3-kinase bindingPositive regulation of nitric oxide biosynthetic processPositive regulation of respiratory burst 2.60.40.10 98 14 85 4.06 4.74
2e7hA01 79.95 Cell surfaceOrgan morphogenesisIntegral to plasma membraneEph receptor B4 [EC:2.7.10.1]Homo sapiens 2.60.40.10 89 7 84 3.47 4.11
1dr9A02 79.94 Type I diabetes mellitusIntestinal immune network for IgA productionAutoimmune thyroid diseaseAllograft rejectionT-lymphocyte activation antigen CD80 2.60.40.10 95 8 86 3.86 4.46
1koaA03 79.85 Caenorhabditis elegansProtein ZK617.1b, partially confirmed by transcript evidenceLocomotionReproduction 2.60.40.10 96 5 88 4.33 4.89
1cvrA03 79.80 Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2 2.60.40.10 83 7 82 2.97 3.61
1im3D00 79.76 Unique short US2 glycoproteinHuman herpesvirus 5 strain AD169 2.60.40.1200 95 12 88 3.85 4.35
1ej6A05 79.50 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 9 82 3.01 3.66
1cd9B02 79.18 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 98 11 85 3.59 4.19
2gysA02 79.03 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 102 7 86 3.81 4.42
1fnhA02 78.93 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 6 85 3.99 4.67
2nziA03 78.66 Structural constituent of muscleCalcium ion bindingSarcomere organizationTelethonin bindingActin filament binding 2.60.40.10 94 5 89 4.45 4.97
1o75A04 78.53 Treponema pallidum47 kDa membrane antigen 2.60.40.1270 82 4 81 3.28 4.04
2uzyB03 78.44 Hepatocyte growth factor receptor activityBasal plasma membranePathways in cancerEpithelial cell signaling in Helicobacter pylori infectionProto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] 2.60.40.10 87 8 80 3.36 4.19
1jz7A04 78.42 Galactose metabolismSphingolipid metabolismOther glycan degradationMetabolic pathwaysLactose catabolic process 2.60.40.320 106 7 83 4.03 4.80
1fnhA01 78.41 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 10 87 3.81 4.35
1iarB02 78.39 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneReceptor signaling protein activityHematopoietic cell lineage 2.60.40.10 92 3 78 3.43 4.39
1cwvA03 78.38 InvasinYersinia pseudotuberculosis 2.60.40.920 102 6 81 3.66 4.50
3hn3A02 78.25 Beta-glucuronidaseGlycosaminoglycan degradationGlycosaminoglycan catabolic processMetabolic pathwaysStarch and sucrose metabolism 2.60.40.320 103 9 80 3.66 4.54
1n6uA01 78.19 JAK-STAT cascadeIntegral to plasma membraneType I interferon receptor activityHomo sapiensResponse to virus 2.60.40.10 106 11 79 3.50 4.42
2fnbA00 78.11 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 95 4 85 3.93 4.60
3cmgA04 78.10 Putative beta-galactosidaseBacteroides fragilis NCTC 9343 2.60.40.1560 87 13 83 4.00 4.80
1k85A00 77.96 Bacillus circulansChitinase A1 2.60.40.10 88 10 81 3.39 4.17
1p7hL02 77.77 Nuclear factor of activated T-cells, cytoplasmic 2Sequence-specific DNA binding transcription factor activityTranscription activator activityNucleusHomo sapiens 2.60.40.10 107 6 84 3.21 3.82
1cidA02 77.74 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 71 16 72 2.81 3.85
1ujtA00 77.63 LuteolysisPositive regulation of axonogenesisCell surfaceIdentical protein bindingHomophilic cell adhesion 2.60.40.10 120 9 75 3.58 4.77
1imhC02 77.56 Nuclear factor of activated T-cells 5Transcription from RNA polymerase II promoterSequence-specific DNA binding transcription factor activityNucleusExcretion 2.60.40.10 106 5 86 4.08 4.70
2ec8A05 77.55 Pathways in cancerHematopoietic cell lineageProto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]Extracellular spaceAcute myeloid leukemia 2.60.40.10 81 7 79 3.95 4.99
1eh9A03 77.50 Sulfolobus solfataricusMalto-oligosyltrehalose trehalohydrolase 2.60.40.10 87 5 76 2.99 3.93
1dceA02 77.34 Rattus norvegicusRab geranylgeranyltransferase activityProtein geranylgeranyltransferase type II [EC:2.5.1.60]Geranylgeranyl transferase type-2 subunit alpha 2.60.40.1130 103 7 80 3.25 4.03
2c4fT00 77.23 Positive regulation of endothelial cell proliferationTissue factorPositive regulation of platelet-derived growth factor receptor signaling pathwayPositive regulation of angiogenesisProtease binding 2.60.40.10 75 9 76 3.60 4.73
1je6A02 77.10 Response to heatMHC class I polypeptide-related sequence BGamma-delta T cell activationImmune response-activating cell surface receptor signaling pathwayResponse to retinoic acid 2.60.40.10 89 3 76 3.11 4.09
1f00I01 77.05 Pathogenic Escherichia coli infectionIntiminIntiminProtein bindingEscherichia coli O127:H6 str. E2348/69 2.60.40.920 95 4 89 4.10 4.58
2gysB04 76.94 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 99 8 79 3.42 4.29
3bgaA04 76.85 Galactose metabolismBacteroides thetaiotaomicronBeta-galactosidaseSphingolipid metabolismBeta-galactosidase [EC:3.2.1.23] 2.60.40.320 105 9 84 3.76 4.44
1pd6A00 76.62 Myosin-binding protein C, cardiac-typeHomo sapiensVentricular cardiac muscle tissue morphogenesisStriated muscle myosin thick filamentStructural constituent of muscle 2.60.40.10 94 8 86 3.73 4.31
1n26A02 76.53 Positive regulation of chemokine productionPositive regulation of smooth muscle cell proliferationJak-STAT signaling pathwayAcute-phase responsePositive regulation of osteoblast differentiation 2.60.40.10 78 6 78 3.77 4.83
1ow0A01 76.51 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 100 5 83 3.54 4.27
2uzyB04 76.13 Basal plasma membraneHepatocyte growth factor receptor activityEpithelial cell signaling in Helicobacter pylori infectionPathways in cancerProto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] 2.60.40.10 79 8 80 3.03 3.78
1h8lA02 75.90 Zinc ion bindingLophonetta specularoidesCarboxypeptidase D 2.60.40.1120 79 5 67 3.00 4.43
1l0qA02 75.89 Methanosarcina mazeiORF492 2.60.40.670 90 5 76 3.79 4.98
1jmxA03 75.81 Quinohemoprotein amine dehydrogenase 60 kDa subunitPseudomonas putida 2.60.40.10 79 5 81 3.94 4.85
1y6kR01 75.59 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 102 8 86 3.87 4.49
2gy5A02 75.57 Cell surfaceMicrovillusTransmembrane receptor protein tyrosine kinase signaling pathwayProtein bindingSignal transduction 2.60.40.10 90 6 84 4.17 4.94
3fruA02 75.55 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 11 81 4.03 4.96
2dtgE04 75.03 Insulin receptorInsulin receptor complexPhosphoinositide 3-kinase bindingPositive regulation of respiratory burstPositive regulation of nitric oxide biosynthetic process 2.60.40.10 123 5 73 3.64 4.97
1ifrA00 75.03 Perinuclear region of cytoplasmMuscle organ developmentLamin-A/CStructural molecule activityHomo sapiens 2.60.40.1260 113 5 73 3.56 4.85
1p5uA02 74.63 Yersinia pestisChaperone protein caf1MProtein binding 2.60.40.1070 84 5 77 3.51 4.55
1ulvA03 74.54 GlucodextranaseArthrobacter globiformis 2.60.40.1560 86 6 80 3.70 4.61
3k6iA00 74.48 Gallus gallusCadherin-13 2.60.40.60 99 3 80 3.38 4.18
2uzxB02 73.21 Hepatocyte growth factor receptor activityBasal plasma membraneEpithelial cell signaling in Helicobacter pylori infectionPathways in cancerProto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] 2.60.40.10 121 7 67 3.34 4.93
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Displaying entries 1 to 68 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1iarB01
FKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWA
GQQLLWKGSFKPSEHV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1iarB01
FKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWA
GQQLLWKGSFKPSEHV
BLAST against CATH

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Domain History Events (4)

Classification merge by cuff on 16 Jun 2009 15:28

COMMENT: merge 2.60.40.30 -> 2.60.40.10 FINAL: superfamily merge

Set cath from cathlist by auto on 05 Mar 2006 18:40

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:40

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:50

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"