CATH Domain: 1i24A01 XML data for domain: 1i24A01

Molscript image for 1i24A01
1i24A01
PDB coordinates for domain 1i24A01

PDB 1i24, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.19
3.40.50.720.19.1
3.40.50.720.19.1.1
3.40.50.720.19.1.1.1
3.40.50.720.19.1.1.1.1

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Segment boundaries for domain 1i24A01

Chopping figure for domain 1i24A01
DomainStart PDB ResidueStop PDB Residue
1i24A01 1 209
1i24A01 268 294
1i24A02 210 267
1i24A02 295 378

Structural Neighbourhood (38 entries)

There are 38 matching structural neighberhood comparisons for CATH ID 3.40.50.720.19.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 38 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1n7hA02 85.83 Amino sugar and nucleotide sugar metabolismGDPmannose 4,6-dehydratase [EC:4.2.1.47]Fructose and mannose metabolismCytosolMetabolic pathways 3.40.50.720 231 16 82 2.43 2.93
1wvgA01 84.16 3.40.50.720 193 20 73 2.23 3.03
1eq2A01 83.23 Metabolic pathwaysLipopolysaccharide biosynthesisMembraneProtein bindingADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] 3.40.50.720 202 15 79 2.71 3.41
2hrzA01 83.22 Agrobacterium tumefaciens str. C58Nucleoside-diphosphate-sugar epimerase 3.40.50.720 224 12 80 3.19 3.95
1vl0B01 82.76 DTDP-4-dehydrorhamnose reductase, rfbD orthologDTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesis 3.40.50.720 200 15 71 1.93 2.68
2ew8B00 82.17 Ethylbenzene degradation(S)-1-Phenylethanol dehydrogenaseAromatoleum aromaticum EbN1 3.40.50.720 228 10 81 3.63 4.44
1hxhA00 82.07 3-beta-hydroxysteroid dehydrogenaseComamonas testosteroni 3.40.50.720 253 8 75 3.41 4.52
2o23A00 81.86 3-hydroxyacyl-CoA dehydrogenase type-2Lipid metabolic process7-alpha-hydroxysteroid dehydrogenase activityPlasma membraneHomo sapiens 3.40.50.720 241 11 75 2.65 3.53
1zemA00 81.78 Gluconobacter oxydansXylitol dehydrogenase 3.40.50.720 260 14 73 2.75 3.74
1spxA00 81.76 Caenorhabditis elegansProtein D1054.8, confirmed by transcript evidenceDetermination of adult lifespan 3.40.50.720 237 10 79 3.15 3.97
1cydA00 81.40 Carbonyl reductase (NADPH) activityArachidonic acid metabolismProtein tetramerizationCarbonyl reductase [NADPH] 2Metabolic pathways 3.40.50.720 242 12 77 3.58 4.61
2z1nA00 81.39 Aeropyrum pernix3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Putative dehydrogenaseFatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 237 11 82 3.51 4.27
3grpD00 81.34 3-oxoacyl-(Acyl carrierprotein) reductaseBartonella henselae3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 209 7 74 2.83 3.82
1iy8A00 81.31 Leifsonia aquaticaLevodione reductase 3.40.50.720 258 11 74 3.04 4.06
1zk4A00 81.27 Lactobacillus brevisR-specific alcohol dehydrogenase 3.40.50.720 244 9 78 3.69 4.71
2ag5C00 81.26 NAD or NADH bindingMetabolic pathwaysButanoate metabolismCytoplasm3-hydroxybutyrate dehydrogenase type 2 3.40.50.720 244 8 77 3.55 4.56
1xg5B00 81.14 Dehydrogenase/reductase SDR family member 11Homo sapiens 3.40.50.720 241 11 78 3.19 4.07
1gz6B01 80.86 PeroxisomeRattus norvegicusPrimary bile acid biosynthesis3(or 17)beta-hydroxysteroid dehydrogenase activityPeroxisomal multifunctional enzyme type 2 3.40.50.720 219 11 79 3.46 4.37
1sbyA00 80.79 Scaptodrosophila lebanonensisAlcohol dehydrogenase 3.40.50.720 252 13 72 2.65 3.65
2qq5A00 80.77 NucleusGolgi apparatusEndoplasmic reticulumHomo sapiensDehydrogenase/reductase SDR family member 1 3.40.50.720 238 11 80 3.00 3.72
2a4kB01 80.74 3.40.50.720 196 12 69 2.93 4.22
1geeA00 80.70 Bacillus megateriumGlucose 1-dehydrogenase 3.40.50.720 261 8 74 3.65 4.89
1fmcA00 80.69 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]7-alpha-hydroxysteroid dehydrogenaseEscherichia coli K-12Cytosol 3.40.50.720 255 10 75 3.55 4.69
1kbzA01 80.68 Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesisDTDP-4-dehydrorhamnose reductaseSalmonella enterica subsp. enterica serovar Typhimurium 3.40.50.720 213 12 76 2.76 3.62
2zatA00 80.47 PeroxisomeDehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]Sus scrofaDehydrogenase/reductase SDR family member 4Retinol metabolism 3.40.50.720 251 11 76 3.12 4.08
2rhcA00 80.37 Putative ketoacyl reductaseBiosynthesis of type II polyketide backboneStreptomyces coelicolorKetoacyl reductase [EC:1.3.1.-] 3.40.50.720 257 11 74 3.08 4.12
3iccA00 80.35 Bacillus anthracisOxidoreductase, short-chain dehydrogenase/reductase family 3.40.50.720 248 8 77 3.69 4.77
2p91C00 80.33 Enoyl-[acyl-carrier-protein] reductase [NADH]Aquifex aeolicus 3.40.50.720 228 10 81 3.59 4.42
1ydeN00 80.28 17-beta-hydroxysteroid dehydrogenase 14Testosterone 17-beta-dehydrogenase (NADP+) activityEstradiol 17-beta-dehydrogenase activitySteroid catabolic processHomo sapiens 3.40.50.720 240 8 79 3.81 4.81
1xu9C00 80.22 Aldosterone-regulated sodium reabsorptionCorticosteroid 11-beta-dehydrogenase isozyme 1Homo sapiensSteroid hormone biosynthesis11beta-hydroxysteroid dehydrogenase [EC:1.1.1.146] 3.40.50.720 258 11 73 3.47 4.71
1bdbA00 79.95 Biphenyl degradationCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase [EC:1.3.1.56]Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenaseBurkholderia xenovorans LB400Metabolic pathways 3.40.50.720 267 9 71 3.17 4.43
3gemD00 79.85 Pseudomonas syringae pv. phaseolicola 1448A[EC:1.-.-.-]Oxidoreductase, short chain dehydrogenase/reductase family 3.40.50.720 209 8 78 3.63 4.64
2ztuB00 79.73 Pseudomonas fragiD(-)-3-hydroxybutyrate dehydrogenase 3.40.50.720 207 8 73 3.55 4.85
3d7lA00 79.62 Listeria innocuaLin1944 protein 3.40.50.720 196 10 72 3.46 4.78
1xq1A00 79.36 Arabidopsis thalianaTropinone reductase homolog At1g07440Response to cadmium ion 3.40.50.720 218 10 76 2.98 3.91
3e8xA00 79.00 BH1520 proteinBacillus halodurans 3.40.50.720 204 10 70 2.97 4.20
1oaaA00 78.54 DeathRegulation of multicellular organism growthProtein homodimerization activitySepiapterin reductasePteridine metabolic process 3.40.50.720 259 7 74 3.58 4.80
2h7iA00 77.77 Enoyl-[acyl-carrier-protein] reductase [NADH]Enoyl ACP reductase [EC:1.3.1.9]Mycobacterium tuberculosis 3.40.50.720 268 11 71 3.54 4.97
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Displaying entries 1 to 38 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1i24A01
GSRVMVIGGDGYCGWATALHLSKKNYEVCIVDNLVRRLFDHQLGLESLTPIASIHDRISRWKALTGKSIELYVGDICDFE
FLAESFKSFEPDSVVHFGEQRSAPYSMIDRSRAVYTQHNNVIGTLNVLFAIKEFGEECHLVKLGTMGEYGTPNIDIEEGY
ITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWGIRATDLNQIRDTVQCVEIAIANPAKAGEFRVFNQF
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1i24A01
MRGSHHHHHHGSRVMVIGGDGYCGWATALHLSKKNYEVCIVDNLVRRLFDHQLGLESLTPIASIHDRISRWKALTGKSIE
LYVGDICDFEFLAESFKSFEPDSVVHFGEQRSAPYSMIDRSRAVYTQHNNVIGTLNVLFAIKEFGEECHLVKLGTMGEYG
TPNIDIEEGYITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWGIRATDLNQIRDTVQCVEIAIANPAKAGEF
RVFNQF
BLAST against CATH

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Domain History Events (2)

Domain assigned by lewis on 18 Jan 2007 19:28

Reassigning this domain to its previous classification as part of fragment fixing process in preparation for release v3.1.0.

Insertion by lewis on 18 Jan 2007 19:28

Rechopping chains just before release v3.1.0 in order to fix missing fragments.