CATH Domain: 1hj9A02 XML data for domain: 1hj9A02

Molscript image for 1hj9A02
1hj9A02
PDB coordinates for domain 1hj9A02

PDB 1hj9, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.8
2.40.10.10.8.1
2.40.10.10.8.1.1
2.40.10.10.8.1.1.1
2.40.10.10.8.1.1.1.1

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Segment boundaries for domain 1hj9A02

Chopping figure for domain 1hj9A02
DomainStart PDB ResidueStop PDB Residue
1hj9A01 16 27
1hj9A01 121 232
1hj9A02 28 120
1hj9A02 233 245

Structural Neighbourhood (37 entries)

There are 37 matching structural neighberhood comparisons for CATH ID 2.40.10.10.8.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 37 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1hj8A02 96.80 Salmo salarTrypsin-1 2.40.10.10 103 63 100 0.56 0.56
2wphS02 93.53 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 42 95 1.44 1.51
1nn6A02 93.41 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 42 95 1.28 1.34
2qxiA02 93.26 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 44 94 1.17 1.24
1ym0A02 93.16 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 35 91 0.87 0.95
1a7sA02 93.15 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 31 97 0.92 0.95
2jkhA02 92.83 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 28 96 1.09 1.13
1orfA02 92.68 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 33 97 1.41 1.45
1eaxA02 92.42 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 35 88 1.33 1.50
1bioA02 92.17 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 33 95 1.00 1.05
3gylB02 91.93 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 33 91 1.21 1.32
1gvzA02 91.90 Equus caballusKallikrein-1E2 2.40.10.10 115 34 89 1.19 1.33
2asuB02 90.96 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 35 90 1.37 1.52
2bvrH02 90.88 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 116 33 87 0.92 1.06
2anyA02 90.85 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 33 91 2.26 2.46
1elvA01 90.75 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 27 86 1.50 1.74
2hlcA01 90.67 CollagenaseHypoderma lineatum 2.40.10.10 104 28 92 2.81 3.04
3beuA02 90.46 Streptomyces griseusTrypsin 2.40.10.10 99 24 91 1.80 1.97
1p57B02 90.35 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 32 84 1.30 1.53
2r0lA02 90.33 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 34 89 1.49 1.67
1q3xA03 90.31 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 27 90 1.59 1.76
1fiwA02 90.26 Ovis ariesAcrosinDrug binding 2.40.10.10 120 35 85 1.79 2.09
3govB02 90.05 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 33 82 2.01 2.42
2aiqA02 89.23 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 27 91 1.95 2.14
1gj7B02 88.81 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 28 85 1.39 1.62
1rrkA02 85.53 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 21 70 2.56 3.61
1p3cA02 84.93 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 16 89 2.40 2.67
2pkaA00 84.72 Sus scrofaGlandular kallikrein 2.40.10.10 80 30 65 1.33 2.04
1agjA02 84.27 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 14 85 2.59 3.04
2o8lA02 84.13 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 6 78 2.69 3.42
2qf3A01 81.24 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 10 68 3.08 4.47
2z9iC01 80.70 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 9 66 2.16 3.22
1lcyA01 80.38 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 13 69 2.44 3.52
1sotA01 80.27 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 11 69 2.66 3.83
2halA01 77.70 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 12 75 3.32 4.41
2hntC00 74.75 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 26 40 0.79 1.94
1eptA00 73.37 Sus scrofaTrypsin 2.40.10.10 43 69 30 0.24 0.80
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Displaying entries 1 to 37 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1hj9A02
PYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKS
AASLNSRVASNYVSWIKQTIASN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1hj9A02
PYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKS
AASLNSRVASNYVSWIKQTIASN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:26

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:26

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:46

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"