CATH Domain: 1hj8A02 XML data for domain: 1hj8A02

Molscript image for 1hj8A02
1hj8A02
PDB coordinates for domain 1hj8A02

PDB 1hj8, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.9
2.40.10.10.9.1
2.40.10.10.9.1.1
2.40.10.10.9.1.1.1
2.40.10.10.9.1.1.1.1

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Segment boundaries for domain 1hj8A02

Chopping figure for domain 1hj8A02
DomainStart PDB ResidueStop PDB Residue
1hj8A01 16 27
1hj8A01 121 232
1hj8A02 28 120
1hj8A02 233 245

Structural Neighbourhood (37 entries)

There are 37 matching structural neighberhood comparisons for CATH ID 2.40.10.10.9.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 37 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2wphS02 93.20 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 42 95 1.43 1.50
1a7sA02 93.17 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 31 97 1.08 1.11
2jkhA02 93.14 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 33 96 1.17 1.22
2qxiA02 93.10 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 41 94 1.29 1.37
1nn6A02 93.08 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 33 95 1.26 1.32
1orfA02 92.41 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 29 97 1.53 1.57
1ym0A02 92.38 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 33 91 0.86 0.94
1bioA02 92.12 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 38 95 1.11 1.16
1eaxA02 92.06 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 39 88 1.33 1.50
3gylB02 91.93 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 38 91 1.14 1.24
1gvzA02 91.82 Equus caballusKallikrein-1E2 2.40.10.10 115 32 89 1.38 1.54
1elvA01 90.75 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 30 86 1.21 1.40
2bvrH02 90.71 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 116 33 87 0.91 1.05
2hlcA01 90.55 CollagenaseHypoderma lineatum 2.40.10.10 104 30 92 2.75 2.98
2anyA02 90.47 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 33 91 2.20 2.39
2asuB02 90.23 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 33 90 1.32 1.46
2r0lA02 90.12 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 39 89 1.54 1.72
3beuA02 89.92 Streptomyces griseusTrypsin 2.40.10.10 99 25 91 1.77 1.94
1fiwA02 89.83 Ovis ariesAcrosinDrug binding 2.40.10.10 120 33 85 1.73 2.02
1q3xA03 89.77 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 29 90 1.59 1.76
3govB02 89.54 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 32 82 1.90 2.29
1p57B02 89.42 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 33 84 1.51 1.78
2aiqA02 89.07 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 28 91 1.96 2.15
1gj7B02 88.75 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 30 85 1.43 1.67
1rrkA02 85.27 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 25 70 2.49 3.51
1p3cA02 84.66 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 13 89 2.47 2.75
2pkaA00 84.65 Sus scrofaGlandular kallikrein 2.40.10.10 80 32 65 1.40 2.15
1agjA02 83.99 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 15 85 2.60 3.05
2o8lA02 83.83 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 8 78 2.79 3.55
1ky9A01 82.57 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 17 77 2.89 3.72
2qf3A01 81.09 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 9 68 3.16 4.58
1lcyA01 80.61 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 15 69 2.39 3.45
2z9iC01 80.16 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 91 10 66 2.37 3.54
1sotA01 79.60 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 9 69 2.89 4.16
2halA01 77.57 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 11 75 3.42 4.55
2hntC00 74.75 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 26 40 0.73 1.79
1eptA00 73.48 Sus scrofaTrypsin 2.40.10.10 43 60 30 0.32 1.06
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Displaying entries 1 to 37 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1hj8A02
PHQVSLNSGYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSK
PATLNTYVQPIFNDWLTSTMASY
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1hj8A02
PHQVSLNSGYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSK
PATLNTYVQPIFNDWLTSTMASY
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:46

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"