CATH Domain: 1gxtA00 XML data for domain: 1gxtA00

Molscript image for 1gxtA00
1gxtA00
PDB coordinates for domain 1gxtA00

PDB 1gxt, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.30 2-Layer Sandwich
3.30.70 Alpha-Beta Plaits
3.30.70.100 Gene3D
3.30.70.100.5
3.30.70.100.5.1
3.30.70.100.5.1.1
3.30.70.100.5.1.1.2
3.30.70.100.5.1.1.2.1

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Segment boundaries for domain 1gxtA00

Chopping figure for domain 1gxtA00
DomainStart PDB ResidueStop PDB Residue
1gxtA00 4 91

Structural Neighbourhood (86 entries)

There are 86 matching structural neighberhood comparisons for CATH ID 3.30.70.100.5.1.1.2.1 (SIMAX score < 5)

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Displaying entries 1 to 86 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2vh7A00 89.67 Acylphosphatase activityAcylphosphatase-1Pyruvate metabolismHomo sapiensPhosphate metabolic process 3.30.70.100 94 27 92 2.82 3.05
1y7pB01 83.06 Archaeoglobus fulgidusUncharacterized protein AF_1403 3.30.70.260 80 10 78 3.27 4.17
2f1fA01 82.71 Valine, leucine and isoleucine biosynthesisMetabolic pathwaysButanoate metabolismC5-Branched dibasic acid metabolismPantothenate and CoA biosynthesis 3.30.70.260 79 12 78 2.96 3.78
2oauA03 82.06 Small conductance mechanosensitive ion channel, MscS familySmall-conductance mechanosensitive channelMechanically-gated ion channel activityIntegral to membraneEscherichia coli K-12 3.30.70.100 86 6 73 2.50 3.38
2nyiA01 81.81 3.30.70.260 77 9 80 3.42 4.24
1lfpA03 81.60 UPF0082 protein aq_1575Aquifex aeolicus 3.30.70.980 73 6 80 2.63 3.26
2qmwA03 80.69 Phenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysPrephenate dehydratase [EC:4.2.1.51]Similar to chorismate mutaseStaphylococcus aureus subsp. aureus Mu50 3.30.70.260 73 10 70 2.40 3.41
1i1gA02 80.45 Pyrococcus furiosusHTH-type transcriptional regulator lrpALrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA 3.30.70.920 77 3 77 2.74 3.55
2qmxA03 80.26 Prephenate dehydratase [EC:4.2.1.51]Phenylalanine, tyrosine and tryptophan biosynthesisChlorobaculum tepidumMetabolic pathwaysPrephenate dehydratase 3.30.70.260 90 4 82 4.03 4.90
2nyiA02 80.21 3.30.70.260 89 7 83 3.72 4.47
2w25A02 80.10 Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory proteinLeucine-responsive regulatory proteinMycobacterium tuberculosis 3.30.70.920 81 7 76 3.02 3.97
1rwuA00 80.05 Hypothetical proteinUPF0250 protein ybeDEscherichia coli K-12 3.30.70.1460 87 8 76 3.60 4.73
1vi7A02 79.94 IMPACT family member yigZProtein bindingEscherichia coli K-12 3.30.70.240 71 11 76 3.73 4.90
2rhsD06 79.83 Aminoacyl-tRNA biosynthesisStaphylococcus haemolyticus JCSC1435Phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]Phenylalanyl-tRNA synthetase beta chain 3.30.70.380 88 7 70 2.37 3.36
1konA03 79.80 UPF0082 protein yebCEscherichia coli K-12 3.30.70.980 75 12 79 3.33 4.19
1r8hA00 79.40 Human papillomavirus type 6aRegulatory protein E2 3.30.70.330 87 10 81 3.15 3.85
1mwyA00 79.39 Cd2+/Zn2+-exporting ATPase [EC:3.6.3.3 3.6.3.5]Detoxification of zinc ionLead, cadmium, zinc and mercury-transporting ATPaseEscherichia coli K-12Response to cadmium ion 3.30.70.100 73 10 77 3.12 4.04
1u0sA00 79.29 Thermotoga maritimaBacterial chemotaxisTwo-component systemTwo-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]Protein binding 3.30.70.1110 86 8 79 3.52 4.43
1in0A01 79.21 Hypothetical proteinHaemophilus influenzaeUPF0234 protein HI_1034 3.30.70.860 70 7 77 2.37 3.07
1mw7A03 79.07 Helicobacter pyloriUPF0082 protein HP_0162 3.30.70.980 75 4 78 2.86 3.65
2ia0B02 78.81 Pyrococcus furiosusUncharacterized HTH-type transcriptional regulator PF0864 3.30.70.920 99 9 78 3.51 4.46
2nzcA00 78.80 Thermotoga maritimaPutative uncharacterized protein 3.30.70.1150 77 12 78 3.77 4.81
1s1tA02 78.68 HIV-1 M:B_HXB2RGag-Pol polyprotein 3.30.70.270 93 4 73 3.42 4.68
1u8sA01 78.58 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 86 11 87 3.64 4.16
1yx2A02 78.53 Nitrogen metabolismAminomethyltransferase [EC:2.1.2.10]One carbon pool by folateBacillus subtilisGlycine, serine and threonine metabolism 3.30.70.1400 81 6 71 3.09 4.32
2g9oA00 78.48 Cu2+-exporting ATPase [EC:3.6.3.4]Copper-dependent protein bindingCopper-transporting ATPase 1Trans-Golgi networkCellular copper ion homeostasis 3.30.70.100 77 9 79 3.44 4.32
1j27A00 78.37 Hypothetical proteinThermus thermophilusPutative uncharacterized protein 3.30.70.1120 98 9 79 3.67 4.61
1nu4A00 78.35 U1 small nuclear ribonucleoprotein ASpliceosomeSpliceosomal complexHomo sapiensProtein binding 3.30.70.330 91 5 85 3.40 3.97
2do0A01 78.30 Protein domain specific bindingIntegral to plasma membraneParaspecklesAlternative nuclear mRNA splicing, via spliceosomeHeterogeneous nuclear ribonucleoprotein M 3.30.70.330 76 2 76 2.65 3.48
2bopA00 78.25 Regulatory protein E2Bovine papillomavirus type 1 3.30.70.330 85 7 78 3.41 4.35
1nm2A01 78.24 Fatty acid biosynthesisStreptomyces coelicolorMalonyl CoA:acyl carrier protein malonyltransferase[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]Metabolic pathways 3.30.70.250 68 13 75 3.55 4.73
3bzqA00 78.16 Two-component systemNitrogen regulatory protein P-II 1Nitrogen regulatory protein P-IIMycobacterium tuberculosis 3.30.70.120 99 6 79 3.54 4.44
1fjeB01 78.16 NucleolinMesocricetus auratus 3.30.70.330 81 14 82 3.84 4.63
1u8sA02 78.14 Glycine cleavage system transcriptional repressor, putativeGlycine cleavage system transcriptional repressorVibrio cholerae 3.30.70.260 84 8 77 2.98 3.86
1earA02 78.13 Sporosarcina pasteuriiUrease accessory protein ureE 3.30.70.790 69 7 78 3.78 4.82
2fb0A00 78.05 Bacteroides thetaiotaomicronPutative uncharacterized protein 3.30.70.900 91 4 76 3.23 4.20
1wj9A01 78.00 Thermus thermophilus HB8Putative uncharacterized protein TTHB192 3.30.70.1200 87 8 72 3.21 4.41
1s99A02 77.91 Bacillus subtilisPutative HMP/thiamine-binding protein ykoF 3.30.70.930 81 6 80 3.87 4.80
1cvjA01 77.90 Poly(A) RNA bindingTranslation activator activityProtein C-terminus bindingMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 77 5 76 2.56 3.36
2od4B01 77.86 3.30.70.900 81 2 76 2.90 3.81
1mlaA01 77.80 Fatty acid biosynthesisMetabolic pathwaysMalonyl CoA-acyl carrier protein transacylase[acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]Escherichia coli K-12 3.30.70.250 73 9 78 2.85 3.63
2pehA01 77.66 Splicing factor 45SpliceosomeHomo sapiensProtein bindingSplicing factor 45 3.30.70.330 83 4 78 3.37 4.30
2pgcA01 77.65 3.30.70.900 95 5 77 3.37 4.33
2nuhA00 77.62 Xylella fastidiosaPeriplasmic divalent cation tolerance proteinPeriplasmic divalent cation tolerance protein 3.30.70.830 104 10 76 3.48 4.52
1eayD00 77.62 Bacterial chemotaxisTwo-component systemTwo-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]Escherichia coli K-12Chemotaxis protein cheA 3.30.70.400 69 13 73 3.07 4.16
1xtzA02 77.60 Identical protein bindingNucleusRibose-5-phosphate isomerasePyridoxine biosynthetic processRibose 5-phosphate isomerase A [EC:5.3.1.6] 3.30.70.260 84 5 72 3.40 4.67
3c19A01 77.57 Methanopyrus kandleriUncharacterized conserved protein 3.30.70.1380 98 7 78 3.60 4.58
1qupA01 77.55 [EC:4.2.-.-]NucleusProtein bindingSuperoxide dismutase copper chaperone activityCytosol 3.30.70.100 68 5 70 3.12 4.43
2vd3A03 77.53 Methanothermobacter thermautotrophicus str. Delta HATP phosphoribosyltransferaseATP phosphoribosyltransferase [EC:2.4.2.17]Histidine metabolismMetabolic pathways 3.30.70.120 74 6 73 3.02 4.09
1cvjG02 77.52 Poly(A) RNA bindingProtein C-terminus bindingTranslation activator activityMRNA polyadenylationPolyadenylate-binding protein 1 3.30.70.330 88 6 84 3.48 4.14
2pd1A01 77.44 Nitrosomonas europaeaPutative uncharacterized protein 3.30.70.900 93 13 82 3.53 4.26
1tr0A00 77.27 Populus tremulaStable protein 1 3.30.70.900 106 9 72 3.39 4.67
1nh8A03 77.27 Histidine metabolismMetabolic pathwaysATP phosphoribosyltransferaseATP phosphoribosyltransferase [EC:2.4.2.17]Mycobacterium tuberculosis 3.30.70.120 67 2 68 3.11 4.56
1no8A00 77.22 THO complex subunit 4Mus musculusSpliceosomeSingle-stranded DNA bindingRNA binding 3.30.70.330 78 10 76 3.21 4.22
1vlyA02 77.10 RNA modificationTRNA-modifying protein ygfZFolic acid bindingEscherichia coli K-12 3.30.70.1400 84 14 76 3.60 4.73
1mwqA00 77.08 Hypothetical proteinHaemophilus influenzaeUncharacterized protein HI_0828 3.30.70.1060 98 9 76 3.55 4.64
1jmtA00 76.87 Spliceosomal complexSplicing factor U2AF 35 kDa subunitCajal bodyHomo sapiensProtein binding 3.30.70.330 98 9 71 3.45 4.83
1tuvA00 76.81 Probable quinol monooxygenase ygiNProtein bindingEscherichia coli K-12 3.30.70.900 103 7 73 3.44 4.66
1l3kA01 76.65 Heterogeneous nuclear ribonucleoprotein A1NucleolusProtein bindingCytoplasmSpliceosome 3.30.70.330 84 9 80 3.02 3.74
1uw4A00 76.49 Regulator of nonsense transcripts 3BNuclear-transcribed mRNA catabolic process, nonsense-mediated decayHomo sapiensProtein binding 3.30.70.330 90 9 78 3.94 4.99
3bn7A00 76.45 Caulobacter vibrioidesPutative uncharacterized protein 3.30.70.900 96 9 72 3.41 4.68
1o8bA02 76.19 Pentose phosphate pathwayMetabolic pathwaysRibose 5-phosphate isomerase A [EC:5.3.1.6]Escherichia coli K-12Ribose-5-phosphate isomerase A 3.30.70.260 69 7 69 3.26 4.70
3bf4A01 76.10 Ralstonia eutropha JMP134Ethyl tert-butyl ether degradation EthD 3.30.70.900 92 2 71 3.10 4.32
1nzaA00 76.04 Thermus thermophilus HB8Divalent-cation tolerance protein cutAPeriplasmic divalent cation tolerance protein 3.30.70.830 103 9 76 3.37 4.39
2x3dF01 75.97 Hypothetical proteinSulfolobus solfataricusPutative uncharacterized protein 3.30.70.1340 84 4 82 3.89 4.69
2qyxB01 75.97 3.30.70.1360 109 7 66 3.19 4.83
1osdA00 75.95 Hypothetical periplasmic mercuric ion binding proteinCupriavidus metallidurans CH34 3.30.70.100 72 4 75 3.56 4.75
1l3kA02 75.78 Heterogeneous nuclear ribonucleoprotein A1NucleolusProtein bindingCytoplasmSpliceosome 3.30.70.330 78 6 77 3.18 4.12
3cjkB00 75.76 Cu2+-exporting ATPase [EC:3.6.3.4]Copper-dependent protein bindingCopper-transporting ATPase 1Cellular copper ion homeostasisTrans-Golgi network 3.30.70.100 75 5 81 3.69 4.51
2pgcA02 75.71 3.30.70.900 102 11 74 3.58 4.80
1x5uA01 75.67 SpliceosomeSpliceosomal complexHomo sapiensSplicing factor 3B subunit 4Splicing factor 3B subunit 4 3.30.70.330 80 7 79 3.74 4.70
1x5oA01 75.61 RNA processingHomo sapiensProtein bindingRNA-binding motif, single-stranded-interacting protein 1 3.30.70.330 86 4 81 3.69 4.51
2kt2A00 75.59 Mercuric reductasePseudomonas aeruginosaMercuric reductase [EC:1.16.1.1] 3.30.70.100 69 10 71 2.93 4.09
1fxlA02 75.52 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 77 10 75 3.70 4.93
2hzcA00 75.26 Splicing factor U2AF 65 kDa subunitSpliceosomeSpliceosomal complexSplicing factor U2AF 65 kDa subunitEnzyme binding 3.30.70.330 87 6 81 3.66 4.47
1sxlA00 75.10 Sex differentiationDrosophila melanogasterProtein complexPoly-pyrimidine tract bindingNegative regulation of translation 3.30.70.330 97 9 80 3.67 4.56
2hfvA01 74.99 Rhodopseudomonas palustrisPutative uncharacterized protein 3.30.70.790 77 6 70 3.29 4.67
2dgsA01 74.92 CytoplasmDAZ-associated protein 1NucleusRNA bindingHomo sapiens 3.30.70.330 89 5 82 3.39 4.13
1harA02 74.85 Human immunodeficiency virus type 1 BH10Gag-Pol polyprotein 3.30.70.270 69 7 70 3.12 4.43
1b7yB06 74.65 Aminoacyl-tRNA biosynthesisPhenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]Phenylalanyl-tRNA synthetase beta chainThermus thermophilus 3.30.70.380 86 6 69 3.35 4.83
2ofhX00 74.50 Cd2+/Zn2+-exporting ATPase [EC:3.6.3.3 3.6.3.5]Zinc-transporting ATPaseSynechocystis sp. PCC 6803 3.30.70.100 71 4 73 3.15 4.26
1sc6A03 74.42 Glycine, serine and threonine metabolismMetabolic pathwaysD-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]D-3-phosphoglycerate dehydrogenaseEscherichia coli K-12 3.30.70.260 79 11 80 3.82 4.73
2r4fA03 73.85 Terpenoid backbone biosynthesis3-hydroxy-3-methylglutaryl-coenzyme A reductaseGonad development3-hydroxy-3-methylglutaryl-CoA reductase [EC:1.1.1.34]Homo sapiens 3.30.70.420 117 9 66 3.20 4.80
2jwnA01 73.66 CytoplasmPoly(A) RNA bindingXenopus laevisEmbryonic polyadenylate-binding protein 2-B 3.30.70.330 100 4 71 3.39 4.77
1fxlA01 73.54 AU-rich element bindingELAV like protein 2/3/4MRNA processingHomo sapiensELAV-like protein 4 3.30.70.330 71 9 69 2.87 4.14
2j8sA03 73.36 Hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 familyAcriflavine resistance protein BProtein bindingEscherichia coli K-12 3.30.70.1320 100 3 76 3.52 4.63
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Displaying entries 1 to 86 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gxtA00
NTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLREDPEVFLVQLYQHCPPLARIDSVEREPFIWSQ
LPTEFTIR
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gxtA00
MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLREDPEVFLVQLYQHCPPLARIDSVEREPFI
WSQLPTEFTIR
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:59

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:59

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 15:26

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"