CATH Domain: 1gvkB02 XML data for domain: 1gvkB02

Molscript image for 1gvkB02
1gvkB02
PDB coordinates for domain 1gvkB02

PDB 1gvk, Chain B, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.1
2.40.10.10.1.1
2.40.10.10.1.1.1
2.40.10.10.1.1.1.1
2.40.10.10.1.1.1.1.1

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Segment boundaries for domain 1gvkB02

Chopping figure for domain 1gvkB02
DomainStart PDB ResidueStop PDB Residue
1gvkB01 16 27
1gvkB01 121 232
1gvkB02 28 120
1gvkB02 233 245

Structural Neighbourhood (40 entries)

There are 40 matching structural neighberhood comparisons for CATH ID 2.40.10.10.1.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 40 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2f91A02 93.31 Pontastacus leptodactylusHepatopancreas trypsin 2.40.10.10 112 31 95 1.13 1.18
1hj9A02 93.12 Neuroactive ligand-receptor interactionBos taurusCationic trypsinTrypsin [EC:3.4.21.4]Protein binding 2.40.10.10 103 43 91 0.95 1.03
2wphS02 92.57 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 37 96 1.89 1.96
3gylB02 92.51 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 111 31 93 1.22 1.30
1ym0A02 92.26 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 30 96 1.25 1.30
1bioA02 92.26 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 34 92 0.95 1.02
1hj8A02 92.18 Salmo salarTrypsin-1 2.40.10.10 103 37 91 1.13 1.23
2anyA02 92.10 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 29 96 2.21 2.29
1eaxA02 92.06 Suppressor of tumorigenicity protein 14 [EC:3.4.21.109]Integral to plasma membraneSuppressor of tumorigenicity 14 proteinHomo sapiensProteolysis 2.40.10.10 115 30 92 1.63 1.77
1gvzA02 91.85 Equus caballusKallikrein-1E2 2.40.10.10 115 29 92 1.36 1.48
1a7sA02 91.85 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 28 91 1.15 1.25
2jkhA02 91.72 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 31 93 1.15 1.23
1nn6A02 91.70 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 35 95 2.54 2.66
2bvrH02 91.23 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 116 31 92 1.30 1.41
1orfA02 91.22 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 29 92 1.78 1.92
1p57B02 90.97 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 33 87 1.42 1.63
1fiwA02 90.46 Ovis ariesAcrosinDrug binding 2.40.10.10 120 29 91 1.91 2.08
2r0lA02 90.20 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 26 92 1.55 1.68
2qxiA02 90.06 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 30 86 1.37 1.58
2asuB02 89.96 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 35 86 1.42 1.64
1gj7B02 89.81 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 27 93 1.68 1.80
3govB02 89.62 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 29 86 2.11 2.45
3beuA02 89.20 Streptomyces griseusTrypsin 2.40.10.10 99 28 85 2.20 2.57
2aiqA02 89.13 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 27 92 2.10 2.28
1q3xA03 88.92 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 28 85 1.67 1.95
1pq7A02 88.75 Fusarium oxysporumTrypsin 2.40.10.10 99 26 86 1.50 1.73
1elvA01 88.66 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 28 83 1.90 2.29
2hlcA01 88.49 CollagenaseHypoderma lineatum 2.40.10.10 104 27 91 3.68 4.00
1p3cA02 85.37 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 23 87 2.41 2.75
1rrkA02 85.34 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 18 76 3.14 4.08
1agjA02 84.28 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 17 84 2.52 2.97
2pkaA00 83.56 Sus scrofaGlandular kallikrein 2.40.10.10 80 32 60 1.37 2.26
2o8lA02 82.96 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 12 77 3.12 4.02
1ky9A01 82.37 Two-component systemSerine-type endopeptidase activityProtease doResponse to temperature stimulusProtein binding 2.40.10.10 88 19 72 2.43 3.36
1sotA01 81.27 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 9 75 3.13 4.15
1lcyA01 80.67 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 13 75 2.93 3.91
2qf3A01 80.59 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 102 9 69 3.14 4.51
2halA01 78.36 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 9 81 3.88 4.78
2hntC00 74.94 Serine-type endopeptidase activityFibrinolysisProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 67 26 41 1.22 2.91
1eptA00 69.47 Sus scrofaTrypsin 2.40.10.10 43 37 27 1.06 3.83
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Displaying entries 1 to 40 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gvkB02
PSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNNGTEQYVGVQKIVVHPYWNTDDVAAGY
DIALLRLAQSVTLNSYVQLAYISWINNVIASN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gvkB02
PSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNNGTEQYVGVQKIVVHPYWNTDDVAAGY
DIALLRLAQSVTLNSYVQLAYISWINNVIASN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:26

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:26

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:41

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"