CATH Domain: 1gsoA01 XML data for domain: 1gsoA01

Molscript image for 1gsoA01
1gsoA01
PDB coordinates for domain 1gsoA01

PDB 1gso, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.20 Gene3D
3.40.50.20.2
3.40.50.20.2.1
3.40.50.20.2.1.1
3.40.50.20.2.1.1.1
3.40.50.20.2.1.1.1.1

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Segment boundaries for domain 1gsoA01

Chopping figure for domain 1gsoA01
DomainStart PDB ResidueStop PDB Residue
1gsoA01 2 95
1gsoA02 121 190
1gsoA03 191 329
1gsoA04 330 425

Structural Neighbourhood (101 entries)

There are 101 matching structural neighberhood comparisons for CATH ID 3.40.50.20.2.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 101 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1vkzA01 86.32 Thermotoga maritimaPhosphoribosylamine--glycine ligase [EC:6.3.4.13]Purine metabolismPhosphoribosylamine--glycine ligaseMetabolic pathways 3.40.50.20 77 29 80 1.78 2.20
2x5oA01 83.26 D-Glutamine and D-glutamate metabolismPeptidoglycan biosynthesisMetabolic pathwaysUDP-N-acetylmuramoylalanine--D-glutamate ligaseUDP-N-acetylmuramoylalanine-D-glutamate ligase activity 3.40.50.720 92 16 85 2.47 2.90
1a9xA05 82.80 3.40.50.20 110 18 79 2.33 2.95
3eagA01 82.73 UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.-]Neisseria meningitidis serogroup BUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 3.40.50.720 88 20 87 2.81 3.22
1dv1B01 82.49 Pyruvate metabolismFatty acid biosynthesisPropanoate metabolismMetabolic pathwaysFatty acid biosynthetic process 3.40.50.20 85 12 75 1.99 2.63
1pjqA01 82.38 Porphyrin and chlorophyll metabolismSalmonella enterica subsp. enterica serovar TyphimuriumSiroheme synthaseUroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]Metabolic pathways 3.40.50.720 112 11 75 2.52 3.36
1mioB04 82.37 Nitrogenase molybdenum-iron protein beta chainClostridium pasteurianum 3.40.50.1980 98 13 88 3.03 3.41
1iowA01 81.90 D-Alanine metabolismPeptidoglycan biosynthesisD-alanine--D-alanine ligase BD-alanine-D-alanine ligase [EC:6.3.2.4]Escherichia coli K-12 3.40.50.20 84 5 74 2.56 3.44
3eq2B01 80.81 Pseudomonas aeruginosaProbable two-component response regulator 3.40.50.2300 103 14 69 2.61 3.73
1j6uA01 80.79 D-Glutamine and D-glutamate metabolismThermotoga maritimaUDP-N-acetylmuramate--L-alanine ligaseUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]Peptidoglycan biosynthesis 3.40.50.720 85 16 85 3.00 3.52
2ho3A01 80.73 Oxidoreductase, Gfo/Idh/MocA familyStreptococcus pneumoniae 3.40.50.720 113 17 75 2.87 3.82
1ulzA01 80.68 Pyruvate carboxylase subunit A [EC:6.4.1.1]Citrate cycle (TCA cycle)Pyruvate metabolismPyruvate carboxylase n-terminal domainAquifex aeolicus 3.40.50.20 129 15 70 2.18 3.09
1p3dA01 80.63 D-Glutamine and D-glutamate metabolismUDP-N-acetylmuramate--L-alanine ligaseUDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]Haemophilus influenzaePeptidoglycan biosynthesis 3.40.50.720 87 10 87 2.84 3.26
2aefA01 80.54 Methanothermobacter thermautotrophicus str. Delta HCalcium-gated potassium channel mthK 3.40.50.720 115 13 74 2.57 3.44
1m1nB03 80.47 Nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]Nitrogen metabolismAzotobacter vinelandiiNitrogenase molybdenum-iron protein beta chainMetabolic pathways 3.40.50.1980 106 10 83 3.18 3.83
3fdxA00 80.13 Putative uncharacterized protein ynaFKlebsiella pneumoniae subsp. pneumoniae MGH 78578 3.40.50.620 121 12 72 3.12 4.29
2pfsA01 80.12 Universal stress protein (Usp)Nitrosomonas europaeaUniversal stress protein A 3.40.50.620 114 9 78 3.01 3.86
2r85A01 79.66 Pyrococcus furiosus5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.-]Purine metabolism5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetaseMetabolic pathways 3.40.50.20 87 4 80 2.39 2.96
1tezA01 79.43 Deoxyribodipyrimidine photo-lyaseSynechococcus elongatus PCC 6301Deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 3.40.50.620 128 7 71 3.22 4.53
1v71A02 79.31 Serine racemaseSchizosaccharomyces pombe 3.40.50.1100 97 12 69 2.79 4.04
1mb3A00 79.18 Caulobacter vibrioidesTwo-component systemTwo-component system, cell cycle response regulator DivKPolar differentiation response regulatorCell cycle - Caulobacter 3.40.50.2300 115 9 61 2.53 4.10
1p5jA02 78.87 Protein homodimerization activityL-serine ammonia-lyase activityGlycine, serine and threonine metabolismPyruvate biosynthetic processMetabolic pathways 3.40.50.1100 96 10 70 2.75 3.88
1ep3B02 78.84 Lactococcus lactis subsp. cremoris MG1363Dihydroorotate dehydrogenase electron transfer subunitProtein bindingDihydroorotate dehydrogenase electron transfer subunit 3.40.50.80 117 10 74 2.78 3.74
1efdN01 78.76 ABC transportersIron(3+)-hydroxamate-binding protein fhuDIron complex transport system substrate-binding proteinEscherichia coli K-12 3.40.50.1980 91 8 86 3.15 3.66
1g7sA03 78.60 Methanothermobacter thermautotrophicus str. Delta HTranslation initiation factor IF-2 unclassified subunitProbable translation initiation factor IF-2 3.40.50.10050 81 11 77 3.05 3.93
2iksA01 78.45 LacI family transcriptional regulator, fructose operon transcriptional repressorFructose repressorEscherichia coli K-12 3.40.50.2300 95 10 81 3.27 4.03
1dnpA01 78.45 Protein-chromophore linkageDeoxyribodipyrimidine photo-lyaseDeoxyribodipyrimidine photo-lyase activityProtein bindingDeoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 3.40.50.620 130 8 69 3.46 5.00
3dloD00 78.33 Archaeoglobus fulgidusPutative uncharacterized protein 3.40.50.620 131 11 67 3.07 4.52
2q5cA02 78.27 Clostridium acetobutylicumNtrC family transcriptional regulator (PAS and AAA domains) 3.40.50.10660 89 12 76 3.35 4.37
1lssA00 78.26 Trk system potassium uptake protein TrkATrk system potassium uptake protein trkA homologMethanocaldococcus jannaschii 3.40.50.720 132 13 68 2.71 3.97
1zgzA00 78.20 Two-component systemTorCAD operon transcriptional regulatory protein torRTwo-component system, OmpR family, torCAD operon response regulator TorRProtein bindingEscherichia coli K-12 3.40.50.2300 118 13 61 2.79 4.57
2qzjA00 78.15 Two-component response regulatorClostridium difficile 630 3.40.50.2300 119 10 60 2.55 4.21
1a9xA08 78.13 3.40.50.1380 106 9 84 3.96 4.66
3fwzA00 78.10 Inner membrane protein ybaLMonovalent cation:H+ antiporter-2, CPA2 familyEscherichia coli K-12 3.40.50.720 137 15 64 2.70 4.20
3cnbA00 78.10 DNA-binding response regulator, merR familyColwellia psychrerythraea 34H 3.40.50.2300 124 7 60 2.50 4.13
2pjuA02 78.04 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 3.40.50.10660 88 9 72 3.32 4.59
1srrC00 78.03 Sporulation initiation phosphotransferase FTwo-component system, response regulator, stage 0 sporulation protein FBacillus subtilisTwo-component system 3.40.50.2300 121 12 60 2.85 4.72
2qr3A00 77.95 Bacteroides fragilisTwo-component system response regulator 3.40.50.2300 119 6 60 2.61 4.31
1bxrA05 77.92 3.40.50.20 140 18 62 2.25 3.62
1yqeA02 77.81 Hypothetical proteinArchaeoglobus fulgidusD-tyrosyl-tRNA(Tyr) deacylase 3.40.50.10700 96 6 84 4.19 4.97
1pl8A02 77.67 Membrane fractionZinc ion bindingL-iditol 2-dehydrogenase [EC:1.1.1.14]Sorbitol catabolic processGlucose metabolic process 3.40.50.720 139 18 66 3.32 4.96
1j0aA02 77.66 1-aminocyclopropane-1-carboxylate deaminase [EC:3.5.99.7]Pyrococcus horikoshiiPropanoate metabolismPutative 1-aminocyclopropane-1-carboxylate deaminase 3.40.50.1100 104 7 64 2.56 3.97
2b4aA00 77.58 BH3024 proteinBacillus halodurans 3.40.50.2300 116 10 63 2.59 4.06
1iibA00 77.53 Phosphotransferase system (PTS)N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB componentPTS system, cellobiose-specific IIB component [EC:2.7.1.69]Escherichia coli K-12 3.40.50.270 103 8 66 3.15 4.70
2pjuC01 77.48 Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity 3.40.50.2300 100 4 73 3.09 4.23
2gfqA02 77.35 Hypothetical proteinPyrococcus horikoshiiD-tyrosyl-tRNA(Tyr) deacylase 3.40.50.10700 87 12 84 3.60 4.28
1p2fA01 77.30 Thermotoga maritimaResponse regulatorTwo-component system, OmpR family, response regulator 3.40.50.2300 117 8 58 2.63 4.46
3gl9B00 77.26 Thermotoga maritimaResponse regulatorTwo-component system, unclassified family, response regulatorProtein binding 3.40.50.2300 118 9 61 2.83 4.57
1dz3A00 77.23 Geobacillus stearothermophilusStage 0 sporulation protein A 3.40.50.2300 123 12 60 3.03 4.97
1xeaA01 77.16 Vibrio choleraeOxidoreductase, Gfo/Idh/MocA familyVirulence factor 3.40.50.720 117 14 68 3.13 4.58
3b2nA00 77.13 Similar to two-component response regulatorStaphylococcus aureus subsp. aureus Mu50 3.40.50.2300 119 8 63 2.78 4.41
3cg0A00 77.07 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor 3.40.50.2300 121 12 60 2.98 4.94
2zayA00 76.86 Response regulator receiver proteinDesulfuromonas acetoxidans DSM 684 3.40.50.2300 123 6 59 2.60 4.38
2qsjB00 76.85 DNA-binding response regulator, LuxR familyRuegeria pomeroyi 3.40.50.2300 122 8 58 2.81 4.83
1jbeA00 76.73 Bacterial chemotaxisTwo-component systemEscherichia coli O157:H7Two-component system, chemotaxis family, response regulator CheYChemotaxis protein cheY 3.40.50.2300 125 13 59 2.65 4.48
2hmtA00 76.68 Trk system potassium uptake protein TrkABacillus subtilisKtr system potassium uptake protein A 3.40.50.720 139 14 63 2.73 4.31
2q5cA01 76.64 Clostridium acetobutylicumNtrC family transcriptional regulator (PAS and AAA domains) 3.40.50.2300 97 7 71 2.86 4.02
1qfjA02 76.62 Porphyrin and chlorophyll metabolismAquacobalamin reductase / NAD(P)H-flavin reductase [EC:1.16.1.3 1.5.1.29]NAD(P)H-flavin reductaseEscherichia coli K-12 3.40.50.80 135 15 69 3.47 4.98
1f2dA02 76.55 Williopsis saturnus1-aminocyclopropane-1-carboxylate deaminase 3.40.50.1100 102 8 69 3.09 4.44
1qtqA05 76.52 Aminoacyl-tRNA biosynthesisMetabolic pathwaysGlutaminyl-tRNA synthetaseGlutamine-tRNA ligase activityGlutaminyl-tRNA aminoacylation 3.40.50.620 123 3 72 3.22 4.45
1dljA02 76.52 Amino sugar and nucleotide sugar metabolismStarch and sucrose metabolismPentose and glucuronate interconversionsAscorbate and aldarate metabolismMetabolic pathways 3.40.50.1870 108 6 70 3.41 4.85
2r7kA01 76.36 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.-]Purine metabolismMethanocaldococcus jannaschii5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetaseMetabolic pathways 3.40.50.20 111 5 73 2.55 3.45
3gt7A00 76.34 Sensor proteinSyntrophus aciditrophicus SB 3.40.50.2300 131 6 54 2.26 4.17
2jbaA00 76.21 Two-component systemPhosphate regulon transcriptional regulatory protein phoBTwo-component system, OmpR family, phosphate regulon response regulator PhoBProtein bindingEscherichia coli K-12 3.40.50.2300 125 8 58 2.61 4.47
2p2sA01 76.16 Pectobacterium atrosepticumPutative oxidoreductase 3.40.50.720 130 15 64 2.78 4.30
1id1A00 76.14 Voltage-gated potassium channel activityVoltage-gated potassium channelPotassium ion transportPutative potassium channel proteinEscherichia coli K-12 3.40.50.720 153 11 58 2.86 4.86
3ceaA01 76.04 Lactobacillus plantarumStreptomycin biosynthesisMyo-inositol 2-dehydrogenaseMyo-inositol 2-dehydrogenase [EC:1.1.1.18]Inositol phosphate metabolism 3.40.50.720 143 15 58 2.70 4.60
1s8nA01 75.98 Response regulator NasTProbable transcriptional regulatory protein pdtaRMycobacterium tuberculosis 3.40.50.2300 132 14 56 2.41 4.30
1ve1A02 75.97 Thermus thermophilus HB8Cysteine synthase A [EC:2.5.1.47]Selenoamino acid metabolismCysteine synthaseSulfur metabolism 3.40.50.1100 108 7 61 2.61 4.27
2eggA02 75.95 Shikimate 5-dehydrogenase [EC:1.1.1.25]Geobacillus kaustophilusPhenylalanine, tyrosine and tryptophan biosynthesisShikimate 5-dehydrogenaseMetabolic pathways 3.40.50.720 140 11 61 3.01 4.90
3fg9C01 75.80 Putative uncharacterized protein lp_3663Lactobacillus plantarum 3.40.50.620 133 12 66 3.13 4.68
1lu9A02 75.79 Methylobacterium extorquens AM1Bifunctional protein mdtA 3.40.50.720 151 9 58 2.89 4.96
2g76A01 75.67 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]D-3-phosphoglycerate dehydrogenaseGlycine, serine and threonine metabolismBrain developmentMetabolic pathways 3.40.50.720 112 11 58 2.20 3.73
2jk1A00 75.57 Hydrogenase transcriptional regulatory protein hupR1Rhodobacter capsulatus 3.40.50.2300 138 8 52 2.53 4.85
2driA01 75.57 Bacterial chemotaxisABC transportersD-ribose-binding periplasmic proteinRibose transport system substrate-binding proteinMembrane 3.40.50.2300 125 9 64 3.14 4.91
1n2zA01 75.57 ABC transportersPeriplasmic spaceVitamin B12-binding proteinCobalamin bindingVitamin B12 transport system substrate-binding protein 3.40.50.1980 119 17 70 3.37 4.77
2qxyA00 75.56 Thermotoga maritimaResponse regulatorTwo-component system, unclassified family, response regulator 3.40.50.2300 118 14 61 2.61 4.28
2dwuA02 75.54 D-Glutamine and D-glutamate metabolismMetabolic pathwaysBacillus anthracisGlutamate racemaseGlutamate racemase [EC:5.1.1.3] 3.40.50.1860 113 14 66 2.93 4.41
1a04A01 75.44 Two-component systemTwo-component system, NarL family, nitrate/nitrite response regulator NarLProtein bindingEscherichia coli K-12Nitrate/nitrite response regulator protein narL 3.40.50.2300 124 12 60 2.95 4.88
1w25B02 75.37 Two-component systemCell cycle - CaulobacterCaulobacter vibrioidesIdentical protein bindingTwo-component system, cell cycle response regulator 3.40.50.2300 143 11 49 2.42 4.87
1jflA02 75.32 Aspartate racemase [EC:5.1.1.13]228aa long hypothetical aspartate racemasePyrococcus horikoshiiAlanine, aspartate and glutamate metabolism 3.40.50.1860 109 8 70 2.98 4.22
1v7cA02 75.23 Threonine synthase [EC:4.2.3.1]Vitamin B6 metabolismGlycine, serine and threonine metabolismThreonine synthaseMetabolic pathways 3.40.50.1100 97 10 70 3.44 4.91
1ny5A01 75.16 Transcriptional regulator (NtrC family)Two-component system, NtrC family, response regulatorAquifex aeolicus 3.40.50.2300 136 7 53 2.35 4.38
2r25B00 75.12 MAPK signaling pathway - yeastResponse to hydrogen peroxideProtein bindingOsmosensor activityOsomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3] 3.40.50.2300 131 8 58 2.57 4.43
1ydwA01 75.05 Arabidopsis thalianaUncharacterized oxidoreductase At4g09670 3.40.50.720 124 12 69 3.29 4.74
2ielA00 75.04 Thermus thermophilus HB27Putative uncharacterized protein 3.40.50.620 132 9 69 3.42 4.91
3bulA02 75.02 One carbon pool by folateMetabolic pathwaysCysteine and methionine metabolismEscherichia coli K-12Methionine synthase activity 3.40.50.280 153 8 49 2.25 4.59
1q77A00 75.02 Uncharacterized protein aq_178Aquifex aeolicus 3.40.50.620 137 7 66 3.14 4.73
1nvmB01 74.88 Pseudomonas sp. CF600Acetaldehyde dehydrogenase (Acylating) 3.40.50.720 158 19 56 2.59 4.60
3c85A00 74.71 Vibrio parahaemolyticusPutative glutathione-regulated potassium-efflux system protein KefB 3.40.50.720 148 10 60 2.82 4.64
1sr8A03 74.50 Porphyrin and chlorophyll metabolismArchaeoglobus fulgidusCobalamin biosynthesis protein CbiDPutative cobalt-precorrin-6A synthase [deacetylating]Metabolic pathways 3.40.50.10720 90 6 71 3.24 4.55
1hyeA01 74.48 Malate dehydrogenase [EC:1.1.1.37]Citrate cycle (TCA cycle)Methanocaldococcus jannaschiiPyruvate metabolismMetabolic pathways 3.40.50.720 147 17 58 2.91 4.97
2c82A01 74.40 Terpenoid backbone biosynthesisMetabolic pathways1-deoxy-D-xylulose 5-phosphate reductoisomerase1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]Mycobacterium tuberculosis 3.40.50.720 141 12 65 3.21 4.87
2eklA01 74.34 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95]Sulfolobus tokodaiiGlycine, serine and threonine metabolismMetabolic pathways313aa long hypothetical D-3-phosphoglycerate dehydrogenase 3.40.50.720 121 11 54 2.47 4.53
1yl5A01 74.21 Metabolic pathwaysLysine biosynthesisDihydrodipicolinate reductase [EC:1.3.1.26]Dihydrodipicolinate reductaseMycobacterium tuberculosis 3.40.50.720 140 10 52 2.54 4.87
3a06B01 73.63 Terpenoid backbone biosynthesisThermotoga maritima1-deoxy-D-xylulose 5-phosphate reductoisomerase1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]Metabolic pathways 3.40.50.720 141 8 65 3.23 4.90
1ad2A02 73.57 RibosomeLarge subunit ribosomal protein L150S ribosomal protein L1Thermus thermophilus 3.40.50.790 93 12 70 3.32 4.73
3cs3A01 73.53 Sugar-binding transcriptional regulator, LacI familyLacI family transcriptional regulatorEnterococcus faecalis 3.40.50.2300 122 11 59 2.50 4.24
2hqbA01 73.43 Transcriptional activator of comK geneTranscriptional activator of comK geneBacillus halodurans 3.40.50.2300 130 7 58 2.49 4.26
3d8uB01 72.20 Putative transcriptional regulatorVibrio parahaemolyticusLacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor 3.40.50.2300 119 4 63 3.14 4.98
3brqB01 71.25 Negative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activityHTH-type transcriptional regulator ascGSequence-specific DNA binding transcription factor activity 3.40.50.2300 127 12 60 3.00 4.95
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Displaying entries 1 to 101 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gsoA01
KVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQNVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVV
DTFRAAGLKIFGPT
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gsoA01
KVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQNVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVV
DTFRAAGLKIFGPT
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 19:12

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 19:12

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:40

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"