CATH Domain: 1gl2C00 XML data for domain: 1gl2C00

Molscript image for 1gl2C00
1gl2C00
PDB coordinates for domain 1gl2C00

PDB 1gl2, Chain C, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.9
1.20.5.110.9.1
1.20.5.110.9.1.1
1.20.5.110.9.1.1.1
1.20.5.110.9.1.1.1.1

Segment boundaries for domain 1gl2C00

Chopping figure for domain 1gl2C00
DomainStart PDB ResidueStop PDB Residue
1gl2C00 139 198

Structural Neighbourhood (87 entries)

There are 87 matching structural neighberhood comparisons for CATH ID 1.20.5.110.9.1.1.1.1 (SIMAX score < 5)

Displaying entries 1 to 87 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1jocA01 91.47 Zinc ion bindingVesicle fusionMembrane fractionSynaptic vesicle to endosome fusionProtein homodimerization activity 1.20.5.390 60 3 95 1.26 1.33
1ci6A00 89.98 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 8 93 1.89 2.03
1gl2D00 89.80 Syntaxin-8Rattus norvegicusProtein bindingSyntaxin 8SNARE interactions in vesicular transport 1.20.5.110 54 14 86 1.27 1.47
1ybkA00 88.86 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 11 88 1.73 1.96
1jcdB00 88.79 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 7 84 1.17 1.38
1ik7A00 88.23 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 5 88 1.72 1.95
1r8eA03 88.15 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 18 74 1.07 1.43
1gmjD00 88.13 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 10 93 2.73 2.93
2e42A00 88.11 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 15 80 1.53 1.91
1a02F00 88.09 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 7 86 1.72 1.99
1svfC00 87.71 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 6 95 2.75 2.89
1pl5A00 87.69 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 13 73 0.99 1.35
1gk4C00 87.51 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 6 84 1.47 1.74
1nknA00 87.33 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 10 79 1.52 1.91
1e5wA04 87.24 Leukocyte migrationReceptor bindingCytoskeletonMembrane to membrane dockingNucleolus 1.20.5.450 55 10 93 3.61 3.87
1ezjA02 87.19 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 1 72 1.21 1.66
2b9bA04 86.95 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 11 72 1.56 2.15
1ic2B00 86.80 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 16 76 1.23 1.61
2w83C00 86.32 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 6 64 0.92 1.43
1gu4A00 86.00 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 10 83 2.15 2.59
1n2dC00 85.12 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 10 79 2.37 2.98
2p7jB01 84.28 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 12 59 1.05 1.77
1gd2F00 84.24 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 8 92 4.43 4.81
1jekA00 84.16 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 20 67 1.47 2.17
2p2uA01 83.69 Desulfovibrio vulgaris str. HildenboroughHost-nuclease inhibitor protein Gam, putative 1.20.5.170 69 10 84 3.24 3.85
2basA02 83.60 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 2 76 2.40 3.15
1czqA00 83.46 1.20.5.170 45 6 55 1.07 1.91
3effK02 83.15 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 6 69 1.84 2.65
1hf9A00 83.05 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 12 69 1.42 2.04
1ifpA00 83.02 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 11 74 2.30 3.08
1favA00 82.72 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 6 62 1.04 1.66
1pfiA00 82.65 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 6 74 2.55 3.42
2o1kA00 82.41 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 7 71 2.04 2.87
1kv4A00 82.31 Moricin-1Bombyx mori 1.20.5.750 42 2 71 2.66 3.74
2zvoB00 81.88 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 6 67 1.78 2.65
1nhlA00 81.87 Vesicle targetingAzurophil granuleCellular membrane fusionSynaptosomal-associated protein 23Protein binding 1.20.5.110 52 3 67 2.16 3.19
3kpeA00 81.74 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 2 79 2.93 3.68
1kilE00 81.71 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 7 62 1.90 3.03
1gk6B00 81.66 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 3 62 1.67 2.66
1wt6B00 81.62 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 6 58 1.30 2.23
1rh5B00 81.56 Protein transport protein SEC61 subunit gamma and related proteinsProtein exportMethanocaldococcus jannaschiiPreprotein translocase subunit secE 1.20.5.820 56 5 67 3.32 4.90
1uixA00 81.28 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 10 75 3.24 4.32
3cx5E01 81.08 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 5 67 2.61 3.85
1gl2A00 80.73 Rattus norvegicusProtein complex assemblyVesicle-associated membrane protein 8Cellular membrane fusionVesicle-associated membrane protein 8 1.20.5.110 53 5 55 1.12 2.00
1tiiC00 80.36 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 5 61 2.17 3.56
1d7mA00 79.75 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 11 58 1.84 3.15
1mg1A03 79.70 Bacterial chemotaxisABC transportersMaltose/maltodextrin transport system substrate-binding proteinEscherichia coli O157:H7Maltose-binding periplasmic protein 1.10.287.210 84 1 61 2.84 4.59
1sfcH00 78.94 SNARE interactions in vesicular transportSleepRattus norvegicusRegulation of synaptogenesisVoltage-gated potassium channel complex 1.20.5.110 72 10 63 2.74 4.29
1m56D00 78.51 Rhodobacter sphaeroidesAa3-type cytochrome c oxidase subunit IV 1.20.5.160 42 2 67 3.02 4.45
1slqF02 78.31 Outer capsid protein VP4Rhesus rotavirus 1.20.5.170 32 9 54 2.29 4.22
1piqA00 78.18 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 6 49 1.25 2.54
2zxeB01 78.13 1.20.5.170 35 5 47 1.03 2.17
1t3jA00 77.62 Mus musculusMitochondrial fusionMitofusin-1Protein binding 1.20.5.110 62 3 48 1.29 2.67
2h8pD00 77.42 1.20.5.110 43 11 47 1.21 2.55
3efgA00 76.99 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 6 59 2.17 3.66
2r44A01 76.77 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 15 44 0.69 1.57
1dp5B00 76.69 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 6 52 1.98 3.77
1go9A00 76.48 1.20.5.480 39 5 54 2.46 4.54
1fdoA05 76.34 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 14 45 1.59 3.47
1aa0A00 76.21 Enterobacteria phage T4Fibritin 1.20.5.320 113 1 52 2.36 4.52
1dkgA01 76.12 Protein grpEResponse to heatMolecular chaperone GrpEEscherichia coli K-12 3.90.20.20 98 10 60 2.42 4.02
1ik9B02 76.04 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 8 57 2.46 4.25
2ifoA00 75.86 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 6 55 2.27 4.06
1vf5C03 75.24 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 3 40 0.95 2.34
1jmmA01 75.11 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 3 47 1.63 3.43
1j2jB00 74.15 ADP-ribosylation factor-binding protein GGA1Homo sapiensProtein bindingIntracellular protein transport 1.20.5.170 41 4 40 0.82 2.02
1vl2A03 73.89 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 32 12 50 2.48 4.88
2p1jA02 73.76 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 7 44 2.13 4.83
3ii6A02 73.70 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 1 52 2.17 4.13
1vl2B03 73.69 Thermotoga maritimaArginine and proline metabolismArgininosuccinate synthase [EC:6.3.4.5]Alanine, aspartate and glutamate metabolismArgininosuccinate synthase 1.20.5.470 30 13 50 2.48 4.88
2oarE02 73.52 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 9 37 1.51 4.05
2qjyC01 73.42 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 12 45 1.67 3.65
1h8bB00 73.14 TitinOryctolagus cuniculus 1.20.5.510 23 4 38 1.77 4.54
1j1dF01 72.68 Protein domain specific bindingCardiac muscle contractionDilated cardiomyopathyActin bindingNegative regulation of ATPase activity 1.20.5.350 102 11 37 1.16 3.11
3clqB01 72.48 Enterococcus faecalisPutative uncharacterized protein 1.20.5.220 24 8 35 0.91 2.56
1omiA02 72.40 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 14 37 1.34 3.59
2pp6A01 71.07 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 4 35 0.87 2.44
1be3K00 70.82 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 9 37 1.60 4.29
3c8vA04 70.55 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 0 32 0.64 1.99
2p10B02 70.47 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 11 40 1.35 3.32
2wwwC01 68.97 Methylmalonic aciduria type A protein, mitochondrialHomo sapiensLAO/AO transport system kinase [EC:2.7.-.-] 1.20.5.170 52 1 35 1.37 3.85
2rh0A02 68.67 Mus musculusNudC domain-containing protein 2 1.20.5.740 29 3 32 0.95 2.95
1kmiZ02 68.42 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.10.287.500 134 8 38 1.66 4.36
2oarA02 68.05 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 28 0.53 1.84
2i8dA02 66.69 Hypothetical proteinLactobacillus casei ATCC 334Putative uncharacterized protein 1.20.5.420 30 3 30 1.21 3.97
1mslA02 62.70 1.20.5.220 18 11 25 0.89 3.50
1mkmA02 60.64 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 7 23 0.61 2.57
Displaying entries 1 to 87 (page 1 of 1)


Domain ATOM Sequence

>pdb|1gl2C00
MNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSM    

Domain COMBS Sequence

>pdb|1gl2C00
GSHMNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSR    

Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"