CATH Domain: 1gl2A00 XML data for domain: 1gl2A00

Molscript image for 1gl2A00
1gl2A00
PDB coordinates for domain 1gl2A00

PDB 1gl2, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.110 Gene3D
1.20.5.110.11
1.20.5.110.11.1
1.20.5.110.11.1.1
1.20.5.110.11.1.1.1
1.20.5.110.11.1.1.1.1

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Segment boundaries for domain 1gl2A00

Chopping figure for domain 1gl2A00
DomainStart PDB ResidueStop PDB Residue
1gl2A00 11 64

Structural Neighbourhood (91 entries)

There are 91 matching structural neighberhood comparisons for CATH ID 1.20.5.110.11.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 91 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1gk6B00 91.70 Positive regulation of RNA polymerase II transcriptional preinitiation complex assemblyIntermediate filamentVimentinCytosolPositive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.170 52 11 86 0.72 0.83
3gwoA00 90.24 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 9 86 1.27 1.46
1a02F00 89.27 Promoter bindingPathways in cancerChagas diseaseProto-oncogene protein c-fosB cell receptor signaling pathway 1.20.5.170 53 11 98 2.43 2.48
1gd2F00 88.69 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 5 82 1.62 1.96
1r8eA03 88.58 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 13 83 1.64 1.98
1ybkA00 88.42 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 5 81 1.57 1.94
2o1kA00 88.13 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 9 79 1.08 1.36
1gmjD00 88.03 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 7 82 1.85 2.25
1czqA00 88.02 1.20.5.170 45 8 84 1.73 2.04
1kilE00 87.87 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 0 77 1.51 1.95
1n2dC00 87.86 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 2 81 1.46 1.80
1t3jA00 87.41 Mus musculusMitochondrial fusionMitofusin-1Protein binding 1.20.5.110 62 5 77 1.64 2.12
3kpeA00 87.31 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 6 81 1.69 2.08
1gk4C00 87.30 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 5 75 1.50 1.98
1nwqA00 87.09 Protein domain specific bindingRattus norvegicusAcute-phase responsePathways in cancerOrgan regeneration 1.20.5.170 60 5 83 2.08 2.50
1l2pA00 86.79 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 1 83 2.82 3.37
1jekA00 86.59 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 12 75 1.51 2.00
2w83C00 86.43 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 9 79 1.61 2.04
1ci6A00 86.31 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 9 75 1.77 2.36
1l4aA00 86.01 SynaptobrevinLoligo pealei 1.20.5.110 66 13 78 1.48 1.88
2e42A00 85.82 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 1 78 3.03 3.86
1nhlA00 85.80 Vesicle targetingAzurophil granuleCellular membrane fusionSynaptosomal-associated protein 23Protein binding 1.20.5.110 52 5 77 1.09 1.41
1favA00 85.75 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 13 67 0.96 1.41
1ezjA02 85.53 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 3 77 2.28 2.95
1jcdB00 85.25 Peptidoglycan bindingMurein lipoproteinMajor outer membrane lipoprotein LppProtein bindingEscherichia coli K-12 1.20.5.190 52 7 90 3.82 4.22
1nkzB00 85.13 Rhodoblastus acidophilusLight-harvesting protein B-800/850 beta chain 1.20.5.250 41 4 66 2.61 3.95
2p7jB01 85.02 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 5 73 1.85 2.51
1dh3A00 84.86 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 1 76 1.57 2.06
3effK02 84.66 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 6 71 1.46 2.04
1g2cB00 84.61 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 7 66 1.19 1.80
2b9bA04 84.44 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 13 72 2.47 3.40
2ifoA00 83.80 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 10 86 2.87 3.31
1llmD02 83.73 Early growth response protein 1Prion diseasesPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyResponse to insulin stimulusNegative regulation of transcription from RNA polymerase II promoter 3.30.160.60 55 7 78 3.20 4.09
3efgA00 83.45 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 8 67 2.46 3.62
1a2xB00 83.43 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 6 58 0.69 1.18
1jnmA00 83.15 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 3 55 0.60 1.08
1ifpA00 83.15 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 6 67 1.61 2.37
1kv4A00 83.12 Moricin-1Bombyx mori 1.20.5.750 42 4 77 2.56 3.31
3cx5E01 82.57 Cytochrome b-c1 complex subunit Rieske, mitochondrialMitochondrial respiratory chain complex IIIOxidative phosphorylationMetabolic pathwaysAerobic respiration 1.20.5.270 55 3 63 1.28 2.01
1piqA00 82.26 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 9 52 0.51 0.97
1hf9A00 82.25 Protein homodimerization activityNegative regulation of hydrolase activityATPase inhibitor activityBos taurusATPase binding 1.20.5.500 41 14 62 1.43 2.30
1junA00 82.09 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 4 69 2.38 3.41
1svfC00 81.98 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 1 64 2.05 3.18
2p2uA01 81.89 Desulfovibrio vulgaris str. HildenboroughHost-nuclease inhibitor protein Gam, putative 1.20.5.170 69 5 75 1.72 2.28
1ci6B00 80.95 Mammary gland epithelial cell differentiationMammary gland epithelial cell proliferationCytoplasmProtein heterodimerization activitySequence-specific enhancer binding RNA polymerase II transcription factor activity 1.20.5.170 47 17 75 3.47 4.60
1d7mA00 80.59 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 11 49 1.08 2.18
1pl5A00 80.39 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 9 54 1.50 2.74
1j1dB00 80.36 Response to calcium ionTroponin C bindingPositive regulation of ATPase activityActin bindingNegative regulation of ATPase activity 1.20.5.350 70 5 68 2.66 3.88
1fjkA00 80.17 Calcium signaling pathwayDilated cardiomyopathySus scrofaCardiac phospholambanPhospholamban 1.20.5.290 52 3 62 1.46 2.34
1ohhG00 80.12 Bos taurusATP synthase subunit gamma, mitochondrialProtein binding 1.10.287.80 94 9 55 1.26 2.28
1jmmA01 80.10 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 15 60 1.71 2.83
1m7lA00 80.07 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 10 69 2.48 3.55
1tiiC00 79.97 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 2 50 1.64 3.22
2basA02 79.90 Bacillus subtilisUncharacterized EAL-domain containing protein ykuI 1.20.5.170 46 4 73 3.42 4.65
1dp5B00 79.72 CytoplasmProtease A inhibitor 3Saccharomyces cerevisiaeVacuolar protein catabolic processProtein binding 1.20.5.140 31 6 58 1.82 3.11
2r44A01 79.58 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 7 49 0.59 1.20
1vf5C03 79.41 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 0 60 1.96 3.25
3e7kA00 79.14 Rattus norvegicusCalcium channel activityCalcium ion transportIntegral to membraneProtein binding 1.20.5.1010 54 1 55 1.43 2.57
1omiA02 78.99 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 3 50 0.97 1.90
1ic2B00 78.49 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 13 46 0.88 1.88
1ytzT00 78.47 Troponin T, fast skeletal muscle isoformsGallus gallus 1.20.5.350 90 9 56 1.76 3.11
2qjyC01 78.42 Oxidative phosphorylationMetabolic pathwaysRhodobacter sphaeroidesUbiquinol-cytochrome c reductase iron-sulfur subunitUbiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] 1.20.5.510 33 6 62 2.80 4.50
2zxeB01 78.23 1.20.5.170 35 8 45 0.75 1.66
1owaA01 77.59 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 0 60 2.81 4.65
3ii6A02 76.75 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 7 46 1.14 2.45
2v4hB00 76.70 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 9 52 2.09 3.96
1go9A00 76.60 1.20.5.480 39 7 52 2.03 3.84
1fdoA05 76.49 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 18 47 1.04 2.20
1kqfB03 76.11 Two-component systemMetabolic pathwaysGlyoxylate and dicarboxylate metabolismMethane metabolismFormate dehydrogenase activity 1.20.5.480 44 4 50 2.07 4.06
2gr7A00 76.04 Haemophilus influenzaeAdhesin 3.30.1300.30 101 3 43 1.09 2.50
1s3jB01 75.96 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 10 49 1.82 3.71
1h8bB00 75.90 TitinOryctolagus cuniculus 1.20.5.510 23 4 43 1.65 3.80
1aa0A00 75.59 Enterobacteria phage T4Fibritin 1.20.5.320 113 15 46 1.60 3.41
1ik7A00 75.50 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 1 45 1.40 3.09
1ozhA03 75.12 Acetolactate synthase, catabolicKlebsiella pneumoniae 1.20.5.740 24 8 45 1.66 3.67
1be3K00 73.82 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 9 41 1.16 2.79
2oarE02 73.45 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 13 41 1.36 3.28
1fxkC00 72.75 Methanothermobacter thermautotrophicus str. Delta HPrefoldin subunit alphaPrefoldin alpha subunit 1.10.287.370 133 5 36 1.06 2.94
2p1jB02 72.73 Thermotoga maritimaPyrimidine metabolismDNA replicationPurine metabolismMetabolic pathways 1.20.5.140 26 7 49 2.29 4.67
1htmD00 72.66 HemagglutininInfluenza A virus (A/Aichi/2/1968(H3N2)) 3.90.20.10 123 9 34 1.19 3.40
2pp6A01 71.31 Salmonella enterica subsp. enterica serovar TyphimuriumGifsy-2 prophage ATP-binding sugar transporter-like protein 1.20.5.110 21 9 39 1.80 4.54
1wa9B03 71.19 Regulation of circadian sleep/wake cycle, sleepPeriod circadian proteinNucleusResponse to temperature stimulusNegative regulation of transcription from RNA polymerase II promoter 1.20.5.770 33 0 37 1.15 3.05
3c8vA04 70.93 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 0 35 0.92 2.57
2qiwA02 68.62 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 22 33 0.91 2.68
2qfaA00 66.77 Baculoviral IAP repeat-containing protein 5Zinc ion bindingPositive regulation of mitotic cell cycleCaspase inhibitor activityMitosis 1.10.1170.10 134 3 28 1.30 4.58
1mslA02 66.51 1.20.5.220 18 5 33 1.36 4.00
2r05A03 65.95 Homo sapiensProgrammed cell death 6-interacting proteinCalcium-dependent protein binding 1.20.140.50 189 13 28 1.27 4.53
1d66B02 65.31 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 13 28 0.44 1.55
3g67A00 65.20 Thermotoga maritimaMethyl-accepting chemotaxis protein, putative 1.10.287.950 213 13 24 1.04 4.18
2oarA02 64.52 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 26 0.39 1.48
1mkmA02 61.71 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 0 26 0.72 2.73
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Displaying entries 1 to 91 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gl2A00
RVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gl2A00
GSHMSAGNDRVRNLQSEVEGVKNIMTQNVERILARGENLDHLRNKTEDLEATSEHFKTTSQKVAR
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"