CATH Domain: 1gk6A00 XML data for domain: 1gk6A00

Molscript image for 1gk6A00
1gk6A00
PDB coordinates for domain 1gk6A00

PDB 1gk6, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.2
1.20.5.170.2.1
1.20.5.170.2.1.1
1.20.5.170.2.1.1.1
1.20.5.170.2.1.1.1.2

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Segment boundaries for domain 1gk6A00

Chopping figure for domain 1gk6A00
DomainStart PDB ResidueStop PDB Residue
1gk6A00 355 409

Structural Neighbourhood (90 entries)

There are 90 matching structural neighberhood comparisons for CATH ID 1.20.5.170.2.1.1.1.2 (SIMAX score < 5)

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Displaying entries 1 to 90 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1jnmA00 91.88 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 56 11 89 0.81 0.91
1czqA00 91.75 1.20.5.170 45 6 86 0.78 0.90
1jekA00 90.76 Visna/maedi virus EV1 KV1772Envelope glycoprotein gp160 1.20.5.440 40 10 76 0.62 0.81
1ezjA02 89.53 Sendai virus (strain Harris)Phosphoprotein 1.10.287.340 52 13 84 2.41 2.85
2p7jB01 89.24 Vibrio parahaemolyticusPutative sensory box/GGDEF family protein 1.20.5.170 39 5 75 1.28 1.71
1r8eA03 88.87 Multidrug-efflux transporter 1 regulatorBacillus subtilis 1.20.5.490 44 9 80 1.18 1.46
1junA00 88.34 Pathways in cancerChagas diseaseNeurotrophin signaling pathwayB cell receptor signaling pathwayT cell receptor signaling pathway 1.20.5.170 43 4 82 1.32 1.60
1ik7A00 88.24 Regulation of proteolysisProtein domain specific bindingHemocyte proliferationPlasma membraneZygotic specification of dorsal/ventral axis 1.20.5.530 52 11 84 1.64 1.94
1l2pA00 87.06 Oxidative phosphorylationMetabolic pathwaysATP synthesis coupled proton transportAnchored to membraneF-type H+-transporting ATPase subunit b [EC:3.6.3.14] 1.20.5.620 61 5 83 2.36 2.82
2ifoA00 87.01 Xanthomonas phage XfCapsid protein G8P 1.20.5.230 46 4 88 1.71 1.93
3efgA00 86.83 Xanthomonas campestris pv. campestrisSlyX proteinProtein slyX homolog 1.20.5.300 49 10 71 1.14 1.60
1kilE00 86.83 Complexin-1Syntaxin-1 bindingRattus norvegicusDendriteSynaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex 1.20.5.580 41 9 78 2.16 2.74
1n2dC00 86.73 Mating projection tipGolgi inheritanceActin filament bindingVesicle-mediated transportMyosin-2 1.20.5.190 48 4 75 1.26 1.68
1ifpA00 86.63 Pseudomonas phage Pf3Capsid protein G8P 1.20.5.440 44 6 84 1.62 1.91
1gd2F00 86.61 NuA4 histone acetyltransferase complexFungal AP-1-like factorResponse to hydrogen peroxideResponse to methylglyoxalCellular response to oxidative stress 1.20.5.170 64 13 81 1.90 2.34
1nknA00 86.50 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Positive regulation of gene-specific transcription from RNA polymerase II promoter 1.20.5.340 74 15 70 1.03 1.47
3ii6A02 86.11 DNA ligation involved in DNA repairProtein C-terminus bindingDNA-dependent protein kinase-DNA ligase 4 complexResponse to X-rayDouble-strand break repair via nonhomologous end joining 1.20.5.370 58 7 89 3.06 3.41
1ci6A00 85.79 Positive regulation of transcription from RNA polymerase II promoterCellular amino acid metabolic processNeurotrophin signaling pathwayActivating transcription factor 4Sequence-specific DNA binding transcription factor activity 1.20.5.170 56 9 71 1.45 2.03
3effK02 85.48 Streptomyces lividansVoltage-gated potassium channel 1.20.5.440 45 4 76 1.24 1.61
1g2cB00 85.40 Human respiratory syncytial virus strain RSS-2Fusion glycoprotein F0 1.20.5.170 40 5 76 3.19 4.15
1lghB00 85.07 Phaeospirillum molischianumLight-harvesting protein B-800/850 beta 1 chain 1.20.5.250 43 9 73 3.36 4.60
3gwoA00 84.94 Human immunodeficiency virus type 1 lw12.3 isolateEnvelope glycoprotein gp160 1.10.287.210 53 1 67 1.65 2.43
1pl5A00 84.90 Chromatin silencing complexLoss of chromatin silencing involved in replicative cell agingChromatin silencingDouble-strand break repair via nonhomologous end joiningDouble-stranded DNA binding 1.20.5.730 75 15 68 1.03 1.51
2o1kA00 84.88 Simian rotavirus A/SA11-bothNon-structural glycoprotein 4 1.20.5.430 42 2 80 2.56 3.17
1gmjD00 84.82 Negative regulation of hydrolase activityProtein homodimerization activityATPase inhibitor activityBos taurusCalmodulin binding 1.20.5.500 56 13 76 2.21 2.88
3kpeA00 84.60 Fusion glycoprotein F0Human respiratory syncytial virus A2 1.20.5.300 47 10 63 1.57 2.47
1avyA00 84.57 Enterobacteria phage T4Fibritin 1.20.5.320 68 13 76 3.62 4.73
1piqA00 84.20 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyGeneral control protein GCN4General control protein GCN4Specific RNA polymerase II transcription factor activity 1.20.5.170 31 70 57 0.53 0.92
2zxeB01 84.10 1.20.5.170 35 5 67 1.91 2.84
1ltsC00 84.09 Heat-labile enterotoxin A chainEscherichia coli 1.20.5.240 41 0 78 3.89 4.93
1gk4C00 83.72 Cellular component movementProtein C-terminus bindingIntermediate filamentVimentinCytosol 1.20.5.170 70 13 70 2.10 3.00
1tiiC00 83.43 Heat-labile enterotoxin IIB, A chainEscherichia coli 1.20.5.200 36 2 69 2.35 3.39
2b9bA04 83.27 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.1070 62 15 67 2.82 4.16
1pfiA00 83.11 Pseudomonas phage Pf1Capsid protein G8P 1.20.5.230 46 6 76 2.27 2.95
1a2xB00 82.87 Troponin I, fast skeletal muscleTroponin T bindingOryctolagus cuniculus 1.20.5.420 31 12 59 1.10 1.85
1s5lX00 82.62 Photosystem II reaction center X proteinThermosynechococcus elongatus BP-1 1.20.5.510 40 7 71 2.58 3.63
2dw3A01 82.61 Intrinsic membrane protein pufXRhodobacter sphaeroides 2.4.1 1.20.5.920 55 7 80 3.18 3.98
1favA00 82.57 NucleusPositive regulation of RNA polymerase II transcriptional preinitiation complex assemblyEnvelope glycoprotein gp160General control protein GCN4General control protein GCN4 1.10.287.210 78 7 58 1.05 1.78
1dh3A00 82.50 Positive regulation of multicellular organism growthLactationRegulation of cell sizeAxonogenesisMus musculus 1.20.5.170 55 7 78 3.48 4.45
2zjsE00 82.23 Protein exportBacterial secretion systemThermus thermophilus HB8Preprotein translocase subunit secEPreprotein translocase subunit SecE 1.20.5.1030 46 6 76 3.18 4.13
1pp9E01 82.05 Cytochrome b-c1 complex subunit Rieske, mitochondrialBos taurus 1.20.5.270 64 9 59 1.29 2.17
1fjkA00 81.86 Calcium signaling pathwayDilated cardiomyopathySus scrofaCardiac phospholambanPhospholamban 1.20.5.290 52 5 75 3.02 4.03
1svfC00 81.73 Simian virus 5 (strain W3)Fusion glycoprotein F0 1.20.5.300 62 9 58 1.23 2.12
1e5wA04 81.69 Leukocyte migrationReceptor bindingCytoskeletonMembrane to membrane dockingNucleolus 1.20.5.450 55 5 69 3.36 4.86
1u57A00 81.60 Human immunodeficiency virus type 1 lw12.3 isolateGag polyprotein 1.20.5.760 48 8 75 2.64 3.52
2k1aA00 81.59 Integrin alpha 2BIdentical protein bindingPathways in cancerHematopoietic cell lineageDilated cardiomyopathy 1.20.5.930 42 0 75 3.49 4.65
1vf5C03 81.57 Mastigocladus laminosusApocytochrome f 1.20.5.700 32 9 61 1.65 2.68
2e42A00 81.46 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 13 60 2.60 4.33
1avyB00 81.34 Enterobacteria phage T4Fibritin 1.20.5.320 54 9 68 2.90 4.23
1xrdA01 81.26 Light-harvesting complex 1 alpha chainRhodospirillum rubrumLight-harvesting protein B-870 alpha chain 1.20.5.890 43 6 82 3.25 3.93
1gu4A00 81.10 Transcription from RNA polymerase II promoterAcute-phase responseHomo sapiensCCAAT/enhancer-binding protein betaImmune response 1.20.5.170 65 13 60 2.66 4.43
1owaA01 80.76 Structural constituent of cytoskeletonSpectrinHomo sapiensSpectrin-associated cytoskeletonActin filament organization 1.20.5.170 32 12 57 1.21 2.10
1omiA02 80.72 Listeria monocytogenesListeriolysin regulatory protein 1.20.5.460 27 7 51 0.72 1.39
2hr3A01 80.40 Probable transcriptional regulatorPseudomonas aeruginosa 1.20.5.420 30 6 57 2.06 3.57
2wpqA00 80.38 Salmonella enterica subsp. enterica serovar TyphimuriumPutative inner membrane protein 1.20.5.980 99 7 52 0.93 1.77
1wt6B00 80.29 ATP bindingProtein phosphorylationRegulation of heart contractionHomo sapiensProtein serine/threonine kinase activity 1.20.5.340 67 7 64 2.40 3.74
2v4hB00 80.27 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 91 13 57 1.23 2.15
1uixA00 80.25 Chemokine signaling pathwayRho-associated, coiled-coil containing protein kinase [EC:2.7.11.1]Leukocyte transendothelial migrationWnt signaling pathwayTGF-beta signaling pathway 1.20.5.730 68 11 66 2.69 4.06
1ybkA00 80.06 TetrabrachionStaphylothermus marinus 1.20.5.1060 52 5 59 2.11 3.54
1s3jB01 79.65 Bacillus subtilisUncharacterized HTH-type transcriptional regulator yusO 1.20.5.420 30 20 53 1.59 2.95
1d7mA00 79.56 Cortexillin-1Response to bacteriumProtein homodimerization activityActin filament bundle assemblyActin filament network formation 1.20.5.1050 101 13 46 0.70 1.50
1mg1A03 78.84 Bacterial chemotaxisABC transportersMaltose/maltodextrin transport system substrate-binding proteinEscherichia coli O157:H7Maltose-binding periplasmic protein 1.10.287.210 84 13 61 2.88 4.65
1ik9B02 78.60 DNA ligation involved in DNA repairResponse to X-rayDNA-dependent protein kinase-DNA ligase 4 complexProtein C-terminus bindingDouble-strand break repair via nonhomologous end joining 1.20.5.370 83 5 46 0.99 2.11
1ic2B00 78.20 Gallus gallusTropomyosin alpha-1 chain 1.20.5.340 77 5 50 1.64 3.24
1m7lA00 78.01 Negative regulation of T cell proliferationProtein bindingInnate immune responseLung alveolus developmentEndocytic vesicle 1.20.5.360 40 10 53 1.35 2.51
1hj0A00 77.98 Bos taurusThymosin beta-10 1.20.5.520 41 12 55 1.87 3.35
1fdoA05 77.78 Methane metabolismMetabolic pathwaysGlyoxylate and dicarboxylate metabolismFormate dehydrogenase HFormate dehydrogenase, alpha subunit [EC:1.2.1.2] 1.20.5.460 27 11 51 1.52 2.93
1kv4A00 77.31 Moricin-1Bombyx mori 1.20.5.750 42 4 55 2.58 4.63
2zvoB00 77.26 Mus musculusNF-kappa-B essential modulatorActivation of NF-kappaB-inducing kinase activityB cell homeostasis 1.20.5.990 88 9 46 0.79 1.70
2w83C00 76.97 Homo sapiensIntegral to membraneC-Jun-amino-terminal kinase-interacting protein 4SpermatogenesisPositive regulation of cell migration 1.20.5.1000 67 5 44 1.94 4.33
1jmmA01 76.62 Major cell-surface adhesin PAcStreptococcus mutans 1.20.5.250 32 18 51 1.39 2.68
2spcA00 76.50 Oocyte constructionSpectrosome organizationPlasma membrane organizationNegative regulation of microtubule depolymerizationGermarium-derived female germ-line cyst formation 1.20.58.60 107 9 48 1.86 3.83
2p10B02 76.30 Mesorhizobium lotiMll9387 protein 1.20.5.460 26 11 50 1.87 3.74
2r44A01 75.57 Cytophaga hutchinsonii ATCC 33406MoxR-like ATPase [EC:3.6.3.-]Putative uncharacterized protein 1.20.5.420 26 3 50 1.28 2.56
2oarE02 75.11 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 22 4 42 1.19 2.81
2dw4A03 74.82 Lysine-specific histone demethylase 1AHistone demethylase activityNucleusTranscription repressor activityHomo sapiens 1.10.287.80 101 5 41 1.73 4.16
1be3K00 74.39 Cardiac muscle contractionCytochrome b-c1 complex subunit 10Oxidative phosphorylationParkinson's diseaseAlzheimer's disease 1.20.5.220 22 22 42 1.17 2.77
1h8bB00 74.26 TitinOryctolagus cuniculus 1.20.5.510 23 8 38 0.64 1.66
2beqD00 72.81 Host cell surface receptor bindingSARS coronavirusSpike glycoproteinVirion attachment, binding of host cell surface receptor 1.20.5.790 46 8 75 3.50 4.67
1nafA01 72.61 ADP-ribosylation factor-binding protein GGA1Homo sapiensProtein bindingIntracellular protein transport 1.20.5.170 36 2 40 1.17 2.90
2oarA02 71.19 Large conductance mechanosensitive channel, MscL familyLarge-conductance mechanosensitive channelMycobacterium tuberculosis H37Ra 1.20.5.220 17 5 32 0.40 1.22
2b5uA02 70.73 Colicin-E3Escherichia coli 1.10.287.620 161 5 32 0.86 2.66
2qiwA02 69.92 Corynebacterium glutamicumPEP phosphonomutase and related enzymes 1.20.5.510 18 5 34 0.81 2.34
3c8vA04 69.71 Desulfovibrio desulfuricans subsp. desulfuricans str. G20Putative uncharacterized protein 1.20.5.510 19 5 36 1.11 3.04
1kmiZ02 69.27 Bacterial chemotaxisChemotaxis protein cheZProtein bindingChemotaxis protein CheZEscherichia coli K-12 1.10.287.500 134 13 38 1.64 4.31
1fxkC00 68.79 Methanothermobacter thermautotrophicus str. Delta HPrefoldin subunit alphaPrefoldin alpha subunit 1.10.287.370 133 11 32 1.48 4.58
1mslA02 68.30 1.20.5.220 18 11 34 1.19 3.44
1d66B02 66.91 Regulatory protein GAL4NucleusSequence-specific DNA binding transcription factor activityTranscription activator activityPositive regulation of transcription by galactose 1.20.5.640 15 0 28 0.32 1.11
3g67A00 66.50 Thermotoga maritimaMethyl-accepting chemotaxis protein, putative 1.10.287.950 213 7 24 0.76 3.11
1mkmA02 62.90 Thermotoga maritimaTranscriptional regulator, IclR family 1.20.5.640 14 21 26 0.57 2.12
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Displaying entries 1 to 90 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gk6A00
MKQLEDKVEELLSKNYHLENEVARLKKLVGDLLNVKMALDIEIATYRKLLEGEES
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gk6A00
RMKQLEDKVEELLSKNYHLENEVARLKKLVGDLLNVKMALDIEIATYRKLLEGEESRIS
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:17

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:39

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"