CATH Domain: 1gcqC00 XML data for domain: 1gcqC00

Molscript image for 1gcqC00
1gcqC00
PDB coordinates for domain 1gcqC00

PDB 1gcq, Chain C, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.20
2.30.30.40.20.1
2.30.30.40.20.1.1
2.30.30.40.20.1.1.1
2.30.30.40.20.1.1.1.1

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Segment boundaries for domain 1gcqC00

Chopping figure for domain 1gcqC00
DomainStart PDB ResidueStop PDB Residue
1gcqC00 591 659

Structural Neighbourhood (45 entries)

There are 45 matching structural neighberhood comparisons for CATH ID 2.30.30.40.20.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 45 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ad5A01 89.24 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 22 85 1.67 1.95
2v1rA00 88.96 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 14 89 2.52 2.80
2vwfA00 88.29 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 21 81 1.82 2.24
2jteA00 87.98 Mus musculusCD2-associated protein 2.30.30.40 64 21 88 3.09 3.50
1x6bA01 87.88 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 20 85 1.97 2.30
2rqtA00 87.77 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 19 85 2.44 2.85
1spkA00 87.60 Mus musculusBrain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 2.30.30.40 72 21 88 3.19 3.59
1wx6A01 87.56 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 19 88 2.88 3.26
2j6fA00 87.26 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 26 82 2.38 2.88
1uhfA00 87.09 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 69 20 85 2.93 3.43
2vknA00 86.99 MAPK signaling pathway - yeastIdentical protein bindingMating projection tipPseudohyphal growthOsmosensor activity 2.30.30.40 66 18 89 2.89 3.22
1awwA00 86.78 Phosphatidylinositol-3,4,5-trisphosphate bindingInduction of apoptosis by extracellular signalsIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.30.40 67 20 88 2.67 3.02
1yn8A00 86.76 NucleusHyperosmotic responseResponse to heatNegative regulation of protein kinase activityProtein binding 2.30.30.40 59 20 85 2.64 3.09
2ablA01 86.75 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 66 13 88 3.39 3.83
2js2A00 86.67 Receptor bindingNCK adaptor proteinPositive regulation of T cell proliferationT cell receptor signaling pathwayPositive regulation of actin filament polymerization 2.30.30.40 63 19 86 3.52 4.05
1ycsB02 86.66 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 20 86 3.12 3.59
2csqA01 86.57 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 20 91 2.83 3.10
3ehrB01 86.39 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 19 84 2.42 2.88
1jegA00 86.36 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 18 86 2.49 2.86
3i5rA00 86.31 ErbB-3 class receptor bindingInsulin-like growth factor receptor signaling pathwayInsulin receptor signaling pathwayGrowth hormone receptor signaling pathwayInsulin-like growth factor receptor binding 2.30.30.40 81 21 77 2.39 3.07
1ov3A02 86.24 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 20 78 1.95 2.49
1j3tA00 86.07 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 74 20 79 2.38 2.99
2ke9A00 85.54 Caskin-2Homo sapiens 2.30.30.40 67 14 88 2.97 3.36
1bb9A00 84.53 Rattus norvegicusProtein heterodimerization activityProtein C-terminus bindingSynaptic vesicle endocytosisMyc box-dependent-interacting protein 1 2.30.30.40 83 20 75 3.53 4.65
1griA01 84.24 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 18 69 1.75 2.52
2epdA00 83.39 Rho protein signal transductionCytoskeleton organizationRho GTPase-activating protein 4Homo sapiensRho GTPase activator activity 2.30.30.40 76 17 78 2.82 3.57
1ng2A01 82.52 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 22 63 2.09 3.28
1jxmA01 82.27 Postsynaptic membraneRattus norvegicusProtein C-terminus bindingIonotropic glutamate receptor bindingDisks large homolog 4 2.30.30.40 80 15 67 2.81 4.16
1sf9A02 81.38 Bacillus subtilisUncharacterized protein yfhH 2.30.30.340 54 11 69 3.29 4.73
1u3oA01 81.27 Rattus norvegicusVesicle-mediated transportProtein bindingAxonogenesisNeuron projection 2.30.30.40 62 20 85 2.96 3.46
1tucA00 81.11 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 61 14 65 3.03 4.65
2heqA01 80.49 Bacillus subtilisSPBc2 prophage-derived uncharacterized protein yorP 2.30.30.40 54 9 76 3.14 4.09
1i1jB00 80.47 Melanoma-derived growth regulatory proteinHomo sapiensExtracellular spaceCell proliferation 2.30.30.40 103 17 61 2.57 4.20
1mhnA00 80.29 Survival motor neuron proteinSurvival motor neuron proteinHomo sapiensProtein binding 2.30.30.140 59 3 78 3.76 4.80
1udlA00 80.26 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 98 15 61 2.23 3.64
2o2oA00 80.03 NucleusHomo sapiensSH3 domain-containing kinase-binding protein 1 2.30.30.40 75 23 80 3.51 4.39
1ug1A00 79.97 Dynamin-binding proteinHomo sapiensProtein binding 2.30.30.40 92 15 66 2.64 3.98
1igqB00 79.30 Escherichia coliTranscriptional repressor protein korB 2.30.30.150 57 5 69 3.40 4.89
1uffA00 79.29 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 93 23 65 3.23 4.92
1jb0E00 79.17 Photosystem I subunit IVPhotosynthesisThermosynechococcus elongatus BP-1Photosystem I reaction center subunit IVMetabolic pathways 2.30.30.50 69 7 79 3.94 4.94
2rh2A00 78.95 Dihydrofolate reductase type 2Escherichia coli 2.30.30.60 57 7 71 3.27 4.60
1vytA01 76.44 Cardiac muscle contractionRattus norvegicusDilated cardiomyopathyVoltage-gated calcium channel complexCalcium channel, voltage-dependent, beta 3 subunit 2.30.30.40 108 13 62 2.57 4.08
1awjA00 75.42 Mus musculusTyrosine-protein kinase ITK/TSKProtein binding 2.30.30.40 77 14 76 3.54 4.62
1u1sA00 75.01 RNA degradationPseudomonas aeruginosaHost factor-I proteinProtein hfq 2.30.30.100 66 4 63 3.09 4.85
1irxA02 74.80 Aminoacyl-tRNA biosynthesisLysyl-tRNA synthetase, class I [EC:6.1.1.6]Pyrococcus horikoshiiLysyl-tRNA synthetase 2.30.30.300 43 6 60 2.73 4.49
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Displaying entries 1 to 45 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1gcqC00
GSHMPKMEVFQEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1gcqC00
GSHMPKMEVFQEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVH
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"