CATH Domain: 1g2bA00 XML data for domain: 1g2bA00

Molscript image for 1g2bA00
1g2bA00
PDB coordinates for domain 1g2bA00

PDB 1g2b, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.3
2.30.30.40.3.1
2.30.30.40.3.1.1
2.30.30.40.3.1.1.1
2.30.30.40.3.1.1.1.1

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Segment boundaries for domain 1g2bA00

Chopping figure for domain 1g2bA00
DomainStart PDB ResidueStop PDB Residue
1g2bA00 0 47

Structural Neighbourhood (35 entries)

There are 35 matching structural neighberhood comparisons for CATH ID 2.30.30.40.3.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 35 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3i9qA00 89.08 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 57 63 66 0.47 0.71
2v1qA00 87.80 Actin cortical patch assemblyMating projection tipIdentical protein bindingNucleusActin filament organization 2.30.30.40 60 25 66 0.73 1.09
2vwfA00 85.88 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 56 17 64 0.68 1.06
1zlmA00 85.44 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 58 18 69 2.14 3.08
1ng2A01 85.33 Soluble fractionGTP bindingCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 44 20 67 1.12 1.65
1ckaA00 85.01 Pathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayFc gamma R-mediated phagocytosisErbB signaling pathway 2.30.30.40 56 23 66 1.17 1.77
1ov3A01 84.92 GTP bindingSoluble fractionCellular defense responseSH3 domain bindingSuperoxide anion generation 2.30.30.40 55 16 64 1.13 1.75
1sshA00 83.94 Cellular bud neckIdentical protein bindingActin cortical patch localizationSaccharomyces cerevisiaeMitochondrion 2.30.30.40 60 18 68 2.86 4.19
1ov3A02 83.92 GTP bindingSoluble fractionSH3 domain bindingCellular defense responseSuperoxide anion generation 2.30.30.40 54 14 64 1.03 1.60
1yn8A00 83.74 NucleusHyperosmotic responseResponse to heatNegative regulation of protein kinase activityProtein binding 2.30.30.40 59 15 66 1.31 1.98
1w70A00 83.40 Protein dimerization activityLeukocyte transendothelial migrationNeutrophil cytosolic factor 4CytosolNADPH oxidase complex 2.30.30.40 60 23 70 3.06 4.37
3i35A00 83.22 Focal adhesionHomo sapiensLIM and SH3 domain protein 1SH3/SH2 adaptor activity 2.30.30.40 56 16 64 1.17 1.82
1ad5A01 83.09 Protein phosphorylationTyrosine-protein kinase HCKHomo sapiensMesoderm developmentProtein binding 2.30.30.40 63 22 61 0.90 1.45
2j6fA00 82.90 CD2-associated proteinRufflePlasma membraneSH3 domain bindingStructural constituent of cytoskeleton 2.30.30.40 57 14 64 1.43 2.22
1y0mA00 82.75 Rattus norvegicusCalcium signaling pathwayPhosphatidylinositol signaling systemPathways in cancerPhospholipase C, gamma [EC:3.1.4.11] 2.30.30.40 60 22 68 1.44 2.11
2ak5B00 82.68 Rattus norvegicusFocal adhesionProtein bindingGrowth coneCytoplasm 2.30.30.40 64 16 68 2.55 3.71
3eg3A00 82.67 DNA damage response, signal transduction resulting in induction of apoptosisProto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2]Pathways in cancerNucleolusNeurotrophin signaling pathway 2.30.30.40 62 16 67 2.50 3.69
2v1rA00 82.61 PeroxisomePeroxin-13Protein binding, bridgingPeroxisomal membrane protein PAS20Peroxisomal membrane 2.30.30.40 67 28 64 2.66 4.14
1zuyA00 82.60 Identical protein bindingMating projection tipReceptor-mediated endocytosisActin cortical patch localizationResponse to salt stress 2.30.30.40 58 18 64 1.34 2.08
1jegA00 82.44 Tyrosine-protein kinase CSKProtein bindingCell-cell junctionMus musculusATP binding 2.30.30.40 60 16 66 1.70 2.55
1jo8A00 82.40 Actin cortical patch assemblyMating projection tipActin-binding proteinEstablishment of cell polarityProtein localization 2.30.30.40 58 17 64 1.15 1.79
3h0hA00 82.39 T cell receptor signaling pathwayLearningPrion diseasesFeeding behaviorTyrosine-protein kinase Fyn 2.30.30.40 63 28 68 2.48 3.63
1x6bA01 82.07 Rho guanine nucleotide exchange factor 16Homo sapiens 2.30.30.40 64 13 60 1.05 1.72
1ycsB02 81.67 Induction of apoptosisNF-kappaB bindingNegative regulation of cell cycleHomo sapiensApoptosis-stimulating of p53 protein 2 2.30.30.40 64 22 68 1.95 2.84
3ehrB01 81.64 Osteoclast-stimulating factor 1OssificationIdentical protein bindingHomo sapiensSignal transduction 2.30.30.40 62 18 64 2.44 3.78
1wyxA00 81.63 RuffleMembrane fractionIntegrin-mediated signaling pathwayB cell receptor signaling pathwayActin filament organization 2.30.30.40 68 27 58 1.27 2.16
1griA01 81.49 Jak-STAT signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancerT cell receptor signaling pathwayErbB signaling pathway 2.30.30.40 48 22 55 0.81 1.45
2rqtA00 80.55 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing proteinArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Fc gamma R-mediated phagocytosisHomo sapiensProtein binding 2.30.30.40 61 15 63 1.47 2.30
2csqA01 80.03 RIMS-binding protein 2Homo sapiens 2.30.30.40 65 13 60 1.82 3.03
1gcqC00 79.71 Integrin-mediated signaling pathwayProto-oncogene vavProtein bindingMus musculusT cell differentiation 2.30.30.40 69 15 60 2.77 4.55
1wx6A01 79.34 NCK adaptor proteinPositive regulation of T cell proliferationRegulation of epidermal growth factor receptor activityT cell receptor signaling pathwayEpidermal growth factor receptor signaling pathway 2.30.30.40 66 15 62 2.42 3.90
1tucA00 78.86 Spectrin alpha chain, brainGallus gallusSpectrin alpha 2.30.30.40 61 52 52 1.44 2.75
2ke9A00 76.36 Caskin-2Homo sapiens 2.30.30.40 67 20 59 2.21 3.70
2fj8A01 72.03 Bowman-Birk type trypsin inhibitorHordeum vulgare 2.10.69.10 60 3 80 3.62 4.53
1uffA00 71.88 Intersectin-2Homo sapiensSH3/SH2 adaptor activity 2.30.30.40 93 15 46 2.28 4.93
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Displaying entries 1 to 35 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1g2bA00
MDRQGFVPAAYVKKLDSGTGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1g2bA00
MDRQGFVPAAYVKKLDSGTGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"