CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Protein-glutamine gamma-glutamyltransferase 2

Enzyme Information

2.3.2.13
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt P52181
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)- (gamma-glutamyl)-L-lysine cross-link + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine cross-links.

UniProtKB Entries (1)

P52181
TGM2_PAGMA
Pagrus major
Protein-glutamine gamma-glutamyltransferase 2

PDB Structure

PDB 1G0D
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of red sea bream transglutaminase.
Noguchi, K., Ishikawa, K., Yokoyama, K.i., Ohtsuka, T., Nio, N., Suzuki, E.
J.Biol.Chem.