CATH Domain: 1faoA00 XML data for domain: 1faoA00

Molscript image for 1faoA00
1faoA00
PDB coordinates for domain 1faoA00

PDB 1fao, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.29 PH-domain like
2.30.29.30 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) Gene3D
2.30.29.30.17
2.30.29.30.17.1
2.30.29.30.17.1.1
2.30.29.30.17.1.1.1
2.30.29.30.17.1.1.1.1

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Segment boundaries for domain 1faoA00

Chopping figure for domain 1faoA00
DomainStart PDB ResidueStop PDB Residue
1faoA00 162 261

Structural Neighbourhood (30 entries)

There are 30 matching structural neighberhood comparisons for CATH ID 2.30.29.30.17.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 30 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
3cxbB00 90.99 Kinesin bindingPleckstrin homology domain-containing family M member 2Golgi organizationHomo sapiens 2.30.29.30 102 23 94 1.41 1.50
1qqgA01 89.72 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 103 21 88 1.72 1.95
1btnA00 87.82 Mus musculusSpectrin beta chain, brain 1SMAD protein import into nucleusCuticular platePlasma membrane 2.30.29.30 106 17 84 1.54 1.81
1omwA05 87.48 MembraneNegative regulation of the force of heart contraction by chemical signalG-protein coupled receptor kinase activityChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 2.30.29.30 101 23 91 2.20 2.42
2dn6A00 87.30 CytoplasmPlasma membraneSwitch-associated protein 70Homo sapiens 2.30.29.30 115 24 86 2.38 2.74
1v89A00 86.99 Homo sapiensRho GTPase-activating protein 25 2.30.29.30 118 28 83 2.91 3.47
1qqgA02 86.62 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 104 10 88 2.50 2.83
1dynA00 85.68 GTPase activityReceptor-mediated endocytosisHomo sapiensDynamin-1Protein binding 2.30.29.30 113 21 86 2.95 3.40
2he7A03 85.67 Tight junctionErythrocyte membrane protein band 4.1Homo sapiensBand 4.1-like protein 3Cell-cell junction 2.30.29.30 95 9 85 2.23 2.62
1t77A01 85.26 Lipopolysaccharide-responsive and beige-like anchor proteinHomo sapiensProtein binding 2.30.29.40 105 7 85 3.96 4.62
1ef1A03 84.97 Receptor bindingLeukocyte migrationCytoskeletonMembrane to membrane dockingNucleolus 2.30.29.30 95 9 87 2.41 2.77
2dhjA00 84.16 Rho GTPase-activating protein 21Homo sapiens 2.30.29.30 125 19 79 2.20 2.78
1plsA00 83.92 Soluble fractionInhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathwayHemopoietic progenitor cell differentiationActin cytoskeleton reorganizationRegulation of cell diameter 2.30.29.30 113 21 88 2.84 3.21
2coaA01 83.49 Homo sapiensSerine/threonine-protein kinase D2 2.30.29.30 118 16 82 2.22 2.70
2rgnB02 83.16 Homo sapiensGuanine nucleotide exchange factor GEFT 2.30.29.30 123 10 77 2.49 3.22
1mixA02 83.06 Talin-1Focal adhesionFocal adhesionGallus gallusTalin 2.30.29.30 93 11 89 3.27 3.67
1p5tA00 82.86 Mus musculusRas protein signal transductionDocking protein 1Transmembrane receptor protein tyrosine kinase signaling pathwayTransmembrane receptor protein tyrosine kinase signaling protein activity 2.30.29.30 105 11 82 2.74 3.31
1dbhA02 82.77 Jak-STAT signaling pathwayPathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancer 2.30.29.30 124 16 72 3.23 4.45
1v88A00 82.45 Oxysterol-binding protein-related protein 8Homo sapiens 2.30.29.30 130 20 73 2.40 3.25
1kz7C02 82.42 Mus musculusGuanine nucleotide exchange factor DBSRho guanyl-nucleotide exchange factor activityRho protein signal transductionLamellipodium 2.30.29.30 134 14 71 3.04 4.24
1xr0B01 82.02 Fibroblast growth factor receptor substrate 2Membrane fractionIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase adaptor activityNeurotrophin signaling pathway 2.30.29.30 91 10 84 2.78 3.31
1btkA00 81.88 Induction of apoptosis by extracellular signalsPhosphatidylinositol-3,4,5-trisphosphate bindingIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.29.30 160 16 61 2.14 3.46
1aqcB00 81.38 Nervous system developmentSynaptic transmissionCell adhesionAmyloid beta (A4) precursor protein-binding, family A, member 1 (X11)Axon cargo transport 2.30.29.30 114 9 72 2.81 3.86
1pfjA00 81.19 Positive regulation of transcription from RNA polymerase II promoterGeneral RNA polymerase II transcription factor activityGeneral transcription factor IIH subunit 1Nucleotide excision repairRegulation of cyclin-dependent protein kinase activity 2.30.29.30 108 8 86 3.53 4.10
1rrpB00 80.35 E3 SUMO-protein ligase RanBP2Ran GTPase bindingNuclear poreProtein import into nucleusHomo sapiens 2.30.29.30 134 11 71 3.25 4.54
1fhoA00 79.18 Caenorhabditis elegansMuscle M-line assembly protein unc-89Locomotion 2.30.29.30 119 13 80 3.91 4.85
1ki1B02 78.71 Synaptic vesicle endocytosisHomo sapiensProtein bindingIntersectin-1 2.30.29.30 142 17 62 2.70 4.31
1q67A01 78.57 MRNA-decapping enzyme subunit 1Cytoplasmic mRNA processing bodyRNA degradationEnzyme activator activityMRNA binding 2.30.29.30 140 8 65 3.11 4.78
1ntvA00 77.74 Radial glia guided migration of Purkinje cellDisabled homolog 1Cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migrationNegative regulation of cell adhesionMus musculus 2.30.29.30 152 15 62 3.07 4.91
1ddmA00 75.58 Notch signaling pathwaySensory organ precursor cell fate determinationSensory organ precursor cell divisionProtein localizationDrosophila melanogaster 2.30.29.30 135 10 71 3.04 4.23
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Displaying entries 1 to 30 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1faoA00
PSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNCFCLVFPFRTFYLCA
KTGVEADEWIKILRWKLSQI
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1faoA00
MQTGRTEDDLVPTAPSLGTKEGYLTKQGGLVKTWKTRWFTLHRNELKYFKDQMSPEPIRILDLTECSAVQFDYSQERVNC
FCLVFPFRTFYLCAKTGVEADEWIKILRWKLSQIRKQLNQGEGTIR
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"