CATH Domain: 1evhA00 XML data for domain: 1evhA00

Molscript image for 1evhA00
1evhA00
PDB coordinates for domain 1evhA00

PDB 1evh, Chain A, Domain 0

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.29 PH-domain like
2.30.29.30 Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) Gene3D
2.30.29.30.13
2.30.29.30.13.1
2.30.29.30.13.1.1
2.30.29.30.13.1.1.1
2.30.29.30.13.1.1.1.1

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Segment boundaries for domain 1evhA00

Chopping figure for domain 1evhA00
DomainStart PDB ResidueStop PDB Residue
1evhA00 2 112

Structural Neighbourhood (30 entries)

There are 30 matching structural neighberhood comparisons for CATH ID 2.30.29.30.13.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 30 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1rrpB00 85.95 E3 SUMO-protein ligase RanBP2Ran GTPase bindingNuclear poreProtein import into nucleusHomo sapiens 2.30.29.30 134 19 78 1.66 2.12
1qqgA01 83.60 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 103 4 82 2.92 3.52
1faoA00 83.22 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidePhosphatidylinositol-3,4,5-trisphosphate bindingDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidePlasma membraneB cell receptor signaling pathway 2.30.29.30 100 5 85 3.21 3.75
1zsqA01 82.92 [EC:3.1.3.-]NucleusFructose and mannose metabolismMetabolic pathwaysRiboflavin metabolism 2.30.29.30 101 3 80 2.56 3.19
1mkeA00 82.58 Rattus norvegicusNeural Wiskott-Aldrich syndrome protein 2.30.29.30 144 16 73 1.98 2.69
3cxbB00 82.37 Kinesin bindingPleckstrin homology domain-containing family M member 2Golgi organizationHomo sapiens 2.30.29.30 102 7 85 3.07 3.59
2dn6A00 82.30 CytoplasmPlasma membraneSwitch-associated protein 70Homo sapiens 2.30.29.30 115 5 83 2.89 3.46
1t77A01 82.01 Lipopolysaccharide-responsive and beige-like anchor proteinHomo sapiensProtein binding 2.30.29.40 105 4 75 2.59 3.42
1omwA05 81.94 MembraneNegative regulation of the force of heart contraction by chemical signalG-protein coupled receptor kinase activityChemokine signaling pathwayMuscarinic acetylcholine receptor signaling pathway 2.30.29.30 101 6 81 2.74 3.38
1v89A00 81.71 Homo sapiensRho GTPase-activating protein 25 2.30.29.30 118 7 80 2.82 3.50
1q67A01 81.49 MRNA-decapping enzyme subunit 1Cytoplasmic mRNA processing bodyRNA degradationEnzyme activator activityMRNA binding 2.30.29.30 140 11 74 2.39 3.22
1dynA00 81.13 GTPase activityReceptor-mediated endocytosisHomo sapiensDynamin-1Protein binding 2.30.29.30 113 7 83 3.37 4.05
2rgnB02 80.92 Homo sapiensGuanine nucleotide exchange factor GEFT 2.30.29.30 123 9 74 2.74 3.66
1p5tA00 80.51 Mus musculusRas protein signal transductionDocking protein 1Transmembrane receptor protein tyrosine kinase signaling pathwayTransmembrane receptor protein tyrosine kinase signaling protein activity 2.30.29.30 105 8 81 2.92 3.60
1pfjA00 80.44 Positive regulation of transcription from RNA polymerase II promoterGeneral RNA polymerase II transcription factor activityGeneral transcription factor IIH subunit 1Nucleotide excision repairRegulation of cyclin-dependent protein kinase activity 2.30.29.30 108 7 81 2.83 3.49
1w1hD00 80.41 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]PPAR signaling pathwayPeptidyl-threonine phosphorylationAldosterone-regulated sodium reabsorptionNon-small cell lung cancer 2.30.29.30 137 4 68 2.56 3.73
1plsA00 80.19 Soluble fractionInhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathwayHemopoietic progenitor cell differentiationActin cytoskeleton reorganizationRegulation of cell diameter 2.30.29.30 113 8 84 3.56 4.23
1btnA00 80.14 Mus musculusSpectrin beta chain, brain 1SMAD protein import into nucleusCuticular platePlasma membrane 2.30.29.30 106 9 81 3.39 4.18
1ef1A03 80.13 Receptor bindingLeukocyte migrationCytoskeletonMembrane to membrane dockingNucleolus 2.30.29.30 95 3 77 2.89 3.73
2dhjA00 80.12 Rho GTPase-activating protein 21Homo sapiens 2.30.29.30 125 3 79 3.42 4.32
1txdA02 80.07 Rho guanine nucleotide exchange factor 12Homo sapiensRegulation of actin cytoskeletonG-protein-coupled receptor bindingG-protein coupled receptor protein signaling pathway 2.30.29.30 121 10 78 2.73 3.48
1kz7C02 80.05 Mus musculusGuanine nucleotide exchange factor DBSRho guanyl-nucleotide exchange factor activityRho protein signal transductionLamellipodium 2.30.29.30 134 9 71 3.21 4.48
1dbhA02 79.70 Jak-STAT signaling pathwayPathways in cancerChemokine signaling pathwayNeurotrophin signaling pathwayNon-small cell lung cancer 2.30.29.30 124 4 70 2.70 3.85
1ddmA00 79.05 Notch signaling pathwaySensory organ precursor cell fate determinationSensory organ precursor cell divisionProtein localizationDrosophila melanogaster 2.30.29.30 135 7 74 3.40 4.59
2he7A03 78.68 Tight junctionErythrocyte membrane protein band 4.1Homo sapiensBand 4.1-like protein 3Cell-cell junction 2.30.29.30 95 3 75 2.84 3.75
2coaA01 78.57 Homo sapiensSerine/threonine-protein kinase D2 2.30.29.30 118 9 78 3.07 3.90
1qqgA02 78.22 Phosphoinositide 3-kinase bindingAldosterone-regulated sodium reabsorptionNeurotrophin signaling pathwayNegative regulation of insulin secretionInsulin-like growth factor receptor signaling pathway 2.30.29.30 104 6 86 3.88 4.49
1btkA00 76.88 Induction of apoptosis by extracellular signalsPhosphatidylinositol-3,4,5-trisphosphate bindingIdentical protein bindingPlasma membraneB cell receptor signaling pathway 2.30.29.30 160 4 62 2.77 4.43
1ki1B02 76.74 Synaptic vesicle endocytosisHomo sapiensProtein bindingIntersectin-1 2.30.29.30 142 7 64 3.02 4.71
1xr0B01 75.11 Fibroblast growth factor receptor substrate 2Membrane fractionIntegral to plasma membraneTransmembrane receptor protein tyrosine kinase adaptor activityNeurotrophin signaling pathway 2.30.29.30 91 4 73 3.09 4.18
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Displaying entries 1 to 30 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1evhA00
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWR
DARQVYGLNFGSKEDANVFASAMMHALEVLN
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1evhA00
MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQW
RDARQVYGLNFGSKEDANVFASAMMHALEVLN
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:24

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 14:47

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"