CATH Domain: 1eerC01 XML data for domain: 1eerC01

Molscript image for 1eerC01
1eerC01
PDB coordinates for domain 1eerC01

PDB 1eer, Chain C, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.89
2.60.40.10.89.1
2.60.40.10.89.1.1
2.60.40.10.89.1.1.1
2.60.40.10.89.1.1.1.1

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Segment boundaries for domain 1eerC01

Chopping figure for domain 1eerC01
DomainStart PDB ResidueStop PDB Residue
1eerC01 22 118
1eerC02 119 220

Structural Neighbourhood (55 entries)

There are 55 matching structural neighberhood comparisons for CATH ID 2.60.40.10.89.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 55 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1iarB01 85.62 Jak-STAT signaling pathwayInterleukin 4 receptorIntegral to plasma membraneInterleukin-4 receptor activityHematopoietic cell lineage 2.60.40.10 96 15 93 2.80 2.98
1axiB01 84.58 Jak-STAT signaling pathwayMulticellular organismal metabolic processCell surfaceGrowth hormone receptor complexInsulin-like growth factor receptor signaling pathway 2.60.40.10 86 19 85 3.73 4.36
1f6fB01 84.55 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 17 91 3.93 4.28
1bquA01 82.57 Oncostatin-M receptor complexJak-STAT signaling pathwayResponse to cytokine stimulusPositive regulation of tyrosine phosphorylation of Stat1 proteinPositive regulation of osteoblast differentiation 2.60.40.10 100 14 89 3.31 3.72
1fyhB01 82.12 Jak-STAT signaling pathwayInterferon gamma receptor 1Integral to plasma membraneChagas diseaseInterferon-gamma receptor activity 2.60.40.10 97 10 89 3.49 3.89
2qfpA01 81.60 Fe(3+)-Zn(2+) purple acid phosphatasePhaseolus vulgaris 2.60.40.380 97 6 89 3.78 4.21
1n26A01 81.39 Positive regulation of chemokine productionJak-STAT signaling pathwayPositive regulation of smooth muscle cell proliferationResponse to cytokine stimulusAcute-phase response 2.60.40.10 107 10 83 3.61 4.34
1fnfA02 81.24 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 87 8 84 2.93 3.47
1g0dA04 81.14 Protein-glutamine gamma-glutamyltransferase 2Pagrus major 2.60.40.10 97 8 89 3.87 4.31
2gysA03 81.04 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaApoptosis 2.60.40.10 86 17 83 3.95 4.73
1tdqA02 80.99 Nervous system developmentRattus norvegicusTenascinFocal adhesionProteinaceous extracellular matrix 2.60.40.10 90 10 87 3.41 3.89
1fnhA03 80.93 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 11 86 3.86 4.46
1cd9D01 80.67 Mus musculusGranulocyte colony-stimulating factor receptorNeutrophil chemotaxis 2.60.40.10 107 15 83 3.38 4.06
1vjjA04 80.42 Calcium ion bindingHair follicle morphogenesisGTP bindingExtrinsic to internal side of plasma membraneTransglutaminase 3 [EC:2.3.2.13] 2.60.40.10 97 7 87 4.11 4.69
1fnfA03 80.41 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 89 10 84 3.50 4.14
1f6fB02 80.37 Rattus norvegicusProlactin receptorProlactin receptor activity 2.60.40.10 97 9 86 4.17 4.82
1qg3A02 80.34 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 104 15 85 4.11 4.80
2e7hA01 80.32 Cell surfaceOrgan morphogenesisIntegral to plasma membraneEph receptor B4 [EC:2.7.10.1]Homo sapiens 2.60.40.10 89 10 83 3.26 3.90
1j8kA00 80.13 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 94 9 89 3.95 4.40
1qg3A01 79.99 Homo sapiensIntegrin beta-4Protein bindingIntegrin complex 2.60.40.10 91 10 83 3.72 4.45
1qr4A01 79.96 TenascinGallus gallus 2.60.40.10 87 9 85 3.50 4.09
2gysA02 79.93 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 102 10 81 3.90 4.79
3di2B02 79.87 Interleukin-7 receptor activityRegulation of DNA recombinationInterleukin-7 receptor subunit alphaHomo sapiensCell surface receptor linked signaling pathway 2.60.40.10 103 13 85 3.98 4.66
2cumA00 79.87 Collagen metabolic processElastic fiber assemblyIntracellularHomo sapiensTenascin-X 2.60.40.10 105 11 80 3.83 4.73
3h9yB01 79.86 Homo sapiensIg epsilon chain C region 2.60.40.10 101 10 89 3.55 3.98
3fruA02 79.68 IgG receptor FcRn large subunit p51Beta-2-microglobulin bindingRattus norvegicusHumoral immune responseIgG receptor activity 2.60.40.10 92 10 88 4.18 4.71
1cidA02 79.40 Rattus norvegicusT-cell surface glycoprotein CD4Hematopoietic cell lineageT cell receptor signaling pathwayAntigen processing and presentation 2.60.40.10 71 7 73 2.62 3.58
1fnhA01 79.38 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 14 86 3.76 4.34
2gysB04 79.35 Jak-STAT signaling pathwayCytokine receptor common subunit betaApoptosisCytokine-cytokine receptor interactionGranulocyte macrophage colony-stimulating factor receptor complex 2.60.40.10 99 12 80 3.78 4.68
1cwvA02 79.29 InvasinYersinia pseudotuberculosis 2.60.40.920 97 10 82 3.64 4.41
1ut9A01 78.93 Clostridium thermocellumCellobiohydrolase 2.60.40.10 98 4 91 3.89 4.24
1o0vA01 78.74 Homo sapiensIg epsilon chain C region 2.60.40.10 102 6 85 3.79 4.44
1ow0A01 78.71 Homo sapiensProtein bindingIg alpha-1 chain C region 2.60.40.10 100 10 89 3.82 4.29
2bc4A02 78.68 HLA class II histocompatibility antigen, DM alpha chainHomo sapiensProtein binding 2.60.40.10 109 12 81 3.84 4.70
1jz7A04 78.51 Galactose metabolismSphingolipid metabolismOther glycan degradationMetabolic pathwaysLactose catabolic process 2.60.40.320 106 10 79 3.86 4.87
1axiB02 78.46 Jak-STAT signaling pathwayCell surfaceMulticellular organismal metabolic processGrowth hormone receptor complexInsulin-like growth factor receptor signaling pathway 2.60.40.10 101 15 82 3.96 4.82
1y6kR02 78.14 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 103 7 78 3.77 4.79
2gysA01 78.08 Jak-STAT signaling pathwayGranulocyte macrophage colony-stimulating factor receptor complexCytokine receptor common subunit betaCytokine receptor common subunit betaCytokine-cytokine receptor interaction 2.60.40.10 95 8 84 4.03 4.77
1o75A04 78.05 Treponema pallidum47 kDa membrane antigen 2.60.40.1270 82 8 77 3.86 4.99
1y6kR01 77.94 Interleukin-10 receptor activityPlasma membraneHomo sapiensInterleukin-10 receptor subunit alpha 2.60.40.10 102 11 83 3.66 4.39
1dn0D02 77.78 2.60.40.10 94 7 87 4.13 4.71
1owwA00 77.72 FibronectinER-Golgi intermediate compartmentPeptide cross-linkingFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 93 4 80 3.87 4.81
1fnhA02 77.64 FibronectinPeptide cross-linkingER-Golgi intermediate compartmentFibrinogen complexSubstrate adhesion-dependent cell spreading 2.60.40.10 90 2 83 3.92 4.69
3bgaA04 77.55 Galactose metabolismBacteroides thetaiotaomicronBeta-galactosidaseSphingolipid metabolismBeta-galactosidase [EC:3.2.1.23] 2.60.40.320 105 6 82 3.69 4.45
1ej6A05 77.20 Mammalian orthoreovirus 3 DearingOuter capsid protein lambda-2 2.60.40.10 95 4 81 3.48 4.27
2ny1B02 77.05 Zinc ion bindingMaintenance of protein location in cellT-cell surface glycoprotein CD4Signal transductionT cell receptor signaling pathway 2.60.40.10 75 9 73 3.29 4.49
1wzlA01 76.47 Neopullulanase 2Thermoactinomyces vulgaris 2.60.40.10 121 7 74 3.48 4.68
1hxmB02 76.20 Homo sapiensT-cell receptor gamma-2 chain C region 2.60.40.10 105 6 85 4.28 4.99
1xiwA00 75.91 Chagas diseaseHematopoietic cell lineageReceptor signaling protein activitySH3 domain bindingT cell receptor signaling pathway 2.60.40.10 91 3 75 3.44 4.57
1j0hA01 75.64 NeopullulanaseGeobacillus stearothermophilus 2.60.40.10 125 3 70 3.17 4.50
3d85D03 75.56 2.60.40.10 81 9 81 4.05 4.97
1o7dC02 75.56 Lysosomal alpha-mannosidase [EC:3.2.1.24]LysosomeBos taurusLysosomal alpha-mannosidaseOther glycan degradation 2.60.40.1180 89 5 72 3.28 4.55
1c7sA04 75.38 ChitobiaseSerratia marcescens 2.60.40.320 66 9 65 3.07 4.65
1b4rA00 75.34 Integral to plasma membranePolycystin-1Homophilic cell adhesionHomo sapiensProtein binding 2.60.40.670 80 3 78 3.80 4.85
1ix2A00 74.90 Escherichia coliCopper resistance protein C 2.60.40.1220 97 8 82 3.98 4.83
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Displaying entries 1 to 55 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1eerC01
GPEELLCFTERLEDLVCFWEEAASAGVGPGQYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVT
AASGAPRYHRVIHINEV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1eerC01
GPEELLCFTERLEDLVCFWEEAASAGVGPGQYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVT
AASGAPRYHRVIHINEV
BLAST against CATH

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Domain History Events (4)

Classification merge by cuff on 16 Jun 2009 15:28

COMMENT: merge 2.60.40.30 -> 2.60.40.10 FINAL: superfamily merge

Set cath from cathlist by auto on 05 Mar 2006 18:40

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:40

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:27

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"