CATH Domain: 1eaxA02 XML data for domain: 1eaxA02

Molscript image for 1eaxA02
1eaxA02
PDB coordinates for domain 1eaxA02

PDB 1eax, Chain A, Domain 2

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.12
2.40.10.10.12.1
2.40.10.10.12.1.1
2.40.10.10.12.1.1.1
2.40.10.10.12.1.1.1.1

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Segment boundaries for domain 1eaxA02

Chopping figure for domain 1eaxA02
DomainStart PDB ResidueStop PDB Residue
1eaxA01 16 27
1eaxA01 121 232
1eaxA02 28 120
1eaxA02 233 244

Structural Neighbourhood (30 entries)

There are 30 matching structural neighberhood comparisons for CATH ID 2.40.10.10.12.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 30 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1ym0A02 92.52 Eisenia fetidaLumbrokinase F238 2.40.10.10 112 25 93 1.48 1.58
2anyA02 92.34 Serine-type endopeptidase activityExtracellular spaceCytoplasmPlasminogen activationHomo sapiens 2.40.10.10 111 35 93 1.96 2.09
2wphS02 91.93 Serine-type endopeptidase activityCoagulation factor IX (Christmas factor) [EC:3.4.21.22]Homo sapiensComplement and coagulation cascadesCoagulation factor IX 2.40.10.10 108 37 91 1.54 1.69
1fiwA02 91.78 Ovis ariesAcrosinDrug binding 2.40.10.10 120 30 91 1.53 1.67
2jkhA02 91.53 Serine-type endopeptidase activityPositive regulation of cell migrationProtein bindingComplement and coagulation cascadesHomo sapiens 2.40.10.10 105 28 91 1.40 1.53
1gvzA02 91.39 Equus caballusKallikrein-1E2 2.40.10.10 115 27 89 1.75 1.95
1bioA02 91.30 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 106 32 92 1.63 1.77
1gj7B02 91.28 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorProteolysisExtracellular space 2.40.10.10 118 27 91 1.25 1.37
2r0lA02 91.18 Serine-type endopeptidase activityHomo sapiensHepatocyte growth factor activatorProtein bindingProteolysis 2.40.10.10 113 26 92 1.44 1.56
1nn6A02 91.12 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 107 28 90 1.68 1.86
1a7sA02 91.08 AzurocidinPositive regulation of phagocytosisAzurophil granuleMonocyte activationPositive regulation of tumor necrosis factor biosynthetic process 2.40.10.10 105 27 89 1.55 1.73
1orfA02 90.88 Serine-type endopeptidase activityGranzyme A [EC:3.4.21.78]Protein homodimerization activityNucleusCleavage of lamin 2.40.10.10 105 25 90 1.48 1.64
3govB02 90.69 Serine-type endopeptidase activityCalcium ion bindingProtein homodimerization activityExtracellular spaceProtein binding 2.40.10.10 123 32 91 2.42 2.63
1p57B02 90.69 Serine protease hepsinIntegral to plasma membraneHepsin (transmembrane protease, serine 1) [EC:3.4.21.-]Homo sapiens 2.40.10.10 118 31 89 1.84 2.05
2qxiA02 89.61 Epidermis developmentKallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117]Homo sapiensKallikrein-7 2.40.10.10 98 30 83 1.84 2.20
2hlcA01 89.44 CollagenaseHypoderma lineatum 2.40.10.10 104 34 86 2.64 3.07
2aiqA02 89.09 Agkistrodon contortrix contortrixAncrod 2.40.10.10 113 23 88 2.20 2.48
2asuB02 88.57 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 103 28 88 2.26 2.55
1elvA01 88.56 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 98 26 79 1.62 2.05
1q3xA03 88.42 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 100 22 86 1.77 2.06
3beuA02 87.49 Streptomyces griseusTrypsin 2.40.10.10 99 26 85 2.78 3.26
1rrkA02 86.86 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 117 20 76 2.64 3.43
1agjA02 84.68 Exfoliative toxin AStaphylococcus aureus 2.40.10.10 108 19 86 2.70 3.10
1p3cA02 83.98 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 107 16 90 2.97 3.28
2o8lA02 83.07 Glutamyl endopeptidase [EC:3.4.21.19]Glutamyl endopeptidaseStaphylococcus aureus subsp. aureus Mu50 2.40.10.10 101 12 77 2.77 3.58
2pkaA00 82.63 Sus scrofaGlandular kallikrein 2.40.10.10 80 27 59 1.79 3.03
1sotA01 80.14 Escherichia coli O157:H7Protease degSSerine protease DegS [EC:3.4.21.-] 2.40.10.10 118 9 72 3.28 4.55
1lcyA01 79.56 Serine-type endopeptidase activityHtrA serine peptidase 2 [EC:3.4.21.108]Parkinson's diseaseEndoplasmic reticulum membraneNucleus 2.40.10.10 111 13 70 2.56 3.63
2halA01 77.76 Human hepatitis A virus Hu/Australia/HM175/1976Genome polyprotein 2.40.10.10 109 11 79 3.43 4.33
1eptA00 68.02 Sus scrofaTrypsin 2.40.10.10 43 44 26 1.10 4.08
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Displaying entries 1 to 30 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1eaxA02
PWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDF
TFDYDIALLELEKPAEYSSMVRPLFRDWIKENTGV
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1eaxA02
PWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDF
TFDYDIALLELEKPAEYSSMVRPLFRDWIKENTGV
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:26

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"