CATH Domain: 1eaxA01 XML data for domain: 1eaxA01

Molscript image for 1eaxA01
1eaxA01
PDB coordinates for domain 1eaxA01

PDB 1eax, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.32
2.40.10.10.32.1
2.40.10.10.32.1.1
2.40.10.10.32.1.1.1
2.40.10.10.32.1.1.1.1

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Segment boundaries for domain 1eaxA01

Chopping figure for domain 1eaxA01
DomainStart PDB ResidueStop PDB Residue
1eaxA01 16 27
1eaxA01 121 232
1eaxA02 28 120
1eaxA02 233 244

Structural Neighbourhood (20 entries)

There are 20 matching structural neighberhood comparisons for CATH ID 2.40.10.10.32.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 20 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
2bvrH01 92.70 FibrinolysisSerine-type endopeptidase activityProthrombinSoluble fractionPositive regulation of protein phosphorylation 2.40.10.10 132 35 94 1.40 1.48
2o8tA01 92.55 Regulation of smooth muscle cell migrationCell surfaceUrokinase-type plasminogen activatorSignal transductionProteolysis 2.40.10.10 128 34 97 1.26 1.29
1k2i101 92.35 Bos taurusChymotrypsinogen A 2.40.10.10 118 39 93 1.31 1.40
3gylB01 91.72 ProstasinPlasma membraneProtease, serine, 8 (prostasin) [EC:3.4.21.-]Homo sapiensExtracellular space 2.40.10.10 133 43 93 1.50 1.61
1q3xA02 91.69 Serine-type endopeptidase activityHomo sapiensMannan-binding lectin serine protease 2Calcium-dependent protein bindingComplement activation, lectin pathway 2.40.10.10 137 35 91 1.46 1.60
1eq9A01 91.30 Chymotrypsin-1Solenopsis invicta 2.40.10.10 117 37 92 1.28 1.38
1elvA02 90.68 Serine-type endopeptidase activitySystemic lupus erythematosusComplement C1s subcomponentHomo sapiensComplement component 1, s subcomponent [EC:3.4.21.42] 2.40.10.10 126 34 95 2.07 2.17
1bioA01 90.35 Serine-type endopeptidase activityHomo sapiensComponent factor D [EC:3.4.21.46]Complement and coagulation cascadesComplement factor D 2.40.10.10 122 32 94 1.50 1.59
2asuB01 89.86 Hepatocyte growth factor-like proteinHomo sapiens 2.40.10.10 122 31 96 2.18 2.27
2hlcA02 89.17 CollagenaseHypoderma lineatum 2.40.10.10 126 29 93 1.84 1.96
1si5H01 88.75 Pathways in cancerHepatocyte growth factorEpithelial to mesenchymal transitionRenal cell carcinomaCytokine-cytokine receptor interaction 2.40.10.10 119 29 93 2.21 2.36
1nn6A01 84.32 ChymaseChymase [EC:3.4.21.39]Homo sapiensRenin-angiotensin systemInterleukin-1 beta biosynthetic process 2.40.10.10 114 29 90 2.76 3.05
1yphE00 84.10 Bos taurusChymotrypsinogen A 2.40.10.10 97 29 66 1.66 2.49
2qf3B02 80.87 Protease degSProtein bindingSerine protease DegS [EC:3.4.21.-]Escherichia coli K-12 2.40.10.10 103 11 72 2.82 3.90
1y8tB02 80.79 Two-component systemPutative serine protease PepD [EC:3.4.21.-]PROBABLE SERINE PROTEASE PEPD (SERINE PROTEINASE) (MTB32B)Mycobacterium tuberculosis 2.40.10.10 111 13 72 2.95 4.08
1dleB02 80.77 Complement factor BComplement bindingHomo sapiensComponent factor B [EC:3.4.21.47]Complement and coagulation cascades 2.40.10.10 142 23 71 2.19 3.05
1p3cA01 79.11 Glutamyl-endopeptidaseBacillus intermedius 2.40.10.10 102 13 77 3.49 4.49
2j92A02 78.94 Foot-and-mouth disease virus (strain A10-61)Genome polyprotein 2.40.10.10 109 9 75 3.64 4.83
1svpA02 72.87 Sindbis virusStructural polyprotein 2.40.10.10 86 9 55 2.37 4.27
3fanA02 70.86 Porcine reproductive and respiratory syndrome virusNon-structural protein 2.40.10.10 69 14 50 2.31 4.62
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Displaying entries 1 to 20 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1eaxA01
VVGGTDADEGEWICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGG
VDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLP
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1eaxA01
VVGGTDADEGEWICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITPRMMCVGFLSGG
VDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTRLP
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 18:27

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:26

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"