CATH Domain: 1e6uA01 XML data for domain: 1e6uA01

Molscript image for 1e6uA01
1e6uA01
PDB coordinates for domain 1e6uA01

PDB 1e6u, Chain A, Domain 1

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.720 NAD(P)-binding Rossmann-like Domain Gene3D
3.40.50.720.15
3.40.50.720.15.1
3.40.50.720.15.1.1
3.40.50.720.15.1.1.1
3.40.50.720.15.1.1.1.1

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Segment boundaries for domain 1e6uA01

Chopping figure for domain 1e6uA01
DomainStart PDB ResidueStop PDB Residue
1e6uA01 3 167
1e6uA01 210 248
1e6uA01 284 299
1e6uA02 168 209
1e6uA02 249 283
1e6uA02 300 316

Structural Neighbourhood (38 entries)

There are 38 matching structural neighberhood comparisons for CATH ID 3.40.50.720.15.1.1.1.1 (SIMAX score < 5)

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Displaying entries 1 to 38 (page 1 of 1)
Match Depth Match SSAP score Match Keywords Match Superfamily Length Sequence Id Overlap RMSD SIMAX
1n7hA02 87.61 Amino sugar and nucleotide sugar metabolismGDPmannose 4,6-dehydratase [EC:4.2.1.47]Fructose and mannose metabolismCytosolMetabolic pathways 3.40.50.720 231 18 87 1.84 2.11
1vl0B01 86.87 DTDP-4-dehydrorhamnose reductase, rfbD orthologDTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesis 3.40.50.720 200 19 88 1.99 2.26
1ek6A02 86.10 Amino sugar and nucleotide sugar metabolismGalactose metabolismUDP-glucose 4-epimeraseProtein homodimerization activityUDP-glucose 4-epimerase activity 3.40.50.720 218 17 85 2.21 2.57
1kbzA01 85.21 Streptomycin biosynthesisMetabolic pathwaysPolyketide sugar unit biosynthesisDTDP-4-dehydrorhamnose reductaseSalmonella enterica subsp. enterica serovar Typhimurium 3.40.50.720 213 15 89 2.13 2.38
2bllA01 83.66 Amino sugar and nucleotide sugar metabolismOxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorHydroxymethyl-, formyl- and related transferase activityUDP-GlcUA decarboxylase/UDP-L-Ara4N formyltransferase [EC:1.1.1.- 2.1.2.-]Bifunctional polymyxin resistance protein ArnA 3.40.50.720 243 15 85 2.73 3.20
2hrzA01 83.51 Agrobacterium tumefaciens str. C58Nucleoside-diphosphate-sugar epimerase 3.40.50.720 224 15 86 3.36 3.90
1wvgA01 82.95 3.40.50.720 193 15 70 2.00 2.86
1i24A01 82.71 Amino sugar and nucleotide sugar metabolismZinc ion bindingGlycolipid biosynthetic processChloroplastSulfotransferase activity 3.40.50.720 235 11 77 2.69 3.47
1eq2A01 82.64 Metabolic pathwaysLipopolysaccharide biosynthesisMembraneProtein bindingADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] 3.40.50.720 202 12 83 2.68 3.22
3e8xA00 82.42 BH1520 proteinBacillus halodurans 3.40.50.720 204 15 79 3.54 4.48
2ztuB00 81.82 Pseudomonas fragiD(-)-3-hydroxybutyrate dehydrogenase 3.40.50.720 207 12 82 3.24 3.94
3grpD00 81.77 3-oxoacyl-(Acyl carrierprotein) reductaseBartonella henselae3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 209 12 76 2.60 3.40
3d7lA00 81.34 Listeria innocuaLin1944 protein 3.40.50.720 196 12 77 3.05 3.92
2z1nA00 81.16 Aeropyrum pernix3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Putative dehydrogenaseFatty acid biosynthesisBiosynthesis of unsaturated fatty acids 3.40.50.720 237 9 77 2.83 3.65
2ew8B00 81.03 Ethylbenzene degradation(S)-1-Phenylethanol dehydrogenaseAromatoleum aromaticum EbN1 3.40.50.720 228 11 81 2.99 3.68
1zemA00 80.85 Gluconobacter oxydansXylitol dehydrogenase 3.40.50.720 260 11 69 2.49 3.58
1gz6B01 80.83 PeroxisomeRattus norvegicusPrimary bile acid biosynthesis3(or 17)beta-hydroxysteroid dehydrogenase activityPeroxisomal multifunctional enzyme type 2 3.40.50.720 219 12 80 3.27 4.06
2a4kB01 80.82 3.40.50.720 196 12 69 2.67 3.84
2ag5C00 80.81 NAD or NADH bindingMetabolic pathwaysButanoate metabolismCytoplasm3-hydroxybutyrate dehydrogenase type 2 3.40.50.720 244 11 75 2.74 3.61
2p91C00 80.79 Enoyl-[acyl-carrier-protein] reductase [NADH]Aquifex aeolicus 3.40.50.720 228 7 81 3.44 4.24
1hxhA00 80.71 3-beta-hydroxysteroid dehydrogenaseComamonas testosteroni 3.40.50.720 253 9 73 3.57 4.83
1xg5B00 80.56 Dehydrogenase/reductase SDR family member 11Homo sapiens 3.40.50.720 241 15 74 2.95 3.97
1cydA00 80.55 Carbonyl reductase (NADPH) activityArachidonic acid metabolismProtein tetramerizationCarbonyl reductase [NADPH] 2Metabolic pathways 3.40.50.720 242 15 76 2.99 3.91
1spxA00 80.45 Caenorhabditis elegansProtein D1054.8, confirmed by transcript evidenceDetermination of adult lifespan 3.40.50.720 237 10 75 2.86 3.81
1iy8A00 80.20 Leifsonia aquaticaLevodione reductase 3.40.50.720 258 12 72 2.88 3.99
2ekpA00 80.05 Pentose and glucuronate interconversionsThermus thermophilus HB82-deoxy-D-gluconate 3-dehydrogenase2-deoxy-D-gluconate 3-dehydrogenase [EC:1.1.1.125] 3.40.50.720 238 13 78 3.33 4.26
2rhcA00 80.02 Putative ketoacyl reductaseBiosynthesis of type II polyketide backboneStreptomyces coelicolorKetoacyl reductase [EC:1.3.1.-] 3.40.50.720 257 10 70 2.48 3.52
1zk4A00 79.79 Lactobacillus brevisR-specific alcohol dehydrogenase 3.40.50.720 244 11 74 3.07 4.12
1ja9A00 79.79 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]Fatty acid biosynthesis1,3,6,8-tetrahydroxynaphthalene reductaseBiosynthesis of unsaturated fatty acidsMagnaporthe grisea 3.40.50.720 259 11 71 3.09 4.35
2zatA00 79.65 PeroxisomeDehydrogenase/reductase SDR family member 4 [EC:1.1.-.-]Sus scrofaDehydrogenase/reductase SDR family member 4Retinol metabolism 3.40.50.720 251 13 74 3.04 4.10
3gemD00 79.56 Pseudomonas syringae pv. phaseolicola 1448A[EC:1.-.-.-]Oxidoreductase, short chain dehydrogenase/reductase family 3.40.50.720 209 10 81 3.29 4.02
1xq1A00 79.30 Arabidopsis thalianaTropinone reductase homolog At1g07440Response to cadmium ion 3.40.50.720 218 11 76 3.09 4.02
1ooeA00 79.23 Dihydropteridine reductase [EC:1.5.1.34]Caenorhabditis elegansProtein T03F6.1, confirmed by transcript evidenceFolate biosynthesisMetabolic pathways 3.40.50.720 235 15 81 3.94 4.85
3iccA00 79.12 Bacillus anthracisOxidoreductase, short-chain dehydrogenase/reductase family 3.40.50.720 248 14 73 2.93 3.99
2qq5A00 78.90 NucleusGolgi apparatusEndoplasmic reticulumHomo sapiensDehydrogenase/reductase SDR family member 1 3.40.50.720 238 12 77 2.96 3.83
1oaaA00 78.02 DeathRegulation of multicellular organism growthProtein homodimerization activitySepiapterin reductasePteridine metabolic process 3.40.50.720 259 10 69 3.01 4.33
2axqA01 76.91 Lysine biosynthetic process via aminoadipic acidIdentical protein bindingSaccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]Saccharopine dehydrogenase [NADP+, L-glutamate-forming]Metabolic pathways 3.40.50.720 174 11 66 3.34 5.00
2h7iA00 76.53 Enoyl-[acyl-carrier-protein] reductase [NADH]Enoyl ACP reductase [EC:1.3.1.9]Mycobacterium tuberculosis 3.40.50.720 268 10 69 3.39 4.88
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Displaying entries 1 to 38 (page 1 of 1)


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Domain ATOM Sequence 

>pdb|1e6uA01
KQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ
NMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVM
PTNLYEFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGLLDVTRLHQLGWYHEI
BLAST against CATH

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Domain COMBS Sequence 

>pdb|1e6uA01
KQRVFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQ
NMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVM
PTNLYEFLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGLLDVTRLHQLGWYHEI
BLAST against CATH

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Domain History Events (3)

Set cath from cathlist by auto on 05 Mar 2006 19:16

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Flow stage update by auto on 05 Mar 2006 19:16

This domain was assigned by cathlist2DB and was parsed from the cath list "/usr/local/cvs/source/lists/CathList"

Insertion by auto on 05 Mar 2006 16:25

PDB chopped based on information from the domall file "/usr/local/cvs/source/lists/CathDomall"